Last updated: 2016-08-16

Code version: e0856a352e494c0de5f1f93226e04753d2aebdca

This is an example of using the package maSigPro. It was originally created to find significant gene expression profile differences in time course microarray data. It was later revised to be able to run on expression data from RNA-seq (see http://www.ncbi.nlm.nih.gov/pubmed/16481333 and http://www.ncbi.nlm.nih.gov/pubmed/24894503, respectively).

# Load the libraries

# source("http://bioconductor.org/biocLite.R")
# biocLite("maSigPro")
library("maSigPro")
Loading required package: Biobase
Loading required package: BiocGenerics
Loading required package: parallel

Attaching package: 'BiocGenerics'
The following objects are masked from 'package:parallel':

    clusterApply, clusterApplyLB, clusterCall, clusterEvalQ,
    clusterExport, clusterMap, parApply, parCapply, parLapply,
    parLapplyLB, parRapply, parSapply, parSapplyLB
The following objects are masked from 'package:stats':

    IQR, mad, xtabs
The following objects are masked from 'package:base':

    anyDuplicated, append, as.data.frame, cbind, colnames,
    do.call, duplicated, eval, evalq, Filter, Find, get, grep,
    grepl, intersect, is.unsorted, lapply, lengths, Map, mapply,
    match, mget, order, paste, pmax, pmax.int, pmin, pmin.int,
    Position, rank, rbind, Reduce, rownames, sapply, setdiff,
    sort, table, tapply, union, unique, unsplit
Welcome to Bioconductor

    Vignettes contain introductory material; view with
    'browseVignettes()'. To cite Bioconductor, see
    'citation("Biobase")', and for packages 'citation("pkgname")'.
Loading required package: MASS
# Load the data

# From the maSigPro vignette
data(NBdata)
head(NBdata)
      G1.T1.1 G1.T1.2 G1.T1.3 G1.T2.1 G1.T2.2 G1.T2.3 G1.T3.1 G1.T3.2
Gene1      11       8      11       8       9       6      12       5
Gene2       8      11       5       3      10       9       6      22
Gene3      13       6       4       8      18       5      11      18
Gene4       7      11      13       7       8      11       8      11
Gene5      17       8       6       7       4       5      13      10
Gene6      14      19       4      13       4      10       5      10
      G1.T3.3 G1.T4.1 G1.T4.2 G1.T4.3 G1.T5.1 G1.T5.2 G1.T5.3 G1.T6.1
Gene1      11       9       4      12      20      10       3       2
Gene2       9       7       8       3       6       7       6       8
Gene3       9       8      17       5       7       5       6       8
Gene4      14       5       3      12       3      11       3       8
Gene5      15       8      20       8       5       8      10       9
Gene6      20      12      13      11       3       7       8       7
      G1.T6.2 G1.T6.3 G2.T1.1 G2.T1.2 G2.T1.3 G2.T2.1 G2.T2.2 G2.T2.3
Gene1       6      17      16       3      11      44      36      38
Gene2       5       8       7       9       3      45      66      36
Gene3       6       9       7       7      13      38      34      42
Gene4       5       8      12      10       2      55      54      33
Gene5      16      11       6       5      15      13      63      19
Gene6      12      10       8      11       9      16      36      25
      G2.T3.1 G2.T3.2 G2.T3.3 G2.T4.1 G2.T4.2 G2.T4.3 G2.T5.1 G2.T5.2
Gene1      59      33      34      67      85      93      86      37
Gene2      34      79      38     136      99      69     160      38
Gene3      80      40      37      56      93      73     142     104
Gene4      64      86      36      85      27     132      82     104
Gene5      60      27      24      96      93      50      84      66
Gene6      57      73      51      21     115      55      90     119
      G2.T5.3 G2.T6.1 G2.T6.2 G2.T6.3
Gene1     178     121     208      45
Gene2      51     122     150     182
Gene3     105     149     130     106
Gene4      94      93     122     142
Gene5      70      79     199     207
Gene6      64      54      55     107
data(NBdesign)
head(NBdesign)
        Time Replicates Group.1 Group.2
G1.T1.1    0          1       1       0
G1.T1.2    0          1       1       0
G1.T1.3    0          1       1       0
G1.T2.1   12          2       1       0
G1.T2.2   12          2       1       0
G1.T2.3   12          2       1       0
# We will also run this using the endotoxin_data from the edge vignette

endotoxin_data <- read.delim("../data/endotoxin_data.txt")

Using the maSigPro vignette

# Make a design matrix

d <- make.design.matrix(NBdesign)

# Look at the design matrix

head(d$dis)
        Group.2vsGroup.1 Time TimexGroup.2 Time2 Time2xGroup.2
G1.T1.1                0    0            0     0             0
G1.T1.2                0    0            0     0             0
G1.T1.3                0    0            0     0             0
G1.T2.1                0   12            0   144             0
G1.T2.2                0   12            0   144             0
G1.T2.3                0   12            0   144             0
# Look at the assignment of regression variables to experimental groups

d$groups.vector
[1] "Group.2vsGroup.1" "Group.1"          "Group.2vsGroup.1"
[4] "Group.1"          "Group.2vsGroup.1"
# We are using theta = 10

# Compute a regression fit for each gene. Comupte a p-value associated with the F-statistic of the model (FDR = 10%)

NB_p_vector <- p.vector(NBdata, d, counts = TRUE, theta = 10, Q = 0.10, MT.adjust = "BH")
[1] "fitting gene 100 out of 100"
# Find the number of significant genes

NB_p_vector$i
[1] 21
# Find the p-value at the 10% false discovery control level

NB_p_vector$p.adjusted
  [1] 1.496325e-36 9.945124e-41 2.633579e-71 2.062136e-53 2.546722e-30
  [6] 9.299635e-40 7.219520e-45 9.322756e-62 3.386832e-46 3.088960e-31
 [11] 1.884163e-25 6.118179e-17 2.252251e-18 7.787709e-26 2.269186e-11
 [16] 1.920044e-09 4.893671e-15 4.865905e-23 3.919473e-27 1.345130e-23
 [21] 9.157638e-01 8.664468e-01 8.664468e-01 7.173207e-01 9.157638e-01
 [26] 5.669636e-01 8.664468e-01 4.657497e-01 1.010957e-01 9.806395e-01
 [31] 8.664468e-01 7.173207e-01 3.876466e-01 7.173207e-01 9.806395e-01
 [36] 6.070586e-01 8.098490e-01 6.932788e-01 8.988446e-01 9.806395e-01
 [41] 8.664468e-01 8.664468e-01 9.806395e-01 3.971631e-01 8.664468e-01
 [46] 9.806395e-01 8.664468e-01 8.664468e-01 5.791164e-01 9.806395e-01
 [51] 6.932788e-01 3.471490e-02 8.664468e-01 9.806395e-01 6.070586e-01
 [56] 7.173207e-01 4.823197e-01 8.664468e-01 9.806395e-01 8.140728e-01
 [61] 2.462303e-01 5.464465e-01 5.464465e-01 4.718576e-01 8.664468e-01
 [66] 8.664468e-01 8.664468e-01 8.664468e-01 6.941345e-01 9.157638e-01
 [71] 7.508890e-01 7.755715e-01 5.464465e-01 8.366649e-01 8.664468e-01
 [76] 6.932788e-01 3.971631e-01 9.244852e-01 4.718576e-01 8.664468e-01
 [81] 7.173207e-01 9.806395e-01 8.140728e-01 8.098490e-01 9.806395e-01
 [86] 9.164062e-01 7.173207e-01 8.988446e-01 9.806395e-01 8.635561e-01
 [91] 9.806395e-01 6.932788e-01 6.932788e-01 2.217853e-01 5.464465e-01
 [96] 5.464465e-01 8.664468e-01 9.069686e-01 9.806395e-01 6.593966e-01
# A matrix with the significant genes and their expression values

head(NB_p_vector$SELEC)
      G1.T1.1 G1.T1.2 G1.T1.3 G1.T2.1 G1.T2.2 G1.T2.3 G1.T3.1 G1.T3.2
Gene1      11       8      11       8       9       6      12       5
Gene2       8      11       5       3      10       9       6      22
Gene3      13       6       4       8      18       5      11      18
Gene4       7      11      13       7       8      11       8      11
Gene5      17       8       6       7       4       5      13      10
Gene6      14      19       4      13       4      10       5      10
      G1.T3.3 G1.T4.1 G1.T4.2 G1.T4.3 G1.T5.1 G1.T5.2 G1.T5.3 G1.T6.1
Gene1      11       9       4      12      20      10       3       2
Gene2       9       7       8       3       6       7       6       8
Gene3       9       8      17       5       7       5       6       8
Gene4      14       5       3      12       3      11       3       8
Gene5      15       8      20       8       5       8      10       9
Gene6      20      12      13      11       3       7       8       7
      G1.T6.2 G1.T6.3 G2.T1.1 G2.T1.2 G2.T1.3 G2.T2.1 G2.T2.2 G2.T2.3
Gene1       6      17      16       3      11      44      36      38
Gene2       5       8       7       9       3      45      66      36
Gene3       6       9       7       7      13      38      34      42
Gene4       5       8      12      10       2      55      54      33
Gene5      16      11       6       5      15      13      63      19
Gene6      12      10       8      11       9      16      36      25
      G2.T3.1 G2.T3.2 G2.T3.3 G2.T4.1 G2.T4.2 G2.T4.3 G2.T5.1 G2.T5.2
Gene1      59      33      34      67      85      93      86      37
Gene2      34      79      38     136      99      69     160      38
Gene3      80      40      37      56      93      73     142     104
Gene4      64      86      36      85      27     132      82     104
Gene5      60      27      24      96      93      50      84      66
Gene6      57      73      51      21     115      55      90     119
      G2.T5.3 G2.T6.1 G2.T6.2 G2.T6.3
Gene1     178     121     208      45
Gene2      51     122     150     182
Gene3     105     149     130     106
Gene4      94      93     122     142
Gene5      70      79     199     207
Gene6      64      54      55     107
# Execute the stepwise (forward) regression. At each regression step, the p-value of each variable is computed and variables get in/out when the p-value is lower/higher than the given cutoff (alfa). 

NB_t_stat <- T.fit(NB_p_vector)

# p-value of the regression ANOVA, R-squared of the model, and p-value of the regression coefficients of the selected variables

head(NB_t_stat$sol)
           p-value R-squared p.valor_beta0 p.valor_Group.2vsGroup.1
Gene1 8.725223e-42 0.8368073  1.929619e-19                       NA
Gene2 5.481191e-43 0.8589217  3.343108e-17                       NA
Gene3 2.343926e-75 0.9204022  3.400685e-11                0.0433835
Gene4 1.036785e-58 0.8781336  7.187104e-17                       NA
Gene5 5.476285e-32 0.8379997  9.284463e-20                       NA
Gene6 1.041572e-44 0.8440434  5.238118e-22                       NA
      p.valor_Time p.valor_TimexGroup.2 p.valor_Time2
Gene1           NA         1.142500e-07            NA
Gene2           NA         1.096233e-08            NA
Gene3   0.01364611         2.881477e-07   0.002480463
Gene4   0.04094617         2.218442e-10            NA
Gene5           NA         8.484448e-13            NA
Gene6           NA         1.492607e-09            NA
      p.valor_Time2xGroup.2
Gene1          1.935202e-03
Gene2          2.216415e-04
Gene3                    NA
Gene4          1.220671e-04
Gene5                    NA
Gene6          2.289293e-05
# Obtaining lists of significant genes for each experimental group. We can set and R-squared value so that the models must be greater than 0.2.

get_NB_genes <- get.siggenes(NB_t_stat, rsq = 0.2, var = "groups")

# Get the lists of significant genes

  # The first list (Group.1) contains genes whose expression is significantly different from a 0 profile in the reference group. 
  # The second list (Group.2vsGroup.1) contains differentially expressed curves.  We are most interested in the second list because it contains genes whose profiles for the experimental group is different from the reference group. 

names(get_NB_genes$sig.genes)
[1] "Group.1"          "Group.2vsGroup.1"
get_NB_genes$summary
   Group.1 Group.2vsGroup.1
1    Gene3            Gene1
2    Gene4            Gene2
3   Gene10            Gene3
4   Gene15            Gene4
5   Gene16            Gene5
6   Gene18            Gene6
7   Gene52            Gene7
8                     Gene8
9                     Gene9
10                   Gene10
11                   Gene11
12                   Gene12
13                   Gene13
14                   Gene14
15                   Gene15
16                   Gene16
17                   Gene17
18                   Gene18
19                   Gene19
20                   Gene20
21                   Gene52
get_NB_genes$sig.genes$Group.2vsGroup.1
$sig.profiles
       G1.T1.1 G1.T1.2 G1.T1.3 G1.T2.1 G1.T2.2 G1.T2.3 G1.T3.1 G1.T3.2
Gene1       11       8      11       8       9       6      12       5
Gene2        8      11       5       3      10       9       6      22
Gene3       13       6       4       8      18       5      11      18
Gene4        7      11      13       7       8      11       8      11
Gene5       17       8       6       7       4       5      13      10
Gene6       14      19       4      13       4      10       5      10
Gene7       15       5       5       9       7       9      10      14
Gene8        7       8      13       7      10       5      13      16
Gene9       13      12      11       3       3       5       5      16
Gene10       5       4       4      14      16       9       8       9
Gene11      95     138      94     103     128     118     114     137
Gene12     139     130      40      56     223     126     137     150
Gene13     158      42      88     155     102     213     126     141
Gene14      71      90     132     144      57     114     130      61
Gene15      91      28      44      75      62      86      79     114
Gene16      77      84     105     188      34     164      81     133
Gene17      85      78      73     190      64     177      43      84
Gene18     157      99     137      85      48      79      70      70
Gene19     174     144      91     143     125     139     117     120
Gene20     176     170      64      43     105      40     121     172
Gene52       1       1       1       1       1       1       1       0
       G1.T3.3 G1.T4.1 G1.T4.2 G1.T4.3 G1.T5.1 G1.T5.2 G1.T5.3 G1.T6.1
Gene1       11       9       4      12      20      10       3       2
Gene2        9       7       8       3       6       7       6       8
Gene3        9       8      17       5       7       5       6       8
Gene4       14       5       3      12       3      11       3       8
Gene5       15       8      20       8       5       8      10       9
Gene6       20      12      13      11       3       7       8       7
Gene7        7       7      10       4       3       8       4       1
Gene8        4       8      10      14      11       7       4      18
Gene9       12       8       8       5       8       9      10       5
Gene10       5      12      15       6      11      15      10       7
Gene11      82      91      63      81     128      78     106     170
Gene12      91      70     214     219     119     113      76     123
Gene13     119     115     163     153      51     134     132      91
Gene14     121      68      54      90     116     128     152      58
Gene15     113      93     219     129     141     126     173      42
Gene16     156      37      76      50      56      85     134      38
Gene17      96      87      92      53      51      87     156     116
Gene18     117     163     123      63      66     137      93     105
Gene19     110     116      94     181     120      83      82     150
Gene20     103     101      86     117      78     144     138     106
Gene52       1       0       1       0       1       1       0       1
       G1.T6.2 G1.T6.3 G2.T1.1 G2.T1.2 G2.T1.3 G2.T2.1 G2.T2.2 G2.T2.3
Gene1        6      17      16       3      11      44      36      38
Gene2        5       8       7       9       3      45      66      36
Gene3        6       9       7       7      13      38      34      42
Gene4        5       8      12      10       2      55      54      33
Gene5       16      11       6       5      15      13      63      19
Gene6       12      10       8      11       9      16      36      25
Gene7       21       8       5       2      11      46      23      46
Gene8        7       8       3       4       8      24      12      35
Gene9        5      14      20      14       7      34      52      33
Gene10       8      14       8       5      17      37       9      15
Gene11      80      96      58     121     109      52      32      33
Gene12     123     162      82     110     118      76      99      67
Gene13     102     102     226      59     215     146     134      95
Gene14     179      90     122      77     121     156     105      76
Gene15     183     118      81      86     263      35     125      96
Gene16      63      62      52     155      87      64      33      54
Gene17      60      70     108      76     145     150     234      88
Gene18     191     175      52      66     110      96      84     111
Gene19     189      90     167     151     221      61     179      71
Gene20     139     100      70      82      65      30     130      84
Gene52       1       1       1       1       2       1       2       1
       G2.T3.1 G2.T3.2 G2.T3.3 G2.T4.1 G2.T4.2 G2.T4.3 G2.T5.1 G2.T5.2
Gene1       59      33      34      67      85      93      86      37
Gene2       34      79      38     136      99      69     160      38
Gene3       80      40      37      56      93      73     142     104
Gene4       64      86      36      85      27     132      82     104
Gene5       60      27      24      96      93      50      84      66
Gene6       57      73      51      21     115      55      90     119
Gene7       51      75      31      89      68     113     155      94
Gene8       64      99      47      82      90     114      92     144
Gene9       18      45      51     104      63      86     169      48
Gene10      65      45      83     145      78      35     123      42
Gene11      67      70      62      48      39      23      15      22
Gene12      57      26      55      32      35      38      32      34
Gene13      36     114      52      28      29      30      32      33
Gene14     123      51      55      24      46      52      23      13
Gene15      67      30      51      77      24      57      24      35
Gene16      90      49      20      44      77      26      14      35
Gene17     109      61      26      47      35      26      27      11
Gene18      47      49      49      27      60      49      24      26
Gene19      29      37     113      47      53      23      18      16
Gene20      42      60      36      54      71      55      15      14
Gene52       1       1       2       1       1       2       0       1
       G2.T5.3 G2.T6.1 G2.T6.2 G2.T6.3
Gene1      178     121     208      45
Gene2       51     122     150     182
Gene3      105     149     130     106
Gene4       94      93     122     142
Gene5       70      79     199     207
Gene6       64      54      55     107
Gene7       87      80     119     108
Gene8       91      70     128     219
Gene9      124      96     115      62
Gene10      31      88     137      55
Gene11      19       0       0       0
Gene12      17       0       0       0
Gene13      17       0       0       0
Gene14      17       0       0       0
Gene15      32       0       0       0
Gene16      14       0       0       0
Gene17      24       0       0       0
Gene18       9       0       0       0
Gene19      25       0       0       0
Gene20      13       0       0       0
Gene52       1       0       1       0

$coefficients
          beta0 betaGroup.2vsGroup.1    betaTime betaTimexGroup.2
Gene1  2.278047            0.0000000  0.00000000       0.08916287
Gene2  2.135603            0.0000000  0.00000000       0.10798362
Gene3  2.033237            0.5040394  0.03070961       0.04306060
Gene4  2.430018            0.0000000 -0.01054742       0.10480146
Gene5  2.412239            0.0000000  0.00000000       0.04617238
Gene6  2.306199            0.0000000  0.00000000       0.09246189
Gene7  2.110912            0.0000000  0.00000000       0.11099396
Gene8  2.179019            0.0000000  0.00000000       0.10110885
Gene9  2.133509            0.5580506  0.00000000       0.07072630
Gene10 1.588042            0.7911197  0.05535127       0.02631331
Gene11 4.619593            0.0000000  0.00000000       0.00000000
Gene12 4.786494            0.0000000  0.00000000       0.00000000
Gene13 4.868857            0.0000000  0.00000000       0.00000000
Gene14 4.626330            0.0000000  0.00000000       0.03562703
Gene15 4.186381            0.5402831  0.01471998       0.00000000
Gene16 4.643251            0.0000000  0.00000000       0.00000000
Gene17 4.559989            0.0000000  0.00000000       0.04300958
Gene18 4.464049            0.0000000  0.00000000       0.03108154
Gene19 4.893843            0.0000000  0.00000000       0.00000000
Gene20 4.712030           -0.5934558  0.00000000       0.05905803
Gene52 0.000000            0.0000000 -0.04602121       0.07181613
           betaTime2 betaTime2xGroup.2
Gene1   0.0000000000     -0.0008019954
Gene2   0.0000000000     -0.0010600359
Gene3  -0.0005845928      0.0000000000
Gene4   0.0000000000     -0.0009603098
Gene5   0.0000000000      0.0000000000
Gene6   0.0000000000     -0.0009941975
Gene7   0.0000000000     -0.0011666488
Gene8   0.0000000000     -0.0009426665
Gene9   0.0000000000     -0.0006509451
Gene10 -0.0007765140      0.0000000000
Gene11  0.0000000000     -0.0009360262
Gene12  0.0000000000     -0.0009294319
Gene13  0.0000000000     -0.0009685171
Gene14  0.0000000000     -0.0016957561
Gene15  0.0000000000     -0.0011350342
Gene16 -0.0001529452     -0.0007319517
Gene17  0.0000000000     -0.0017964008
Gene18  0.0001399779     -0.0016335054
Gene19  0.0000000000     -0.0010407943
Gene20  0.0000000000     -0.0019643847
Gene52  0.0006995632     -0.0014648266

$group.coeffs
       Group.1_beta0 Group.1_beta1 Group.1_beta2 Group.2_beta0
Gene1       2.278047    0.00000000  0.0000000000      2.278047
Gene2       2.135603    0.00000000  0.0000000000      2.135603
Gene3       2.033237    0.03070961 -0.0005845928      2.537276
Gene4       2.430018   -0.01054742  0.0000000000      2.430018
Gene5       2.412239    0.00000000  0.0000000000      2.412239
Gene6       2.306199    0.00000000  0.0000000000      2.306199
Gene7       2.110912    0.00000000  0.0000000000      2.110912
Gene8       2.179019    0.00000000  0.0000000000      2.179019
Gene9       2.133509    0.00000000  0.0000000000      2.691559
Gene10      1.588042    0.05535127 -0.0007765140      2.379162
Gene11      4.619593    0.00000000  0.0000000000      4.619593
Gene12      4.786494    0.00000000  0.0000000000      4.786494
Gene13      4.868857    0.00000000  0.0000000000      4.868857
Gene14      4.626330    0.00000000  0.0000000000      4.626330
Gene15      4.186381    0.01471998  0.0000000000      4.726664
Gene16      4.643251    0.00000000 -0.0001529452      4.643251
Gene17      4.559989    0.00000000  0.0000000000      4.559989
Gene18      4.464049    0.00000000  0.0001399779      4.464049
Gene19      4.893843    0.00000000  0.0000000000      4.893843
Gene20      4.712030    0.00000000  0.0000000000      4.118574
Gene52      0.000000   -0.04602121  0.0006995632      0.000000
       Group.2_beta1 Group.2_beta2
Gene1     0.08916287 -0.0008019954
Gene2     0.10798362 -0.0010600359
Gene3     0.07377021 -0.0005845928
Gene4     0.09425404 -0.0009603098
Gene5     0.04617238  0.0000000000
Gene6     0.09246189 -0.0009941975
Gene7     0.11099396 -0.0011666488
Gene8     0.10110885 -0.0009426665
Gene9     0.07072630 -0.0006509451
Gene10    0.08166458 -0.0007765140
Gene11    0.00000000 -0.0009360262
Gene12    0.00000000 -0.0009294319
Gene13    0.00000000 -0.0009685171
Gene14    0.03562703 -0.0016957561
Gene15    0.01471998 -0.0011350342
Gene16    0.00000000 -0.0008848968
Gene17    0.04300958 -0.0017964008
Gene18    0.03108154 -0.0014935275
Gene19    0.00000000 -0.0010407943
Gene20    0.05905803 -0.0019643847
Gene52    0.02579492 -0.0007652633

$sig.pvalues
            p-value R-squared p.valor_beta0 p.valor_Group.2vsGroup.1
Gene1  8.725223e-42 0.8368073  1.929619e-19                       NA
Gene2  5.481191e-43 0.8589217  3.343108e-17                       NA
Gene3  2.343926e-75 0.9204022  3.400685e-11               0.04338350
Gene4  1.036785e-58 0.8781336  7.187104e-17                       NA
Gene5  5.476285e-32 0.8379997  9.284463e-20                       NA
Gene6  1.041572e-44 0.8440434  5.238118e-22                       NA
Gene7  8.653718e-53 0.8778582  9.321851e-19                       NA
Gene8  9.219630e-69 0.9061423  1.168346e-20                       NA
Gene9  6.812024e-52 0.8722538  2.866095e-18               0.03542128
Gene10 1.118408e-32 0.8238993  8.466370e-06               0.02467319
Gene11 6.642257e-32 0.7537890  3.100360e-37                       NA
Gene12 1.422268e-20 0.6984293  5.020403e-34                       NA
Gene13 1.317673e-22 0.7120882  1.201732e-34                       NA
Gene14 5.784944e-31 0.7869604  1.391566e-34                       NA
Gene15 2.338147e-13 0.6249374  3.841616e-19               0.04257424
Gene16 3.820547e-12 0.5950398  1.133389e-27                       NA
Gene17 5.311523e-19 0.7144371  5.853498e-31                       NA
Gene18 1.261740e-23 0.7612037  6.348770e-28                       NA
Gene19 1.154120e-32 0.7771347  6.081660e-37                       NA
Gene20 1.633013e-27 0.7539848  3.339095e-32               0.01652672
Gene52 2.728287e-03 0.2788091            NA                       NA
       p.valor_Time p.valor_TimexGroup.2 p.valor_Time2
Gene1            NA         1.142500e-07            NA
Gene2            NA         1.096233e-08            NA
Gene3   0.013646113         2.881477e-07   0.002480463
Gene4   0.040946166         2.218442e-10            NA
Gene5            NA         8.484448e-13            NA
Gene6            NA         1.492607e-09            NA
Gene7            NA         2.929700e-10            NA
Gene8            NA         2.453563e-10            NA
Gene9            NA         1.432978e-04            NA
Gene10  0.002047628         5.926159e-03   0.002920182
Gene11           NA                   NA            NA
Gene12           NA                   NA            NA
Gene13           NA                   NA            NA
Gene14           NA         1.069389e-02            NA
Gene15  0.017276544                   NA            NA
Gene16           NA                   NA   0.092193236
Gene17           NA         1.452817e-02            NA
Gene18           NA         5.020853e-02   0.055752096
Gene19           NA                   NA            NA
Gene20           NA         4.207195e-03            NA
Gene52  0.036158348         3.445917e-03   0.064405904
       p.valor_Time2xGroup.2
Gene1           1.935202e-03
Gene2           2.216415e-04
Gene3                     NA
Gene4           1.220671e-04
Gene5                     NA
Gene6           2.289293e-05
Gene7           9.765874e-06
Gene8           5.034579e-05
Gene9           1.495066e-02
Gene10                    NA
Gene11          1.439471e-13
Gene12          5.412554e-11
Gene13          1.338021e-11
Gene14          1.275310e-06
Gene15          6.132105e-08
Gene16          1.423823e-06
Gene17          2.153240e-05
Gene18          3.196422e-05
Gene19          1.160516e-13
Gene20          4.595994e-06
Gene52          3.414695e-03

$g
[1] 21

$edesign
        Time Replicates Group.1 Group.2
G1.T1.1    0          1       1       0
G1.T1.2    0          1       1       0
G1.T1.3    0          1       1       0
G1.T2.1   12          2       1       0
G1.T2.2   12          2       1       0
G1.T2.3   12          2       1       0
G1.T3.1   24          3       1       0
G1.T3.2   24          3       1       0
G1.T3.3   24          3       1       0
G1.T4.1   36          4       1       0
G1.T4.2   36          4       1       0
G1.T4.3   36          4       1       0
G1.T5.1   48          5       1       0
G1.T5.2   48          5       1       0
G1.T5.3   48          5       1       0
G1.T6.1   60          6       1       0
G1.T6.2   60          6       1       0
G1.T6.3   60          6       1       0
G2.T1.1    0          7       0       1
G2.T1.2    0          7       0       1
G2.T1.3    0          7       0       1
G2.T2.1   12          8       0       1
G2.T2.2   12          8       0       1
G2.T2.3   12          8       0       1
G2.T3.1   24          9       0       1
G2.T3.2   24          9       0       1
G2.T3.3   24          9       0       1
G2.T4.1   36         10       0       1
G2.T4.2   36         10       0       1
G2.T4.3   36         10       0       1
G2.T5.1   48         11       0       1
G2.T5.2   48         11       0       1
G2.T5.3   48         11       0       1
G2.T6.1   60         12       0       1
G2.T6.2   60         12       0       1
G2.T6.3   60         12       0       1

$groups.vector
[1] "Group.1"          "Group.2vsGroup.1" "Group.1"         
[4] "Group.2vsGroup.1" "Group.1"          "Group.2vsGroup.1"
# Group into 4 clusters

# see.genes(get_NB_genes$sig.genes, k = 4)

# If we had multiple comparisons (e.g. human, chimpanzee, and rhesus), we could use this function to compare DE genes from different sets of pairwise comparisons

# suma2Venn(get_NB_genes$summary[,c(2:3)])

# Plot the expression values with regression curve
Gene1 <- NBdata[rownames(NBdata) == "Gene1", ]
PlotGroups(Gene1, edesign = NBdesign)

# Add the regression curve computed for this gene to the plot
PlotGroups(Gene1, edesign = NBdesign, show.fit = T, dis = d$dis, groups.vector = d$groups.vector)

Using the endotoxin data

Make the endotoxin data in the same format as the NBdata and NBdesign

# Change endotoxin data at the onset so that controls are listed first and cases are listed second

endotoxin_data <- rbind(endotoxin_data[25:46, ], endotoxin_data[1:24, ])

# Make the expression data matrix

endo_data <- rbind(endotoxin_data[1,-(1:3)], endotoxin_data[7,-(1:3)], endotoxin_data[11,-(1:3)], endotoxin_data[17,-(1:3)], endotoxin_data[2,-(1:3)], endotoxin_data[8,-(1:3)], endotoxin_data[12,-(1:3)], endotoxin_data[18,-(1:3)], endotoxin_data[4,-(1:3)], endotoxin_data[14,-(1:3)], endotoxin_data[20,-(1:3)], endotoxin_data[5,-(1:3)], endotoxin_data[15,-(1:3)], endotoxin_data[21,-(1:3)], endotoxin_data[6,-(1:3)], endotoxin_data[10,-(1:3)], endotoxin_data[16,-(1:3)], endotoxin_data[22,-(1:3)], endotoxin_data[3,-(1:3)], endotoxin_data[9,-(1:3)], endotoxin_data[13,-(1:3)], endotoxin_data[19,-(1:3)], endotoxin_data[23,-(1:3)], endotoxin_data[29,-(1:3)], endotoxin_data[35,-(1:3)], endotoxin_data[41,-(1:3)], endotoxin_data[24,-(1:3)], endotoxin_data[30,-(1:3)], endotoxin_data[36,-(1:3)], endotoxin_data[42,-(1:3)], endotoxin_data[26,-(1:3)], endotoxin_data[32,-(1:3)], endotoxin_data[38,-(1:3)], endotoxin_data[44,-(1:3)], endotoxin_data[27,-(1:3)], endotoxin_data[33,-(1:3)], endotoxin_data[40,-(1:3)], endotoxin_data[45,-(1:3)], endotoxin_data[28,-(1:3)], endotoxin_data[34,-(1:3)], endotoxin_data[41,-(1:3)], endotoxin_data[46,-(1:3)], endotoxin_data[25,-(1:3)], endotoxin_data[31,-(1:3)], endotoxin_data[37,-(1:3)], endotoxin_data[43,-(1:3)])


t_endo_data <- t(endo_data)

rownames(t_endo_data) <- c(1:500)

# Note: missing time points 4 and 6 for individual 6

colnames(t_endo_data) <- c("G1.T1.1", "G1.T2.1", "G1.T6.1", "G1.T3.1","G1.T4.1", "G1.T5.1", "G1.T1.2", "G1.T2.2", "G1.T6.2", "G1.T5.2", "G1.T1.3", "G1.T2.3", "G1.T6.3", "G1.T3.3","G1.T4.3", "G1.T5.3","G1.T1.4", "G1.T2.4", "G1.T6.4", "G1.T3.4","G1.T4.4", "G1.T5.4", "G2.T1.1", "G2.T2.1", "G2.T6.1", "G2.T3.1","G2.T4.1", "G2.T5.1", "G2.T1.2", "G2.T2.2", "G2.T6.2", "G2.T3.2", "G2.T4.2","G2.T5.2", "G2.T1.3", "G2.T2.3", "G2.T6.3", "G2.T3.3","G2.T4.3", "G2.T5.3","G2.T1.4", "G2.T2.4", "G2.T6.4", "G2.T3.4","G2.T4.4", "G2.T5.4")

dim(t_endo_data)
[1] 500  46
head(t_endo_data)
    G1.T1.1   G1.T2.1   G1.T6.1   G1.T3.1   G1.T4.1   G1.T5.1   G1.T1.2
1 10.380374 10.408074 10.419301 10.463046 10.381025 10.466839 10.496759
2 10.426795 10.425668 10.431465 10.380684 10.400377 10.318474 10.392589
3  9.871584  9.897721  9.344084  9.194109  9.683277  9.644846  9.522666
4 10.298262 10.369703 10.223213 10.277187 10.277221 10.337994 10.279661
5 10.662142 10.581800 10.641799 10.585599 10.556568 10.576560 10.667047
6 10.539482 10.622814 10.471043 10.524306 10.597834 10.531749 10.546683
    G1.T2.2   G1.T6.2   G1.T5.2   G1.T1.3   G1.T2.3   G1.T6.3   G1.T3.3
1 10.554953 10.456970 10.480241 10.421299 10.399189 10.523338 10.533988
2 10.468801 10.436231 10.388380 10.426825 10.316722 10.377514 10.520698
3  9.540076  9.777754  9.357984  9.391077  9.677904  9.494466  9.660078
4 10.443396 10.389979 10.289532 10.342484 10.391822 10.353607 10.331073
5  3.218876 10.607451 10.677685 10.602865 10.598059 10.675076 10.437522
6 10.532176 10.554666 10.494464 10.510668 10.506683 10.508268 10.554171
    G1.T4.3   G1.T5.3   G1.T1.4   G1.T2.4   G1.T6.4   G1.T3.4   G1.T4.4
1 10.361419 10.440478 10.486680 10.493411 10.398336 10.324399 10.372147
2 10.389826 10.331431 10.374772 10.443076 10.413493 10.242528 10.453572
3  9.698859  9.655731  9.362718  9.257701  9.808902  9.566475  9.511333
4 10.437346 10.236776 10.227200 10.468659 10.249945 10.173324 10.231207
5 10.605347 10.658365 10.680286  6.455199 10.596810 10.584081 10.633256
6 10.554849 10.547970 10.537389 10.506901 10.521399 10.492773 10.495377
   G1.T5.4   G2.T1.1   G2.T2.1   G2.T6.1   G2.T3.1   G2.T4.1   G2.T5.1
1 10.41547 10.592501 10.578420 10.525004 10.523661  7.771067 10.576993
2 10.43811 10.453630 10.561966 10.461388 10.524897 10.540805 10.663101
3  9.46916  9.521861  9.718302  9.611998  9.485165  9.305923  9.665865
4 10.31907 10.124108 10.221323 10.308086 10.175954 10.362430 10.250829
5 10.61893 10.592978 10.585902 10.627067 10.493078 10.678030 10.636600
6 10.54395 10.524978 10.599979 10.625198 10.559037 10.551847 10.613271
    G2.T1.2  G2.T2.2   G2.T6.2   G2.T3.2   G2.T4.2   G2.T5.2   G2.T1.3
1 10.467977 10.60597 10.599929 10.619741 10.511567 10.583853 10.533349
2 10.588628 10.57613 10.596085 10.426024 10.526802 10.525729 10.592501
3  9.645882  9.52712  9.648079  9.208739  9.441135  9.396737  9.737374
4 10.305848 10.32351 10.642014 10.608341 10.549307 10.621620 10.587241
5 10.643041 10.63809 10.681573 10.648919 10.674452 10.643256 10.625441
6 10.632894 10.59064 10.598807 10.538555 10.646282 10.608020 10.597409
    G2.T2.3  G2.T6.3   G2.T3.3   G2.T4.3   G2.T5.3   G2.T1.4   G2.T2.4
1 10.600203 10.47858 10.553571 10.592777 10.597734 10.523661 10.561008
2 10.583271 10.51401 10.381738 10.571650 10.502159 10.524897 10.524360
3  9.468388  9.45548  9.367259  9.591513  9.460398  9.485165  9.351753
4 10.650578 10.54115 10.647257 10.574133 10.561655 10.175954 10.503066
5 10.611400 10.66045 10.681229 10.642229 10.633232 10.493078 10.640005
6 10.581927 10.62333 10.577121 10.652282 10.583043 10.559037 10.558102
    G2.T6.4   G2.T3.4   G2.T4.4   G2.T5.4
1  6.606650 10.623739 10.405837 10.490885
2 10.494131 10.470391 10.492079 10.451725
3  9.657011  9.418005  9.640368  9.691964
4 10.291162 10.323743 10.322560 10.274327
5 10.623666 10.638880 10.628787 10.657753
6 10.590893 10.595234 10.582967 10.590793
# Make a matrix that contains the information that will be used in a design matrix.
# Note: for some weird reason, you need time to be the first (leftmost) column

endo_design1 <- c(0,0,0,0,2,2,2,2,4,4,4,6,6,6,9,9,9,9,24,24,24,24,0,0,0,0,2,2,2,2,4,4,4,4,6,6,6,6,9,9,9,9,24,24,24,24)

#endo_design2 <- c(1,2,3,4,1,2,3,4,1,3,4,1,3,4,1,2,3,4,1,2,3,4, 5,6,7,8,5,6,7,8,5,6,7,8,5,6,7,8,5,6,7,8,5,6,7,8)

endo_design2 <- c(1,1,1,1,2,2,2,2,3,3,3,4,4,4,5,5,5,5,6,6,6,6,7,7,7,7,8,8,8,8,9,9,9,9,10,10,10,10,11,11,11,11,12,12,12,12)

#endo_design1 <- array(1:46, dim = c(46,1))
#endo_design2 <- endotoxin_data[,2]
endo_design <- cbind(endo_design1, endo_design2)

# Make two columns, one for Group.1 (cases but it could be something like chimps) and Group.2 (controls but it could be something like humans)

# Group 1 (controls)
group10 <- array(1, dim = c(1,22))
group11 <- array(0, dim = c(1,24))
group1 <- cbind(group10, group11)

# Group 2 (cases)
group20 <- array(0, dim = c(1,22))
group21 <- array(1, dim = c(1,24))
group2 <- cbind(group20, group21)

group12 <- rbind(group1, group2)
t_group12 <- t(group12)

final_endo_design <- cbind(endo_design, t_group12)

colnames(final_endo_design) <- c("Time", "Replicate", "Group.1", "Group.2")

rownames(final_endo_design) <- c("G1.T1.1", "G1.T2.1", "G1.T6.1", "G1.T3.1","G1.T4.1", "G1.T5.1", "G1.T1.2", "G1.T2.2", "G1.T6.2", "G1.T5.2", "G1.T1.3", "G1.T2.3", "G1.T6.3", "G1.T3.3","G1.T4.3", "G1.T5.3","G1.T1.4", "G1.T2.4", "G1.T6.4", "G1.T3.4","G1.T4.4", "G1.T5.4", "G2.T1.1", "G2.T2.1", "G2.T6.1", "G2.T3.1","G2.T4.1", "G2.T5.1", "G2.T1.2", "G2.T2.2", "G2.T6.2", "G2.T3.2", "G2.T4.2","G2.T5.2", "G2.T1.3", "G2.T2.3", "G2.T6.3", "G2.T3.3","G2.T4.3", "G2.T5.3","G2.T1.4", "G2.T2.4", "G2.T6.4", "G2.T3.4","G2.T4.4", "G2.T5.4")
#colnames(t_endo_data) <- rownames(final_endo_design)

Make design matrix using maSigPro commands

# Make a design matrix of values. It will generate values for different values of time and the interaction of time and group (0 iif control and time^n*1 iif case). The default here is to make df = 2; however, since we have 6 time points, we could go up to degree = 5 (# of time points - 1, as discussed in the maSigPro User's Guide page 5)

matrix_endo_design <- make.design.matrix(final_endo_design, degree = 5)
#rownames(matrix_endo_design$edesign) <- c("G1.T1.1", "G1.T2.1", "G1.T6.1", "G1.T3.1","G1.T4.1", "G1.T5.1", "G1.T1.2", "G1.T2.2", "G1.T6.2", "G1.T5.2", "G1.T1.3", "G1.T2.3", "G1.T6.3", "G1.T3.3","G1.T4.3", "G1.T5.3","G1.T1.4", "G1.T2.4", "G1.T6.4", "G1.T3.4","G1.T4.4", "G1.T5.4", "G2.T1.1", "G2.T2.1", "G2.T6.1", "G2.T3.1","G2.T4.1", "G2.T5.1", "G2.T1.2", "G2.T2.2", "G2.T6.2", "G2.T3.2", "G2.T4.2","G2.T5.2", "G2.T1.3", "G2.T2.3", "G2.T6.3", "G2.T3.3","G2.T4.3", "G2.T5.3","G2.T1.4", "G2.T2.4", "G2.T6.4", "G2.T3.4","G2.T4.4", "G2.T5.4")
# Look at the design matrix

head(matrix_endo_design$dis)
        Group.2vsGroup.1 Time TimexGroup.2 Time2 Time2xGroup.2 Time3
G1.T1.1                0    0            0     0             0     0
G1.T2.1                0    0            0     0             0     0
G1.T6.1                0    0            0     0             0     0
G1.T3.1                0    0            0     0             0     0
G1.T4.1                0    2            0     4             0     8
G1.T5.1                0    2            0     4             0     8
        Time3xGroup.2 Time4 Time4xGroup.2 Time5 Time5xGroup.2
G1.T1.1             0     0             0     0             0
G1.T2.1             0     0             0     0             0
G1.T6.1             0     0             0     0             0
G1.T3.1             0     0             0     0             0
G1.T4.1             0    16             0    32             0
G1.T5.1             0    16             0    32             0
head(matrix_endo_design$edesign)
        Time Replicate Group.1 Group.2
G1.T1.1    0         1       1       0
G1.T2.1    0         1       1       0
G1.T6.1    0         1       1       0
G1.T3.1    0         1       1       0
G1.T4.1    2         2       1       0
G1.T5.1    2         2       1       0
  # This generates a matrix with the headers of Group.2vsGroup.1, Time, Time*Group.2 (Group.2 = 1 iif a case), Time^2, Time^2xGroup.2, etc. 

# Look at the assignment of regression variables to experimental groups. The output matches the format of the examples in the maSigPro User's Guide. 

matrix_endo_design$groups.vector
 [1] "Group.2vsGroup.1" "Group.1"          "Group.2vsGroup.1"
 [4] "Group.1"          "Group.2vsGroup.1" "Group.1"         
 [7] "Group.2vsGroup.1" "Group.1"          "Group.2vsGroup.1"
[10] "Group.1"          "Group.2vsGroup.1"

Find significant genes

This step identifies the significant genes by computing a regression fit for each gene and also the p-value associated with the F-statistic of the model. We can then set our threshold for significant genes.

# Exercise step 1 of the two-step regression procedure

# We are using theta = 10. We can check if this is close to the actual value by using edgeR; however, the results 

# Compute a regression fit for each gene. Comupte a p-value associated with the F-statistic of the model (FDR = 10%). Note, it fits regression models for each gene but in "batches" of 100 genes. 

endo_p_vector <- p.vector(t_endo_data, 
                          matrix_endo_design, 
                          counts = TRUE, theta = 10, Q = 0.10, MT.adjust = "BH")
[1] "fitting gene 100 out of 500"
[1] "fitting gene 200 out of 500"
[1] "fitting gene 300 out of 500"
[1] "fitting gene 400 out of 500"
[1] "fitting gene 500 out of 500"
# Save unadjusted p-values for comparison
head(endo_p_vector$p.vector)
       p.value
1 6.851479e-01
2 2.313605e-07
3 9.432892e-01
4 2.062499e-16
5 6.989420e-01
6 2.314428e-04
# svae output if output has not been saved already
if (!file.exists("../data/p_value_maSigPro_df_5.txt")) {
write.table(endo_p_vector$p.vector, 
            "../data/p_value_maSigPro_df_5.txt", sep="\t")
}


# Find the number of significant genes at FDR 10%

endo_p_vector$i
[1] 198
# Find the p-value (of the F statistic of the model) at the 10% false discovery control level

head(endo_p_vector$p.adjusted)
[1] 8.292585e-01 2.570673e-06 9.753216e-01 4.910712e-15 8.380600e-01
[6] 1.205431e-03
# Make a vector of the adjusted p-values so that we can compare them

p_value_endo_genes_masigpro <- as.data.frame(endo_p_vector$p.adjusted)
rownames(p_value_endo_genes_masigpro) <- c(1:500)

# A matrix with the significant genes and their expression values

head(endo_p_vector$SELEC)
     G1.T1.1   G1.T2.1   G1.T6.1   G1.T3.1   G1.T4.1   G1.T5.1   G1.T1.2
2  10.426795 10.425668 10.431465 10.380684 10.400377 10.318474 10.392589
4  10.298262 10.369703 10.223213 10.277187 10.277221 10.337994 10.279661
6  10.539482 10.622814 10.471043 10.524306 10.597834 10.531749 10.546683
7  10.462789 10.343998 10.324990 10.253827 10.388411 10.376206 10.085892
8   9.988518  9.945109  9.895405  9.853457  9.971380  9.911852  9.621721
12  8.412277  8.675222  9.166179  8.765615  8.565031  8.686261  8.712595
     G1.T2.2   G1.T6.2   G1.T5.2   G1.T1.3   G1.T2.3   G1.T6.3   G1.T3.3
2  10.468801 10.436231 10.388380 10.426825 10.316722 10.377514 10.520698
4  10.443396 10.389979 10.289532 10.342484 10.391822 10.353607 10.331073
6  10.532176 10.554666 10.494464 10.510668 10.506683 10.508268 10.554171
7  10.295800 10.414093 10.333255 10.187576 10.386130 10.347243 10.141086
8   9.555560 10.018199  9.648402  9.829410  9.975994  9.479375  9.781885
12  9.051227  8.561975  9.026538  8.972083  8.241176  8.850374  8.583355
     G1.T4.3   G1.T5.3   G1.T1.4   G1.T2.4   G1.T6.4   G1.T3.4   G1.T4.4
2  10.389826 10.331431 10.374772 10.443076 10.413493 10.242528 10.453572
4  10.437346 10.236776 10.227200 10.468659 10.249945 10.173324 10.231207
6  10.554849 10.547970 10.537389 10.506901 10.521399 10.492773 10.495377
7  10.355868 10.491885 10.324859 10.332409 10.389734 10.302499 10.290619
8  10.007532  9.942516  9.832475  9.769327 10.012252  9.879758  9.848345
12  8.173293  7.968666  9.089302  8.987322  8.377931  8.240121  8.891787
     G1.T5.4   G2.T1.1   G2.T2.1   G2.T6.1   G2.T3.1   G2.T4.1   G2.T5.1
2  10.438108 10.453630 10.561966 10.461388 10.524897 10.540805 10.663101
4  10.319068 10.124108 10.221323 10.308086 10.175954 10.362430 10.250829
6  10.543946 10.524978 10.599979 10.625198 10.559037 10.551847 10.613271
7  10.235055 10.412051 10.414153 10.347725 10.277462 10.583043 10.526909
8   9.952325  9.640693  9.760887  9.778888  9.642967 10.107978  9.426661
12  8.510571  8.905580  8.506334  7.983440  7.445418  8.739536  8.534050
     G2.T1.2   G2.T2.2   G2.T6.2   G2.T3.2   G2.T4.2   G2.T5.2   G2.T1.3
2  10.588628 10.576126 10.596085 10.426024 10.526802 10.525729 10.592501
4  10.305848 10.323513 10.642014 10.608341 10.549307 10.621620 10.587241
6  10.632894 10.590642 10.598807 10.538555 10.646282 10.608020 10.597409
7  10.405050 10.590742 10.460729 10.553675 10.409944 10.470646 10.405081
8   9.524494  9.607370  9.099185  9.236593  9.607034  9.493788  9.463276
12  8.042056  8.073403  8.512984  7.397562  8.337349  8.058327  8.274102
     G2.T2.3   G2.T6.3   G2.T3.3   G2.T4.3   G2.T5.3   G2.T1.4   G2.T2.4
2  10.583271 10.514014 10.381738 10.571650 10.502159 10.524897 10.524360
4  10.650578 10.541148 10.647257 10.574133 10.561655 10.175954 10.503066
6  10.581927 10.623325 10.577121 10.652282 10.583043 10.559037 10.558102
7  10.491274 10.394090 10.387795 10.456827 10.445318 10.277462 10.486234
8   9.478228  9.639457  9.644652  9.618070  9.798738  9.642967  9.521055
12  8.220672  7.769801  6.318968  8.473659  7.483807  7.445418  6.722630
     G2.T6.4   G2.T3.4   G2.T4.4   G2.T5.4
2  10.494131 10.470391 10.492079 10.451725
4  10.291162 10.323743 10.322560 10.274327
6  10.590893 10.595234 10.582967 10.590793
7  10.422847 10.480775 10.444328 10.334425
8   9.849137  9.944965  9.790935  9.924662
12  8.607582  8.875287  8.495970  8.160232

Find the significant coefficients for the significant genes (stepwise regression)

The significant genes were identified in the previous section. We can now apply a variable selection procedure to find the significant variables for each gene. This can mean that there is a different number of significant coefficients and therefore a different model for each gene. The author’s highlight the flexibility of the method in their paper introducing this package.

# Execute the stepwise (forward) regression. At each regression step, the p-value of each variable is computed and variables get in/out when the p-value is lower/higher than the given cutoff (alfa). 

endo_t_stat <- T.fit(endo_p_vector)
[1] "fitting gene 100 out of 198"
[1] "Influence: 15 genes with influential data at slot influ.info. Model validation for these genes is recommended"
# p-value of the regression ANOVA, R-squared of the model, and p-value of the regression coefficients of the selected variables

head(endo_t_stat$sol)
        p-value R-squared p.valor_beta0 p.valor_Group.2vsGroup.1
2  1.087306e-10 0.5802967 6.583567e-101             2.398572e-03
4  1.132691e-18 0.7003170  3.952766e-92             4.081439e-03
6  1.909168e-09 0.4505929 2.384086e-121             3.314073e-07
7  2.606482e-05 0.4644825  1.057008e-82                       NA
8  2.033452e-07 0.4730113  6.395827e-85                       NA
12 6.710574e-07 0.4223760  3.985691e-62             4.447240e-02
   p.valor_Time p.valor_TimexGroup.2 p.valor_Time2 p.valor_Time2xGroup.2
2            NA         0.0538967622            NA          5.365737e-02
4            NA                   NA    0.07691589          1.986053e-09
6            NA                   NA            NA                    NA
7    0.08888829         0.0002280788    0.07354823          4.457123e-03
8            NA                   NA            NA          1.174827e-03
12           NA                   NA            NA          4.648324e-03
   p.valor_Time3 p.valor_Time3xGroup.2 p.valor_Time4 p.valor_Time4xGroup.2
2             NA          6.199302e-02            NA          6.683695e-02
4             NA          9.605137e-09            NA          1.982848e-08
6             NA                    NA            NA                    NA
7     0.07078373          1.971314e-02            NA          3.600823e-02
8             NA          6.839609e-03            NA          1.664070e-02
12            NA          3.012210e-03            NA                    NA
   p.valor_Time5 p.valor_Time5xGroup.2
2             NA                    NA
4             NA                    NA
6             NA                    NA
7             NA                    NA
8             NA            0.02416148
12            NA                    NA
# Obtaining lists of significant genes for each experimental group. We can set and R-squared value so that the models must be greater than 0.2.

endo_sig_genes <- get.siggenes(endo_t_stat, rsq = 0.2, var = "groups")

# Get the lists of significant genes

  # The first list (Group.1) contains genes whose expression is significantly different from a 0 profile in the reference group. 
  # The second list (Group.2vsGroup.1) contains differentially expressed curves.  We are most interested in the second list because it contains genes whose profiles for the experimental group is different from the reference group. 

names(endo_sig_genes$sig.genes)
[1] "Group.1"          "Group.2vsGroup.1"
endo_sig_genes$summary
    Group.1 Group.2vsGroup.1
1         4                2
2         7                4
3        19                6
4        26                7
5        33                8
6        36               12
7        37               19
8        41               21
9        45               22
10       51               26
11       64               29
12       80               30
13       87               33
14       91               36
15      106               37
16      109               39
17      113               41
18      114               44
19      125               45
20      138               51
21      139               53
22      165               56
23      167               58
24      178               59
25      188               62
26      189               63
27      191               64
28      205               68
29      223               73
30      230               74
31      246               76
32      250               80
33      257               82
34      262               84
35      265               87
36      278               91
37      302               96
38      312               97
39      315              101
40      326              103
41      329              106
42      332              107
43      335              108
44      337              109
45      354              113
46      358              114
47      363              117
48      365              119
49      366              123
50      372              125
51      380              128
52      384              130
53      388              133
54      394              138
55      413              139
56      422              141
57      426              144
58      427              153
59      441              154
60      447              157
61      454              161
62      459              165
63      462              167
64      468              168
65      469              170
66      482              174
67      500              176
68                       178
69                       182
70                       183
71                       184
72                       185
73                       187
74                       188
75                       189
76                       190
77                       191
78                       192
79                       193
80                       196
81                       200
82                       204
83                       205
84                       207
85                       208
86                       211
87                       216
88                       222
89                       223
90                       224
91                       226
92                       229
93                       230
94                       233
95                       234
96                       236
97                       246
98                       248
99                       249
100                      250
101                      251
102                      253
103                      256
104                      257
105                      261
106                      262
107                      265
108                      269
109                      270
110                      272
111                      274
112                      277
113                      278
114                      280
115                      283
116                      285
117                      288
118                      295
119                      302
120                      306
121                      308
122                      310
123                      311
124                      312
125                      315
126                      317
127                      320
128                      325
129                      326
130                      329
131                      331
132                      332
133                      335
134                      337
135                      339
136                      343
137                      348
138                      353
139                      354
140                      355
141                      358
142                      363
143                      364
144                      365
145                      366
146                      372
147                      375
148                      376
149                      380
150                      381
151                      382
152                      384
153                      385
154                      387
155                      388
156                      391
157                      394
158                      399
159                      401
160                      413
161                      416
162                      420
163                      422
164                      426
165                      427
166                      430
167                      431
168                      437
169                      439
170                      441
171                      445
172                      446
173                      447
174                      450
175                      451
176                      454
177                      456
178                      457
179                      459
180                      460
181                      462
182                      463
183                      466
184                      468
185                      469
186                      475
187                      476
188                      477
189                      478
190                      479
191                      482
192                      484
193                      486
194                      489
195                      492
196                      499
197                      500
head(endo_sig_genes$sig.genes$Group.2vsGroup.1)
$sig.profiles
      G1.T1.1   G1.T2.1   G1.T6.1   G1.T3.1   G1.T4.1   G1.T5.1   G1.T1.2
2   10.426795 10.425668 10.431465 10.380684 10.400377 10.318474 10.392589
4   10.298262 10.369703 10.223213 10.277187 10.277221 10.337994 10.279661
6   10.539482 10.622814 10.471043 10.524306 10.597834 10.531749 10.546683
7   10.462789 10.343998 10.324990 10.253827 10.388411 10.376206 10.085892
8    9.988518  9.945109  9.895405  9.853457  9.971380  9.911852  9.621721
12   8.412277  8.675222  9.166179  8.765615  8.565031  8.686261  8.712595
19   8.291296  7.982416  7.588324  8.093768  8.568266  8.379309  7.473637
21  10.374616 10.453082 10.524628 10.476104 10.342258 10.456079 10.484417
22   9.974598  9.953943  9.888831  9.746307  9.924515  9.930227  9.778264
26   9.731690  9.760714  9.583007  9.837508  9.721066  9.684398  9.724480
29  10.552448 10.511703 10.536725 10.495073 10.574900 10.454409 10.627818
30  10.386592 10.278803 10.626533 10.630287 10.345799 10.414123 10.499160
33  10.632822 10.600751 10.577987 10.572624 10.571009 10.577223 10.516915
36  10.642373 10.678514  9.410420  8.600983 10.635495 10.680263  8.945724
37   9.319643  9.328657  9.448570  9.502338  9.472166  9.469469  9.533076
39   9.175128  9.279960  9.503010  9.420277  9.120634  9.211340  9.665103
41   8.588397  8.373323  8.726157  8.894944  8.671972  8.645586  8.743532
44   9.589325  9.599405  9.825039  9.777981  9.691964  9.728181  9.823362
45  10.043771  9.975110  9.778718  9.868741  9.995246  9.878067  9.949273
51  10.269102 10.242813 10.455877 10.125551 10.365144 10.392865 10.401471
53  10.422341 10.342645 10.057110 10.245906 10.398854 10.440712 10.151129
56   9.108751  9.100079  9.369052  9.657715  9.017968  9.258750  9.147507
58  10.085642 10.191482 10.308319 10.308553 10.135710  9.937599 10.385451
59   9.475240  9.481207 10.009917  9.806591  9.483645  9.528285  9.879605
62   9.095154  8.807621  9.013839  8.839277  9.045937  8.849084  8.874588
63  10.031749 10.051864 10.126031 10.129308 10.136225 10.067008 10.080168
64  10.115651 10.060320 10.289838 10.161689 10.230126 10.226404 10.276223
68  10.500729 10.340128 10.365428 10.234768 10.411569 10.341484 10.317086
73   7.428333  7.027315  8.782476  7.963460  7.374002  7.446585  8.367765
74  10.529640 10.285991 10.551480 10.570470 10.455705 10.475004 10.407289
76  10.009018 10.190244  9.628063  9.805323 10.064926 10.057024  9.818311
80   8.405591 10.672808 10.517240 10.585043  7.450661 10.587871 10.648587
82  10.061815 10.232539 10.270558 10.015431 10.111639 10.217897 10.293907
84  10.633569 10.560230 10.607698  5.808142 10.630263 10.674406 10.584309
87   9.345745  9.528285  9.307376  8.639234  9.190648  9.493638  9.037296
91   9.768698  9.535824  9.688312  9.548026  9.532859  9.517752  9.377041
96  10.246616 10.207141 10.505971 10.453890 10.167773 10.120009 10.374491
97  10.232647 10.222269 10.449671 10.231387 10.288682 10.313509 10.433027
101  9.159889  9.177404  8.544419  9.178024  8.944550  8.761550  8.965718
103 10.373054 10.475935 10.279077 10.132613 10.393416 10.415023 10.329703
106  7.168580 10.673573 10.661767 10.623715  7.874359  8.048149 10.674221
107 10.085309 10.264618  9.988656  9.879912 10.128509 10.172713 10.079330
108  9.666499  9.513256  9.974831  9.818311  9.901636  9.811537  9.938758
109  9.185945  9.050876  9.177301  9.069813  8.940367  8.911260  9.125327
113 10.489105 10.541571 10.491108 10.501774 10.519943 10.545289 10.526293
114  7.500529  7.114769  9.058121  8.956222 10.663990 10.679228  8.705662
117  8.539150  9.333531  8.941022  8.332789  8.982059  8.668368  9.144094
119 10.689146 10.664947  8.987822  9.484481 10.675792 10.284353  8.998137
123  7.745436  8.509766  8.153350  8.169620  6.180017  7.551712 10.679113
125 10.042684 10.149996 10.212405  9.590283 10.048540 10.082052 10.210715
128  9.710873  9.770585  9.984560  9.996340  9.656947  9.895959 10.088181
130 10.490580 10.564680 10.415622 10.351214 10.519916 10.579082 10.492995
133  9.071653  8.708309  9.671051  9.389741  9.234838  9.149422  9.258654
138 10.319365 10.329768 10.237886 10.249910 10.292857 10.356504 10.146002
139 10.444066 10.304108 10.324170 10.176487 10.327545 10.351948 10.201479
141  9.769156  9.860162  9.917883  9.866927  9.580316  9.714685  9.819617
144 10.063308  9.951420  9.905386  9.865526  9.950276  9.999979  9.849559
153  7.407318  6.739337  8.173293  8.063378  6.558198  6.907755  7.828436
154  9.976134  9.928424 10.117550 10.091791 10.115449 10.167773 10.118276
157  9.464130  9.512369  9.824174  9.839056  9.613469  9.591991  9.716194
161 10.602691 10.486569 10.625149 10.544367 10.519457 10.570676 10.468233
165  9.456810  9.761233  9.536618  8.976009  9.660843  9.731987  9.216024
167 10.623739  8.514189  9.492960 10.676993  7.494430  6.220590  9.166911
168 10.373272 10.224556 10.359551 10.435145 10.345156 10.389395 10.277943
170 10.629271 10.663008 10.552448 10.613271 10.637777 10.621498 10.545157
174 10.296306 10.427387 10.425757 10.327709 10.254813 10.457286 10.292993
176 10.226259 10.059380 10.227670 10.201553 10.024731 10.053329 10.252065
178  8.142936  8.303009  8.097122  8.115521  8.326517  8.141190  8.550241
182  9.710388  9.919853  9.349406  9.686450  9.914230  9.834245  9.293026
183  9.762327  9.565775  9.806701  9.638545  9.950848  9.506214  9.753827
184 10.576228 10.630045 10.617417 10.590114 10.562069 10.619667 10.585801
185  9.220588  9.407304  9.614338  9.913933  9.305651  9.687568  9.603530
187  9.384630  9.635543  9.647240  9.546098  9.509482  9.617071  9.561912
188  9.230143  9.620793  9.174402  9.387063  9.463509  9.654128  9.260748
189  9.584934  9.685642  9.535679  9.664596  9.639587  9.583558  9.368967
190 10.051131 10.245054  9.915169 10.015565 10.036969 10.110095 10.033067
191  9.886545  9.682654  9.746073  9.683962  9.750453  9.623906  9.510963
192  9.933580  9.937937 10.635062 10.571855  9.775995 10.052942 10.643494
193  9.323937  9.504576  9.615405  9.538060  9.111955  9.520469  8.962392
196 10.142977  9.966791 10.424986 10.437903 10.184183 10.285479 10.274120
200  9.419709  9.030496  8.981933  9.339349  9.518046  9.181426  8.832150
204 10.320486 10.342710 10.308419 10.448077 10.212589 10.298902 10.304409
205 10.603511 10.502516 10.481617 10.515506 10.612164 10.593354 10.578624
207  9.058936  9.154933  9.381517  9.632597  8.832004  9.108640  9.212937
208  9.264165  9.465370  8.805225  9.234252  9.184202  9.139596  9.140025
211 10.533295 10.462360 10.566923 10.515099 10.421537 10.215374 10.395314
216  9.865890  9.974365 10.061858 10.028974  9.817875  9.988518  9.977621
222 10.507175 10.622863 10.619228 10.610562 10.519241 10.527981 10.560800
223 10.568338 10.541096 10.432025 10.431554 10.484473 10.559115 10.449236
224 10.208506 10.278012 10.379846 10.325941 10.248813 10.278459 10.243489
226 10.547471 10.538343 10.592175 10.639670 10.482374 10.578853 10.457976
229  9.452816  9.431402  9.406894  9.193398  9.525005  9.611797  9.377717
230  9.959159 10.070653  9.898676 10.052769  9.672186  9.860789  9.738967
233 10.051692 10.286605 10.150074  9.980911 10.318903 10.174621 10.155257
234  9.960907 10.201664 10.036312  9.862666 10.040332 10.121659  9.995930
236  9.558529  9.603058  8.812248  9.574011  9.430279  9.289521  9.039789
246 10.380281 10.431731 10.417747 10.438079 10.359361 10.365994 10.416161
248  9.802949 10.103895 10.080252  9.741439  9.844427  9.716435 10.150074
249 10.352714 10.335238 10.374491 10.128549 10.328167 10.365112 10.306650
250  9.445808  9.296335  9.458294  9.410584  9.522227  9.478993  9.480138
251  7.865955  7.974877  8.361241  7.404279  7.681099  8.606302  7.356918
253 10.382048 10.377390 10.319167 10.386716 10.404960 10.348910 10.390686
256  9.850930  9.466300  9.592878  9.472551  9.770756  9.614271  9.328568
257 10.374678 10.383596 10.296036 10.255798 10.352236 10.320486 10.311150
261 10.480634 10.241601 10.487406 10.399159 10.412171 10.483690 10.439396
262  9.028699  8.669914  8.871084  9.152817  8.928375  8.634265  8.734238
265 10.243738 10.127471 10.266810 10.405807 10.118115 10.207805 10.234696
269 10.486485 10.569084 10.526105 10.542522 10.495239 10.480213 10.522719
270  9.812797  9.574497  9.988518  9.816349  9.885171  9.805323 10.009108
272 10.208653 10.212001 10.069553 10.218043 10.243205 10.187312 10.046418
274  9.548882  9.144521  9.611530  9.536690  9.516722  9.036106  9.250138
277 10.561603 10.420643 10.628932 10.633160 10.554301 10.496124 10.619838
278 10.346473 10.328723 10.380125 10.302264 10.261232 10.357171 10.354149
280  9.740204  9.824228  9.950657  9.585140  9.845329  9.821952  9.892427
283 10.120935  9.884305 10.381521 10.345670 10.447438 10.020693 10.258676
285 10.217897 10.133329 10.244627 10.310818 10.140179 10.236669 10.299340
288 10.503395 10.498057 10.557816 10.497422 10.483634 10.422847 10.496317
295  8.856946  8.402231  9.421735  9.120963  8.460411  8.182559  9.021115
302  9.827470  9.577273  9.713053  9.482883  9.658418  9.835744  9.813399
306  9.555489  9.619731  9.972920  9.926862  9.746015  9.542015  9.820649
308 10.094604  9.616139 10.212882 10.025440 10.040419  9.781320 10.188328
310  9.400713  9.152817  9.699718  9.737433  9.463586  9.623311  9.445966
311 10.149253 10.074200  9.930762  9.899981 10.110461 10.188065  9.970913
312  7.963112  8.736329 10.640699  8.509766  7.990577  8.196437 10.682721
315 10.186031 10.306416 10.239174 10.370424 10.137096 10.152065 10.215740
317 10.385728 10.269172 10.441529 10.455820 10.397543 10.403020 10.417359
320 10.540276 10.583676 10.658224  7.760467 10.552160 10.620400 10.671487
325  9.116579  9.765145  9.053570  8.874868  9.541872  9.304650  9.098850
326 10.524387 10.461244 10.477485 10.430846 10.461617 10.399189 10.377857
329  8.974745  8.953123  9.852826  9.807857  8.799511  8.313362  9.766350
331 10.432291 10.483354 10.441705 10.492773 10.439308 10.430374 10.488938
332 10.139784 10.226549 10.141677 10.143685  9.901686  9.985390 10.008028
335 10.073315 10.235880 10.149527 10.319728 10.314305 10.102051 10.240745
337 10.411750  9.922751 10.278597  9.705402 10.365112 10.412832 10.237600
339 10.263327 10.217933 10.387671 10.360279 10.218408 10.227128 10.172713
343 10.137611 10.173973 10.091501  9.813070 10.198356 10.111193 10.144039
348  8.456806  7.888710  8.710290  8.916506  8.539346  8.772920  8.764522
353  9.659057  9.583007  9.791270  9.947648  9.774972  9.672816  9.935228
354  9.787291  9.886901  9.773322  9.684025  9.852300  9.989757  9.787964
355 10.406563 10.366026  9.616805  8.880864 10.385852 10.463475  8.987322
358 10.323644 10.344095 10.308986 10.124108 10.381614 10.334750 10.282335
363  9.700453  9.572271  9.808627  9.791382  9.794175  9.733766 10.015163
364  8.935245  9.069583  9.324383  8.615227  9.025576  9.175128  9.000113
365  9.041922  9.168789  9.052516  8.865735  9.095603  9.093132  9.352447
366  7.602900  4.595120  7.865572  5.342334  8.409608  7.800163  8.028455
372 10.168924 10.286127 10.318111 10.331105 10.173629 10.162809 10.311350
375  9.460866  9.470626  9.855557  9.716495  9.455950  9.569203  9.571296
376  7.401842  7.686621  7.173958  7.730175  7.537963  7.982416  7.685703
380 10.359044 10.304409 10.379939 10.324432 10.310085 10.351182 10.357648
381 10.137175 10.336179 10.211891 10.370675 10.284967 10.144157 10.211597
382 10.128589 10.197686 10.158246 10.085476 10.216252 10.110461 10.228863
384  8.357494  8.987072  8.759512  8.241967  8.978787  9.176266  8.810907
385  9.841293 10.252241 10.132375 10.137650 10.041160 10.159485 10.029195
387 10.199658 10.251571 10.486569 10.475117 10.256852 10.296441 10.399677
388  8.736650  8.208764  8.669227  8.606485  8.058011  8.157084  8.458716
391  9.855977  9.667005 10.039198  9.782506  9.649627  9.806316  9.836974
394  9.084664  9.101195  9.148252  9.170351  9.304104  9.205730  9.277158
399  9.405496  9.139059 10.168042  9.902487  8.812248  8.925454  9.871429
401 10.117833  9.889186 10.311848 10.324695 10.114842  9.978038 10.209906
413  7.808323  8.052933  8.489205  8.439448 10.677708  6.052089  7.266827
416 10.554275  8.783396 10.589736 10.536646 10.636000  6.746412 10.590994
420 10.159098 10.126711 10.315167 10.240924 10.297521 10.245729 10.383101
422  9.524494  9.777641  9.617803  9.762903  9.634169  9.653743  9.760367
426  8.615771  7.685244  8.217439  8.466742  8.208764  7.638198  8.410053
427  8.085487  8.197814  8.394800  8.547528  7.829630  7.982075  8.064322
430  9.027259  9.159889  9.446755  9.612467  9.425774  9.261604  9.429235
431 10.350414 10.373866 10.358441 10.406019 10.357489 10.372960 10.472856
437 10.443046 10.523177 10.549936 10.556698 10.446916 10.438723 10.478780
439 10.402443 10.361608 10.376954 10.454841 10.385759 10.397940 10.376705
441 10.154324 10.301424 10.138006 10.058352 10.143213 10.280965  9.972874
445 10.198021 10.324137 10.535132 10.348654 10.250511 10.200216 10.424273
446 10.304744 10.218554 10.468602 10.358822 10.280965 10.349263 10.450597
447 10.690034 10.647304  8.522976  7.625107  6.434547  7.904335  4.499810
450  9.826876  9.725736  9.760425  9.414586  9.789647  9.727466  9.719625
451  9.992002  9.971940 10.367882 10.130264 10.007848 10.059080 10.132732
454 10.211744 10.017129 10.215301 10.022958 10.380653 10.290789 10.022115
456  9.950419  9.721126  9.684709  9.690789  9.802893  9.895052  9.680844
457 10.364261 10.385204 10.477344 10.454466 10.402989 10.404929 10.402382
459 10.283156 10.300618 10.189230 10.202517 10.218700 10.320980 10.106306
460 10.450973 10.310252 10.589912 10.659516 10.428039 10.525380 10.508241
462 10.627285 10.592903  8.009031  8.035279 10.688028  7.689371  6.054439
463  8.715552  8.130942  9.637306  8.737773  8.307706  8.491055  9.456341
466 10.054834 10.093984 10.144589 10.070188 10.069637 10.068578 10.143646
468  9.924955  9.750511  9.629774  9.821844  9.815421  9.671366  9.697508
469 10.689988  6.978214 10.662610 10.688598  6.361302  7.372746  7.355641
475 10.118438 10.267714 10.215960 10.025263 10.109322 10.187350 10.024155
476  9.898877  9.820975  9.786954  9.717459  9.558106  9.869362  9.681656
477 10.284933 10.341226 10.352842 10.366057 10.276051 10.335465 10.327218
478  9.940061 10.248884  9.672942  9.597370 10.096790  9.736724  9.665611
479 10.111071 10.058524  9.966368 10.011624 10.131021 10.113303  9.979012
482  9.078864  9.277158  9.239414  9.291644  8.766394  9.134539  8.776784
484 10.606214 10.483102 10.647898 10.487740 10.462875 10.535105 10.505314
486 10.237421 10.533748 10.333710 10.517213 10.299811 10.399920 10.339385
489  9.622053  9.583145  8.981053  9.488199  9.562405  9.351666  9.307286
492  9.532641  8.992309  9.767324  9.811482  9.354960  9.405907  9.701861
499 10.324695 10.141441 10.149371 10.284728 10.297723 10.254532 10.127990
500  6.180017  4.859812  7.386471 10.679895  4.430817 10.680976  8.032685
      G1.T2.2   G1.T6.2   G1.T5.2   G1.T1.3   G1.T2.3   G1.T6.3   G1.T3.3
2   10.468801 10.436231 10.388380 10.426825 10.316722 10.377514 10.520698
4   10.443396 10.389979 10.289532 10.342484 10.391822 10.353607 10.331073
6   10.532176 10.554666 10.494464 10.510668 10.506683 10.508268 10.554171
7   10.295800 10.414093 10.333255 10.187576 10.386130 10.347243 10.141086
8    9.555560 10.018199  9.648402  9.829410  9.975994  9.479375  9.781885
12   9.051227  8.561975  9.026538  8.972083  8.241176  8.850374  8.583355
19   7.370231  8.304742  7.608871  7.491088  8.603371  7.917536  8.474912
21  10.518295 10.474213 10.424184 10.505396 10.420405 10.498333 10.410727
22  10.028798  9.920640  9.851457  9.875242  9.992597  9.921180  9.976692
26   9.793003  9.633514  9.712690  9.730681  9.587886  9.584108  9.697447
29  10.554744 10.494020 10.588300 10.501472 10.533588 10.636264 10.501555
30  10.534999 10.430226 10.634893 10.568852 10.402564 10.584132 10.591421
33  10.579768 10.613590 10.540488 10.518997 10.561551 10.632460 10.595334
36   9.248503  6.794587  8.755422  9.010913 10.663966  9.046880  9.093919
37   9.670357  9.524567  9.473089  9.384798  9.427466  9.409273  9.445808
39   9.236495  9.532859  9.405496  9.397401  9.283405  9.315061  9.279400
41   8.271548  8.910046  8.899185  8.981304  8.182559  8.463792  8.487764
44   9.833655  9.590966  9.686264  9.837615  9.614204  9.392745  9.764743
45  10.033770 10.035962  9.919115  9.881600  9.920640  9.904787  9.897872
51  10.400316 10.270939 10.421686 10.396658 10.359582 10.483998 10.214202
53  10.228827 10.269657 10.204333 10.290449 10.406654 10.136661 10.142819
56   9.253879  9.098179  9.404920  9.594718  8.908018  8.852093  9.332823
58  10.496372 10.176982 10.462389 10.414003 10.210016 10.180740 10.176183
59   9.780755  9.685456 10.065904  9.978456  9.699166  9.961521  9.796904
62   8.786457  8.942984  8.789203  8.861067  8.888067  9.094930  8.951051
63  10.154130 10.080168 10.141126 10.068748  9.942708  9.996887 10.103608
64  10.297858 10.141401 10.286809 10.172827 10.135155 10.309319  9.974784
68  10.311450 10.502379 10.203555 10.197835 10.461416 10.279249 10.444707
73   8.771835  7.573017  8.528133  8.674368  7.259116  8.351139  9.426580
74  10.418644 10.453890 10.526024 10.552030 10.492801 10.434557 10.511213
76   9.887511 10.237922  9.752258  9.771612 10.007893  9.890453  9.941602
80  10.582079 10.640723  3.713572 10.597035  6.282267  7.027315  4.912655
82  10.024687 10.116338 10.302129 10.121377 10.331268 10.289736  9.855767
84  10.670234 10.642373 10.646924 10.652046 10.673850 10.652093 10.619448
87   8.939450  9.331495  9.076123  9.214930  9.129239  9.055089  8.691315
91   9.709114  9.363662  9.651044  9.531771  9.576787  9.155779  9.113609
96  10.534866 10.239424 10.421597 10.459583 10.347757 10.437317  9.987691
97  10.403687 10.168387 10.398001 10.369420 10.268165 10.506218 10.032672
101  8.757469  9.025335  8.908830  8.962776  8.986822  8.424420  9.052750
103 10.274189 10.399007 10.340225 10.232288 10.341581 10.256185 10.218590
106 10.656789  7.532624 10.677477 10.685286  5.736572  7.717351  4.812184
107 10.173477 10.077525 10.026943 10.040725 10.143921 10.017753 10.071583
108  9.756321  9.909122 10.143881  9.979939 10.044249  9.598524  9.792779
109  8.939712  9.015663  9.009081  8.952088  8.965973  9.257892  9.185330
113 10.629513 10.510450 10.484138 10.545920 10.531056 10.574772 10.468034
114  8.615952  7.674617  8.772300  8.192294  7.564757  8.920790  9.003931
117  9.154405  9.073489  8.867287  8.920790  8.554104  9.101752  8.323608
119  9.218507 10.662048  9.189525  9.323401 10.592878  7.010312  9.074864
123  7.878534  8.000685  6.751101  7.679714  7.587311  7.600402  7.274480
125 10.223794 10.113870 10.180058 10.167351 10.060833 10.180778 10.172178
128 10.043249  9.621390  9.814547 10.086892  9.875757 10.228357  9.263881
130 10.569443 10.498057 10.460127 10.573724 10.532150 10.547313 10.628908
133  9.411647  9.172015  9.344871  9.328479  9.144521  9.589119  9.226312
138 10.343515 10.445521 10.229332 10.244627 10.397787 10.309353  9.935228
139 10.450105 10.403717 10.284079 10.330877 10.401775 10.434322 10.419211
141  9.875602  9.708992  9.961756  9.643161  9.717158  9.885324  9.976227
144  9.825526  9.896715 10.027429  9.906533 10.114032  9.826768  9.920148
153  6.769642  7.542744  7.621195  7.738488  7.933797  8.025843  7.634821
154  9.991361  9.969275 10.139350 10.072851  9.961615 10.094562 10.149879
157  9.722745  9.461177  9.716254  9.867549  9.608647  9.846706  9.578034
161 10.586256 10.531536 10.492329 10.557140 10.525031 10.561707 10.612090
165  9.663198  9.670925  9.465293  9.665674  9.703572  9.605216  9.406976
167  9.296426  5.459586  9.138415  9.262933 10.654455  9.468774  7.697575
168 10.360216 10.350127 10.379411 10.442434 10.293060 10.344095 10.329409
170 10.532976 10.626169 10.553153 10.590038 10.602269 10.468062 10.550800
174 10.453255 10.387394 10.276085 10.337929 10.341452 10.321639 10.319134
176 10.261057 10.027164 10.320519 10.237385 10.060491 10.283772 10.131937
178  8.518193  8.512583  8.647871  8.331345  8.379309  8.456594  8.401782
182  9.405249 10.173209  9.691593  9.568155 10.355295  9.256460  9.752607
183  9.776790  9.808957  9.813180  9.804551  9.852615  9.331495  9.711782
184 10.562794 10.623033 10.565995 10.552944 10.531323 10.601274 10.586786
185  9.455324  9.595807  9.652973  9.695233  9.630760  9.395907  9.387231
187  9.380336  9.589256  9.520982  9.626086  9.498522  9.621191  9.440102
188  9.221379  9.485849  9.044876  9.618469  9.325364  9.120525  9.594650
189  9.771612  9.771384  9.551658  9.401952  9.443197  9.481131  9.575331
190 10.006405  9.988472  9.995611  9.996021 10.016682  9.825580 10.014000
191  9.708081  9.718663  9.879400  8.993427  9.834137  9.823307  9.681344
192 10.486485  9.911158 10.638017 10.554327 10.022248 10.644472 10.604007
193  9.333619  9.381938  9.446282  9.546027  9.280519  9.534378  9.252537
196 10.283908 10.196008 10.376424 10.433498 10.174735 10.387240 10.257449
200  9.199381  9.546027  8.730044  9.095715  9.482122  8.842604  9.173780
204 10.289226 10.151714 10.526239 10.255446 10.297993 10.396689 10.356186
205 10.589862 10.582840 10.607921 10.552683 10.581597 10.588174 10.523768
207  9.613002  9.056256  9.238831  9.426097  9.269646  9.471242  9.190750
208  9.167955  9.266248  9.081711  8.988821  9.219895  9.085004  9.234350
211 10.541703 10.433645 10.370173 10.468261 10.475032 10.425757 10.568672
216 10.090714  9.978688 10.001929 10.037887  9.991544 10.039940 10.077861
222 10.590466 10.555995 10.545236 10.618103 10.448483 10.487099 10.579870
223 10.480747 10.493300 10.455532 10.467664 10.502956 10.448512 10.432674
224 10.024776 10.290789 10.290415 10.289906 10.219465 10.342323 10.269172
226 10.347885 10.616584 10.554379 10.558076 10.532203 10.390717 10.461874
229  9.379661  9.584315  9.315241  9.326433  9.571087  9.298076  9.324562
230  9.252346 10.012880  9.719565  9.694925  9.767439  9.495594  9.312446
233 10.316127 10.249486 10.066286 10.221978  9.965899 10.241922  9.912001
234  9.942420 10.041857 10.021271 10.010367 10.115732 10.009108  9.848715
236  9.383705  9.652202  9.091895  9.339964  9.564793  8.529517  9.308737
246 10.445143 10.383318 10.414123 10.417927 10.318837 10.451349 10.406231
248 10.126191  9.853194  9.977249 10.016682  9.728598 10.165352  9.932706
249 10.265976 10.294685 10.351565 10.346024 10.391208 10.400772 10.194850
250  9.441135  9.415971  9.445492  9.497097  9.506511  9.479986  9.448333
251  8.686598  8.271804  5.438079  8.471359  7.788626  8.318498  8.583730
253 10.412832 10.373272 10.344577 10.333710 10.366120 10.383101 10.397909
256  9.499871  9.567175  9.539572  9.346094  9.554285  9.381769  9.214233
257 10.308586 10.353894 10.347564 10.306717 10.329866 10.327709 10.434968
261 10.251182 10.441646 10.438694 10.440186 10.451985 10.478752 10.469398
262  9.008102  8.964568  9.147507  9.048997  8.836374  8.869258  8.896725
265 10.149019 10.264687 10.299306 10.254039 10.224774 10.100205 10.276739
269 10.569777 10.533535 10.510178 10.531162 10.487573 10.407289 10.516752
270 10.004915  9.620129 10.177210 10.026678  9.862874 10.077357  9.925787
272 10.109688 10.318672  9.990720 10.082303 10.277221 10.085851  9.712085
274  9.744433  9.358243  9.488956  9.667892  9.583971  9.576025  9.568784
277 10.599755 10.578293 10.682216 10.650010 10.601174 10.596260 10.589333
278 10.457832 10.304677 10.337443 10.355932 10.325154 10.434733 10.174659
280  9.765546  9.830809  9.717278  9.903137  9.795847  9.813946  9.800846
283 10.445812 10.526856 10.139310 10.093488 10.476978 10.349935  9.049115
285 10.268964 10.183805 10.289226 10.198207 10.212956 10.334880 10.280759
288 10.449873 10.477457 10.536433 10.518673 10.510069 10.465272 10.541782
295  9.205026  8.942722  8.806724  9.150378  8.686767  9.198673  8.784315
302  9.848820  9.647821  9.775711  9.924172  9.652459  9.673697  9.564372
306  9.968339  9.747418  9.937309  9.916552  9.495068  9.946547  9.793282
308  9.981420 10.166121 10.167120 10.121860 10.077399  9.990032 10.108426
310  9.322597  9.571714  9.482350  9.421492  9.459308  9.726273  9.362718
311  9.991773 10.126831 10.049059 10.018467 10.148784  9.953277 10.088971
312 10.633376  7.478735  8.413165  7.080868  8.360305 10.672924 10.674383
315 10.213946 10.228646 10.226187 10.181952 10.225172 10.243738 10.240138
317 10.273602 10.368510 10.385605 10.421239 10.470816 10.388226 10.378074
320 10.679297 10.395803  7.342779  7.707512 10.491413 10.571625 10.649630
325  9.449436  9.459931  8.869961  9.048527  9.251674  9.265018  9.129672
326 10.537601 10.419241 10.429310 10.422222 10.435292 10.475596 10.544157
329  9.588434  9.332912  9.948509  9.768584  9.400878  9.814820  9.531336
331 10.550800 10.448831 10.457373 10.472148 10.393508 10.496068 10.547103
332 10.109526 10.186333 10.030737 10.125911  9.978038 10.034472 10.064075
335 10.014000 10.144078 10.240103 10.274948 10.089303  9.948652 10.226295
337 10.316590 10.225825 10.415383 10.369515 10.361039 10.310052 10.346955
339 10.043423 10.286400 10.295732 10.364608 10.255868 10.011759 10.333613
343 10.034954 10.165813 10.014447 10.070569 10.105653  9.986633 10.169576
348  7.967973  7.754910  8.689969  8.807472  8.295798  8.922925  8.860783
353 10.013418  9.611664  9.984699  9.968807  9.678655  9.676336 10.010457
354  9.973899  9.887866  9.950753  9.983269  9.874213  9.852826  9.587612
355  9.275191 10.528061  8.789051  9.333619 10.465842  9.363748  8.765459
358 10.301088 10.373960 10.312779 10.287797 10.350702 10.386037 10.346281
363  9.817930  9.708324  9.717820  9.887815  9.812030  9.860528 10.266532
364  8.879612  9.300638  9.167746  8.892886  8.923458  8.761393  8.215547
365  8.787983  9.275472  9.369223  8.950014  8.952347  9.142597  9.008102
366  7.003065  7.303170  7.120444  7.602401 10.676231  8.584104  7.532624
372 10.221832 10.237600 10.333353 10.290653 10.202480 10.239067 10.209869
375  9.790543  9.688622  9.571993  9.755162  9.438989  9.748470  9.930714
376 10.674035  5.556828  7.828038  7.392648  7.985484  6.023448  7.934513
380 10.228249 10.303203 10.364419 10.328592 10.325252 10.305279 10.371771
381 10.453630 10.028445 10.241387 10.382048  9.976924 10.211671 10.167351
382 10.240495 10.247219 10.143213 10.161264 10.104467 10.248530 10.092578
384  8.756053  8.752898  8.833900  8.700681  8.860783  8.649974  8.859931
385  9.938034 10.026899 10.020025 10.094645 10.064458  9.981605  9.991178
387 10.526588 10.278803 10.434557 10.532496 10.352523 10.344642 10.423798
388  8.674539  8.445053  8.646993  8.821437  8.939581  8.778634  8.541105
391 10.046158  9.727168  9.731215  9.877708  9.757247 10.018868  9.801178
394  9.175956  9.166179  9.289244  9.195937  9.147507  9.022805  9.146548
399 10.085351  9.340930  9.854560 10.137690  9.060331  9.923486 10.077063
401 10.320057 10.060235 10.313376 10.310518 10.045942 10.212332 10.262525
413  8.183397  8.061487  8.022569  7.834392  7.717796  5.605802  6.295266
416 10.468915 10.660876 10.543919 10.471553 10.647756 10.599855 10.452302
420 10.230414 10.152611 10.312048 10.368604 10.205257 10.365805 10.112613
422  9.602855  9.573941  9.596079  9.719384  9.530320  9.200189  9.657459
426  8.764990  8.715388  8.576028  8.757312  8.211483  9.120197  8.860073
427  6.723832  8.010028  8.455743  7.804659  8.137980  8.110427  8.585412
430  9.483873  9.303284  9.298992  9.434204  9.037296  9.382191  9.374243
431 10.442901 10.357679 10.398854 10.391822 10.444241 10.438606 10.465272
437 10.552082 10.518295 10.564163 10.541994 10.445318 10.456654 10.468119
439 10.410516 10.451407 10.419748 10.386099 10.461101 10.352523 10.337054
441  9.976227 10.235737  9.988885 10.140061 10.124389  9.689242 10.200030
445 10.534360 10.270731 10.477795 10.467067 10.241173 10.521696 10.361672
446 10.441792 10.337086 10.410697 10.479511 10.380777 10.417777 10.441851
447  8.360539  6.597146  6.590301  8.226573 10.683477  8.111028  7.918265
450  9.600286  9.791214  9.508295  9.663198  9.761982  9.753536  9.783239
451 10.195709 10.078659 10.253405 10.197798 10.135749 10.334978 10.232971
454 10.463332 10.224048 10.240745 10.104835 10.139113 10.460930 10.373772
456  9.666118  9.740380  9.791158  9.702778  9.842729  9.730859  9.873389
457 10.479960 10.396017 10.330453 10.455992 10.435850 10.532203 10.518214
459 10.203888 10.218663 10.124629 10.145963 10.271977 10.195635 10.293501
460 10.485452 10.521372 10.602890 10.615677 10.515425 10.540488 10.571317
462 10.538529 10.601448  7.964503  6.913737 10.644353 10.683088  5.820083
463  9.655539  8.959055  9.197863  9.200593  8.944159  9.622913  9.180500
466 10.030032 10.028092 10.130782 10.106388 10.041378 10.099260 10.136977
468  9.623046  9.851773  9.840920  9.677528  9.840761  9.530828  9.976180
469  7.974533  7.567346 10.666301  6.579251 10.681711  7.232733 10.627818
475 10.218006 10.274672 10.300114 10.204481 10.370236 10.056809 10.101887
476  9.797182  9.571017  9.885782  9.785548  9.698245  9.859640  9.699166
477 10.348462 10.280313 10.324859 10.320354 10.331594 10.351022 10.269657
478  9.731453 10.121015  9.541441  9.527557 10.190732  9.740086  9.772695
479 10.015342 10.052037  9.978456  9.977249 10.130225 10.032057 10.057967
482  9.158099  9.000236  9.369393  9.335474  9.049467  8.834191  8.190354
484 10.568107 10.578318 10.470646 10.520401 10.560800 10.591170 10.494104
486 10.527820 10.299104 10.398489 10.545394 10.277668 10.357012 10.586130
489  9.421816  9.587475  9.381432  9.261033  9.545455  9.037771  9.564512
492  9.722146  9.194821  9.871119  9.888019  9.566195  9.948604  9.853457
499 10.024244 10.340451 10.176754 10.124308 10.467693  9.930957 10.248282
500  8.020599 10.658294  7.758333  8.429236  7.307202  7.171657  6.787845
      G1.T4.3   G1.T5.3   G1.T1.4   G1.T2.4   G1.T6.4   G1.T3.4   G1.T4.4
2   10.389826 10.331431 10.374772 10.443076 10.413493 10.242528 10.453572
4   10.437346 10.236776 10.227200 10.468659 10.249945 10.173324 10.231207
6   10.554849 10.547970 10.537389 10.506901 10.521399 10.492773 10.495377
7   10.355868 10.491885 10.324859 10.332409 10.389734 10.302499 10.290619
8   10.007532  9.942516  9.832475  9.769327 10.012252  9.879758  9.848345
12   8.173293  7.968666  9.089302  8.987322  8.377931  8.240121  8.891787
19   8.343792  8.315566  8.193953  7.646831  8.010360  8.115820  7.948738
21  10.457200 10.426202 10.397391 10.492357 10.444881 10.412081 10.451262
22   9.841506  9.823524  9.875397  9.913685  9.867238  9.837615  9.917045
26   9.692211  9.769499  9.671429  9.709539  9.591240  9.611463  9.576857
29  10.501555 10.542258 10.593856 10.588174 10.452129 10.557400 10.550015
30  10.435732 10.295192 10.544525 10.604256 10.473280 10.440858 10.533562
33  10.578547 10.494879 10.532683 10.545762 10.643685 10.555370 10.620424
36   6.946014  7.616776  8.793612  9.048527 10.645615  8.056427  9.168685
37   9.292842  9.296243  9.451638  9.480520  9.546455  9.399969  9.623641
39   9.342421  9.201300  9.392162  9.269175  9.392162  9.103423  9.490847
41   8.232440  8.424859  8.757312  8.711937  8.581857  8.808369  8.875287
44   9.627866  9.598998  9.822657  9.797349  9.562827  9.519441  9.674829
45  10.001113  9.956080 10.002428  9.860110 10.031793  9.844746  9.848873
51  10.360976 10.310452 10.520941 10.489690 10.247786 10.260112 10.419808
53  10.465643 10.297588 10.192531 10.268686 10.449815 10.349871 10.116985
56   8.965207  8.776784  9.368625  9.132163  9.229849  8.733111  9.353401
58  10.102379 10.119727 10.357616 10.417209  9.923878 10.194738 10.347596
59   9.545955  9.571226 10.098602  9.915268  9.471704  9.485697  9.918179
62   8.911125  8.959697  8.879751  8.788746  9.038721  8.849944  8.783703
63  10.030473 10.063350 10.033682 10.007127 10.078743 10.125751 10.069299
64  10.105775 10.283669 10.269276 10.339547 10.213799 10.209353 10.317846
68  10.523419 10.428246 10.312214 10.218116 10.294110 10.392466 10.382977
73   7.532088  7.624131  8.048149  8.645410  6.562444  7.972466  8.646641
74  10.495958 10.495598 10.504876 10.441996 10.507202 10.520914 10.459009
76   9.998980  9.981744  9.732936  9.717218 10.033682  9.858176 10.046852
80  10.626266 10.678883  6.419995 10.581445 10.539138 10.635423 10.528650
82  10.286877 10.152221 10.210457 10.207805 10.046852 10.016861 10.171298
84  10.642134 10.647969 10.644281 10.618641 10.650223 10.667093 10.625635
87   9.251770  9.174299  8.941284  8.994669  9.206031  9.147294  9.188504
91   9.661416  9.660396  9.749462  9.618203  9.329722  9.584040  9.473320
96  10.099712 10.245161 10.412982 10.463874 10.119405 10.174621 10.521723
97  10.295361 10.061986 10.501939 10.315564 10.038455  9.976738 10.400681
101  8.928243  9.128154  9.227689  8.437717  8.871646  8.868976  8.855378
103 10.383565 10.308219 10.293060 10.237636 10.351980 10.340677 10.330257
106  6.539586  6.761573 10.665274 10.681803  7.271704  7.152269  5.231109
107 10.171796 10.167466 10.141165 10.042684 10.115408 10.118075 10.081425
108  9.905186  9.780755  9.790487  9.849929  9.799903  9.740969  9.914576
109  8.868695  8.966484  8.845345  8.978787  8.979669  9.204222  9.074979
113 10.520347 10.582460 10.529854 10.558829 10.577783 10.515994 10.575641
114  8.029433  8.421123  9.036820  8.632484  6.727432  8.305731  8.965590
117  7.512071  8.764522  9.224736  8.968651  8.713746  7.357556  9.099632
119 10.610439 10.520051  8.586346  9.562545 10.575130 10.455849  8.570355
123  7.877018  7.962067  7.428333  7.491645  6.206576  8.155936  7.945555
125 10.055049 10.128429 10.073019 10.094273 10.176982  9.999570 10.284353
128  9.898525  9.886087 10.064883 10.190132  9.694925  9.703145  9.977945
130 10.524467 10.541016 10.387641 10.557946 10.594758 10.508541 10.401501
133  8.917713  9.053920  9.455245  9.430038  9.194719  9.216919  9.460243
138 10.293941 10.405141 10.326629 10.326072 10.165621 10.248920 10.178236
139 10.352395 10.436290 10.369671 10.358917 10.356695 10.262629 10.228899
141  9.828818  9.752316 10.075927  9.714866  9.304013  9.875345  9.900232
144  9.945972  9.922800  9.823470  9.857496  9.989161  9.946499  9.845011
153  7.550661 10.675307  6.679599  7.459339  6.740519  7.079184  8.217708
154 10.051002 10.062882 10.164890 10.105653  9.979430 10.159137 10.159331
157  9.619133  9.592742  9.787066  9.848345  9.422949  9.744492  9.834834
161 10.624031 10.556984 10.570188 10.513688 10.631423 10.573059 10.626412
165  9.488124  9.324472  9.199279  9.498297  9.886748  9.601504  9.636457
167 10.632436 10.673202  9.494466  9.244935 10.569931 10.513824  9.448648
168 10.382141 10.283396 10.348750 10.319992 10.386901 10.305714 10.389365
170 10.606338 10.598907 10.559841 10.536407 10.653157 10.664106 10.548337
174 10.391515 10.452938 10.306516 10.355391 10.237349 10.390963 10.291908
176 10.107734 10.189944 10.345413 10.286741 10.120291  9.959206 10.236669
178  8.449984  8.319961  8.502486  8.531096  8.365905  8.230311  8.450412
182 10.013104  9.420277  9.342333  9.671366  9.806756  9.725974  9.246962
183  9.778264  9.699411  9.484253  9.665928  9.852300  9.383537  9.814383
184 10.581343 10.610562 10.601622 10.597334 10.486122 10.586003 10.612065
185  9.380842  9.398644  9.696094  9.510889  9.416053  9.626152  9.451560
187  9.444859  9.156095  9.443751  9.661543  9.484405  9.526610  9.656563
188  9.311090  9.285262  8.922525  8.867991  9.945541  9.708263  9.299541
189  9.545526  9.399555  9.420034  9.514142  9.487745  9.564793  9.290445
190 10.130185 10.028798  9.954086  9.901285 10.012611 10.063180 10.029459
191  9.806481  9.630037  9.694062  9.467615  9.572968  9.351579  9.543306
192 10.061773 10.375552 10.682262 10.532576 10.001204 10.174011 10.677408
193  9.303375  9.737728  9.525808  9.616272  9.006141  9.375601  9.679781
196 10.189080 10.167735 10.332897 10.355486 10.348910 10.206698 10.404808
200  9.469546  9.086590  8.666992  8.878219  9.692520  9.484253  9.180087
204 10.347757 10.359012 10.421805 10.307151 10.202555 10.330584 10.335302
205 10.573699 10.463932 10.622546 10.554249 10.450857 10.367945 10.515696
207  9.084324  9.239705  9.446677  9.217614  8.960981  8.938663  9.287487
208  8.997395  9.556480  9.360913  8.839856  9.285355  9.265018  8.820699
211 10.478527 10.345863 10.371301 10.399433 10.331594 10.521507 10.419211
216  9.688622 10.024333 10.038499 10.012880 10.084266  9.992780  9.986219
222 10.516590 10.498470 10.505013 10.535025 10.406352 10.585776 10.609896
223 10.572470 10.656341 10.538105 10.487935 10.542126 10.581242 10.409883
224 10.266045 10.247219 10.281342 10.333970 10.283635 10.275189 10.415473
226 10.579565 10.553597 10.492634 10.493050 10.586938 10.626412 10.486066
229  9.343997  9.471088  9.369990  9.286097  9.323401  9.680406  9.396156
230  9.838149  9.668904  9.941843  9.439227  9.727406  9.561208  9.743025
233  9.908624 10.021448 10.277496 10.141204 10.002020  9.913636 10.170992
234 10.043988 10.232216  9.917686  9.981744 10.049836 10.269865 10.005186
236  9.450380  9.429155  8.552560  9.174091  9.368967  9.486683  8.777093
246 10.397696 10.396047 10.426706 10.454898 10.307618 10.327709 10.338155
248 10.000160  9.577827 10.212515 10.048799  9.631088  9.363233 10.171949
249 10.312878 10.318177 10.345606 10.286366 10.305982 10.272669 10.371552
250  9.529012  9.427144  9.395574  9.498747  9.611597  9.482198  9.450931
251  8.096513  8.040125  4.867534  7.870166  8.734077  8.406485  8.187299
253 10.384709 10.386685 10.335627 10.379939 10.380125 10.334880 10.373460
256  9.864435  9.264165  9.403025  9.340667  9.585346  9.167224  9.488729
257 10.331236 10.362841 10.063649 10.246971 10.322165 10.269033 10.388934
261 10.498360 10.431288 10.376300 10.471468 10.532496 10.405323 10.520509
262  8.793915  8.685247  8.972464  8.963032  8.454466  8.595820  8.746716
265 10.282061 10.289124 10.271701 10.268026 10.344802 10.250511 10.262420
269 10.543814 10.550722 10.481308 10.480185 10.536619 10.528142 10.502324
270  9.748353  9.764743 10.061218 10.068663  9.810934  9.613536  9.877503
272 10.272289 10.214495  9.985943  9.969228 10.272462 10.267853 10.169001
274  9.478610  9.407468  9.373734  9.743554  9.435881  9.284520  9.482807
277 10.560723 10.500812 10.652755 10.616756 10.516048 10.494630 10.580124
278 10.353575 10.517808 10.356536 10.444095 10.345092 10.354659 10.375052
280  9.972454  9.680719  9.821029  9.794175  9.887765  9.777924  9.846864
283 10.190207 10.119244 10.473139 10.234337  9.630037  9.749928 10.567180
285 10.194738 10.128390 10.236023 10.320486 10.121498 10.272150 10.221723
288 10.536540 10.454207 10.538582 10.501582 10.453428 10.488882 10.507421
295  9.013474  8.416267  8.790269  8.771370  8.843326  8.641002  9.209740
302  9.601571  9.679156  9.751443  9.730383  9.845329  9.654449  9.620594
306  9.797794  9.493336  9.849823  9.896765  9.536329  9.706377  9.904487
308 10.089178 10.092578 10.090714 10.140889  9.778604  9.984422 10.185277
310  9.418736  9.407304  9.549167  9.629906  9.428753  9.795680  9.549024
311 10.171375 10.208359 10.036838 10.002065 10.155840 10.090506  9.997160
312  7.544332  7.360740  8.339262  6.511745  8.618485  8.069968  7.292337
315 10.266776 10.229693 10.151870 10.292451 10.273187 10.321836 10.304911
317 10.393294 10.399037 10.383380 10.403505 10.309952 10.475540 10.394335
320 10.536327 10.391331 10.666650 10.661064 10.644758 10.453717 10.604330
325  9.187686  9.057189  9.066932  9.029298  9.245418  9.298351  9.118883
326 10.505643 10.513172 10.437815 10.500619 10.469313 10.397513 10.411148
329  8.946505  8.116716  9.861050  9.774972  8.551788  9.081256  9.636914
331 10.454005 10.430551 10.447584 10.475314 10.404384 10.374022 10.505807
332 10.101067 10.016906  9.898525 10.054748 10.124669  9.847393 10.022026
335 10.117065 10.164466 10.270281 10.189531 10.000705 10.102256 10.247290
337 10.303505 10.334978 10.363409 10.364608 10.316855 10.260252 10.270350
339 10.231279 10.137650 10.221396 10.215777 10.287559 10.284113 10.163079
343 10.115489 10.076137  9.953325 10.076894 10.086850 10.074832 10.034647
348  8.476163  8.471987  9.018090  8.767173  7.862882  8.484463  8.863899
353  9.771384  9.684523  9.932658  9.807582  9.601774  9.718362  9.726810
354  9.784873  9.754581  9.784422  9.954656  9.808627  9.696771  9.651173
355 10.538131 10.460213  8.886824  9.358588 10.625028 10.495626  9.481741
358 10.317846 10.364608 10.328690 10.286775 10.337184 10.284353 10.274154
363  9.769156  9.683090  9.630891  9.985897  9.869776  9.634038  9.567595
364  9.262268  8.891374  8.830543  8.916774  8.987822  8.996033  9.088850
365  9.295325  9.545598  9.599541  9.244742  8.542861  8.977146  9.367686
366  7.039660  7.171657  7.981050  7.732808  7.070724  7.248504  8.331827
372 10.230306 10.246935 10.305145 10.267505 10.184372 10.226295 10.249875
375  9.823741  9.762960  9.650529  9.611396  9.554781  9.807087  9.888120
376  8.137103  7.896181  8.235361  7.262629  7.446001  7.864036  6.553933
380 10.388657 10.328396 10.381707 10.330453 10.388534 10.338123 10.367945
381 10.029371 10.109648 10.309386 10.336179  9.947265 10.048929 10.384864
382 10.059508 10.199919 10.161110 10.173515 10.131380 10.111396 10.213359
384  9.028699  8.516993  8.026170  8.571113  8.489616  8.589514  8.338067
385  9.836707  9.970024  9.880014  9.807747  9.982576 10.283498 10.042162
387 10.325613 10.224846 10.351884 10.500922 10.214386 10.290178 10.453745
388  8.142063  8.512382  8.752107  8.353497  8.727292  8.700181  8.551788
391  9.801953  9.808077  9.759906  9.876733  9.800901  9.894295  9.974412
394  9.079890  9.140025  9.213735  9.253879  9.106978  9.279307  9.430840
399  9.485469  9.069468  9.886697  9.973200  9.210540  8.706987 10.196940
401 10.124990 10.082428 10.246864 10.230090 10.149410 10.074580 10.242742
413  7.143618 10.663008  6.042633  8.042378  8.236950 10.686475  6.369901
416 10.658318 10.661767 10.480017 10.473337 10.556073 10.635158 10.563802
420 10.209464 10.164274 10.296070 10.218554 10.254884 10.133289 10.321507
422  9.657715  9.660524  9.600489  9.555348  9.416785  9.638219  9.722146
426  7.313220  8.173575  8.778480  8.455956  8.626765  8.018625  8.852522
427  8.218248  7.960324  8.703507  8.051660  7.844633  8.251925  8.214736
430  9.239414  8.973351  9.335209  9.285448  9.172846  9.174402  9.459464
431 10.395803 10.439893 10.399524 10.412772 10.387425 10.370361 10.344642
437 10.497477 10.384524 10.505725 10.509196 10.358790 10.473337 10.487210
439 10.401198 10.400620 10.309319 10.383596 10.412532 10.401562 10.368636
441 10.227128 10.213872  9.839216  9.546384 10.352651 10.254250 10.008253
445 10.151051 10.232180 10.563905 10.517023 10.122904 10.204851 10.466441
446 10.404051 10.298667 10.394733 10.415053 10.315067 10.341710 10.405716
447  6.091310  6.459904  6.622736  8.066521  6.896694  6.269096  8.372861
450  9.791941  9.559588  9.661671  9.638610  9.835155  9.727228  9.586789
451 10.114073  9.964771 10.228249 10.095718 10.229549 10.105938 10.221796
454 10.127111 10.049620 10.304844 10.031485 10.485228 10.293162 10.382699
456  9.747827  9.847235  9.768527  9.684336  9.812742  9.868689  9.774517
457 10.343386 10.435115 10.345317 10.418196 10.470873 10.427654 10.488966
459 10.330355 10.325220 10.178274 10.239603 10.232036 10.234121 10.144196
460 10.515750 10.471157 10.549491 10.566124 10.549098 10.501582 10.551925
462 10.641871 10.657565  7.915713 10.680125 10.607525  5.736572  7.950150
463  8.562740  8.809266  9.272470  9.535390  8.480114  7.837554  9.321524
466 10.152377 10.081592 10.013328 10.011400 10.073821  9.995884  9.915268
468  9.821301  9.814383  9.896110  9.578450  9.631876  9.690109  9.603328
469  6.670766  7.210818 10.659469  6.946014  6.161207  6.302619  6.901737
475 10.091335  9.950562  9.787178 10.257484  9.787178 10.269206 10.147022
476  9.883132  9.891415  9.922358  9.804330  9.497397  9.698675  9.845700
477 10.304911 10.348494 10.378417 10.349935 10.313144 10.319563 10.332832
478 10.141756  9.938130  9.489108  9.596487  9.482426 10.038281  9.531046
479 10.074580 10.141559 10.051433  9.964912 10.116379 10.103362  9.999933
482  9.137555  9.308374  9.284613  8.887515  8.749732  8.780941  9.206031
484 10.579641 10.541281 10.540990 10.455302 10.564525 10.455733 10.561759
486 10.253827 10.473308 10.368636 10.494990 10.236561 10.477288 10.329768
489  9.421978  9.473089  9.475010  9.014569  9.399638  9.382948  9.210140
492  9.539500  9.542015  9.747652  9.685767  9.519368  9.160415  9.875294
499 10.412471 10.098725 10.127351 10.218298 10.127750 10.232647 10.228502
500  8.121480  6.030685  8.260234  8.290293 10.645949 10.687206  8.319474
      G1.T5.4   G2.T1.1   G2.T2.1   G2.T6.1   G2.T3.1   G2.T4.1   G2.T5.1
2   10.438108 10.453630 10.561966 10.461388 10.524897 10.540805 10.663101
4   10.319068 10.124108 10.221323 10.308086 10.175954 10.362430 10.250829
6   10.543946 10.524978 10.599979 10.625198 10.559037 10.551847 10.613271
7   10.235055 10.412051 10.414153 10.347725 10.277462 10.583043 10.526909
8    9.952325  9.640693  9.760887  9.778888  9.642967 10.107978  9.426661
12   8.510571  8.905580  8.506334  7.983440  7.445418  8.739536  8.534050
19   7.891331  8.050703  7.945910  8.482395  8.850947  9.047821  9.280985
21  10.449642 10.368259 10.371395 10.394427 10.347083  9.911555  9.955178
22   9.855242  9.663643  9.680594  9.863915  9.890706  9.841931  9.542805
26   9.614404  9.674577  9.789927  9.762212  9.728956  9.926374  9.756842
29  10.474580 10.465928 10.384802 10.555057 10.590566 10.637345  7.574558
30  10.440156 10.568955 10.512057 10.210457 10.399403 10.301458 10.232216
33  10.531376 10.615726 10.598109 10.619228 10.558362 10.439922 10.523015
36   8.786609  8.274357  7.526718 10.674753  7.062192 10.105162 10.542073
37   9.489335  9.601166  9.362375  9.284241  9.241354  9.011767  9.331938
39   9.179778  9.535535  9.108861  8.904359  9.396654  6.795706  8.377701
41   8.849944  8.891236  9.139381  8.613594  8.092239  7.707962  8.212297
44   9.814000  9.747068  9.554852  9.819780  9.613068  9.881600  9.699902
45   9.944582  9.875911  9.976738 10.108834 10.062071 10.036137 10.168349
51  10.378541 10.411960 10.418375 10.433204 10.465500 10.553518 10.521291
53  10.277806 10.195074 10.337151 10.325515 10.107122 10.468205 10.477147
56   9.314430  9.044640  9.026538  8.797095  9.202207  9.144735  8.812099
58  10.322264  9.955511  9.903788  9.922996  9.973387  9.986081  9.842729
59   9.872048  9.544667  9.378309  9.117348  9.239511  8.483016  8.237215
62   8.813587  8.956866  8.845921  9.090994  9.234643  8.868413  9.004914
63  10.048843 10.139508 10.020381  9.893134 10.024864  9.955748  9.858176
64  10.271701 10.235772 10.382234 10.249061 10.166006 10.466555 10.392926
68  10.193018 10.362588 10.226151 10.322329 10.054232 10.596360 10.592752
73   8.361241  8.596559  7.750184  6.828712  8.171599  7.403061 10.682216
74  10.504848 10.435732 10.503038 10.284899 10.387918  9.807802  9.700637
76   9.756089 10.070780 10.171031 10.123105 10.180475  9.879912 10.069891
80  10.552474 10.518511 10.504985  7.983781 10.636216  9.562616  9.884763
82  10.080797 10.073146 10.204740  9.911704  9.981235  9.698982 10.137334
84  10.618812 10.587115 10.646234  7.267525  6.440947  8.063063  6.990257
87   9.174920  9.517752 10.046158  9.294865  9.277719  9.648337  9.436280
91   9.285448  9.442404  9.293302  9.498372  9.436041 10.143724  9.598998
96  10.430757 10.042336 10.105244 10.314239 10.102666 10.190920  9.797794
97  10.346056 10.321145 10.483382 10.360184 10.287967  9.726094 10.465814
101  8.631593  8.641356  8.612503  8.909370  8.592672  9.068777  8.987072
103 10.251112 10.416341 10.498305 10.449207 10.458378 10.469596 10.285855
106 10.677800  7.616776  7.440734  7.335634  8.174703  7.585281 10.582485
107 10.114761 10.049318 10.170648 10.290178 10.270073 10.215631 10.151129
108  9.811811  9.890098  9.570459  9.388487  9.716194  8.866441  8.931684
109  9.174299  9.088512  9.163249  9.118225  9.280146  9.112507  8.915298
113 10.511676 10.588577 10.487852 10.534440 10.551925 10.625587 10.591195
114  8.714568  8.247744  7.635304  7.666222  6.945051  9.655283 10.076222
117  9.036701  9.114490  9.291183  9.676712  9.374158  9.528721  9.601977
119  9.370161  8.479284 10.671951  8.147578  8.196161  7.801391  6.326149
123  7.363280  7.967973  8.174985  7.479300 10.656883  7.913887 10.614720
125 10.183427 10.375770 10.346537 10.258571 10.297858 10.226187 10.162616
128  9.964583  9.822657  9.388152  9.538132  9.050993 10.391485  9.822928
130 10.551480 10.556099 10.517348 10.567566 10.588527 10.622010  8.522976
133  9.429396  9.315871  9.090768  8.587279  8.786457  9.044522  8.765302
138 10.131101 10.197611 10.040419 10.236955  9.979986 10.604801 10.375957
139 10.311815 10.417329 10.223613 10.375084 10.424363 10.607426 10.588174
141  9.416378  9.448097  9.169414  9.603665  9.504278 10.000977  9.083189
144  9.920738  9.830917  9.562545  9.883234  9.870034  9.658290  9.664088
153  7.723120  8.003363  8.032035  6.992096  5.459586 10.670628  7.795235
154 10.034516 10.052985 10.050786 10.092661 10.021759 10.028621 10.178084
157  9.908077  9.443355  9.323758  9.508962  9.488805  9.618136  9.491375
161 10.543366 10.637249 10.611917 10.565428 10.485172 10.679067  7.433667
165  9.702350  9.729015  9.589530  9.093807  9.687878  9.506586  9.338030
167  9.393079  7.102499  8.891236  8.325548  8.137396  9.620461  9.229260
168 10.388995 10.379069 10.564809 10.241352 10.333125  9.900182 10.188102
170 10.611129 10.496234 10.525622 10.569623 10.565686  9.731631 10.326367
174 10.362936 10.424095 10.333970 10.262141 10.312613 10.296543 10.120854
176 10.267749 10.107367 10.238172 10.371113 10.192868 10.373522 10.311017
178  8.368461  8.140024  8.723069  8.805525  8.549660  8.819813  8.552174
182  9.503681  9.575469  9.280892  9.553008  9.379239 10.533375 10.296475
183  9.857758  9.818692  9.845382  9.486304  9.540579  9.671051  9.608445
184 10.559971 10.593731 10.533801 10.516455 10.519700 10.512492 10.505916
185  9.347926  9.538132  9.211140  9.237566  9.265113  9.202913  9.166388
187  9.529012  9.730324  9.852720  9.814328  9.900533  9.976552  9.756842
188  9.729789  9.794454  9.868793  9.379239 10.093116  9.151333  9.248599
189  9.391244  9.404920  9.445571  9.406894  9.641603  9.361429  9.247829
190 10.012028 10.066201 10.198840 10.206255 10.131539 10.214202 10.171413
191  9.456028  9.791718  9.668967  9.795735  9.633580  9.616872  9.853930
192 10.490913 10.501939 10.359234 10.437610 10.435468  9.772638  9.308283
193  9.304195  9.569343  9.513773  9.253208  9.042868  9.955321 10.206625
196 10.392987 10.377732 10.390072 10.019447 10.167773 10.125150 10.222341
200  9.035749  9.716736  9.380927  8.948066  9.322061  6.769642  8.690138
204 10.218262 10.418465 10.488855 10.486680 10.444736 10.149292 10.264443
205 10.498746 10.493078 10.458234 10.653110 10.622838 10.495045 10.552944
207  9.107089  9.376363  9.746015  8.985946  8.638171  8.181720  9.079890
208  8.976894  9.213535  9.170039  9.380758  9.502935  9.397732  9.237080
211 10.321573 10.264164 10.488158 10.040245 10.249556  9.988564  9.514585
216 10.105653  9.966275  9.921769  9.925787 10.133607  9.761405  9.764685
222 10.562871 10.568390 10.561189 10.437170 10.604107  8.687779 10.010277
223 10.485340 10.489884 10.497339 10.452505 10.411539 10.551873 10.462589
224 10.320321 10.409100 10.473704 10.419331 10.474919 10.481224 10.469313
226 10.483130 10.558621 10.572880 10.164351 10.300517 10.075759  9.846653
229  9.503532  9.278373  9.158837  9.266532  9.371098  9.235911  9.087834
230  9.832099  9.660588  9.521861  9.772752  9.201703  9.818148  9.959821
233 10.191107 10.247006 10.374522 10.544894 10.484445 10.494159 10.406200
234  9.859483 10.184183 10.176792 10.104958 10.042293 10.175383 10.270697
236  9.120744  9.381769  8.822175  8.679482  9.253112  8.736811  8.369157
246 10.458234 10.329605 10.340645 10.403293 10.328232 10.607674 10.433998
248 10.032101  9.894245 10.177970 10.328625 10.078575 10.262664 10.329049
249 10.358536 10.233079 10.117792 10.228754 10.309419 10.519214 10.351533
250  9.518707  9.386308  9.462965  9.376871  9.476007  9.525078  9.417273
251  8.161375  8.683724  8.443331  6.913737  7.630947 10.459267 10.654644
253 10.322625 10.523257 10.452100 10.417239 10.453342 10.409642 10.474693
256  9.523544  9.469700  9.371013  9.480444  9.750802  9.229849  9.144628
257 10.334230 10.424541 10.465386 10.434557 10.430078 10.367913 10.535955
261 10.406019 10.585245 10.390287 10.577401 10.565712 10.508022 10.571778
262  8.329175  8.720297  8.645059  8.626586  7.928406  8.644883  8.549079
265 10.247609 10.262595 10.262001 10.016816 10.301492 10.361166 10.358695
269 10.523983 10.538661 10.574798 10.368855 10.470192 10.386068 10.302029
270 10.013238 10.198989 10.368730 10.301492 10.369703 10.382699 10.353384
272 10.072977 10.223467 10.214898  9.933386  9.881242  9.583695  9.832904
274  9.761751  9.587132  9.524932  8.320448  9.191973  8.818334  9.593083
277 10.526695 10.598583 10.517673 10.312314 10.349327 10.444939 10.560308
278 10.270939 10.329147 10.213176 10.249415 10.264164 10.510968 10.314769
280  9.846917  9.822820 10.084725  9.509556  9.584865  8.798304  9.665294
283 10.165736 10.644496 10.497201 10.069807 10.137175 10.592878  3.850148
285 10.245232 10.127231 10.098643 10.094315 10.146983 10.081466 10.227128
288 10.395222 10.597984 10.512138 10.461302 10.324564 10.400985 10.331594
295  9.054739  8.911395  9.354700  7.334982  7.741099 10.310585 10.282711
302  9.834352  9.730621  9.621456  9.661607  9.721426  9.688498  9.925249
306  9.953658  9.797738  9.777187  9.432523  9.575608  9.659312  9.586789
308  9.921622  9.923045  9.859692  9.943045  9.700453  8.293550  9.342771
310  9.448963  9.397898  9.303193  8.919453  9.224243  9.169831  9.143559
311  9.940350 10.122904 10.158207 10.170533 10.299845 10.123225 10.235055
312  8.210668  8.088255 10.686750  8.293800  7.951559  9.214631  7.840706
315 10.281307 10.080713 10.241637  9.864643 10.021182  9.743201  9.917637
317 10.427920 10.340613 10.285070 10.251112 10.228140 10.342291 10.300383
320  8.194229 10.532549 10.648230 10.631302 10.640867 10.665087 10.566382
325  9.117457  9.477692  9.741439  9.763823  9.763536  9.849031  9.737669
326 10.481645 10.473025 10.488938 10.556125 10.512927 10.635423 10.499187
329  9.453287  9.269835  9.298626  8.394121  8.502080 10.481532 10.527874
331 10.496621 10.542627 10.540620 10.538979 10.491913 10.505752 10.594357
332 10.016548 10.169767 10.218262  9.778831  9.865682  9.401126  9.220687
335 10.178008 10.202629 10.203148 10.310452 10.334685 10.368604 10.298801
337 10.255868 10.183503 10.364640 10.299542 10.364293 10.292959 10.145963
339 10.303069 10.349006 10.385111  9.881344  9.932172  9.497697  9.443513
343 10.096048 10.154130 10.216143 10.313343 10.236884 10.146434 10.073399
348  8.412943  8.956351  9.094817  9.261224  9.081029  9.560293  9.419547
353  9.886087  9.600963  9.535246  9.614538  9.718422  9.623377  9.644069
354  9.889642  9.626284  9.538996  9.663389  9.914378  9.709903  9.506214
355  9.299541  8.608130  8.815815  6.345636  8.294300 10.137096 10.514339
358 10.276292 10.367222 10.444095 10.384431 10.439747 10.361830 10.315266
363  9.716314  9.987921  9.786336  9.579625  9.919705 10.483578  9.980911
364  8.797246  8.984819  8.335192  9.200290  8.272826  9.248888  9.063116
365  8.759512  9.172223  8.094989  8.694837  8.779250  8.580919  8.822912
366  8.001690  8.211483  8.410943  8.187855  8.473450  8.695507  8.643121
372 10.229693 10.176259 10.189794  9.959679 10.046072  9.993054  9.925151
375  9.677026  9.725258  9.862092  9.053219  9.596011  7.543803  8.902456
376  7.676937  7.044033 10.681137 10.681206 10.684256  7.097549  6.963190
380 10.296644 10.376487 10.374147 10.295732 10.340225 10.225788 10.348590
381 10.408376  9.790991  9.858647 10.003650 10.142504 10.242457 10.183200
382 10.240745 10.275327 10.326170 10.329735 10.395008 10.281444 10.341710
384  8.573574  8.689633  8.800114  8.927977  9.253879  9.568854  8.911395
385 10.099054  9.969743  9.792724 10.152845 10.009198  8.884887  9.456653
387 10.443921  9.953039 10.150465 10.188666 10.283635 10.181687  9.839642
388  8.387768  8.433377  8.841304  9.206533  8.978030  8.956093  9.274066
391  9.892224  9.872048  9.880731  9.634169  9.658546  9.354268  9.405660
394  9.333354  9.111845  8.974618  9.150590  9.261889  9.409519  9.295049
399 10.086684 10.288240 10.538158  9.646011 10.512002 10.022203  8.698848
401 10.280004 10.185013 10.193916  9.934599 10.047415 10.026634  9.982391
413  7.749322  8.504918  7.418181 10.551559 10.603635 10.487963 10.327578
416 10.541545 10.613566 10.494547 10.670443 10.545394 10.234373 10.395467
420 10.274913 10.302264 10.303773 10.349198 10.286571 10.398336 10.317780
422  9.732165  9.477386  9.471550  9.557894  9.303740  9.515690  9.465912
426  8.398410  8.757626  9.073718  9.104535  9.127719  8.858653  8.617220
427  8.517593  7.809135  8.011023  8.445697  7.855545  8.925986  8.430763
430  9.481359  9.951849  9.206834  9.098626  8.893023  9.165343  9.094817
431 10.380467 10.449671 10.421239 10.396322 10.598333 10.525649 10.419241
437 10.390871 10.424452 10.365679  9.948748 10.142898  9.932464 10.104263
439 10.399524 10.392589 10.459698 10.251359 10.355136 10.386130 10.412021
441 10.156112 10.301794 10.347789 10.010906 10.357330  9.714443  9.853299
445 10.513661 10.119123 10.199621 10.107978 10.012342 10.174926 10.231315
446 10.422995 10.364734 10.450221 10.156927 10.202258  9.927985 10.043815
447  8.385945  8.075894  8.685754 10.625829  7.278629 10.569109  7.630461
450  9.655603 10.043858 10.102994  9.869776  9.904937  9.553433  9.881293
451 10.196791 10.197164 10.261372  9.741792  9.995428  9.513182  9.507180
454 10.264374 10.359170 10.338285 10.240674 10.260987 10.404869 10.224302
456  9.735069  9.881395  9.889135  9.934356 10.074200  9.781828  9.877092
457 10.487545 10.383627 10.284455 10.277462 10.407530  9.500245 10.341484
459 10.180740 10.267575 10.054361 10.115651 10.103240 10.399403 10.368541
460 10.495515 10.596760 10.567952 10.342258 10.462389 10.344834 10.305614
462  3.555348 10.677085 10.647494 10.582764 10.603461 10.603387 10.624955
463  9.157572  8.866017  8.117312  8.798153  9.179675  9.465835  8.485909
466 10.062370  9.981975  9.977574 10.017084 10.147022 10.462989 10.095718
468  9.503010  9.793840  9.573524  9.798960  9.720946 10.334035  9.782788
469  5.913503  6.396930 10.674429 10.661064 10.639982  5.424950  7.069023
475 10.018645  9.166597  9.515101  9.474856  9.777357 10.209095  8.925321
476  9.784873  9.650271  9.288227  9.676838  9.329633 10.485563  9.860110
477 10.262944 10.251535 10.180437 10.289260 10.071879 10.576228 10.361166
478  9.280892  9.446677  9.172742  9.676399  9.624963 10.682950  9.631416
479  9.975808 10.087142 10.058609 10.141323 10.133050 10.046808 10.075843
482  8.908695  9.064389  9.240967  8.944811  8.906664  9.621058  8.658519
484 10.515858 10.554405 10.585372 10.457804 10.448686  9.828063  9.708202
486 10.469738 10.391423 10.288852 10.390133 10.329180 10.030561 10.240103
489  9.289336  9.018211  9.559870  9.655795  9.544811  9.554143  9.728539
492  9.611797  9.971380  9.884101  9.957928  9.665230  9.947696  9.882723
499 10.155918  9.809342 10.086767 10.061346  9.973760  9.549951  9.763363
500  8.615046 10.662399  6.811244 10.669467 10.637273  8.644354  8.139732
      G2.T1.2   G2.T2.2   G2.T6.2   G2.T3.2   G2.T4.2   G2.T5.2   G2.T1.3
2   10.588628 10.576126 10.596085 10.426024 10.526802 10.525729 10.592501
4   10.305848 10.323513 10.642014 10.608341 10.549307 10.621620 10.587241
6   10.632894 10.590642 10.598807 10.538555 10.646282 10.608020 10.597409
7   10.405050 10.590742 10.460729 10.553675 10.409944 10.470646 10.405081
8    9.524494  9.607370  9.099185  9.236593  9.607034  9.493788  9.463276
12   8.042056  8.073403  8.512984  7.397562  8.337349  8.058327  8.274102
19   9.223454  9.422625  8.470730  9.009325  8.951829  9.174920  8.867850
21  10.176868  9.816349 10.370079 10.046375 10.401137 10.274672 10.340451
22   9.759444  9.951516  9.714021  9.700637  9.800125  9.867757  9.815858
26   9.706316  9.634889  9.957170  9.851036  9.773493  9.948509  9.882366
29   8.327484  8.711773 10.410004 10.602468 10.652542  6.311735 10.398031
30  10.209758 10.315034 10.047891 10.091501 10.039983 10.233403 10.131658
33  10.550669 10.459009 10.491663 10.472799 10.492190 10.417957 10.481476
36  10.495211 10.537044 10.327480 10.383813 10.345252 10.554849 10.246687
37   9.092007  9.353488  9.380421  9.344784  9.040145  9.343734  9.501815
39   8.128585  8.426612  7.581720  7.036148  7.545390  7.743703  8.003029
41   8.155649  7.040536  8.467793  8.170186  7.987185  8.420682  8.053569
44   9.766407  9.680031 10.111639  9.929155  9.933823  9.979893 10.229043
45  10.119606 10.175116 10.127990 10.094851 10.062668 10.102051 10.039983
51  10.483578 10.488465 10.305614 10.627915 10.530815 10.454322 10.470788
53  10.536141 10.497588 10.505561 10.500124 10.462332 10.415413 10.452938
56   8.135054  8.644178  8.630522  8.706325  6.952729  7.980366  8.387085
58   9.933677 10.013238  9.825256 10.044466  9.914131  9.981652  9.936148
59   5.613128  8.074960  5.407172 10.665181  8.232440  8.457655  8.958669
62   9.109193  9.056490  9.392412  8.966739  9.239608  9.211140  9.302920
63   9.907231 10.051606  9.960057  9.948604  9.772125  9.884967  9.895002
64  10.378323 10.389488 10.293602 10.340484 10.457660 10.245764 10.323579
68  10.558154 10.632822  8.833754  8.044305  9.319015  8.423102  9.087268
73  10.626703 10.649203 10.683844  5.170484 10.678376 10.678030 10.683729
74   9.448727  9.657843  9.468388 10.093116  9.945349  9.538924  9.614538
76   9.903987 10.074537 10.112086  9.967213 10.045204 10.046548 10.242065
80   9.166911  9.573385 10.499545 10.394488 10.603213 10.618054  7.131699
82   9.898123  9.989252  9.904687  9.841187 10.017396  9.902787 10.060790
84   7.195187  7.847372 10.666557 10.689465  7.234177  6.629363 10.649654
87   8.861634  9.183277  9.471473  9.252729  9.102644  9.016027  9.046173
91   9.608915  9.737315  9.598320  9.595943  9.769899  9.529085  9.494541
96  10.044813 10.277462  9.813727  9.874059 10.200959 10.202814  9.922211
97  10.303035 10.334458 10.015744 10.187726 10.130583 10.085767  9.838842
101  9.154405  9.003562  9.247443  9.052516  9.467305  9.323758  9.331407
103 10.357902 10.309985 10.320980 10.381490 10.358600 10.348718 10.380312
106  7.814400  8.068090  7.710653  6.813445  7.793174  6.406880 10.639718
107 10.187500 10.148236 10.272634 10.266532 10.248211 10.162770 10.175802
108  8.657651  8.843471  8.823353  7.654917  8.503905  8.743532  9.170560
109  8.979291  9.103868  9.076695  9.068546  8.921725  8.929965  9.286190
113 10.615236 10.636793 10.605223 10.652590 10.607550 10.626873 10.618714
114 10.165082 10.171566  9.847340  9.492432 10.033814 10.145885 10.033419
117  8.890824  8.832442  9.046644  9.901486  9.223257  9.317130  9.269552
119  8.386629  8.290544  3.332205  8.379309  8.037866  8.554104 10.668653
123 10.539244 10.615137 10.609502 10.601871 10.663873 10.600253 10.643280
125 10.180399 10.093198  9.976134 10.219247 10.208100 10.143960 10.029106
128  9.807692 10.109404  9.689861  9.909072  9.959868  9.968948  9.755220
130  9.626943  8.959055  9.224145  9.516795  9.531046  9.601707  8.304742
133  8.693832  8.982184  8.985320  8.969923  8.471987  8.697346  9.185535
138 10.344577 10.389457 10.256992 10.278665 10.339417 10.374647 10.243205
139 10.377577 10.547733 10.444124 10.580861 10.478977 10.615726 10.395344
141  9.646593  9.377210  9.317130  9.286931  9.593355  9.491602  9.281730
144  9.812085  9.858595  9.625888  9.642772  9.873853  9.746073  9.654385
153 10.681275 10.649773  7.355002 10.678238  6.455199 10.679849  6.129050
154 10.237421 10.190582 10.171222 10.078365 10.149527 10.156035 10.113465
157  9.279027  9.581352  9.366404  9.798294  9.307104  9.362804  9.462732
161  7.224025  7.928046  8.799360  7.782390  9.619133  8.876405  8.823206
165  9.195633  9.141847  9.362804  9.439943  9.162829  9.182969  9.231613
167  8.844336  8.429018  7.627544  9.234447  9.305832  8.961238  8.754319
168 10.026280 10.015342 10.207510 10.083682 10.243311  9.975483 10.032233
170 10.458550 10.359329 10.499793 10.514719 10.539853 10.491108 10.457488
174 10.039983 10.206366 10.214679 10.163426 10.144785 10.355900 10.019269
176 10.322264 10.267401 10.350414 10.327054 10.447380 10.385605 10.309119
178  8.727940  8.671458  8.422443  8.716863  9.082280  8.955319  8.487146
182 10.433822 10.232432 10.603114 10.408738 10.561992 10.617882 10.301727
183  9.357639  9.321076  9.466300  9.219895  8.774004  9.295233  9.559517
184 10.397147 10.500949 10.411750 10.382482 10.336600 10.410305 10.438284
185  9.176784  9.453600  8.458504  9.574983  8.618124  8.859079  8.512783
187  9.429556  9.697877  9.680531  9.900433  9.474703  9.728598  9.947457
188  8.898366  8.829080  9.352534  9.560222  8.651724  8.758884  9.397732
189  9.271341  9.384714  9.200795  9.052868  9.228279  9.433884  9.363834
190 10.248813 10.073399 10.113424 10.123867 10.225644 10.187237  9.970866
191  9.893589  9.904637 10.196530 10.075043 10.163464  9.919312  9.911753
192  9.887612  9.869310  9.966650  9.757594 10.240888 10.255165  9.869414
193  9.395242  9.617471  9.990674  9.740616  9.330166  9.376617  9.751152
196 10.031969 10.031045  9.924711 10.051261  9.977760 10.100451 10.019001
200  8.074026  8.526549  8.629986  8.390723  8.637107  8.296297  8.623174
204 10.296205 10.394549 10.373210 10.320123 10.444736 10.450539 10.306349
205 10.676785 10.657000 10.579514 10.546420 10.605198 10.620034 10.560774
207  8.259458  8.872908  8.715388  8.922658  8.664751  8.257645  8.470521
208  9.505470  9.474626  9.523325  9.422949  9.630234  9.610793  9.224440
211  9.519955  9.485013  9.655731  9.785042  9.692149  9.502935  9.512221
216  9.594241  9.845753  9.739084  9.822928  9.540004  9.907480  9.625096
222 10.252700 10.073737 10.162963  9.873544 10.355677 10.156073 10.115611
223 10.386870 10.448483 10.417179 10.526320 10.438020 10.446625 10.386006
224 10.353193 10.399220 10.345510 10.496455 10.312214 10.353320 10.407137
226  9.293118  9.637241  9.332823  9.449121  9.226607  9.382612  9.450066
229  9.220984  9.340667  9.089753  9.091106  9.494918  9.378817  9.318118
230 10.116136 10.063904  9.633514  9.760137 10.031001  9.955368  9.613135
233 10.159369 10.385142 10.286946 10.615775 10.263572 10.366057 10.302029
234 10.204592 10.117106 10.216362 10.246439 10.121458 10.053587 10.307151
236  8.314097  8.504716  8.868554  8.761080  8.466321  8.778172  8.619208
246 10.437698 10.484473 10.427002 10.409250 10.446655 10.461044 10.411449
248 10.237099 10.013821 10.157199 10.253264 10.420017 10.257940 10.004192
249 10.440156 10.322658 10.367222 10.498939 10.353288 10.360058 10.519295
250  9.341544  9.366917  9.153770  9.325810  9.121509  9.339701  9.277438
251 10.605248 10.625587 10.592074 10.625004 10.641560 10.614327 10.648563
253 10.491496 10.434968 10.527874 10.545894 10.375832 10.471100 10.472120
256  9.208739  9.193398  9.376533  8.865876  9.290260  9.164401  9.103868
257 10.499518 10.456597 10.462818 10.435673 10.453572 10.412081 10.455446
261 10.624906 10.531429 10.417029 10.544868 10.583929 10.517916 10.488855
262  8.623713  8.334231  8.597113  7.871311  8.358666  8.437717  8.371011
265 10.353512 10.407137 10.262874 10.221541 10.305714 10.394121 10.271389
269 10.300517 10.279798 10.383503 10.307285 10.128749 10.340710 10.367567
270 10.598009 10.456050 10.260112 10.062370 10.335335 10.331431 10.260112
272  9.541297  9.576857  9.772524  9.846388  9.570948  9.476084  9.820378
274  9.257224  9.146974  9.202611  9.420034  8.870242  9.145695  8.662505
277 10.313973 10.444357  9.672627  9.479298  9.776279  9.583420  9.983546
278 10.235306 10.337508 10.309552 10.505314 10.421626 10.470675 10.190057
280  9.404590  9.544095  9.587475  9.687320  9.657459  9.638023  9.701004
283  8.826735  7.160069  9.932804 10.466469 10.524467 10.262175 10.346248
285 10.094356 10.275224 10.106306 10.063137 10.097944 10.187500 10.185654
288 10.440712 10.283737 10.218955 10.116379 10.344352 10.315200 10.377078
295  9.958496 10.114437 10.192943 10.224375 10.342903 10.240888 10.236131
302  9.746132  9.654898  9.978966  9.817439  9.903438  9.674515  9.946595
306  9.360741  9.494090  9.705098  9.572759  9.481664  9.449357  9.657139
308  9.667195  9.395574  9.247925  9.061608  9.653487  9.512221  9.414179
310  8.963288  9.479986  8.727778  8.914492  8.772300  9.232982  9.275847
311 10.235737 10.284250 10.217787  9.942612 10.199101 10.241280 10.158556
312  8.805225  8.001355  9.452423  9.044286  7.271704  7.826842  8.774004
315  9.720466  9.899429  9.964018  9.756321  9.652909  9.761463 10.004057
317 10.304007 10.333385  9.991590 10.245658 10.204148 10.397116 10.248813
320 10.616560 10.581267 10.626242 10.644877 10.579158 10.613394 10.599655
325  9.670672  9.754233  9.779284  9.857025  9.591240  9.717278  9.702900
326 10.498139 10.606635 10.522073 10.514285 10.553597 10.477429 10.441529
329 10.527231 10.481701  8.642239  7.661056  9.499946  9.059169  9.308102
331 10.562406 10.498084 10.581521 10.499022 10.601199 10.512845 10.617540
332  9.257415  9.273221  9.424968  9.441611  9.434603  9.510223  9.523325
335 10.235772 10.407047 10.251571 10.319761 10.236525 10.332734 10.327349
337 10.327774 10.273118 10.000297  9.815858 10.179565 10.174430 10.144825
339  9.114820  9.135293  9.096500  9.100302  9.125109  9.118225  9.227984
343 10.285377 10.160569 10.160685 10.319068 10.140139 10.218408 10.082387
348  9.493864  9.285170  8.962648  9.006877  9.495895  9.333708  9.002701
353  9.499197  9.700269  9.613803  9.630037  9.538276  9.631219  9.720766
354  9.607975  9.721546  9.371438  9.768641  9.458606  9.485393  9.398561
355 10.458722 10.358663 10.241566 10.306015 10.368227 10.268721 10.257203
358 10.397665 10.357489 10.401653 10.377016 10.353544 10.397086 10.350127
363  9.934065  9.924809 10.112126 10.088514  9.951182 10.034954 10.026103
364  8.742734  8.140898  7.392032  8.292799  8.783856  7.679714  6.966024
365  8.899458  8.869258  9.151757  8.928508  9.182661  9.402695  8.483223
366  8.550821  8.558911  8.714239  7.954723  8.516793  8.418036  8.413165
372  9.945828  9.936003  9.872564  9.997934  9.984007 10.127511  9.955036
375  7.929126  8.728102  8.459352  8.669399  8.716208  8.766706  7.656810
376  6.900731  7.990915  6.028279  7.045777  6.981935  7.496097  6.006353
380 10.305413 10.362809 10.226947 10.219575 10.289566 10.274396 10.247999
381 10.059807  9.947983 10.399220 10.013776 10.182898 10.174240 10.238351
382 10.331953 10.266741 10.305145 10.326465 10.337411 10.237779 10.334913
384  9.029058  8.570544  9.538852  8.874728  9.362632  8.945984  9.433244
385 10.018556  9.454854  9.681344  9.703816  9.972687  9.872564  9.792612
387  9.976877 10.019447  9.739143  9.962181  9.897771  9.840814  9.922113
388  9.297160  9.121728  8.902456  9.035511  9.081370  8.921725  9.098179
391  9.214432  9.606832  9.206834  9.163773  9.372374  9.583558  9.058820
394  9.230437  9.317938  9.335386  9.365976  9.324205  9.361773  9.344696
399 10.648753  8.933928  8.577912  8.646290  8.304000  8.768574  8.476788
401  9.904986  9.972874  9.999843  9.722086  9.692087  9.939916  9.949034
413 10.295901 10.329833 10.551507 10.576585 10.475258 10.379722 10.588729
416  8.355615 10.517240  9.086024  7.780303  9.564723  7.551187  8.800415
420 10.273982 10.164582 10.344095 10.456424 10.374772 10.291467 10.447409
422  9.369734  9.485317  9.729372  9.575816  9.570041  9.447466  9.777017
426  9.125327  8.811950  8.697179  8.890824  9.049819  9.063347  8.960468
427  8.480944  8.263848  8.786304  8.775086  8.672315  8.911395  8.663542
430  8.851520  8.431853  9.058587  9.220192  8.539346  8.811652  9.052985
431 10.354340 10.489996 10.456970 10.504300 10.412652 10.468034 10.397665
437  9.929594  9.967870  9.699595  9.532206  9.859901  9.774233  9.857758
439 10.303639 10.349359 10.326858 10.257028 10.172178 10.252629 10.236884
441  9.645429  9.567525 10.101231  9.984007  9.772581  9.567945 10.187538
445 10.201293 10.208727 10.142386 10.138481 10.318738 10.116944 10.241673
446  9.816949  9.871636  9.748937  9.923584 10.040768  9.771726  9.948748
447 10.559763 10.663849 10.376424 10.504026 10.401805 10.535132 10.553466
450 10.004644  9.815858 10.059636  9.968010  9.731631  9.933095  9.844321
451  9.078864  9.283498  9.335739  9.619399  9.358588  9.200997  9.375855
454 10.185881 10.186710 10.317615 10.553858 10.290857 10.541518 10.440945
456  9.966744  9.830917  9.842463 10.188027  9.952373  9.829572  9.696894
457 10.338544 10.378417 10.239067 10.322954 10.223358 10.463960 10.084975
459 10.359963 10.375302 10.353320 10.384802 10.200179 10.303605 10.272980
460 10.207400 10.261442 10.202258 10.218043 10.504081 10.239317 10.319728
462 10.591949 10.642516 10.377265 10.612951 10.540884 10.592677 10.588199
463  8.120589  9.040975  7.620705  8.781862  7.860956  8.840870  6.234411
466 10.122663 10.286366 10.189193 10.177400 10.090423 10.299811 10.193841
468  9.892477  9.917045 10.055651  9.896463  9.920984  9.959206  9.944102
469 10.627043  5.852202  6.841615  7.334329 10.622302  5.855072  7.627057
475  9.478151  9.633907  8.163941  8.925188  9.320629  9.641408  9.327590
476  9.646787  9.994927  9.866875  9.894548  9.848662  9.770242  9.708020
477 10.306884 10.449149 10.366372 10.415323 10.371865 10.358251 10.266115
478  9.639001  9.567035  9.875345  9.963594 10.012790 10.170150  9.815912
479 10.172636 10.162809 10.149371 10.081759 10.227128 10.186371 10.153312
482  8.022897  8.820699  8.775240  8.745284  8.561593  9.095603  8.337588
484  9.493788  9.755683 10.068324  9.969369 10.083139 10.013283  9.749112
486 10.404536 10.089884 10.167197  9.948365 10.330388 10.183918 10.105407
489  9.856291  9.642772  9.546241  9.206533  9.881089  9.899228  9.702044
492  9.973433  9.893488  9.709903  9.865890  9.868068  9.900583  9.664278
499 10.145296  9.871429 10.080336 10.128988 10.269692 10.196269 10.306583
500  6.882437  7.387090  8.108623  7.754910 10.656412 10.674244  7.799753
      G2.T2.3   G2.T6.3   G2.T3.3   G2.T4.3   G2.T5.3   G2.T1.4   G2.T2.4
2   10.583271 10.514014 10.381738 10.571650 10.502159 10.524897 10.524360
4   10.650578 10.541148 10.647257 10.574133 10.561655 10.175954 10.503066
6   10.581927 10.623325 10.577121 10.652282 10.583043 10.559037 10.558102
7   10.491274 10.394090 10.387795 10.456827 10.445318 10.277462 10.486234
8    9.478228  9.639457  9.644652  9.618070  9.798738  9.642967  9.521055
12   8.220672  7.769801  6.318968  8.473659  7.483807  7.445418  6.722630
19   8.700348  8.777710  8.984568  9.024613  8.524963  8.850947  8.926650
21  10.295394 10.229188 10.253616 10.202925 10.201664 10.347083 10.050355
22   9.732343  9.722685  9.776620  9.667575  9.872048  9.890706  9.790991
26   9.806040  9.806205  9.806536  9.922898  9.857182  9.728956  9.911208
29  10.447932 10.542047 10.633762 10.561759 10.542363 10.590566 10.674151
30  10.388749 10.027518 10.058267 10.035042 10.243347 10.399403 10.192980
33  10.520347 10.504848 10.371427 10.506464 10.478836 10.558362 10.568055
36  10.334815 10.449410 10.538847 10.453428 10.449439  7.062192 10.607129
37   9.571157  9.290998  9.206634  9.412056  9.329101  9.241354  9.243582
39   8.510773  8.521982  8.282736  8.524566  8.885718  9.396654  8.565412
41   8.472614  8.231376  8.316300  8.004700  8.105308  8.092239  7.418781
44  10.110827  9.895052  9.768183 10.137096 10.218554  9.613068  9.874574
45  10.068451 10.059765  9.905486 10.141362 10.025749 10.062071 10.196679
51  10.459698 10.482822 10.577528 10.340484 10.598583 10.465500 10.544130
53  10.509960 10.466213 10.381676 10.393937 10.457085 10.107122 10.424333
56   8.282230  7.671827  7.687080  8.025516  8.108021  9.202207  8.343792
58   9.830164 10.144785  9.799459  9.908027  9.986587  9.973387 10.085392
59   8.972844  9.556197  9.189831  9.393079  9.151439  9.239511  9.457122
62   9.188095  9.153876  8.933532  9.186867  9.185228  9.234643  9.202510
63   9.988839  9.958638  9.815639  9.893892  9.808737 10.024864  9.949416
64  10.409672 10.410034 10.323611 10.206107 10.300181 10.166006 10.223939
68   9.213635  9.490771  9.320718  9.905236  9.812523 10.054232  9.967495
73  10.678606 10.678123 10.655587 10.634797 10.678030  8.171599 10.675792
74   9.765317  9.885273  9.987921  9.878067  9.780642 10.387918  9.972407
76  10.078449 10.242813 10.005096 10.149449 10.147688 10.180475 10.212699
80  10.641943  9.726034  7.220374  8.827761  7.039660 10.636216  8.975883
82  10.186860  9.904637 10.096873 10.159331 10.121377  9.981235 10.075085
84  10.678652 10.673411  7.772753 10.682583  6.949856  6.440947  6.762730
87   9.037652  9.124238  8.946896  9.116908  9.298443  9.277719  9.037177
91   9.296151  9.670925  9.624170  9.363147  9.616205  9.436041  9.532714
96   9.906732 10.217714  9.951039  9.952421 10.244699 10.102666 10.226078
97   9.804109 10.047848  9.882570 10.325384 10.200662 10.287967 10.178426
101  9.037177  9.276503  9.228966  9.111514  9.133567  8.592672  8.996280
103 10.408707 10.353257 10.198580 10.396994 10.380529 10.458378 10.443250
106  7.286876  7.167038  7.781973  6.925595  7.929487  8.174703  7.487734
107 10.126951 10.301995 10.246935 10.257028 10.218882 10.270073 10.091004
108  8.851520  9.609049  8.539150  9.493035  9.043223  9.716194  9.590351
109  8.950662  8.888067  8.776630  9.137017  9.148359  9.280146  8.996652
113 10.616756 10.605421 10.603263 10.578954 10.565118 10.551925 10.586332
114  9.858229 10.389672 10.122382 10.459583 10.234265  6.945051 10.565789
117  9.216024  9.464517  9.236788  9.596487  9.431883  9.374158  9.776165
119  7.404279  8.411833 10.665928  7.848543  6.992096  8.196161  8.838697
123 10.681619 10.664597 10.587922 10.646305 10.637225 10.656883 10.676093
125 10.014984 10.195784  9.899429 10.140139 10.272807 10.297858 10.159408
128  9.872874 10.098643  9.793673  9.355911  9.640433  9.050993  9.896564
130  8.092851 10.564266  8.382061  7.157735 10.637561 10.588527 10.537787
133  9.043577  8.603004  8.751316  8.785845  8.923191  8.786457  8.933532
138 10.278287 10.370769 10.218627 10.163040 10.144550  9.979986 10.345220
139 10.396383 10.420822 10.427476 10.412682 10.503395 10.424363 10.463160
141  9.088850  9.772410  9.641278  9.030496  9.410747  9.504278  9.930129
144  9.612333  9.932755  9.625492  9.696586  9.600963  9.870034  9.666055
153  6.634633  7.587817  6.860664  7.751475  7.848934  5.459586 10.636576
154 10.230883 10.239102 10.250935 10.174697 10.213249 10.021759  9.997979
157  9.367173  9.282289  9.604677  9.397815  9.495219  9.488805  9.487593
161  8.913147  9.581559  9.347752  9.595875  9.658737 10.485172  9.852247
165  9.374328  9.116469  8.799511  9.067855  9.318387  9.687878  8.785845
167  9.087042  9.395657  9.170455  9.178127  8.944028  8.137396  8.562358
168  9.997114 10.176145 10.070018 10.079078 10.090962 10.333125 10.266254
170 10.475427 10.410907 10.516509 10.381583 10.470448 10.565686 10.500537
174 10.027959 10.064500 10.331268  9.987645 10.089677 10.312613 10.229513
176 10.278184 10.349743 10.380187 10.376985 10.337767 10.192868 10.406473
178  8.720950  8.710455  8.968906  8.458716  8.669743  8.549660  8.411610
182  8.028455 10.517592 10.409160 10.088431 10.604479  9.379239 10.020915
183  9.548668  9.447387  9.018574  9.555135  9.550164  9.540579  9.636914
184 10.431937 10.398550 10.495073 10.486569 10.451464 10.519700 10.454639
185  9.077494  8.919854  8.912743  8.571871  8.805975  9.265113  9.107643
187  9.694740  9.450538  9.850614  9.670231  9.908326  9.900533  9.592332
188  9.391328  9.094256  8.811801  8.905716  9.359794 10.093116  8.964056
189  9.261129  9.432043  9.391995  9.344434  9.271530  9.641603  9.308646
190 10.103526 10.133885 10.289838 10.207547 10.115530 10.131539 10.116783
191  9.998025  9.941939 10.020426 10.164389 10.120653  9.633580 10.033199
192 10.149644 10.302566 10.541756  9.934211 10.328788 10.435468 10.594081
193  9.555843  9.142704  9.673949  9.384294  9.286468  9.042868  9.221181
196 10.180892  9.947552 10.016236 10.041204 10.099712 10.167773  9.781998
200  8.697179  7.873598  8.251403  8.616314  8.246696  9.322061  7.658228
204 10.270489 10.387394 10.400164 10.383194 10.277600 10.444736 10.539826
205 10.518187 10.678007 10.633232 10.641656 10.607129 10.622838 10.648990
207  8.484877  8.181441  8.516593  8.966994  8.997023  8.638171  9.107421
208  9.436838  9.499272  9.336532  9.488805  9.303557  9.502935  9.510445
211  9.620262  9.691655  9.535752  9.697877  9.630431 10.249556  9.706864
216  9.726750  9.754175  9.836011  9.692705  9.754465 10.133607  9.826336
222  9.979708 10.216289 10.221759 10.197164 10.313111 10.604107 10.332311
223 10.419599 10.443979 10.403899 10.405353 10.469227 10.411539 10.412081
224 10.344062 10.324564 10.428630 10.338285 10.366435 10.474919 10.495405
226  9.787066  9.434923  9.490696  9.445175  9.655859 10.300517  9.894043
229  9.250714  9.318477  9.179159  9.199381  8.959954  9.371098  8.988571
230  9.648208  9.899279  9.731394  9.519735  9.993328  9.201703  9.990170
233 10.373554 10.444153 10.271943 10.428482 10.467636 10.484445 10.598059
234 10.295766 10.202962 10.198915 10.059807 10.179413 10.042293 10.117590
236  8.625330  8.636042  7.225481  9.139167  8.472614  9.253112  8.818778
246 10.391638 10.435996 10.447119 10.344963 10.418315 10.328232 10.450365
248  9.981467 10.383936 10.409492 10.149175 10.290042 10.078575 10.273084
249 10.505451 10.410456 10.355645 10.432320 10.390656 10.309419 10.278115
250  9.274160  9.295325  9.052633  9.176163  9.432764  9.476007  9.364434
251 10.676393 10.649180 10.611523 10.660970 10.669211  7.630947 10.644734
253 10.461588 10.464588 10.435350 10.477654 10.424363 10.453342 10.451233
256  8.733111  9.366147  8.921458  9.083983  9.277064  9.750802  9.180190
257 10.345574 10.389149 10.373522 10.431672 10.426854 10.430078 10.445666
261 10.433910 10.549596 10.640843 10.509278 10.667023 10.565712 10.452302
262  8.729397  8.852236  7.324490  8.279190  8.519790  7.928406  8.585039
265 10.330616 10.327153 10.337508 10.340581 10.284353 10.301492 10.207031
269 10.362715 10.293568 10.077105 10.415982 10.262315 10.470192 10.264443
270 10.407319 10.496925 10.379318 10.537972 10.169691 10.369703 10.413523
272  9.898425  9.657971  9.821301  9.891617  9.607101  9.881242  9.608244
274  9.090881  7.878155  8.598404  8.876126  8.789508  9.191973  8.870944
277  9.955368 10.421954 10.193579 10.247893 10.257519 10.349327 10.461845
278 10.338997 10.296576 10.414903 10.254320 10.231712 10.264164 10.365144
280  9.854035  9.435083  9.528794  9.646658  9.714021  9.584865  9.527557
283 10.189305  9.840122 10.313907 10.214056 10.054662 10.137175 10.019625
285 10.205257 10.090921 10.078910 10.074242 10.070738 10.146983 10.140928
288 10.348910 10.475314 10.320123 10.463389 10.399737 10.324564 10.383070
295 10.347628 10.301492 10.373210 10.374022 10.392098  7.741099 10.528008
302  9.893892  9.852142  9.765891  9.877041  9.877400  9.721426  9.654449
306  9.567035  9.570320  9.321345  9.604475  9.410256  9.575608  9.452109
308  9.478381  9.708749  9.776903  9.455011  9.535318  9.700453  9.649820
310  9.258082  8.916774  9.142062  8.885303  9.222170  9.224243  9.187072
311 10.136185 10.179527 10.198170 10.043901 10.172751 10.299845 10.101190
312  8.417815  7.989560  7.792349  8.165932  7.292337  7.951559  7.896553
315  9.777811  9.780189  9.731097  9.951134  9.815093 10.021182  9.807307
317 10.370205 10.178806 10.339061 10.214862 10.328003 10.228140 10.243098
320 10.596410 10.635783 10.543287 10.600278 10.561033 10.640867 10.589384
325  9.593014  9.724480  9.598456  9.840335  9.607841  9.763536  9.849295
326 10.457603 10.544762 10.523715 10.563207 10.523741 10.512927 10.560697
329  9.278933  9.384126  9.081256  9.260843  9.422706  8.502080  8.931023
331 10.567000 10.531536 10.468517 10.568338 10.617589 10.491913 10.542812
332  9.493638  9.453287  9.152181  9.416460  9.511555  9.865682  9.569831
335 10.307852 10.228068 10.084308 10.304911 10.245658 10.334685 10.416161
337 10.322066 10.406352 10.008478 10.271424 10.246190 10.364293 10.252841
339  9.375855  9.215726  8.998137  9.594309  9.324294  9.932172  9.274441
343 10.243560 10.173477 10.091335 10.168157 10.240353 10.236884 10.231676
348  9.492130  9.248021  9.657587  9.091219  9.438432  9.081029  9.255218
353  9.678405  9.832689  9.588571  9.720586  9.686761  9.718422  9.855085
354  9.707777  9.771270  9.394161  9.660651  9.618402  9.914378  9.834834
355 10.380281 10.239603 10.320552 10.179565 10.323808  8.294300 10.404899
358 10.361419 10.369012 10.328951 10.380715 10.380343 10.439747 10.403808
363 10.139389  9.909122 10.116581 10.174278 10.107040  9.919705  9.882366
364  8.595820  8.716863  8.255569  6.403574  8.098035  8.272826  8.651199
365  8.659907  9.197458  8.854379  8.984443  9.394244  8.779250  9.262838
366  8.764522  8.308692  7.824046  8.309677  8.319230  8.473450  7.795235
372 10.015655  9.945637 10.011445  9.890807  9.956744 10.046072  9.980587
375  8.155936  7.925880  8.398635  8.489205  8.325791  9.596011  8.870803
376  7.494430  6.345636 10.686384  6.898715  7.265430 10.684256 10.679136
380 10.244592 10.241673 10.301391 10.241851 10.258641 10.340225 10.167120
381 10.206292 10.127231  9.975296 10.322823 10.299912 10.142504 10.007532
382 10.234229 10.258676 10.239388 10.311117 10.347340 10.395008 10.339029
384  9.134107  9.011402  9.177611  9.130864  9.108197  9.253879  8.830543
385  9.854350 10.086809  9.935471 10.094645  9.922015 10.009198 10.081383
387  9.849665  9.983592  9.978781  9.908923 10.099383 10.283635  9.936148
388  8.655040  9.141097  9.222170  8.970813  9.275379  8.978030  9.279773
391  9.235131  9.258654  9.411974  9.279120  9.401704  9.658546  9.551231
394  9.264734  9.279960  9.117018  9.245611  9.262933  9.261889  9.270588
399  9.259321  7.720905  8.596928  9.358415  9.481893 10.512002  9.645817
401  9.990445  9.984099  9.738495 10.051606  9.907380 10.047415  9.959632
413 10.585220 10.679596 10.417239 10.601672 10.588300 10.603635 10.485228
416  8.562167  8.466531  8.037543  7.799343  8.882669 10.545394  5.789960
420 10.418733 10.485368 10.360121 10.458234 10.331855 10.286571 10.338123
422  9.500544  9.549096  9.158310  9.788133  9.476314  9.303740  9.307830
426  8.735364  8.813141  8.893573  8.718009  9.131946  9.127719  9.153029
427  8.781709  8.688285  8.685078  8.351375  8.472405  7.855545  8.377701
430  9.091895  8.870523  8.894944  9.283498  8.979920  8.893023  9.078522
431 10.383534 10.385049 10.440595 10.446219 10.412411 10.598333 10.464845
437 10.013283  9.778094  9.776960  9.893942 10.108223 10.142898  9.800236
439 10.335952 10.262455 10.228791 10.302129 10.312646 10.355136 10.268339
441 10.034691  9.792053  9.822169 10.322132 10.118478 10.357330  9.847393
445 10.300315 10.319497 10.157509 10.251924 10.103649 10.012342  9.962228
446 10.027385 10.025263 10.020915  9.999797  9.917095 10.202258  9.971053
447 10.608168 10.573443 10.603859 10.631761 10.681688  7.278629 10.676347
450  9.849137  9.868534  9.647950  9.968104  9.881344  9.904937  9.900533
451  9.623112  9.488048  9.227886  9.582662  9.455871  9.995428  9.556621
454 10.263083 10.279284 10.377078 10.185843 10.324728 10.260987 10.326137
456  9.791102  9.959821  9.894245  9.733055  9.914576 10.074200  9.819508
457 10.145296 10.054576 10.381707 10.189080 10.210310 10.407530 10.196269
459 10.245125 10.122623 10.184749 10.297487 10.270939 10.103240 10.206662
460 10.407258 10.250900 10.311682 10.172522 10.450973 10.462389 10.157277
462 10.572265 10.508295 10.583296 10.562095 10.565428 10.603461 10.527499
463  7.462215  7.647309  8.437284  7.934872  7.835975  9.179675  9.137555
466 10.237349 10.087849 10.232252 10.313376 10.312646 10.147022 10.148119
468  9.781037  9.671555 10.094728  9.844693  9.785942  9.720946  9.976087
469  7.694393 10.595184 10.614082  7.348588  7.400010 10.639982 10.683729
475  8.892199  9.533221  8.858226  7.654443  9.633383  9.777357  9.531191
476  9.853194  9.727526  9.754988  9.671492  9.699718  9.329633 10.008793
477 10.342613 10.405656 10.321375 10.348077 10.357171 10.071879 10.331822
478 10.138836 10.099137 10.279661 10.106959 10.235342  9.624963 10.150426
479 10.122101 10.146943 10.145335 10.142426 10.150348 10.133050 10.146395
482  8.633375  8.882669  8.405815  8.106515  8.871926  8.906664  8.962648
484 10.015878 10.089801 10.064330  9.953087 10.137254 10.448686 10.281067
486 10.159950 10.453399 10.089469 10.242777 10.192157 10.329180 10.295394
489  9.437635  9.743964  9.559306  9.752374  9.616139  9.544811  9.792333
492  9.908724  9.949416 10.080755  9.775938  9.994379  9.665230  9.702839
499 10.100369 10.247822 10.388103 10.055178 10.119929  9.973760 10.317351
500  7.998671  7.603898  6.507278  8.547334  8.333511 10.637273 10.673341
      G2.T6.4   G2.T3.4   G2.T4.4   G2.T5.4
2   10.494131 10.470391 10.492079 10.451725
4   10.291162 10.323743 10.322560 10.274327
6   10.590893 10.595234 10.582967 10.590793
7   10.422847 10.480775 10.444328 10.334425
8    9.849137  9.944965  9.790935  9.924662
12   8.607582  8.875287  8.495970  8.160232
19   7.234898  8.668540  8.929303  8.806873
21  10.113627 10.246510 10.384369 10.324564
22   9.673886  9.745546  9.833441  9.804275
26   9.817276  9.676148  9.739438  9.760079
29  10.492135 10.474608 10.589660 10.556958
30  10.381831 10.569186 10.302062 10.384586
33  10.523203 10.589560 10.582663 10.493439
36  10.412081 10.657236 10.675862 10.684554
37   9.221379  9.018211  9.241548  9.179572
39   8.545975  9.067624  8.974618  9.022805
41   8.938138  8.651374  8.605753  8.935772
44   9.604879  9.639392  9.862405  9.665801
45   9.923486  9.945685 10.056595 10.017798
51  10.152455 10.480129 10.437991 10.500564
53  10.357171 10.316359 10.313077 10.415413
56   8.737292  9.149847  8.619750  8.959440
58  10.139863 10.248813  9.916601 10.020070
59   9.668904 10.179262  9.595399  9.477386
62   9.163982  9.257415  8.833900  8.715388
63  10.058952 10.085267  9.850298  9.961096
64  10.425639 10.212992 10.272980 10.358378
68  10.031661 10.381490 10.392650 10.217020
73   6.505784  7.638198  6.386879  7.661998
74  10.523096 10.554875 10.371270 10.379691
76   9.793338 10.107937 10.064883 10.058652
80  10.565196 10.456510  7.226209 10.670071
82   9.553504 10.082428  9.878272 10.096172
84   6.834109  7.130099  6.198479  7.734121
87   9.307921  9.757247  9.578934  9.494617
91   9.676148  9.553788  9.637763  9.603530
96  10.112776 10.024022 10.045031 10.221832
97  10.032320 10.333645 10.422728 10.339676
101  9.098515  8.893435  8.861067  9.049702
103 10.418315 10.480073 10.401501 10.405686
106  6.413459  6.844815  7.290293  7.203406
107 10.254813 10.162423 10.262699 10.117671
108  9.682404  9.824444  9.479527  9.543880
109  8.715552  8.966484  8.880725  8.949105
113 10.590365 10.577146 10.561629 10.449120
114 10.556880  4.941642  7.991592 10.664690
117  8.720134  9.462732  9.099297  9.599676
119  8.394800  8.649974  7.807510  8.495765
123  8.251664  6.712956 10.686635  6.955593
125 10.167120 10.287763 10.208359 10.297689
128 10.121257  9.699043  9.603598  9.849559
130 10.474834 10.548626 10.495626 10.433645
133  8.709630  8.950273  8.596928  8.750366
138 10.312978 10.310884 10.423085 10.242314
139 10.465899 10.427802 10.363125 10.367442
141  9.589462  9.320897  9.518266  9.928473
144  9.875859  9.617803  9.924564  9.729729
153 10.675099  8.098339 10.683179 10.670698
154  9.901586  9.962935 10.135512  9.915317
157  9.044522  9.344784  9.291367  9.608982
161 10.066626 10.586534 10.572188 10.408858
165  9.628327  9.548882  9.273033  9.384966
167  8.810609  9.373904  8.094684  8.911665
168 10.059465 10.310452 10.352587 10.295834
170 10.342420 10.526320 10.579209 10.577121
174 10.112532 10.188140 10.200179 10.315299
176 10.251782 10.342033 10.289124 10.301122
178  8.622094  8.556029  8.727130  8.933137
182  9.254262  9.306559  9.439307  9.378648
183  9.594582  9.675583  9.713477  9.562897
184 10.471808 10.489940 10.534254 10.506382
185  8.986572  9.768069  9.092907  9.319553
187  9.229849  9.809122  9.619333  9.861571
188  9.659631  9.608109  9.512295  9.661798
189  9.810604  9.699166  9.371864  9.574914
190 10.167005 10.223576 10.224665 10.262350
191  9.881191 10.001159  9.836493  9.792612
192 10.052855 10.369734 10.359709 10.423887
193  9.576857  9.550378  9.365548  9.246576
196 10.179793 10.337961 10.178882 10.255024
200  8.148156  8.879612  9.132163  9.027379
204 10.422192 10.350574 10.536460 10.503011
205 10.439659 10.537124 10.578980 10.518538
207  8.674710  9.537411  9.377464  9.236982
208  9.597438  9.292565  9.454541  9.420196
211 10.155219 10.347243 10.219684 10.184334
216  9.982437  9.838095  9.880526  9.987415
222 10.230342 10.495875 10.471723 10.546604
223 10.401046 10.512030 10.451580 10.469341
224 10.188290 10.454409 10.368981 10.405020
226 10.444707 10.649085 10.322658 10.466640
229  9.376617  9.068085  9.222170  9.364605
230  9.998661  9.869310  9.668651  9.687506
233  9.941169 10.418883 10.337994 10.519106
234 10.151285 10.006586 10.006766 10.065394
236  9.224440  9.310909  8.648748  9.093357
246 10.420226 10.361861 10.403687 10.392926
248  9.984145 10.410305 10.289974 10.163888
249 10.545105 10.359487 10.168003 10.354277
250  9.292473  9.406483  9.399389  9.467460
251 10.610661  8.056744  7.240650  8.057377
253 10.293365 10.319101 10.411178 10.397482
256  9.326967  9.524859  9.430760  9.409109
257 10.343032 10.415892 10.394121 10.436642
261 10.441500 10.530869 10.627649 10.609921
262  8.479491  9.151015  8.457443  8.461892
265 10.294042 10.215191 10.361229 10.407802
269 10.522531 10.525595 10.421537 10.389611
270 10.461359 10.330453 10.370518 10.315829
272 10.055436 10.099712  9.980310  9.886240
274  8.691986  9.350276  8.921324  9.160730
277 10.570111 10.604156 10.493965 10.445637
278 10.159718 10.174125 10.296003 10.287014
280  9.181323  9.812359  9.615005  9.691840
283 10.251359 10.016191 10.032848  9.811592
285 10.000886  9.942804 10.066881 10.015655
288 10.581546 10.639694 10.498719 10.440273
295 10.654385  7.775276  7.955776  8.072779
302  9.781941  9.843313  9.871016  9.824553
306  9.459619  9.814820  9.482198  9.573176
308  9.849348  9.679844  9.859588 10.015521
310  9.024974  9.530756  9.023890  9.084324
311 10.281684 10.166083 10.259727 10.194215
312  9.191973  7.871311  7.482682  7.922624
315 10.176602 10.056080  9.979059 10.090962
317 10.205405 10.273256 10.259762 10.321441
320  4.969813  6.866933 10.620888  6.779922
325  9.336973  9.557541  9.561631  9.695910
326 10.475963 10.532230 10.637081 10.445579
329  8.793612  9.650400  8.290544  8.504513
331 10.466127 10.440945 10.533269 10.492634
332 10.215045 10.314968  9.856972 10.020559
335 10.033770 10.286230 10.187086 10.305179
337 10.394672 10.255868 10.325384 10.302566
339 10.232144 10.417837 10.061644  9.909967
343  9.973853 10.105326 10.238924 10.168234
348  8.496990  9.251194  9.249946  9.207135
353  9.607168  9.486152  9.721006  9.526610
354  9.666308  9.606226  9.646529  9.588297
355 10.580836  6.261492  7.908387  8.303505
358 10.320717 10.434351 10.389057 10.392589
363 10.286503  9.945924  9.563670  9.599134
364  9.165448  8.712595  9.181220  9.422949
365  8.674026  9.306378  9.224440  8.912473
366  7.922624  8.352083  7.718241  8.810161
372 10.143685 10.237564  9.982068 10.091833
375  7.363280  9.303466  9.103979  9.367259
376  7.948385 10.680976  7.287561 10.674568
380 10.310285 10.320881 10.342323 10.315100
381 10.053372 10.096213  9.707351  9.908475
382 10.171145 10.312945 10.305814 10.352523
384  9.309733  9.135617  8.619569  9.267571
385  9.652716  9.991361  9.931103 10.136621
387 10.140416 10.380901 10.231027 10.267436
388  9.206132  9.179572  9.508591  9.219895
391  9.542876  9.660141  9.572480  9.699718
394  8.906529  9.110741  9.135832  9.208939
399  8.310169  9.984560  8.840291 10.485368
401 10.116985 10.281718  9.972454 10.075422
413  8.560253  8.393895 10.595058 10.539482
416 10.233654 10.648919 10.583271 10.605941
420 10.424808 10.333060 10.284865 10.328527
422  9.418411  9.253783  9.363748  9.415320
426  8.453614  8.970559  9.270400  9.053920
427  8.821142  8.260493  8.163086  8.487146
430  9.074521  9.319822  8.947546  8.937875
431 10.478330 10.450076 10.413193 10.462131
437 10.281821 10.417059 10.017664 10.192906
439 10.335952 10.447467 10.273291 10.217057
441 10.048151 10.395253 10.014268 10.034560
445 10.279695 10.197462 10.097120 10.153624
446 10.075633 10.185730 10.238566 10.236095
447 10.583955 10.686887 10.671789  6.133398
450  9.778094  9.722984  9.898676  9.690604
451 10.157703 10.272358  9.810495  9.894901
454  9.955036 10.159214 10.144117 10.382513
456  9.803667  9.969931  9.952801  9.868637
457 10.101149 10.300484 10.352044 10.292552
459 10.225209 10.189794 10.079581 10.121458
460 10.497891 10.639862 10.437375 10.458923
462 10.556698 10.639071 10.598034 10.491802
463  8.927712  8.862342  8.371242  9.018332
466 10.341291 10.267262 10.015342 10.143803
468  9.914872  9.775313  9.786841  9.644004
469 10.623301 10.604107 10.644281 10.617784
475  9.808902 10.061687  9.736902 10.007622
476  9.866668  9.774233  9.733648  9.657395
477 10.420852 10.349006 10.344899 10.324498
478  8.786609  9.448097  9.696402  9.270023
479 10.105081 10.054576 10.149644 10.057838
482  9.438670  9.302464  9.005037  9.056023
484 10.273429 10.566588 10.455446 10.486541
486 10.194178 10.353416 10.374335 10.269033
489  9.819725  9.722205  9.762673  9.984560
492  9.716194  9.960482  9.952611  9.975948
499  9.756379  9.879656 10.018511 10.106102
500 10.588451 10.679895 10.631592 10.684188

$coefficients
       beta0 betaGroup.2vsGroup.1      betaTime betaTimexGroup.2
2   2.341797          0.010010354  0.0000000000      0.007407775
4   2.335556         -0.011671519  0.0000000000      0.000000000
6   2.354382          0.005613270  0.0000000000      0.000000000
7   2.337384          0.000000000 -0.0038306855      0.019074065
8   2.285872          0.000000000  0.0000000000      0.000000000
12  2.158656         -0.045641436  0.0000000000      0.000000000
19  2.103645          0.000000000  0.0000000000      0.129263131
21  2.345405          0.000000000  0.0000000000     -0.080037090
22  2.292050         -0.012209275  0.0000000000      0.000000000
26  2.275946          0.000000000  0.0000000000      0.000000000
29  2.354196          0.000000000  0.0000000000     -0.181937204
30  2.349060          0.000000000  0.0000000000      0.000000000
33  2.360168          0.000000000  0.0000000000     -0.002830560
36  2.289585         -0.167368566  0.2702115806      0.000000000
37  2.240521          0.000000000  0.0060148474     -0.029436531
39  2.230413          0.000000000  0.0000000000      0.000000000
41  2.159281          0.000000000 -0.0872920433     -0.088483755
44  2.271063          0.000000000  0.0000000000      0.000000000
45  2.292566          0.012157641  0.0077690210      0.000000000
51  2.334542          0.010643798  0.0013522096      0.000000000
53  2.329939          0.000000000  0.0000000000      0.010721919
56  2.212280          0.000000000  0.0000000000      0.000000000
58  2.326190         -0.029046585  0.0000000000      0.000000000
59  2.270169          0.000000000  0.0000000000     -0.221905611
62  2.189305          0.000000000  0.0000000000      0.000000000
63  2.309683         -0.007798955  0.0000000000      0.000000000
64  2.318325          0.010155066  0.0122046031      0.000000000
68  2.335207          0.000000000  0.0000000000      0.271295577
73  2.090393          0.000000000  0.0000000000      0.052264136
74  2.348465          0.000000000  0.0000000000     -0.096688592
76  2.294314          0.016273755  0.0000000000      0.000000000
80  2.293958          0.000000000  0.0000000000      0.000000000
82  2.316036          0.000000000  0.0000000000      0.000000000
84  2.343423         -0.176945085  0.0000000000     -0.208840225
87  2.223261          0.018369321  0.0000000000      0.000000000
91  2.263194         -0.019429190  0.0000000000      0.024179735
96  2.333786         -0.023338963  0.0000000000      0.000000000
97  2.331394          0.000000000  0.0000000000      0.000000000
101 2.186048         -0.024836211  0.0000000000      0.029751923
103 2.333720          0.013177410  0.0000000000     -0.005657056
106 2.308950         -0.247454470  0.0000000000      0.000000000
107 2.312102          0.010772104  0.0000000000      0.000000000
108 2.282626          0.000000000  0.0000000000      0.000000000
109 2.212587          0.000000000 -0.0086420478      0.000000000
113 2.351826          0.003779779  0.0047808767      0.000000000
114 2.098163          0.000000000  0.0756955418      0.000000000
117 2.169646          0.064153431  0.0000000000      0.000000000
119 2.258284          0.000000000  0.0000000000      0.000000000
123 2.066719          0.000000000  0.0000000000      0.000000000
125 2.304006          0.027905819  0.0067075578     -0.009144990
128 2.290778         -0.039235719  0.0000000000      0.027919296
130 2.351365          0.000000000  0.0000000000     -0.036832907
133 2.226385         -0.045918625  0.0000000000      0.000000000
138 2.331020         -0.016284707  0.0000000000      0.024148792
139 2.337771          0.000000000  0.0000000000      0.000000000
141 2.280362         -0.031092250  0.0000000000      0.000000000
144 2.295074         -0.018512390  0.0000000000      0.000000000
153 2.017166          0.000000000  0.0000000000      0.342191983
154 2.310444          0.000000000  0.0000000000      0.000000000
157 2.270814         -0.023907050  0.0000000000      0.000000000
161 2.356714          0.000000000  0.0000000000     -0.197071091
165 2.250502          0.000000000  0.0000000000     -0.006411034
167 2.273095         -0.159464624 -0.0967627562      0.143438490
168 2.337460          0.000000000  0.0000000000     -0.047967222
170 2.359115          0.000000000  0.0000000000     -0.069170736
174 2.336769          0.000000000  0.0000000000     -0.031041758
176 2.320998          0.000000000  0.0000000000      0.007387576
178 2.103618          0.040513940  0.0000000000      0.000000000
182 2.264667          0.000000000  0.0000000000      0.051919777
183 2.273001          0.000000000  0.0000000000      0.000000000
184 2.359311         -0.003324193  0.0000000000      0.000000000
185 2.253177         -0.020315864  0.0000000000      0.000000000
187 2.253592          0.021440520  0.0000000000      0.000000000
188 2.240478          0.033197481  0.0000000000     -0.038879499
189 2.261080         -0.012466502  0.0000000000      0.000000000
190 2.304317          0.014419578  0.0000000000      0.000000000
191 2.275224          0.000000000  0.0000000000      0.000000000
192 2.336879          0.000000000  0.0000000000     -0.057671509
193 2.241121          0.000000000  0.0000000000      0.019240712
196 2.329669          0.000000000  0.0000000000      0.000000000
200 2.219348          0.000000000  0.0000000000     -0.216767435
204 2.334046          0.013481857  0.0000000000     -0.034760929
205 2.358022          0.000000000  0.0000000000      0.000000000
207 2.220629          0.000000000  0.0000000000     -0.034801221
208 2.214148          0.015551308  0.0000000000      0.000000000
211 2.345218         -0.016913897  0.0000000000     -0.077705297
216 2.301558          0.000000000  0.0000000000     -0.013138658
222 2.355703          0.000000000  0.0000000000     -0.124855341
223 2.348419          0.000000000  0.0000000000      0.000000000
224 2.329993          0.011747364  0.0000000000      0.000000000
226 2.353969         -0.015079404  0.0000000000      0.000000000
229 2.242512         -0.019548572  0.0000000000      0.000000000
230 2.302116         -0.046704060 -0.0775100714      0.134999533
233 2.314865          0.025399060  0.0000000000      0.000000000
234 2.305168          0.011597913  0.0000000000      0.000000000
236 2.221185          0.000000000  0.0000000000     -0.154215871
246 2.342462         -0.005064132  0.0000000000      0.010835739
248 2.294723          0.027782150  0.0000000000      0.000000000
249 2.333942         -0.008298254  0.0000000000      0.008909116
250 2.244985          0.000000000  0.0003497439      0.000000000
251 2.066546          0.000000000  0.0000000000      0.146409707
253 2.338827          0.008972313  0.0000000000      0.000000000
256 2.250979          0.000000000  0.0000000000     -0.020319955
257 2.335440          0.010401826  0.0000000000      0.000000000
261 2.345112          0.009970786  0.0000000000      0.000000000
262 2.186783         -0.059263795  0.0000000000      0.000000000
265 2.325895          0.000000000 -0.0204965733      0.043283727
269 2.352176          0.000000000  0.0000000000     -0.009363480
270 2.291363          0.041725127  0.0000000000      0.042187769
272 2.314875          0.000000000  0.0000000000     -0.037630143
274 2.249382         -0.023338886  0.0000000000      0.000000000
277 2.358536         -0.012463470  0.0000000000      0.112247575
278 2.335491         -0.007489135  0.0000000000      0.000000000
280 2.282842          0.000000000  0.0000000000     -0.082628277
283 2.321706          0.000000000  0.0000000000     -0.632567576
285 2.325466         -0.009363096  0.0000000000      0.000000000
288 2.350519          0.000000000  0.0000000000      0.000000000
295 2.174498          0.000000000  0.0000000000      0.076684329
302 2.268510          0.000000000  0.0069151203      0.000000000
306 2.280185         -0.022854605  0.0000000000      0.000000000
308 2.303475          0.000000000  0.0000000000     -0.074576855
310 2.251758         -0.040628562  0.0000000000      0.000000000
311 2.308492          0.012352269  0.0000000000      0.000000000
312 2.181409          0.000000000  0.4438222040     -0.490929811
315 2.330247         -0.023114916 -0.0105254010     -0.005886177
317 2.341120         -0.011286473  0.0000000000      0.020176668
320 2.336366          0.000000000  0.0000000000      0.000000000
325 2.218961          0.055162006  0.0000000000      0.000000000
326 2.350684          0.000000000  0.0000000000      0.006916314
329 2.207832          0.000000000  0.0000000000      0.384852274
331 2.347745          0.007794633  0.0000000000      0.000000000
332 2.321566         -0.021009795 -0.0552805594     -0.026167400
335 2.326013          0.000000000  0.0000000000      0.002877468
337 2.312174          0.022242096  0.0113615596      0.000000000
339 2.324467          0.000000000  0.0000000000     -0.050930302
343 2.310425          0.010240167  0.0000000000      0.000000000
348 2.143837          0.078183897  0.0000000000      0.000000000
353 2.281627         -0.018208738  0.0000000000      0.000000000
354 2.276038          0.000000000  0.0000000000      0.000000000
355 2.278542         -0.168965698  0.0000000000      0.110894375
358 2.330178          0.011689625  0.0016074142     -0.002635239
363 2.279141          0.000000000  0.0336361703      0.000000000
364 2.187717          0.000000000  0.0000000000      0.000000000
365 2.204511         -0.049962073  0.0000000000      0.000000000
366 1.852938          0.262200081  0.2488056915     -0.060396252
372 2.333425         -0.025228086 -0.0185919824      0.000000000
375 2.267503          0.000000000  0.0000000000     -0.261956777
376 2.030931          0.230549836  0.0000000000     -0.165834247
380 2.336422          0.000000000 -0.0021197616      0.000000000
381 2.323867         -0.020151708  0.0000000000      0.002731924
382 2.319059          0.016779728  0.0000000000     -0.002800573
384 2.148002          0.044321504  0.0143645793      0.000000000
385 2.304647          0.000000000  0.0000000000     -0.094672997
387 2.338587         -0.021270124  0.0000000000      0.000000000
388 2.145826          0.037620827 -0.0336662585      0.060050864
391 2.284723          0.000000000  0.0000000000     -0.025937466
394 2.211017          0.000000000  0.0093291357      0.002155879
399 2.262329          0.056938840  0.0000000000      0.000000000
401 2.318796          0.000000000  0.0000000000      0.000000000
413 2.117936          0.166021284  0.0000000000      0.000000000
416 2.335971          0.000000000  0.0000000000      0.000000000
420 2.327681          0.000000000  0.0000000000      0.000000000
422 2.270820         -0.026177517  0.0000000000      0.000000000
426 2.102156          0.091921682  0.0000000000      0.000000000
427 2.099022          0.000000000 -0.0442380751      0.052379819
430 2.229776          0.000000000  0.0000000000     -0.021717023
431 2.341641          0.006559980  0.0000000000      0.000000000
437 2.349603         -0.023958812  0.0000000000      0.000000000
439 2.340720          0.000000000  0.0000000000      0.000000000
441 2.321706          0.000000000 -0.0028185951     -0.039070027
445 2.337985         -0.023905437  0.0000000000      0.003037452
446 2.338509          0.000000000  0.0000000000     -0.033786589
447 2.200591          0.000000000 -0.2692458983      0.320739101
450 2.271576          0.029046232  0.0000000000     -0.037534862
451 2.315566          0.000000000  0.0000000000     -0.062238372
454 2.314196          0.017926720  0.0373635342     -0.064389240
456 2.279652          0.017394705  0.0000000000     -0.025362452
457 2.343322          0.000000000  0.0000000000     -0.055199569
459 2.327911         -0.011279188  0.0000000000      0.017055512
460 2.353048          0.000000000  0.0000000000     -0.012006743
462 2.215168          0.143847496  0.0000000000      0.000000000
463 2.190440          0.000000000  0.0000000000      0.000000000
466 2.308966          0.000000000  0.0000000000      0.014806537
468 2.278753          0.000000000  0.0000000000      0.010237597
469 2.269660          0.000000000 -0.3039652524      0.000000000
475 2.315156         -0.088887835  0.0000000000      0.000000000
476 2.279400         -0.028504787  0.0000000000      0.043703702
477 2.334437         -0.011879450  0.0000000000      0.018042798
478 2.276551          0.000000000  0.0000000000      0.005179474
479 2.307311          0.007819362  0.0000000000      0.000000000
482 2.211619          0.000000000 -0.0714245371      0.000000000
484 2.354203          0.000000000  0.0000000000     -0.128474001
486 2.340340          0.000000000  0.0000000000     -0.006693707
489 2.242110          0.000000000  0.0000000000      0.004984554
492 2.262202          0.027244192  0.0000000000      0.000000000
499 2.322810         -0.023032528  0.0000000000     -0.019529439
500 1.942419          0.297005897  0.0000000000     -0.164637788
        betaTime2 betaTime2xGroup.2     betaTime3 betaTime3xGroup.2
2    0.000000e+00     -2.508040e-03  0.000000e+00      2.507705e-04
4   -1.476805e-05      3.846941e-03  0.000000e+00     -5.373123e-04
6    0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
7    6.288913e-04     -5.131815e-03 -1.990091e-05      4.358547e-04
8    0.000000e+00     -1.142364e-02  0.000000e+00      3.158851e-03
12   0.000000e+00     -2.087899e-03  0.000000e+00      8.926128e-05
19  -2.220972e-02     -2.717821e-02  7.436130e-03      0.000000e+00
21   0.000000e+00      4.180690e-02  0.000000e+00     -7.777735e-03
22   0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
26   0.000000e+00      2.031754e-03 -2.039090e-04     -2.799653e-04
29   0.000000e+00      5.817101e-02  0.000000e+00     -5.471761e-03
30   0.000000e+00     -8.801766e-03  0.000000e+00      2.344219e-03
33  -1.455294e-03      0.000000e+00  4.908099e-04      0.000000e+00
36  -2.255356e-01      1.137957e-01  5.289663e-02     -3.317565e-02
37  -1.004002e-03      8.812754e-03  3.228588e-05     -8.075166e-04
39   0.000000e+00     -7.112108e-02  0.000000e+00      2.097658e-02
41   6.846829e-02      2.016673e-02 -1.613748e-02      0.000000e+00
44   0.000000e+00      2.910749e-03  0.000000e+00     -3.859600e-04
45  -1.829733e-03      0.000000e+00  0.000000e+00      0.000000e+00
51  -5.988209e-05      0.000000e+00  0.000000e+00      0.000000e+00
53   0.000000e+00     -1.540473e-03  0.000000e+00      4.608750e-05
56   0.000000e+00     -1.345303e-02  0.000000e+00      1.885679e-03
58   0.000000e+00      0.000000e+00  0.000000e+00      9.906734e-07
59   0.000000e+00      6.204634e-02  0.000000e+00     -4.538743e-03
62   0.000000e+00      2.412813e-03  0.000000e+00     -3.065695e-04
63   0.000000e+00     -9.245189e-04  0.000000e+00      1.264732e-04
64  -4.529248e-03      0.000000e+00  4.831407e-04      2.548497e-04
68   0.000000e+00     -2.035360e-01  0.000000e+00      4.367822e-02
73   0.000000e+00     -2.426935e-03  0.000000e+00      0.000000e+00
74   0.000000e+00      3.964833e-02  0.000000e+00     -6.707911e-03
76   0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
80   0.000000e+00      3.574035e-02 -7.777485e-03     -5.603430e-03
82   0.000000e+00     -8.674602e-03  0.000000e+00      2.678908e-03
84   0.000000e+00      8.643909e-02  0.000000e+00     -9.562452e-03
87   0.000000e+00      0.000000e+00 -5.549426e-04      0.000000e+00
91   0.000000e+00     -3.709765e-03 -5.954141e-04      1.155176e-04
96   0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
97   0.000000e+00      0.000000e+00  0.000000e+00     -6.958586e-04
101  0.000000e+00     -3.959374e-03  0.000000e+00      1.157302e-04
103  0.000000e+00      7.998220e-04  0.000000e+00     -2.368950e-05
106  0.000000e+00      0.000000e+00 -6.648076e-03      6.842863e-03
107  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
108  0.000000e+00     -4.723548e-02  0.000000e+00      1.379667e-02
109  0.000000e+00      0.000000e+00  6.696593e-04     -3.262225e-04
113 -1.631208e-03      7.028089e-04  1.690123e-04     -1.112366e-04
114 -1.163849e-02      3.426089e-03  3.538608e-04     -1.397703e-04
117  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
119  0.000000e+00     -1.183652e-01  0.000000e+00      3.802177e-02
123  0.000000e+00      8.142345e-02  0.000000e+00     -2.208847e-02
125 -8.998968e-04      0.000000e+00  2.690374e-05      0.000000e+00
128  0.000000e+00     -4.375952e-03  0.000000e+00      1.362311e-04
130  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
133  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
138  0.000000e+00     -6.546496e-03  0.000000e+00      5.562960e-04
139  0.000000e+00      6.977292e-03  0.000000e+00     -2.193495e-03
141  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
144  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
153  0.000000e+00     -1.204770e-01  0.000000e+00      1.210059e-02
154  0.000000e+00      0.000000e+00  0.000000e+00      2.296148e-04
157  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
161  0.000000e+00      5.173595e-02  0.000000e+00     -4.363623e-03
165  0.000000e+00      2.248526e-04  0.000000e+00      0.000000e+00
167  0.000000e+00     -2.211458e-02  5.081325e-03      6.748622e-04
168  0.000000e+00      2.404659e-02  0.000000e+00     -4.679606e-03
170  0.000000e+00      3.884692e-02  0.000000e+00     -7.595045e-03
174  0.000000e+00      1.718862e-02  0.000000e+00     -3.603967e-03
176  0.000000e+00     -8.921265e-04  0.000000e+00      2.512630e-05
178  8.929928e-03      0.000000e+00 -2.478723e-03      0.000000e+00
182  0.000000e+00      0.000000e+00  0.000000e+00     -3.480530e-03
183  0.000000e+00     -1.319993e-02  0.000000e+00      3.634226e-03
184  0.000000e+00     -3.701966e-03  0.000000e+00      1.013478e-03
185  0.000000e+00     -4.750001e-03  0.000000e+00      6.346608e-04
187  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
188  0.000000e+00      5.972085e-03  0.000000e+00     -1.842070e-04
189  0.000000e+00     -8.279818e-03 -3.059463e-05      2.493712e-03
190  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
191 -7.271699e-03      1.462003e-02  2.414110e-03     -4.384993e-03
192  0.000000e+00      1.789105e-02  0.000000e+00     -1.662241e-03
193  0.000000e+00     -3.368127e-03  0.000000e+00      1.071781e-04
196  0.000000e+00     -6.862791e-03  0.000000e+00      1.887346e-03
200  0.000000e+00      1.094056e-01  0.000000e+00     -2.075725e-02
204  0.000000e+00      1.975334e-02  0.000000e+00     -3.999793e-03
205 -1.837345e-05      1.026006e-04  0.000000e+00      0.000000e+00
207  0.000000e+00      3.574133e-03  0.000000e+00      0.000000e+00
208  0.000000e+00      7.834743e-03  0.000000e+00     -2.396582e-03
211  0.000000e+00      3.341583e-02  0.000000e+00     -6.142988e-03
216  0.000000e+00      1.758543e-03  0.000000e+00     -5.095556e-05
222  0.000000e+00      6.340413e-02  0.000000e+00     -1.193179e-02
223  0.000000e+00      0.000000e+00  0.000000e+00     -3.040907e-05
224  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
226  0.000000e+00     -2.745919e-02  0.000000e+00      7.501204e-03
229  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
230  4.635468e-02     -7.010494e-02 -1.000167e-02      1.374324e-02
233  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
234  0.000000e+00      0.000000e+00  0.000000e+00      1.850954e-04
236  0.000000e+00      8.815726e-02  0.000000e+00     -1.891711e-02
246  0.000000e+00     -3.032335e-03  0.000000e+00      2.674210e-04
248  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
249  0.000000e+00     -1.144911e-03  0.000000e+00      3.310536e-05
250  0.000000e+00     -2.529702e-03  0.000000e+00      3.624441e-04
251  0.000000e+00      0.000000e+00  0.000000e+00     -6.381832e-03
253  0.000000e+00      0.000000e+00  0.000000e+00     -7.468817e-07
256  0.000000e+00      2.697967e-03  0.000000e+00     -7.770173e-05
257  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
261  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
262  0.000000e+00      0.000000e+00 -3.125076e-06      5.145351e-06
265  1.402234e-02     -2.622459e-02 -3.086373e-03      5.470167e-03
269  0.000000e+00      9.437413e-04  0.000000e+00      0.000000e+00
270  0.000000e+00     -2.792704e-02  0.000000e+00      5.995333e-03
272  0.000000e+00      7.202699e-03  0.000000e+00      0.000000e+00
274  0.000000e+00      0.000000e+00  0.000000e+00     -1.065771e-03
277  0.000000e+00     -9.063530e-02  0.000000e+00      2.037494e-02
278  0.000000e+00      5.081347e-03  0.000000e+00     -1.529922e-03
280  0.000000e+00      4.369981e-02  0.000000e+00     -8.263634e-03
283  0.000000e+00      3.644830e-01  0.000000e+00     -7.091777e-02
285  0.000000e+00     -2.247618e-05  0.000000e+00      0.000000e+00
288  0.000000e+00     -6.760615e-03  0.000000e+00      1.994585e-03
295  0.000000e+00     -9.772697e-03  0.000000e+00      2.725527e-04
302  0.000000e+00      0.000000e+00 -5.347872e-04      3.440718e-04
306  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
308  0.000000e+00      1.968196e-02  0.000000e+00     -1.430411e-03
310  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
311  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
312 -3.420108e-01      3.593309e-01  8.014744e-02     -8.308145e-02
315  3.257859e-03      0.000000e+00 -3.112686e-04      8.865831e-05
317  0.000000e+00     -1.436556e-02  0.000000e+00      3.161328e-03
320  0.000000e+00      0.000000e+00  0.000000e+00     -2.486616e-05
325  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
326 -2.535752e-03      0.000000e+00  7.984695e-04     -5.126560e-04
329  6.205886e-03     -2.469353e-01 -9.309637e-04      5.050874e-02
331  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
332  3.220142e-02      3.593717e-03 -6.458416e-03     -1.020808e-04
335  0.000000e+00     -1.084921e-04 -2.010486e-04      0.000000e+00
337 -1.321630e-03     -1.270273e-02  3.662112e-05      3.433505e-03
339  0.000000e+00      0.000000e+00  0.000000e+00      2.089610e-03
343  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
348  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
353  0.000000e+00      0.000000e+00  0.000000e+00      3.186575e-05
354  8.239374e-03     -1.311510e-02 -2.611267e-03      3.829462e-03
355  0.000000e+00     -1.386324e-02  0.000000e+00      3.853045e-04
358  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
363 -2.434604e-02      1.152327e-02  5.762513e-03     -3.682529e-03
364  0.000000e+00     -7.817922e-03  0.000000e+00      9.257876e-04
365  0.000000e+00      1.674254e-02  0.000000e+00     -5.130990e-03
366 -1.246337e-01      0.000000e+00  2.684525e-02      0.000000e+00
372  1.037152e-02      0.000000e+00 -2.099125e-03      1.034253e-06
375  0.000000e+00      1.427680e-01  0.000000e+00     -2.976587e-02
376  0.000000e+00      2.424190e-02  0.000000e+00     -7.256683e-04
380  3.653389e-04     -2.284310e-04 -1.151854e-05      9.341652e-06
381  0.000000e+00      0.000000e+00  0.000000e+00     -5.261275e-06
382  0.000000e+00      4.326909e-04  0.000000e+00     -1.353388e-05
384 -2.096128e-03      0.000000e+00  6.262762e-05      0.000000e+00
385  0.000000e+00      4.753150e-02  0.000000e+00     -8.566527e-03
387  0.000000e+00     -6.872329e-03  0.000000e+00      1.833606e-03
388  1.432773e-02     -2.258083e-02 -1.588587e-03      2.416761e-03
391  0.000000e+00      3.261812e-03  0.000000e+00     -9.239821e-05
394  0.000000e+00      0.000000e+00 -6.744973e-04     -5.311519e-06
399  0.000000e+00     -1.998062e-02  0.000000e+00      2.970722e-03
401  0.000000e+00     -8.481059e-03  0.000000e+00      2.330968e-03
413  0.000000e+00      0.000000e+00 -3.542766e-03      4.915208e-03
416  0.000000e+00     -1.726242e-02  0.000000e+00      2.157489e-03
420  0.000000e+00      1.243240e-03  0.000000e+00     -1.367876e-04
422  0.000000e+00      2.840823e-03 -3.581308e-04     -4.111036e-04
426  7.202559e-03     -8.771433e-03 -1.102088e-03      1.356513e-03
427  1.428748e-02     -8.184344e-03 -1.324520e-03      2.520574e-04
430  0.000000e+00      2.917092e-03  0.000000e+00     -8.564381e-05
431  0.000000e+00      0.000000e+00  0.000000e+00     -9.963743e-05
437  0.000000e+00     -1.245433e-02  0.000000e+00      3.375870e-03
439  0.000000e+00     -1.267459e-03  0.000000e+00      1.780409e-04
441  0.000000e+00      1.143853e-02  0.000000e+00     -9.720344e-04
445  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
446  0.000000e+00      6.034122e-03  0.000000e+00      0.000000e+00
447  6.310717e-02     -6.659514e-02  0.000000e+00      0.000000e+00
450  0.000000e+00      2.282881e-02  0.000000e+00     -4.895788e-03
451  0.000000e+00      1.439382e-02  0.000000e+00     -1.143182e-03
454 -2.284535e-02      4.222136e-02  4.981350e-03     -9.143380e-03
456  0.000000e+00      1.704766e-02  0.000000e+00     -3.799227e-03
457  0.000000e+00      3.226709e-02  0.000000e+00     -6.714289e-03
459 -3.148248e-03      0.000000e+00  9.901262e-04     -1.145023e-03
460  0.000000e+00      0.000000e+00  0.000000e+00      6.305377e-04
462  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
463  0.000000e+00      0.000000e+00  0.000000e+00     -3.014296e-03
466  0.000000e+00     -4.204370e-03  0.000000e+00      4.013444e-04
468  0.000000e+00     -1.488764e-03 -1.165025e-06      4.554429e-05
469  9.780284e-02      0.000000e+00 -9.565481e-03      3.791616e-05
475  0.000000e+00      0.000000e+00  0.000000e+00      4.740341e-06
476  0.000000e+00     -1.213429e-02  0.000000e+00      1.078064e-03
477  0.000000e+00     -4.778454e-03  0.000000e+00      4.084935e-04
478  0.000000e+00      0.000000e+00  0.000000e+00     -1.238098e-05
479  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
482  4.666970e-02     -1.069698e-03 -1.055556e-02      4.689435e-05
484  0.000000e+00      6.454016e-02  0.000000e+00     -1.222901e-02
486  0.000000e+00      0.000000e+00  0.000000e+00      1.035752e-04
489  0.000000e+00     -1.353208e-04  0.000000e+00      0.000000e+00
492  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
499  0.000000e+00      9.347877e-03  0.000000e+00     -1.032723e-03
500  7.872827e-02      2.425513e-02 -2.434979e-02     -7.385983e-04
        betaTime4 betaTime4xGroup.2     betaTime5 betaTime5xGroup.2
2    0.000000e+00     -6.638292e-06  0.000000e+00      0.000000e+00
4    0.000000e+00      1.576071e-05  0.000000e+00      0.000000e+00
6    0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
7    0.000000e+00     -1.059722e-05  0.000000e+00      0.000000e+00
8    0.000000e+00     -2.735217e-04  0.000000e+00      6.739533e-06
12   0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
19  -7.226015e-04      2.509015e-04  1.880188e-05     -8.871415e-06
21   0.000000e+00      5.726180e-04  0.000000e+00     -1.314112e-05
22   0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
26   3.054044e-05      8.184540e-06 -9.203107e-07      0.000000e+00
29   0.000000e+00      1.401593e-04  0.000000e+00      0.000000e+00
30   0.000000e+00     -1.995295e-04  0.000000e+00      4.879807e-06
33  -4.901224e-05      5.838964e-06  1.295289e-06     -2.352399e-07
36  -4.490636e-03      3.021807e-03  1.107664e-04     -7.650438e-05
37   0.000000e+00      2.036301e-05  0.000000e+00      0.000000e+00
39   0.000000e+00     -1.886407e-03  0.000000e+00      4.732186e-05
41   1.368293e-03     -2.055574e-04 -3.368386e-05      7.372825e-06
44   0.000000e+00      1.102936e-05  0.000000e+00      0.000000e+00
45   1.922328e-05      0.000000e+00 -6.921420e-07      0.000000e+00
51   0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
53   0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
56   0.000000e+00     -5.530446e-05  0.000000e+00      0.000000e+00
58   0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
59   0.000000e+00      0.000000e+00  0.000000e+00      4.060934e-06
62   0.000000e+00      8.606266e-06  0.000000e+00      0.000000e+00
63   0.000000e+00     -3.665894e-06  0.000000e+00      0.000000e+00
64  -1.312253e-05     -4.199592e-05  0.000000e+00      1.306893e-06
68   0.000000e+00     -3.457811e-03  0.000000e+00      8.214997e-05
73   0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
74   0.000000e+00      4.798870e-04  0.000000e+00     -1.092641e-05
76   0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
80   1.177900e-03      1.711788e-04 -3.556862e-05      0.000000e+00
82   0.000000e+00     -2.481867e-04  0.000000e+00      6.314817e-06
84   0.000000e+00      2.627988e-04  0.000000e+00      0.000000e+00
87   7.982619e-05      0.000000e+00 -2.362199e-06      0.000000e+00
91   9.234975e-05      0.000000e+00 -2.816783e-06      0.000000e+00
96   0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
97   0.000000e+00      1.052404e-04  0.000000e+00     -3.177052e-06
101  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
103  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
106  9.773977e-04     -1.012810e-03 -2.921865e-05      3.034037e-05
107  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
108  0.000000e+00     -1.232673e-03  0.000000e+00      3.082354e-05
109 -8.969225e-05      5.579192e-05  2.600195e-06     -1.761521e-06
113 -4.544454e-06      3.403113e-06  0.000000e+00      0.000000e+00
114  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
117  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
119  0.000000e+00     -3.638347e-03  0.000000e+00      9.413278e-05
123  0.000000e+00      1.924444e-03  0.000000e+00     -4.772320e-05
125  0.000000e+00      1.608833e-05  0.000000e+00     -6.453134e-07
128  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
130  0.000000e+00      6.042790e-05  0.000000e+00     -2.406952e-06
133  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
138  0.000000e+00     -1.346990e-05 -1.314510e-09      0.000000e+00
139 -1.970704e-08      2.067763e-04  0.000000e+00     -5.310851e-06
141  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
144  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
153  0.000000e+00     -3.189134e-04  0.000000e+00      0.000000e+00
154  0.000000e+00     -3.452105e-05  0.000000e+00      1.038487e-06
157  0.000000e+00     -4.362019e-08  0.000000e+00      0.000000e+00
161  0.000000e+00      1.062116e-04  0.000000e+00      0.000000e+00
165  0.000000e+00      0.000000e+00  2.706648e-09      0.000000e+00
167 -5.572752e-04      0.000000e+00  1.469314e-05      0.000000e+00
168  0.000000e+00      3.643492e-04  0.000000e+00     -8.653028e-06
170  0.000000e+00      5.799363e-04  0.000000e+00     -1.358069e-05
174  0.000000e+00      2.912018e-04  0.000000e+00     -7.028108e-06
176  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
178  2.190033e-04     -7.721778e-06 -5.465373e-06      3.218911e-07
182  0.000000e+00      4.297892e-04  0.000000e+00     -1.202554e-05
183  0.000000e+00     -3.116591e-04  0.000000e+00      7.630299e-06
184  0.000000e+00     -8.718022e-05  0.000000e+00      2.140219e-06
185  0.000000e+00     -1.820893e-05  0.000000e+00      0.000000e+00
187  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
188 -8.540574e-06      0.000000e+00  3.594654e-07      0.000000e+00
189  1.224155e-06     -2.247799e-04  0.000000e+00      5.639360e-06
190  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
191 -2.346926e-04      4.045853e-04  6.110460e-06     -1.029732e-05
192  0.000000e+00      4.235721e-05  0.000000e+00      0.000000e+00
193  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
196  0.000000e+00     -1.659968e-04  0.000000e+00      4.135884e-06
200  0.000000e+00      1.570083e-03  0.000000e+00     -3.664971e-05
204  0.000000e+00      3.151220e-04  0.000000e+00     -7.510221e-06
205  0.000000e+00     -1.609400e-07  0.000000e+00      0.000000e+00
207  0.000000e+00      0.000000e+00  0.000000e+00     -1.537398e-07
208  0.000000e+00      2.234942e-04  0.000000e+00     -5.716344e-06
211  0.000000e+00      4.697620e-04  0.000000e+00     -1.109195e-05
216  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
222  0.000000e+00      9.008725e-04  0.000000e+00     -2.103295e-05
223  2.140914e-06      1.253810e-06 -8.877847e-08      0.000000e+00
224  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
226  0.000000e+00     -6.454745e-04  0.000000e+00      1.585941e-05
229  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
230  8.207155e-04     -1.068198e-03 -1.995561e-05      2.531984e-05
233  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
234  0.000000e+00     -2.925076e-05  0.000000e+00      8.963749e-07
236  0.000000e+00      1.564378e-03  0.000000e+00     -3.825457e-05
246  0.000000e+00     -6.635998e-06 -5.904462e-10      0.000000e+00
248  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
249  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
250  0.000000e+00     -1.075092e-05  0.000000e+00      0.000000e+00
251  0.000000e+00      7.156966e-04  0.000000e+00     -1.917331e-05
253  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
256  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
257 -1.093923e-06      0.000000e+00  4.527780e-08      0.000000e+00
261  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
262  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
265  2.542361e-04     -4.380145e-04 -6.186956e-06      1.052089e-05
269  0.000000e+00     -9.736585e-07  0.000000e+00      0.000000e+00
270  0.000000e+00     -4.826861e-04  0.000000e+00      1.159711e-05
272  0.000000e+00     -6.309396e-05  0.000000e+00      2.219831e-06
274  0.000000e+00      1.535692e-04  0.000000e+00     -4.551607e-06
277  0.000000e+00     -1.661132e-03  0.000000e+00      4.005975e-05
278  1.786906e-06      1.373736e-04 -7.443101e-08     -3.435728e-06
280  0.000000e+00      6.179455e-04  0.000000e+00     -1.431622e-05
283  0.000000e+00      5.373509e-03  0.000000e+00     -1.252365e-04
285  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
288  0.000000e+00     -1.805166e-04  0.000000e+00      4.548337e-06
295  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
302  6.739947e-05     -5.018147e-05 -1.899750e-06      1.494722e-06
306  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
308  0.000000e+00      0.000000e+00  0.000000e+00      1.282384e-06
310  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
311  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
312 -6.842495e-03      7.037956e-03  1.693497e-04     -1.735220e-04
315  8.079258e-06     -3.263641e-06  0.000000e+00      0.000000e+00
317  0.000000e+00     -2.581258e-04  0.000000e+00      6.245050e-06
320  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
325  0.000000e+00      0.000000e+00  0.000000e+00     -2.362021e-09
326 -7.461284e-05      6.461758e-05  1.905434e-06     -1.822226e-06
329  2.804403e-05     -3.927743e-03  0.000000e+00      9.266482e-05
331  0.000000e+00      0.000000e+00  0.000000e+00     -7.224445e-10
332  4.984894e-04      0.000000e+00 -1.172297e-05      0.000000e+00
335  2.903395e-05      0.000000e+00 -8.619736e-07      0.000000e+00
337  0.000000e+00     -2.930887e-04  0.000000e+00      7.167709e-06
339  0.000000e+00     -2.268019e-04  0.000000e+00      5.974981e-06
343  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
348  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
353  0.000000e+00     -1.337393e-06  0.000000e+00      0.000000e+00
354  2.468115e-04     -3.411890e-04 -6.346078e-06      8.514812e-06
355  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
358 -2.390275e-06      4.600518e-06  9.491136e-08     -1.841058e-07
363 -4.972220e-04      3.532350e-04  1.237206e-05     -9.156463e-06
364  0.000000e+00     -2.493300e-05  0.000000e+00      0.000000e+00
365  9.011810e-06      4.746426e-04 -3.776433e-07     -1.207201e-05
366 -2.265008e-03      8.749806e-05  5.605786e-05     -3.488125e-06
372  1.648905e-04      0.000000e+00 -3.921434e-06      0.000000e+00
375  0.000000e+00      2.417859e-03  0.000000e+00     -5.861713e-05
376  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
380  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
381  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
382  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
384  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
385  0.000000e+00      6.232381e-04  0.000000e+00     -1.424996e-05
387  0.000000e+00     -1.537600e-04  0.000000e+00      3.721764e-06
388  4.376693e-05     -6.572114e-05  0.000000e+00      0.000000e+00
391  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
394  8.346676e-05      0.000000e+00 -2.332665e-06      0.000000e+00
399  0.000000e+00     -8.932673e-05  0.000000e+00      0.000000e+00
401  0.000000e+00     -2.015851e-04  0.000000e+00      4.965422e-06
413  5.301884e-04     -7.224251e-04 -1.594135e-05      2.156470e-05
416  0.000000e+00     -5.987442e-05  0.000000e+00      0.000000e+00
420  0.000000e+00      0.000000e+00  0.000000e+00      1.486264e-07
422  5.293835e-05      1.219226e-05 -1.584790e-06      0.000000e+00
426  3.352093e-05     -4.140991e-05  0.000000e+00      0.000000e+00
427  3.360149e-05      0.000000e+00  0.000000e+00      0.000000e+00
430  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
431  0.000000e+00      1.550788e-05  0.000000e+00     -4.733694e-07
437  0.000000e+00     -2.886524e-04  0.000000e+00      7.067144e-06
439  0.000000e+00     -5.238387e-06  0.000000e+00      0.000000e+00
441  2.038450e-07      2.344840e-05  0.000000e+00      0.000000e+00
445  0.000000e+00     -7.249454e-06  0.000000e+00      2.937266e-07
446  0.000000e+00     -4.840544e-05  0.000000e+00      1.680011e-06
447 -6.697438e-04      6.444735e-04  2.412884e-05     -2.297219e-05
450  0.000000e+00      3.999639e-04  0.000000e+00     -9.706428e-06
451  0.000000e+00      2.711659e-05  0.000000e+00      0.000000e+00
454 -4.137198e-04      7.445991e-04  1.013305e-05     -1.801582e-05
456  0.000000e+00      3.145623e-04  0.000000e+00     -7.668216e-06
457  0.000000e+00      5.369198e-04  0.000000e+00     -1.288454e-05
459 -9.206403e-05      1.398427e-04  2.344049e-06     -3.889423e-06
460  0.000000e+00     -7.538566e-05  0.000000e+00      2.082467e-06
462 -8.215369e-07      8.188179e-07  0.000000e+00      0.000000e+00
463  0.000000e+00      4.486208e-04  0.000000e+00     -1.346142e-05
466  0.000000e+00     -1.045644e-05  0.000000e+00      0.000000e+00
468  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
469  2.494610e-04      0.000000e+00  0.000000e+00      0.000000e+00
475  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
476  0.000000e+00     -2.693236e-05  0.000000e+00      0.000000e+00
477  0.000000e+00     -9.983474e-06  0.000000e+00      0.000000e+00
478  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
479  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
482  8.940946e-04      0.000000e+00 -2.209210e-05      0.000000e+00
484  0.000000e+00      9.294555e-04  0.000000e+00     -2.177888e-05
486  0.000000e+00     -3.856828e-06  0.000000e+00      0.000000e+00
489  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
492  0.000000e+00      0.000000e+00  0.000000e+00      0.000000e+00
499  0.000000e+00      2.820429e-05  0.000000e+00      0.000000e+00
500  2.266064e-03      0.000000e+00 -5.780074e-05      0.000000e+00

$group.coeffs
    Group.1_beta0 Group.1_beta1 Group.1_beta2 Group.1_beta3 Group.1_beta4
2        2.341797  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
4        2.335556  0.0000000000 -1.476805e-05  0.000000e+00  0.000000e+00
6        2.354382  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
7        2.337384 -0.0038306855  6.288913e-04 -1.990091e-05  0.000000e+00
8        2.285872  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
12       2.158656  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
19       2.103645  0.0000000000 -2.220972e-02  7.436130e-03 -7.226015e-04
21       2.345405  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
22       2.292050  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
26       2.275946  0.0000000000  0.000000e+00 -2.039090e-04  3.054044e-05
29       2.354196  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
30       2.349060  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
33       2.360168  0.0000000000 -1.455294e-03  4.908099e-04 -4.901224e-05
36       2.289585  0.2702115806 -2.255356e-01  5.289663e-02 -4.490636e-03
37       2.240521  0.0060148474 -1.004002e-03  3.228588e-05  0.000000e+00
39       2.230413  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
41       2.159281 -0.0872920433  6.846829e-02 -1.613748e-02  1.368293e-03
44       2.271063  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
45       2.292566  0.0077690210 -1.829733e-03  0.000000e+00  1.922328e-05
51       2.334542  0.0013522096 -5.988209e-05  0.000000e+00  0.000000e+00
53       2.329939  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
56       2.212280  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
58       2.326190  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
59       2.270169  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
62       2.189305  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
63       2.309683  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
64       2.318325  0.0122046031 -4.529248e-03  4.831407e-04 -1.312253e-05
68       2.335207  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
73       2.090393  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
74       2.348465  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
76       2.294314  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
80       2.293958  0.0000000000  0.000000e+00 -7.777485e-03  1.177900e-03
82       2.316036  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
84       2.343423  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
87       2.223261  0.0000000000  0.000000e+00 -5.549426e-04  7.982619e-05
91       2.263194  0.0000000000  0.000000e+00 -5.954141e-04  9.234975e-05
96       2.333786  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
97       2.331394  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
101      2.186048  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
103      2.333720  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
106      2.308950  0.0000000000  0.000000e+00 -6.648076e-03  9.773977e-04
107      2.312102  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
108      2.282626  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
109      2.212587 -0.0086420478  0.000000e+00  6.696593e-04 -8.969225e-05
113      2.351826  0.0047808767 -1.631208e-03  1.690123e-04 -4.544454e-06
114      2.098163  0.0756955418 -1.163849e-02  3.538608e-04  0.000000e+00
117      2.169646  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
119      2.258284  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
123      2.066719  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
125      2.304006  0.0067075578 -8.998968e-04  2.690374e-05  0.000000e+00
128      2.290778  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
130      2.351365  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
133      2.226385  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
138      2.331020  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
139      2.337771  0.0000000000  0.000000e+00  0.000000e+00 -1.970704e-08
141      2.280362  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
144      2.295074  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
153      2.017166  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
154      2.310444  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
157      2.270814  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
161      2.356714  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
165      2.250502  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
167      2.273095 -0.0967627562  0.000000e+00  5.081325e-03 -5.572752e-04
168      2.337460  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
170      2.359115  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
174      2.336769  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
176      2.320998  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
178      2.103618  0.0000000000  8.929928e-03 -2.478723e-03  2.190033e-04
182      2.264667  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
183      2.273001  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
184      2.359311  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
185      2.253177  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
187      2.253592  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
188      2.240478  0.0000000000  0.000000e+00  0.000000e+00 -8.540574e-06
189      2.261080  0.0000000000  0.000000e+00 -3.059463e-05  1.224155e-06
190      2.304317  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
191      2.275224  0.0000000000 -7.271699e-03  2.414110e-03 -2.346926e-04
192      2.336879  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
193      2.241121  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
196      2.329669  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
200      2.219348  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
204      2.334046  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
205      2.358022  0.0000000000 -1.837345e-05  0.000000e+00  0.000000e+00
207      2.220629  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
208      2.214148  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
211      2.345218  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
216      2.301558  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
222      2.355703  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
223      2.348419  0.0000000000  0.000000e+00  0.000000e+00  2.140914e-06
224      2.329993  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
226      2.353969  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
229      2.242512  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
230      2.302116 -0.0775100714  4.635468e-02 -1.000167e-02  8.207155e-04
233      2.314865  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
234      2.305168  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
236      2.221185  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
246      2.342462  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
248      2.294723  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
249      2.333942  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
250      2.244985  0.0003497439  0.000000e+00  0.000000e+00  0.000000e+00
251      2.066546  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
253      2.338827  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
256      2.250979  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
257      2.335440  0.0000000000  0.000000e+00  0.000000e+00 -1.093923e-06
261      2.345112  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
262      2.186783  0.0000000000  0.000000e+00 -3.125076e-06  0.000000e+00
265      2.325895 -0.0204965733  1.402234e-02 -3.086373e-03  2.542361e-04
269      2.352176  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
270      2.291363  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
272      2.314875  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
274      2.249382  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
277      2.358536  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
278      2.335491  0.0000000000  0.000000e+00  0.000000e+00  1.786906e-06
280      2.282842  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
283      2.321706  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
285      2.325466  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
288      2.350519  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
295      2.174498  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
302      2.268510  0.0069151203  0.000000e+00 -5.347872e-04  6.739947e-05
306      2.280185  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
308      2.303475  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
310      2.251758  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
311      2.308492  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
312      2.181409  0.4438222040 -3.420108e-01  8.014744e-02 -6.842495e-03
315      2.330247 -0.0105254010  3.257859e-03 -3.112686e-04  8.079258e-06
317      2.341120  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
320      2.336366  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
325      2.218961  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
326      2.350684  0.0000000000 -2.535752e-03  7.984695e-04 -7.461284e-05
329      2.207832  0.0000000000  6.205886e-03 -9.309637e-04  2.804403e-05
331      2.347745  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
332      2.321566 -0.0552805594  3.220142e-02 -6.458416e-03  4.984894e-04
335      2.326013  0.0000000000  0.000000e+00 -2.010486e-04  2.903395e-05
337      2.312174  0.0113615596 -1.321630e-03  3.662112e-05  0.000000e+00
339      2.324467  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
343      2.310425  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
348      2.143837  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
353      2.281627  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
354      2.276038  0.0000000000  8.239374e-03 -2.611267e-03  2.468115e-04
355      2.278542  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
358      2.330178  0.0016074142  0.000000e+00  0.000000e+00 -2.390275e-06
363      2.279141  0.0336361703 -2.434604e-02  5.762513e-03 -4.972220e-04
364      2.187717  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
365      2.204511  0.0000000000  0.000000e+00  0.000000e+00  9.011810e-06
366      1.852938  0.2488056915 -1.246337e-01  2.684525e-02 -2.265008e-03
372      2.333425 -0.0185919824  1.037152e-02 -2.099125e-03  1.648905e-04
375      2.267503  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
376      2.030931  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
380      2.336422 -0.0021197616  3.653389e-04 -1.151854e-05  0.000000e+00
381      2.323867  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
382      2.319059  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
384      2.148002  0.0143645793 -2.096128e-03  6.262762e-05  0.000000e+00
385      2.304647  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
387      2.338587  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
388      2.145826 -0.0336662585  1.432773e-02 -1.588587e-03  4.376693e-05
391      2.284723  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
394      2.211017  0.0093291357  0.000000e+00 -6.744973e-04  8.346676e-05
399      2.262329  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
401      2.318796  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
413      2.117936  0.0000000000  0.000000e+00 -3.542766e-03  5.301884e-04
416      2.335971  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
420      2.327681  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
422      2.270820  0.0000000000  0.000000e+00 -3.581308e-04  5.293835e-05
426      2.102156  0.0000000000  7.202559e-03 -1.102088e-03  3.352093e-05
427      2.099022 -0.0442380751  1.428748e-02 -1.324520e-03  3.360149e-05
430      2.229776  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
431      2.341641  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
437      2.349603  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
439      2.340720  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
441      2.321706 -0.0028185951  0.000000e+00  0.000000e+00  2.038450e-07
445      2.337985  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
446      2.338509  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
447      2.200591 -0.2692458983  6.310717e-02  0.000000e+00 -6.697438e-04
450      2.271576  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
451      2.315566  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
454      2.314196  0.0373635342 -2.284535e-02  4.981350e-03 -4.137198e-04
456      2.279652  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
457      2.343322  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
459      2.327911  0.0000000000 -3.148248e-03  9.901262e-04 -9.206403e-05
460      2.353048  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
462      2.215168  0.0000000000  0.000000e+00  0.000000e+00 -8.215369e-07
463      2.190440  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
466      2.308966  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
468      2.278753  0.0000000000  0.000000e+00 -1.165025e-06  0.000000e+00
469      2.269660 -0.3039652524  9.780284e-02 -9.565481e-03  2.494610e-04
475      2.315156  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
476      2.279400  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
477      2.334437  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
478      2.276551  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
479      2.307311  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
482      2.211619 -0.0714245371  4.666970e-02 -1.055556e-02  8.940946e-04
484      2.354203  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
486      2.340340  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
489      2.242110  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
492      2.262202  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
499      2.322810  0.0000000000  0.000000e+00  0.000000e+00  0.000000e+00
500      1.942419  0.0000000000  7.872827e-02 -2.434979e-02  2.266064e-03
    Group.1_beta5 Group.2_beta0 Group.2_beta1 Group.2_beta2 Group.2_beta3
2    0.000000e+00      2.351808  0.0074077754 -2.508040e-03  2.507705e-04
4    0.000000e+00      2.323884  0.0000000000  3.832173e-03 -5.373123e-04
6    0.000000e+00      2.359995  0.0000000000  0.000000e+00  0.000000e+00
7    0.000000e+00      2.337384  0.0152433798 -4.502924e-03  4.159538e-04
8    0.000000e+00      2.285872  0.0000000000 -1.142364e-02  3.158851e-03
12   0.000000e+00      2.113015  0.0000000000 -2.087899e-03  8.926128e-05
19   1.880188e-05      2.103645  0.1292631312 -4.938793e-02  7.436130e-03
21   0.000000e+00      2.345405 -0.0800370903  4.180690e-02 -7.777735e-03
22   0.000000e+00      2.279841  0.0000000000  0.000000e+00  0.000000e+00
26  -9.203107e-07      2.275946  0.0000000000  2.031754e-03 -4.838743e-04
29   0.000000e+00      2.354196 -0.1819372035  5.817101e-02 -5.471761e-03
30   0.000000e+00      2.349060  0.0000000000 -8.801766e-03  2.344219e-03
33   1.295289e-06      2.360168 -0.0028305598 -1.455294e-03  4.908099e-04
36   1.107664e-04      2.122217  0.2702115806 -1.117398e-01  1.972098e-02
37   0.000000e+00      2.240521 -0.0234216837  7.808752e-03 -7.752307e-04
39   0.000000e+00      2.230413  0.0000000000 -7.112108e-02  2.097658e-02
41  -3.368386e-05      2.159281 -0.1757757986  8.863502e-02 -1.613748e-02
44   0.000000e+00      2.271063  0.0000000000  2.910749e-03 -3.859600e-04
45  -6.921420e-07      2.304724  0.0077690210 -1.829733e-03  0.000000e+00
51   0.000000e+00      2.345186  0.0013522096 -5.988209e-05  0.000000e+00
53   0.000000e+00      2.329939  0.0107219191 -1.540473e-03  4.608750e-05
56   0.000000e+00      2.212280  0.0000000000 -1.345303e-02  1.885679e-03
58   0.000000e+00      2.297143  0.0000000000  0.000000e+00  9.906734e-07
59   0.000000e+00      2.270169 -0.2219056107  6.204634e-02 -4.538743e-03
62   0.000000e+00      2.189305  0.0000000000  2.412813e-03 -3.065695e-04
63   0.000000e+00      2.301884  0.0000000000 -9.245189e-04  1.264732e-04
64   0.000000e+00      2.328480  0.0122046031 -4.529248e-03  7.379903e-04
68   0.000000e+00      2.335207  0.2712955774 -2.035360e-01  4.367822e-02
73   0.000000e+00      2.090393  0.0522641365 -2.426935e-03  0.000000e+00
74   0.000000e+00      2.348465 -0.0966885919  3.964833e-02 -6.707911e-03
76   0.000000e+00      2.310588  0.0000000000  0.000000e+00  0.000000e+00
80  -3.556862e-05      2.293958  0.0000000000  3.574035e-02 -1.338092e-02
82   0.000000e+00      2.316036  0.0000000000 -8.674602e-03  2.678908e-03
84   0.000000e+00      2.166478 -0.2088402248  8.643909e-02 -9.562452e-03
87  -2.362199e-06      2.241630  0.0000000000  0.000000e+00 -5.549426e-04
91  -2.816783e-06      2.243765  0.0241797346 -3.709765e-03 -4.798964e-04
96   0.000000e+00      2.310447  0.0000000000  0.000000e+00  0.000000e+00
97   0.000000e+00      2.331394  0.0000000000  0.000000e+00 -6.958586e-04
101  0.000000e+00      2.161212  0.0297519235 -3.959374e-03  1.157302e-04
103  0.000000e+00      2.346897 -0.0056570562  7.998220e-04 -2.368950e-05
106 -2.921865e-05      2.061496  0.0000000000  0.000000e+00  1.947872e-04
107  0.000000e+00      2.322874  0.0000000000  0.000000e+00  0.000000e+00
108  0.000000e+00      2.282626  0.0000000000 -4.723548e-02  1.379667e-02
109  2.600195e-06      2.212587 -0.0086420478  0.000000e+00  3.434368e-04
113  0.000000e+00      2.355606  0.0047808767 -9.283987e-04  5.777568e-05
114  0.000000e+00      2.098163  0.0756955418 -8.212396e-03  2.140905e-04
117  0.000000e+00      2.233800  0.0000000000  0.000000e+00  0.000000e+00
119  0.000000e+00      2.258284  0.0000000000 -1.183652e-01  3.802177e-02
123  0.000000e+00      2.066719  0.0000000000  8.142345e-02 -2.208847e-02
125  0.000000e+00      2.331912 -0.0024374322 -8.998968e-04  2.690374e-05
128  0.000000e+00      2.251542  0.0279192963 -4.375952e-03  1.362311e-04
130  0.000000e+00      2.351365 -0.0368329075  0.000000e+00  0.000000e+00
133  0.000000e+00      2.180467  0.0000000000  0.000000e+00  0.000000e+00
138 -1.314510e-09      2.314735  0.0241487919 -6.546496e-03  5.562960e-04
139  0.000000e+00      2.337771  0.0000000000  6.977292e-03 -2.193495e-03
141  0.000000e+00      2.249270  0.0000000000  0.000000e+00  0.000000e+00
144  0.000000e+00      2.276562  0.0000000000  0.000000e+00  0.000000e+00
153  0.000000e+00      2.017166  0.3421919833 -1.204770e-01  1.210059e-02
154  0.000000e+00      2.310444  0.0000000000  0.000000e+00  2.296148e-04
157  0.000000e+00      2.246906  0.0000000000  0.000000e+00  0.000000e+00
161  0.000000e+00      2.356714 -0.1970710911  5.173595e-02 -4.363623e-03
165  2.706648e-09      2.250502 -0.0064110339  2.248526e-04  0.000000e+00
167  1.469314e-05      2.113631  0.0466757339 -2.211458e-02  5.756187e-03
168  0.000000e+00      2.337460 -0.0479672218  2.404659e-02 -4.679606e-03
170  0.000000e+00      2.359115 -0.0691707358  3.884692e-02 -7.595045e-03
174  0.000000e+00      2.336769 -0.0310417580  1.718862e-02 -3.603967e-03
176  0.000000e+00      2.320998  0.0073875761 -8.921265e-04  2.512630e-05
178 -5.465373e-06      2.144132  0.0000000000  8.929928e-03 -2.478723e-03
182  0.000000e+00      2.264667  0.0519197769  0.000000e+00 -3.480530e-03
183  0.000000e+00      2.273001  0.0000000000 -1.319993e-02  3.634226e-03
184  0.000000e+00      2.355987  0.0000000000 -3.701966e-03  1.013478e-03
185  0.000000e+00      2.232861  0.0000000000 -4.750001e-03  6.346608e-04
187  0.000000e+00      2.275032  0.0000000000  0.000000e+00  0.000000e+00
188  3.594654e-07      2.273676 -0.0388794989  5.972085e-03 -1.842070e-04
189  0.000000e+00      2.248613  0.0000000000 -8.279818e-03  2.463117e-03
190  0.000000e+00      2.318737  0.0000000000  0.000000e+00  0.000000e+00
191  6.110460e-06      2.275224  0.0000000000  7.348335e-03 -1.970883e-03
192  0.000000e+00      2.336879 -0.0576715095  1.789105e-02 -1.662241e-03
193  0.000000e+00      2.241121  0.0192407117 -3.368127e-03  1.071781e-04
196  0.000000e+00      2.329669  0.0000000000 -6.862791e-03  1.887346e-03
200  0.000000e+00      2.219348 -0.2167674351  1.094056e-01 -2.075725e-02
204  0.000000e+00      2.347528 -0.0347609287  1.975334e-02 -3.999793e-03
205  0.000000e+00      2.358022  0.0000000000  8.422712e-05  0.000000e+00
207  0.000000e+00      2.220629 -0.0348012215  3.574133e-03  0.000000e+00
208  0.000000e+00      2.229700  0.0000000000  7.834743e-03 -2.396582e-03
211  0.000000e+00      2.328305 -0.0777052968  3.341583e-02 -6.142988e-03
216  0.000000e+00      2.301558 -0.0131386584  1.758543e-03 -5.095556e-05
222  0.000000e+00      2.355703 -0.1248553415  6.340413e-02 -1.193179e-02
223 -8.877847e-08      2.348419  0.0000000000  0.000000e+00 -3.040907e-05
224  0.000000e+00      2.341740  0.0000000000  0.000000e+00  0.000000e+00
226  0.000000e+00      2.338890  0.0000000000 -2.745919e-02  7.501204e-03
229  0.000000e+00      2.222964  0.0000000000  0.000000e+00  0.000000e+00
230 -1.995561e-05      2.255412  0.0574894617 -2.375027e-02  3.741576e-03
233  0.000000e+00      2.340264  0.0000000000  0.000000e+00  0.000000e+00
234  0.000000e+00      2.316766  0.0000000000  0.000000e+00  1.850954e-04
236  0.000000e+00      2.221185 -0.1542158707  8.815726e-02 -1.891711e-02
246 -5.904462e-10      2.337398  0.0108357394 -3.032335e-03  2.674210e-04
248  0.000000e+00      2.322505  0.0000000000  0.000000e+00  0.000000e+00
249  0.000000e+00      2.325644  0.0089091157 -1.144911e-03  3.310536e-05
250  0.000000e+00      2.244985  0.0003497439 -2.529702e-03  3.624441e-04
251  0.000000e+00      2.066546  0.1464097068  0.000000e+00 -6.381832e-03
253  0.000000e+00      2.347799  0.0000000000  0.000000e+00 -7.468817e-07
256  0.000000e+00      2.250979 -0.0203199553  2.697967e-03 -7.770173e-05
257  4.527780e-08      2.345842  0.0000000000  0.000000e+00  0.000000e+00
261  0.000000e+00      2.355083  0.0000000000  0.000000e+00  0.000000e+00
262  0.000000e+00      2.127520  0.0000000000  0.000000e+00  2.020274e-06
265 -6.186956e-06      2.325895  0.0227871533 -1.220225e-02  2.383794e-03
269  0.000000e+00      2.352176 -0.0093634801  9.437413e-04  0.000000e+00
270  0.000000e+00      2.333088  0.0421877694 -2.792704e-02  5.995333e-03
272  0.000000e+00      2.314875 -0.0376301430  7.202699e-03  0.000000e+00
274  0.000000e+00      2.226043  0.0000000000  0.000000e+00 -1.065771e-03
277  0.000000e+00      2.346073  0.1122475748 -9.063530e-02  2.037494e-02
278 -7.443101e-08      2.328002  0.0000000000  5.081347e-03 -1.529922e-03
280  0.000000e+00      2.282842 -0.0826282769  4.369981e-02 -8.263634e-03
283  0.000000e+00      2.321706 -0.6325675762  3.644830e-01 -7.091777e-02
285  0.000000e+00      2.316103  0.0000000000 -2.247618e-05  0.000000e+00
288  0.000000e+00      2.350519  0.0000000000 -6.760615e-03  1.994585e-03
295  0.000000e+00      2.174498  0.0766843295 -9.772697e-03  2.725527e-04
302 -1.899750e-06      2.268510  0.0069151203  0.000000e+00 -1.907154e-04
306  0.000000e+00      2.257330  0.0000000000  0.000000e+00  0.000000e+00
308  0.000000e+00      2.303475 -0.0745768548  1.968196e-02 -1.430411e-03
310  0.000000e+00      2.211130  0.0000000000  0.000000e+00  0.000000e+00
311  0.000000e+00      2.320844  0.0000000000  0.000000e+00  0.000000e+00
312  1.693497e-04      2.181409 -0.0471076075  1.732015e-02 -2.934005e-03
315  0.000000e+00      2.307132 -0.0164115781  3.257859e-03 -2.226103e-04
317  0.000000e+00      2.329834  0.0201766684 -1.436556e-02  3.161328e-03
320  0.000000e+00      2.336366  0.0000000000  0.000000e+00 -2.486616e-05
325  0.000000e+00      2.274123  0.0000000000  0.000000e+00  0.000000e+00
326  1.905434e-06      2.350684  0.0069163142 -2.535752e-03  2.858136e-04
329  0.000000e+00      2.207832  0.3848522739 -2.407294e-01  4.957777e-02
331  0.000000e+00      2.355539  0.0000000000  0.000000e+00  0.000000e+00
332 -1.172297e-05      2.300557 -0.0814479596  3.579514e-02 -6.560497e-03
335 -8.619736e-07      2.326013  0.0028774682 -1.084921e-04 -2.010486e-04
337  0.000000e+00      2.334416  0.0113615596 -1.402436e-02  3.470126e-03
339  0.000000e+00      2.324467 -0.0509303019  0.000000e+00  2.089610e-03
343  0.000000e+00      2.320665  0.0000000000  0.000000e+00  0.000000e+00
348  0.000000e+00      2.222021  0.0000000000  0.000000e+00  0.000000e+00
353  0.000000e+00      2.263418  0.0000000000  0.000000e+00  3.186575e-05
354 -6.346078e-06      2.276038  0.0000000000 -4.875723e-03  1.218195e-03
355  0.000000e+00      2.109576  0.1108943752 -1.386324e-02  3.853045e-04
358  9.491136e-08      2.341868 -0.0010278248  0.000000e+00  0.000000e+00
363  1.237206e-05      2.279141  0.0336361703 -1.282277e-02  2.079983e-03
364  0.000000e+00      2.187717  0.0000000000 -7.817922e-03  9.257876e-04
365 -3.776433e-07      2.154549  0.0000000000  1.674254e-02 -5.130990e-03
366  5.605786e-05      2.115138  0.1884094394 -1.246337e-01  2.684525e-02
372 -3.921434e-06      2.308197 -0.0185919824  1.037152e-02 -2.098091e-03
375  0.000000e+00      2.267503 -0.2619567773  1.427680e-01 -2.976587e-02
376  0.000000e+00      2.261480 -0.1658342466  2.424190e-02 -7.256683e-04
380  0.000000e+00      2.336422 -0.0021197616  1.369078e-04 -2.176888e-06
381  0.000000e+00      2.303715  0.0027319237  0.000000e+00 -5.261275e-06
382  0.000000e+00      2.335839 -0.0028005727  4.326909e-04 -1.353388e-05
384  0.000000e+00      2.192323  0.0143645793 -2.096128e-03  6.262762e-05
385  0.000000e+00      2.304647 -0.0946729966  4.753150e-02 -8.566527e-03
387  0.000000e+00      2.317317  0.0000000000 -6.872329e-03  1.833606e-03
388  0.000000e+00      2.183447  0.0263846051 -8.253102e-03  8.281749e-04
391  0.000000e+00      2.284723 -0.0259374656  3.261812e-03 -9.239821e-05
394 -2.332665e-06      2.211017  0.0114850142  0.000000e+00 -6.798088e-04
399  0.000000e+00      2.319268  0.0000000000 -1.998062e-02  2.970722e-03
401  0.000000e+00      2.318796  0.0000000000 -8.481059e-03  2.330968e-03
413 -1.594135e-05      2.283957  0.0000000000  0.000000e+00  1.372442e-03
416  0.000000e+00      2.335971  0.0000000000 -1.726242e-02  2.157489e-03
420  0.000000e+00      2.327681  0.0000000000  1.243240e-03 -1.367876e-04
422 -1.584790e-06      2.244643  0.0000000000  2.840823e-03 -7.692344e-04
426  0.000000e+00      2.194078  0.0000000000 -1.568874e-03  2.544257e-04
427  0.000000e+00      2.099022  0.0081417441  6.103135e-03 -1.072463e-03
430  0.000000e+00      2.229776 -0.0217170227  2.917092e-03 -8.564381e-05
431  0.000000e+00      2.348201  0.0000000000  0.000000e+00 -9.963743e-05
437  0.000000e+00      2.325644  0.0000000000 -1.245433e-02  3.375870e-03
439  0.000000e+00      2.340720  0.0000000000 -1.267459e-03  1.780409e-04
441  0.000000e+00      2.321706 -0.0418886223  1.143853e-02 -9.720344e-04
445  0.000000e+00      2.314079  0.0030374518  0.000000e+00  0.000000e+00
446  0.000000e+00      2.338509 -0.0337865889  6.034122e-03  0.000000e+00
447  2.412884e-05      2.200591  0.0514932023 -3.487970e-03  0.000000e+00
450  0.000000e+00      2.300622 -0.0375348623  2.282881e-02 -4.895788e-03
451  0.000000e+00      2.315566 -0.0622383715  1.439382e-02 -1.143182e-03
454  1.013305e-05      2.332122 -0.0270257054  1.937601e-02 -4.162030e-03
456  0.000000e+00      2.297047 -0.0253624521  1.704766e-02 -3.799227e-03
457  0.000000e+00      2.343322 -0.0551995687  3.226709e-02 -6.714289e-03
459  2.344049e-06      2.316632  0.0170555117 -3.148248e-03 -1.548967e-04
460  0.000000e+00      2.353048 -0.0120067426  0.000000e+00  6.305377e-04
462  0.000000e+00      2.359015  0.0000000000  0.000000e+00  0.000000e+00
463  0.000000e+00      2.190440  0.0000000000  0.000000e+00 -3.014296e-03
466  0.000000e+00      2.308966  0.0148065366 -4.204370e-03  4.013444e-04
468  0.000000e+00      2.278753  0.0102375970 -1.488764e-03  4.437926e-05
469  0.000000e+00      2.269660 -0.3039652524  9.780284e-02 -9.527565e-03
475  0.000000e+00      2.226268  0.0000000000  0.000000e+00  4.740341e-06
476  0.000000e+00      2.250895  0.0437037018 -1.213429e-02  1.078064e-03
477  0.000000e+00      2.322558  0.0180427978 -4.778454e-03  4.084935e-04
478  0.000000e+00      2.276551  0.0051794743  0.000000e+00 -1.238098e-05
479  0.000000e+00      2.315131  0.0000000000  0.000000e+00  0.000000e+00
482 -2.209210e-05      2.211619 -0.0714245371  4.560000e-02 -1.050866e-02
484  0.000000e+00      2.354203 -0.1284740007  6.454016e-02 -1.222901e-02
486  0.000000e+00      2.340340 -0.0066937069  0.000000e+00  1.035752e-04
489  0.000000e+00      2.242110  0.0049845538 -1.353208e-04  0.000000e+00
492  0.000000e+00      2.289446  0.0000000000  0.000000e+00  0.000000e+00
499  0.000000e+00      2.299778 -0.0195294389  9.347877e-03 -1.032723e-03
500 -5.780074e-05      2.239425 -0.1646377878  1.029834e-01 -2.508839e-02
    Group.2_beta4 Group.2_beta5
2   -6.638292e-06  0.000000e+00
4    1.576071e-05  0.000000e+00
6    0.000000e+00  0.000000e+00
7   -1.059722e-05  0.000000e+00
8   -2.735217e-04  6.739533e-06
12   0.000000e+00  0.000000e+00
19  -4.717000e-04  9.930467e-06
21   5.726180e-04 -1.314112e-05
22   0.000000e+00  0.000000e+00
26   3.872498e-05 -9.203107e-07
29   1.401593e-04  0.000000e+00
30  -1.995295e-04  4.879807e-06
33  -4.317327e-05  1.060050e-06
36  -1.468829e-03  3.426204e-05
37   2.036301e-05  0.000000e+00
39  -1.886407e-03  4.732186e-05
41   1.162736e-03 -2.631104e-05
44   1.102936e-05  0.000000e+00
45   1.922328e-05 -6.921420e-07
51   0.000000e+00  0.000000e+00
53   0.000000e+00  0.000000e+00
56  -5.530446e-05  0.000000e+00
58   0.000000e+00  0.000000e+00
59   0.000000e+00  4.060934e-06
62   8.606266e-06  0.000000e+00
63  -3.665894e-06  0.000000e+00
64  -5.511845e-05  1.306893e-06
68  -3.457811e-03  8.214997e-05
73   0.000000e+00  0.000000e+00
74   4.798870e-04 -1.092641e-05
76   0.000000e+00  0.000000e+00
80   1.349079e-03 -3.556862e-05
82  -2.481867e-04  6.314817e-06
84   2.627988e-04  0.000000e+00
87   7.982619e-05 -2.362199e-06
91   9.234975e-05 -2.816783e-06
96   0.000000e+00  0.000000e+00
97   1.052404e-04 -3.177052e-06
101  0.000000e+00  0.000000e+00
103  0.000000e+00  0.000000e+00
106 -3.541260e-05  1.121718e-06
107  0.000000e+00  0.000000e+00
108 -1.232673e-03  3.082354e-05
109 -3.390033e-05  8.386734e-07
113 -1.141341e-06  0.000000e+00
114  0.000000e+00  0.000000e+00
117  0.000000e+00  0.000000e+00
119 -3.638347e-03  9.413278e-05
123  1.924444e-03 -4.772320e-05
125  1.608833e-05 -6.453134e-07
128  0.000000e+00  0.000000e+00
130  6.042790e-05 -2.406952e-06
133  0.000000e+00  0.000000e+00
138 -1.346990e-05 -1.314510e-09
139  2.067566e-04 -5.310851e-06
141  0.000000e+00  0.000000e+00
144  0.000000e+00  0.000000e+00
153 -3.189134e-04  0.000000e+00
154 -3.452105e-05  1.038487e-06
157 -4.362019e-08  0.000000e+00
161  1.062116e-04  0.000000e+00
165  0.000000e+00  2.706648e-09
167 -5.572752e-04  1.469314e-05
168  3.643492e-04 -8.653028e-06
170  5.799363e-04 -1.358069e-05
174  2.912018e-04 -7.028108e-06
176  0.000000e+00  0.000000e+00
178  2.112815e-04 -5.143482e-06
182  4.297892e-04 -1.202554e-05
183 -3.116591e-04  7.630299e-06
184 -8.718022e-05  2.140219e-06
185 -1.820893e-05  0.000000e+00
187  0.000000e+00  0.000000e+00
188 -8.540574e-06  3.594654e-07
189 -2.235558e-04  5.639360e-06
190  0.000000e+00  0.000000e+00
191  1.698927e-04 -4.186858e-06
192  4.235721e-05  0.000000e+00
193  0.000000e+00  0.000000e+00
196 -1.659968e-04  4.135884e-06
200  1.570083e-03 -3.664971e-05
204  3.151220e-04 -7.510221e-06
205 -1.609400e-07  0.000000e+00
207  0.000000e+00 -1.537398e-07
208  2.234942e-04 -5.716344e-06
211  4.697620e-04 -1.109195e-05
216  0.000000e+00  0.000000e+00
222  9.008725e-04 -2.103295e-05
223  3.394724e-06 -8.877847e-08
224  0.000000e+00  0.000000e+00
226 -6.454745e-04  1.585941e-05
229  0.000000e+00  0.000000e+00
230 -2.474827e-04  5.364221e-06
233  0.000000e+00  0.000000e+00
234 -2.925076e-05  8.963749e-07
236  1.564378e-03 -3.825457e-05
246 -6.635998e-06 -5.904462e-10
248  0.000000e+00  0.000000e+00
249  0.000000e+00  0.000000e+00
250 -1.075092e-05  0.000000e+00
251  7.156966e-04 -1.917331e-05
253  0.000000e+00  0.000000e+00
256  0.000000e+00  0.000000e+00
257 -1.093923e-06  4.527780e-08
261  0.000000e+00  0.000000e+00
262  0.000000e+00  0.000000e+00
265 -1.837785e-04  4.333931e-06
269 -9.736585e-07  0.000000e+00
270 -4.826861e-04  1.159711e-05
272 -6.309396e-05  2.219831e-06
274  1.535692e-04 -4.551607e-06
277 -1.661132e-03  4.005975e-05
278  1.391605e-04 -3.510159e-06
280  6.179455e-04 -1.431622e-05
283  5.373509e-03 -1.252365e-04
285  0.000000e+00  0.000000e+00
288 -1.805166e-04  4.548337e-06
295  0.000000e+00  0.000000e+00
302  1.721800e-05 -4.050275e-07
306  0.000000e+00  0.000000e+00
308  0.000000e+00  1.282384e-06
310  0.000000e+00  0.000000e+00
311  0.000000e+00  0.000000e+00
312  1.954605e-04 -4.172325e-06
315  4.815617e-06  0.000000e+00
317 -2.581258e-04  6.245050e-06
320  0.000000e+00  0.000000e+00
325  0.000000e+00 -2.362021e-09
326 -9.995262e-06  8.320818e-08
329 -3.899699e-03  9.266482e-05
331  0.000000e+00 -7.224445e-10
332  4.984894e-04 -1.172297e-05
335  2.903395e-05 -8.619736e-07
337 -2.930887e-04  7.167709e-06
339 -2.268019e-04  5.974981e-06
343  0.000000e+00  0.000000e+00
348  0.000000e+00  0.000000e+00
353 -1.337393e-06  0.000000e+00
354 -9.437757e-05  2.168734e-06
355  0.000000e+00  0.000000e+00
358  2.210244e-06 -8.919448e-08
363 -1.439870e-04  3.215599e-06
364 -2.493300e-05  0.000000e+00
365  4.836544e-04 -1.244965e-05
366 -2.177510e-03  5.256973e-05
372  1.648905e-04 -3.921434e-06
375  2.417859e-03 -5.861713e-05
376  0.000000e+00  0.000000e+00
380  0.000000e+00  0.000000e+00
381  0.000000e+00  0.000000e+00
382  0.000000e+00  0.000000e+00
384  0.000000e+00  0.000000e+00
385  6.232381e-04 -1.424996e-05
387 -1.537600e-04  3.721764e-06
388 -2.195421e-05  0.000000e+00
391  0.000000e+00  0.000000e+00
394  8.346676e-05 -2.332665e-06
399 -8.932673e-05  0.000000e+00
401 -2.015851e-04  4.965422e-06
413 -1.922367e-04  5.623342e-06
416 -5.987442e-05  0.000000e+00
420  0.000000e+00  1.486264e-07
422  6.513062e-05 -1.584790e-06
426 -7.888981e-06  0.000000e+00
427  3.360149e-05  0.000000e+00
430  0.000000e+00  0.000000e+00
431  1.550788e-05 -4.733694e-07
437 -2.886524e-04  7.067144e-06
439 -5.238387e-06  0.000000e+00
441  2.365225e-05  0.000000e+00
445 -7.249454e-06  2.937266e-07
446 -4.840544e-05  1.680011e-06
447 -2.527030e-05  1.156655e-06
450  3.999639e-04 -9.706428e-06
451  2.711659e-05  0.000000e+00
454  3.308793e-04 -7.882768e-06
456  3.145623e-04 -7.668216e-06
457  5.369198e-04 -1.288454e-05
459  4.777868e-05 -1.545374e-06
460 -7.538566e-05  2.082467e-06
462 -2.719023e-09  0.000000e+00
463  4.486208e-04 -1.346142e-05
466 -1.045644e-05  0.000000e+00
468  0.000000e+00  0.000000e+00
469  2.494610e-04  0.000000e+00
475  0.000000e+00  0.000000e+00
476 -2.693236e-05  0.000000e+00
477 -9.983474e-06  0.000000e+00
478  0.000000e+00  0.000000e+00
479  0.000000e+00  0.000000e+00
482  8.940946e-04 -2.209210e-05
484  9.294555e-04 -2.177888e-05
486 -3.856828e-06  0.000000e+00
489  0.000000e+00  0.000000e+00
492  0.000000e+00  0.000000e+00
499  2.820429e-05  0.000000e+00
500  2.266064e-03 -5.780074e-05

$sig.pvalues
         p-value R-squared p.valor_beta0 p.valor_Group.2vsGroup.1
2   1.087306e-10 0.5802967 6.583567e-101             2.398572e-03
4   1.132691e-18 0.7003170  3.952766e-92             4.081439e-03
6   1.909168e-09 0.4505929 2.384086e-121             3.314073e-07
7   2.606482e-05 0.4644825  1.057008e-82                       NA
8   2.033452e-07 0.4730113  6.395827e-85                       NA
12  6.710574e-07 0.4223760  3.985691e-62             4.447240e-02
19  6.587957e-09 0.5904256  2.774303e-51                       NA
21  1.462677e-24 0.7522723  1.813829e-95                       NA
22  1.172877e-06 0.3490202 5.509680e-102             1.528055e-05
26  9.477216e-11 0.5994875  2.049125e-91                       NA
29  2.404720e-05 0.3747031  5.306619e-60                       NA
30  5.333917e-14 0.6246226  4.864125e-93                       NA
33  1.937287e-09 0.5886212  2.329276e-95                       NA
36  2.548636e-04 0.4827779  2.194548e-32             2.558698e-02
37  1.497205e-06 0.5101934  8.067588e-75                       NA
39  4.094991e-39 0.8141603  8.150424e-72                       NA
41  3.442332e-11 0.6516805  3.286721e-55                       NA
44  4.644136e-08 0.4675632  1.883739e-90                       NA
45  1.890004e-08 0.5261527  2.562098e-86             1.496383e-06
51  6.687046e-05 0.3423568  3.414546e-89             3.159796e-04
53  3.164517e-06 0.4020894  1.370873e-96                       NA
56  3.924022e-13 0.5873677  2.825281e-70                       NA
58  2.293394e-12 0.5545396  1.139662e-92             4.616674e-09
59  5.626899e-07 0.4444770  5.472469e-56                       NA
62  6.928985e-06 0.3886499  2.125768e-88                       NA
63  3.449106e-08 0.4965614  1.358404e-98             2.359382e-02
64  6.822712e-06 0.5082283  2.535659e-77             1.526902e-02
68  1.121894e-72 0.8965481  1.505568e-80                       NA
73  5.276439e-09 0.4448415  9.078145e-50                       NA
74  8.643695e-49 0.8548262  6.514044e-87                       NA
76  5.763162e-05 0.2686735  7.834940e-93             2.230565e-04
80  2.086595e-03 0.3272958  1.212411e-37                       NA
82  3.320604e-04 0.3367025  3.940645e-89                       NA
84  4.209087e-08 0.5002984  4.096170e-45             3.306266e-02
87  7.901461e-04 0.3162688  9.654193e-71             1.527376e-02
91  4.918017e-05 0.4547889  4.308853e-72             3.973712e-02
96  1.920705e-07 0.3806349  2.727222e-91             4.856437e-06
97  7.594561e-06 0.3844383  2.219318e-90                       NA
101 1.756129e-05 0.3977021  5.437008e-78             3.582055e-02
103 9.172818e-05 0.3660317 1.231964e-100             3.774668e-04
106 2.173628e-02 0.3051577  5.078794e-31             1.082711e-02
107 6.380580e-07 0.3599604 5.906316e-105             1.032314e-05
108 4.406922e-31 0.7820623  1.139199e-76                       NA
109 1.303200e-04 0.4352393  6.032608e-75                       NA
113 3.818884e-08 0.5753962  1.456426e-90             5.630994e-02
114 1.095390e-02 0.2569838  3.221325e-36                       NA
117 2.185355e-06 0.3294446  1.456535e-68             2.300286e-05
119 6.940830e-05 0.3449078  1.025962e-47                       NA
123 6.237114e-12 0.5990869  6.685620e-48                       NA
125 8.455417e-04 0.3925038  2.459827e-72             1.971821e-04
128 5.469787e-04 0.3250873  7.879918e-77             3.935973e-03
130 1.089805e-07 0.4441778  2.258026e-63                       NA
133 3.207215e-11 0.4998579  3.734988e-82             3.905342e-08
138 3.680832e-04 0.3880783  9.296441e-87             7.038935e-03
139 3.089897e-08 0.5196737  1.735247e-97                       NA
141 9.481178e-06 0.3081086  2.701785e-82             6.195591e-05
144 2.046865e-09 0.4498673  4.448785e-98             3.443686e-07
153 5.867239e-06 0.4203062  1.320136e-43                       NA
154 1.433636e-04 0.3264334 1.741135e-102                       NA
157 1.428263e-08 0.4567725  1.341530e-88             1.064614e-05
161 1.473765e-18 0.6943327  7.012518e-64                       NA
165 7.655062e-05 0.3396680  6.923936e-80                       NA
167 1.003808e-02 0.3404916  2.095549e-33             3.798137e-02
168 1.075842e-16 0.6781105  5.384577e-95                       NA
170 7.121367e-08 0.5068689  2.353158e-92                       NA
174 4.083134e-09 0.5444061  4.996114e-95                       NA
176 2.634603e-06 0.4052398  1.230318e-98                       NA
178 2.257097e-09 0.5864580  9.392399e-65             4.788939e-06
182 7.818318e-06 0.4045600  4.007354e-68                       NA
183 1.004146e-07 0.4804340  1.101189e-83                       NA
184 1.162992e-31 0.7947148 5.511265e-110             6.524432e-02
185 7.465726e-11 0.5659369  8.423502e-76             8.958369e-02
187 9.773219e-06 0.3058367  5.089844e-89             6.326788e-05
188 9.370282e-05 0.4188839  1.600558e-64             5.392525e-02
189 2.865172e-07 0.5330533  9.968191e-77             9.116717e-02
190 2.390025e-10 0.4768990 6.587244e-104             1.089071e-07
191 2.631436e-08 0.5766483  3.374311e-69                       NA
192 4.337087e-04 0.3295588  5.022148e-77                       NA
193 2.717140e-03 0.2514779  5.851304e-80                       NA
196 6.029771e-08 0.4885776  4.120172e-92                       NA
200 1.752679e-08 0.5226623  1.699523e-64                       NA
204 8.809952e-04 0.3686122  5.781215e-93             3.404985e-03
205 1.630408e-05 0.3718844 1.259075e-108                       NA
207 9.766820e-11 0.5403040  1.335303e-75                       NA
208 1.866981e-06 0.4630252  3.139405e-80             9.457659e-02
211 4.752461e-57 0.8776246  1.577507e-83             3.253173e-02
216 2.859224e-09 0.5036193  7.423034e-95                       NA
222 2.579057e-10 0.5650904  4.374814e-79                       NA
223 1.776647e-04 0.3521072 9.407799e-108                       NA
224 2.895078e-08 0.4106030 1.647375e-105             1.552456e-06
226 3.946679e-63 0.8828941  3.439712e-82             9.085898e-02
229 1.942324e-06 0.3398095  3.430324e-92             2.125712e-05
230 2.908012e-02 0.3857338  7.145378e-55             4.219702e-03
233 5.538579e-10 0.4653607  9.387248e-93             1.697174e-07
234 1.088131e-05 0.4087036  3.771491e-94             4.441922e-03
236 5.012917e-07 0.4775647  9.939046e-68                       NA
246 2.128763e-04 0.4013172 1.067037e-101             3.937469e-02
248 6.936542e-07 0.3573739  1.318153e-86             1.089141e-05
249 3.266763e-04 0.3377275  6.873924e-98             4.354185e-02
250 1.716032e-11 0.5781045  7.407020e-94                       NA
251 1.508604e-13 0.5943065  2.927066e-49                       NA
253 3.106956e-17 0.6387098 7.286269e-117             2.149968e-10
256 7.999123e-07 0.4264101  2.018129e-83                       NA
257 1.469246e-09 0.5110817 9.071246e-103             1.537743e-07
261 1.334965e-06 0.3462469 3.848071e-106             1.662351e-05
262 2.963466e-06 0.3981874  9.000946e-70             4.011080e-06
265 9.595636e-03 0.3994809  1.175179e-78                       NA
269 1.000803e-17 0.6615049 4.149498e-104                       NA
270 3.292520e-25 0.7661271  6.046604e-83             2.775879e-06
272 2.810839e-18 0.6824064  2.100966e-88                       NA
274 4.662099e-08 0.4881789  9.395810e-72             8.749582e-02
277 7.278337e-69 0.8952631  1.476010e-89             2.560381e-02
278 1.040180e-03 0.3891807  1.281253e-87             6.642813e-02
280 1.520089e-05 0.4257679  3.149657e-82                       NA
283 4.960825e-05 0.3783579  1.408038e-52                       NA
285 4.094761e-14 0.5892684 6.441800e-107             1.131894e-05
288 1.541177e-14 0.6329298 1.377186e-103                       NA
295 7.486449e-10 0.5167800  1.002627e-59                       NA
302 1.455618e-03 0.3808794  2.050700e-78                       NA
306 5.998785e-07 0.3610902  1.934566e-90             9.925198e-06
308 2.573276e-14 0.6249665  5.444448e-79                       NA
310 4.517520e-12 0.5210169  1.709846e-85             1.498347e-08
311 1.170666e-06 0.3489080 7.616542e-102             1.526190e-05
312 7.269071e-03 0.4104534  1.576388e-36                       NA
315 9.176695e-39 0.8436189  5.357523e-74             2.656059e-04
317 1.814317e-07 0.5182668  8.218041e-96             3.949960e-03
320 6.172642e-08 0.3884522  3.186757e-59                       NA
325 3.736645e-22 0.6978909  4.288247e-85             1.256349e-12
326 5.450156e-04 0.4279424  3.569751e-90                       NA
329 8.826596e-05 0.4622421  6.984777e-50                       NA
331 1.219794e-08 0.4588103 1.789885e-113             3.767245e-07
332 5.317205e-45 0.8658863  4.039526e-65             2.815020e-02
335 1.742305e-03 0.3240836  3.057231e-89                       NA
337 3.731174e-03 0.3797047  4.647363e-68             1.107182e-02
339 2.814776e-76 0.8971318  7.093910e-86                       NA
343 2.501677e-05 0.2868175 1.005179e-102             1.222662e-04
348 1.798334e-13 0.5481405  5.973538e-73             3.380581e-09
353 2.520034e-05 0.3638074  1.223638e-91             1.038602e-04
354 1.183203e-06 0.5337012  1.045545e-73                       NA
355 6.058035e-06 0.4145887  2.571676e-53             1.348857e-03
358 4.278574e-06 0.4941851  3.120267e-89             7.467916e-05
363 2.081464e-03 0.4203083  1.637856e-65                       NA
364 9.005050e-07 0.4158105  1.185861e-64                       NA
365 1.610435e-03 0.3786306  6.421063e-64             3.166431e-03
366 2.416765e-04 0.4661543  1.170114e-30             1.603801e-04
372 2.506142e-28 0.7937129  1.938205e-83             1.452107e-13
375 1.332106e-20 0.7148442  1.848956e-66                       NA
376 1.066694e-03 0.3132823  2.255566e-41             5.977425e-03
380 1.841290e-06 0.4634178  3.608820e-99                       NA
381 3.697869e-04 0.3039723  2.867877e-88             3.141995e-03
382 2.544162e-16 0.6588228 3.860888e-104             3.675117e-07
384 1.355196e-06 0.4432247  1.277773e-62             1.061563e-05
385 5.696584e-07 0.4810124  7.715968e-82                       NA
387 1.310901e-25 0.7598250  1.948946e-89             5.859099e-04
388 9.588440e-15 0.7045872  2.727098e-54             3.639988e-02
391 1.155229e-28 0.7604865  3.870291e-91                       NA
394 5.625711e-08 0.5330402  6.335660e-82                       NA
399 4.054951e-06 0.4251429  1.475317e-60             4.343986e-02
401 6.761013e-09 0.5164783  5.234841e-92                       NA
413 7.348174e-08 0.5503957  1.180785e-33             1.978523e-02
416 4.863828e-08 0.4439146  4.051172e-56                       NA
420 4.643933e-06 0.3954852 2.887031e-103                       NA
422 2.803572e-03 0.3635653  4.078173e-72             2.755444e-03
426 3.264717e-06 0.4950665  2.668911e-52             1.713952e-04
427 9.528243e-06 0.4771199  7.637967e-55                       NA
430 2.137259e-05 0.3666784  9.252926e-80                       NA
431 1.994394e-03 0.2925322 3.718171e-106             2.084948e-03
437 1.284606e-57 0.8732837  1.053585e-89             1.251436e-04
439 1.565156e-08 0.4826883 1.040958e-109                       NA
441 4.894326e-05 0.4302141  2.221240e-72                       NA
445 6.412635e-07 0.4555422  1.393500e-90             1.399297e-04
446 4.418531e-46 0.8417640  4.325995e-97                       NA
447 2.674234e-07 0.5394530  1.981405e-32                       NA
450 2.338447e-06 0.4815070  6.072079e-86             4.710964e-05
451 5.095219e-38 0.8150108  1.739495e-85                       NA
454 5.785021e-03 0.4363100  2.178319e-63             4.299054e-02
456 1.080235e-03 0.3640822  1.190391e-88             2.755185e-03
457 3.094540e-04 0.3638124  8.440725e-87                       NA
459 3.190855e-06 0.5387841  2.800134e-77             1.792974e-02
460 2.074343e-11 0.5771963  6.862483e-97                       NA
462 3.670973e-05 0.3416300  2.943129e-41             9.738183e-03
463 3.707621e-06 0.3963046  7.933087e-63                       NA
466 1.721665e-06 0.4402411  3.159942e-97                       NA
468 1.351290e-04 0.3586437  3.149893e-87                       NA
469 8.857300e-05 0.3953655  1.548774e-31                       NA
475 2.537012e-10 0.4968281  5.373849e-70             4.623870e-08
476 1.235092e-03 0.3343017  1.638615e-81             3.736291e-03
477 1.718705e-05 0.4253765  3.124660e-99             1.197327e-03
478 4.003525e-05 0.3212450  1.680149e-78                       NA
479 6.252141e-07 0.3607788 4.651884e-111             1.018987e-05
482 4.526094e-03 0.3491171  1.208357e-57                       NA
484 1.924017e-75 0.8995254  2.995811e-93                       NA
486 1.600822e-05 0.3727993  9.126487e-95                       NA
489 1.117761e-05 0.3452290  7.009619e-85                       NA
492 6.745757e-06 0.3133341  7.654825e-85             4.903824e-05
499 4.200379e-07 0.4853911  2.206518e-85             3.991690e-03
500 8.777006e-03 0.3523417  6.850640e-23             2.128280e-02
    p.valor_Time p.valor_TimexGroup.2 p.valor_Time2 p.valor_Time2xGroup.2
2             NA         5.389676e-02            NA          5.365737e-02
4             NA                   NA  0.0769158929          1.986053e-09
6             NA                   NA            NA                    NA
7   0.0888882906         2.280788e-04  0.0735482344          4.457123e-03
8             NA                   NA            NA          1.174827e-03
12            NA                   NA            NA          4.648324e-03
19            NA         2.326868e-05  0.0328534646          4.977696e-04
21            NA         4.590456e-08            NA          7.544949e-06
22            NA                   NA            NA                    NA
26            NA                   NA            NA          8.442360e-05
29            NA         4.705928e-05            NA          3.325948e-04
30            NA                   NA            NA          1.729456e-04
33            NA         6.509397e-06  0.0467381404                    NA
36  0.0236729702                   NA  0.0082413234          4.500838e-03
37  0.0835798034         2.489186e-04  0.0645427599          1.884707e-03
39            NA                   NA            NA          6.050798e-13
41  0.0217899572         6.466384e-05  0.0064690424          4.489705e-04
44            NA                   NA            NA          1.253953e-04
45  0.0071790632                   NA  0.0062778299                    NA
51  0.0576026931                   NA  0.0298163972                    NA
53            NA         1.732791e-05            NA          1.778115e-04
56            NA                   NA            NA          1.004278e-07
58            NA                   NA            NA                    NA
59            NA         1.679046e-05            NA          2.476999e-04
62            NA                   NA            NA          2.303286e-03
63            NA                   NA            NA          4.705319e-02
64  0.0032282796                   NA  0.0037012255                    NA
68            NA         5.560855e-12            NA          4.945011e-13
73            NA         9.479117e-07            NA          2.094737e-07
74            NA         1.605125e-05            NA          5.403048e-03
76            NA                   NA            NA                    NA
80            NA                   NA            NA          4.254777e-03
82            NA                   NA            NA          1.875916e-03
84            NA         4.055360e-02            NA          1.305129e-02
87            NA                   NA            NA                    NA
91            NA         5.672561e-05            NA          4.247429e-05
96            NA                   NA            NA                    NA
97            NA                   NA            NA                    NA
101           NA         4.150152e-05            NA          1.673046e-04
103           NA         5.662713e-03            NA          7.849157e-03
106           NA                   NA            NA                    NA
107           NA                   NA            NA                    NA
108           NA                   NA            NA          3.876914e-11
109 0.0094487356                   NA            NA                    NA
113 0.0045681875                   NA  0.0068250835          2.816592e-02
114 0.0120037953                   NA  0.0096933190          4.212379e-02
117           NA                   NA            NA                    NA
119           NA                   NA            NA          9.797059e-05
123           NA                   NA            NA          6.848509e-04
125 0.0473325935         2.680279e-04  0.0681446356                    NA
128           NA         4.352692e-04            NA          2.142056e-04
130           NA         3.162735e-06            NA                    NA
133           NA                   NA            NA                    NA
138           NA         9.940259e-04            NA          6.860353e-03
139           NA                   NA            NA          6.319620e-06
141           NA                   NA            NA                    NA
144           NA                   NA            NA                    NA
153           NA         1.091099e-04            NA          2.644713e-04
154           NA                   NA            NA                    NA
157           NA                   NA            NA                    NA
161           NA         4.027524e-07            NA          1.224289e-04
165           NA         1.126839e-03            NA          1.219335e-02
167 0.0079798192         4.673381e-03            NA          3.197916e-03
168           NA         3.194877e-04            NA          6.219298e-03
170           NA         1.969661e-05            NA          2.826963e-04
174           NA         1.428066e-02            NA          4.448132e-02
176           NA         5.327666e-04            NA          1.059466e-02
178           NA                   NA  0.0108226808                    NA
182           NA         7.609516e-05            NA                    NA
183           NA                   NA            NA          5.047062e-04
184           NA                   NA            NA          4.403906e-05
185           NA                   NA            NA          5.010519e-03
187           NA                   NA            NA                    NA
188           NA         1.792943e-04            NA          3.105352e-04
189           NA                   NA            NA          1.044759e-02
190           NA                   NA            NA                    NA
191           NA                   NA  0.0641146209          2.186556e-03
192           NA         3.965515e-04            NA          2.574939e-03
193           NA         7.491370e-04            NA          5.312570e-04
196           NA                   NA            NA          3.603988e-03
200           NA         2.977707e-03            NA          2.435751e-02
204           NA         5.122718e-03            NA          1.411386e-02
205           NA                   NA  0.0007422436          1.067082e-02
207           NA         2.855312e-07            NA          1.264441e-05
208           NA                   NA            NA          6.698445e-02
211           NA         6.410404e-04            NA          1.981477e-02
216           NA         2.640459e-06            NA          1.029048e-04
222           NA         2.374698e-04            NA          4.591757e-03
223           NA                   NA            NA                    NA
224           NA                   NA            NA                    NA
226           NA                   NA            NA          3.912644e-08
229           NA                   NA            NA                    NA
230 0.0268870549         5.980308e-03  0.0488032977          2.884530e-02
233           NA                   NA            NA                    NA
234           NA                   NA            NA                    NA
236           NA         9.178015e-03            NA          2.735891e-02
246           NA         4.358326e-04            NA          2.877658e-03
248           NA                   NA            NA                    NA
249           NA         3.160887e-04            NA          1.409150e-03
250 0.0846188910                   NA            NA          2.137341e-07
251           NA         1.407737e-05            NA                    NA
253           NA                   NA            NA                    NA
256           NA         4.229044e-05            NA          8.727508e-04
257           NA                   NA            NA                    NA
261           NA                   NA            NA                    NA
262           NA                   NA            NA                    NA
265 0.0600195542         3.844069e-03  0.0626435354          1.108367e-02
269           NA         9.805122e-09            NA          3.893543e-06
270           NA         4.687169e-02            NA          4.515204e-02
272           NA         2.168875e-07            NA          3.646593e-05
274           NA                   NA            NA                    NA
277           NA         2.595208e-09            NA          1.399368e-11
278           NA                   NA            NA          5.038810e-03
280           NA         1.899757e-03            NA          1.382019e-02
283           NA         8.551472e-05            NA          5.838742e-04
285           NA                   NA            NA          4.334726e-04
288           NA                   NA            NA          9.778455e-07
295           NA         8.965259e-06            NA          4.560140e-04
302 0.0118953006                   NA            NA                    NA
306           NA                   NA            NA                    NA
308           NA         3.624998e-07            NA          3.064776e-05
310           NA                   NA            NA                    NA
311           NA                   NA            NA                    NA
312 0.0087905448         2.718766e-02  0.0041265242          2.170731e-02
315 0.0203977121         1.834149e-02  0.0289150665                    NA
317           NA         4.981634e-02            NA          3.410808e-02
320           NA                   NA            NA                    NA
325           NA                   NA            NA                    NA
326           NA         3.780911e-04  0.0181017495                    NA
329           NA         2.399231e-05  0.0813127255          6.117523e-05
331           NA                   NA            NA                    NA
332 0.0007264370         8.495685e-05  0.0023107042          2.107184e-04
335           NA         1.355121e-03            NA          6.961009e-03
337 0.0065357917                   NA  0.0285171538          1.205585e-03
339           NA         9.151408e-14            NA                    NA
343           NA                   NA            NA                    NA
348           NA                   NA            NA                    NA
353           NA                   NA            NA                    NA
354           NA                   NA  0.0066315953          3.835345e-04
355           NA         2.321925e-04            NA          1.346824e-03
358 0.0214611137         6.481624e-03            NA                    NA
363 0.0879855124                   NA  0.0731882031          2.020392e-02
364           NA                   NA            NA          8.006509e-03
365           NA                   NA            NA          1.877617e-02
366 0.0227952208         7.583841e-03  0.0797108467                    NA
372 0.0148409190                   NA  0.0389482289                    NA
375           NA         1.613567e-04            NA          1.916139e-03
376           NA         8.672069e-04            NA          9.949595e-04
380 0.0182714171                   NA  0.0069749007          3.633638e-05
381           NA         2.544773e-02            NA                    NA
382           NA         8.348925e-02            NA          7.063686e-02
384 0.0302732786                   NA  0.0317705983                    NA
385           NA         6.806810e-04            NA          9.882671e-03
387           NA                   NA            NA          1.255505e-02
388 0.0513750143         1.344127e-02  0.0174320939          6.918810e-03
391           NA         5.126003e-11            NA          7.626505e-08
394 0.0002659735         1.217592e-03            NA                    NA
399           NA                   NA            NA          4.603255e-06
401           NA                   NA            NA          4.596551e-04
413           NA                   NA            NA                    NA
416           NA                   NA            NA          1.019044e-03
420           NA                   NA            NA          1.860391e-04
422           NA                   NA            NA          3.308505e-02
426           NA                   NA  0.0089300453          1.738277e-02
427 0.0248309743         4.024641e-05  0.0271102204          1.978012e-04
430           NA         2.276114e-04            NA          2.622716e-03
431           NA                   NA            NA                    NA
437           NA                   NA            NA          2.453562e-05
439           NA                   NA            NA          7.991153e-06
441 0.0296270215         7.226363e-04            NA          6.273515e-03
445           NA         8.501715e-02            NA                    NA
446           NA         2.988451e-11            NA          1.868395e-07
447 0.0014732309         1.245991e-03  0.0023733086          9.374402e-03
450           NA         3.511803e-02            NA          4.987978e-02
451           NA         4.251792e-08            NA          1.607606e-04
454 0.0541823272         1.742884e-02  0.0805011349          1.925455e-02
456           NA         9.289544e-02            NA          8.539608e-02
457           NA         7.322074e-03            NA          2.029274e-02
459           NA         1.312858e-05  0.0607735847                    NA
460           NA         1.966885e-05            NA                    NA
462           NA                   NA            NA                    NA
463           NA                   NA            NA                    NA
466           NA         2.967844e-03            NA          2.084901e-02
468           NA         1.549354e-03            NA          5.401391e-03
469 0.0017206014                   NA  0.0029797771                    NA
475           NA                   NA            NA                    NA
476           NA         3.315866e-04            NA          2.498922e-03
477           NA         8.020573e-05            NA          1.370792e-03
478           NA         4.467160e-03            NA                    NA
479           NA                   NA            NA                    NA
482 0.0578040835                   NA  0.0624700253          1.493186e-02
484           NA         1.182114e-11            NA          2.582599e-08
486           NA         4.878026e-05            NA                    NA
489           NA         2.432405e-03            NA          4.601923e-02
492           NA                   NA            NA                    NA
499           NA         3.834338e-02            NA          4.219101e-03
500           NA         4.288857e-02  0.0487038956          4.256579e-02
    p.valor_Time3 p.valor_Time3xGroup.2 p.valor_Time4
2              NA          6.199302e-02            NA
4              NA          9.605137e-09            NA
6              NA                    NA            NA
7    0.0707837263          1.971314e-02            NA
8              NA          6.839609e-03            NA
12             NA          3.012210e-03            NA
19   0.0308676386                    NA  0.0320800558
21             NA          9.842526e-05            NA
22             NA                    NA            NA
26   0.0068677974          5.733147e-04  0.0079685929
29             NA          1.212605e-03            NA
30             NA          2.314531e-03            NA
33   0.0334655755                    NA  0.0265651277
36   0.0072925254          9.019453e-03  0.0071691949
37   0.0581058512          6.126608e-03            NA
39             NA          3.039693e-11            NA
41   0.0038988006                    NA  0.0032923715
44             NA          9.639226e-04            NA
45             NA                    NA  0.0068937082
51             NA                    NA            NA
53             NA          4.053025e-04            NA
56             NA          1.081397e-06            NA
58             NA          6.000501e-02            NA
59             NA          1.144215e-03            NA
62             NA          1.239371e-02            NA
63             NA          6.792672e-02            NA
64   0.0045673481          5.281598e-02  0.0051426978
68             NA          1.362679e-12            NA
73             NA                    NA            NA
74             NA          3.000387e-02            NA
76             NA                    NA            NA
80   0.0001628481          5.136740e-03  0.0001823729
82             NA          4.196910e-03            NA
84             NA          8.184023e-03            NA
87   0.0075692873                    NA  0.0104439310
91   0.0002512041          4.532171e-05  0.0001597386
96             NA                    NA            NA
97             NA          9.796188e-06            NA
101            NA          3.378237e-04            NA
103            NA          1.071661e-02            NA
106  0.0057842407          3.113384e-02  0.0070153789
107            NA                    NA            NA
108            NA          1.768939e-09            NA
109  0.0111820739          4.075202e-02  0.0105616865
113  0.0096705637          2.050284e-02  0.0114722752
114  0.0119541405          4.863461e-02            NA
117            NA                    NA            NA
119            NA          1.828445e-04            NA
123            NA          5.257055e-03            NA
125  0.0768105288                    NA            NA
128            NA          2.009947e-04            NA
130            NA                    NA            NA
133            NA                    NA            NA
138            NA          2.431026e-02            NA
139            NA          1.978467e-05  0.0956502592
141            NA                    NA            NA
144            NA                    NA            NA
153            NA          5.524741e-04            NA
154            NA          2.093950e-03            NA
157            NA                    NA            NA
161            NA          1.626795e-03            NA
165            NA                    NA            NA
167  0.0287085058          3.532664e-03  0.0561386892
168            NA          1.503819e-02            NA
170            NA          1.097264e-03            NA
174            NA          5.625297e-02            NA
176            NA          2.335831e-02            NA
178  0.0258710113                    NA  0.0400205304
182            NA          1.590805e-03            NA
183            NA          3.778479e-03            NA
184            NA          3.354344e-04            NA
185            NA          1.133951e-02            NA
187            NA                    NA            NA
188            NA          4.630931e-04  0.0600057720
189  0.0815198544          1.545632e-02  0.0910260984
190            NA                    NA            NA
191  0.0635524354          6.976587e-03  0.0652450163
192            NA          7.584501e-03            NA
193            NA          5.732994e-04            NA
196            NA          1.619987e-02            NA
200            NA          5.131342e-02            NA
204            NA          2.271579e-02            NA
205            NA                    NA            NA
207            NA                    NA            NA
208            NA          7.929671e-02            NA
211            NA          4.865089e-02            NA
216            NA          3.598170e-04            NA
222            NA          1.447405e-02            NA
223            NA          8.667733e-05  0.0011902560
224            NA                    NA            NA
226            NA          9.788637e-07            NA
229            NA                    NA            NA
230  0.0557592347          5.100697e-02  0.0580993900
233            NA                    NA            NA
234            NA          7.429131e-02            NA
236            NA          3.207274e-02            NA
246            NA          9.959294e-03            NA
248            NA                    NA            NA
249            NA          2.663603e-03            NA
250            NA          1.454558e-06            NA
251            NA          1.720333e-02            NA
253            NA          3.584992e-06            NA
256            NA          2.442629e-03            NA
257            NA                    NA  0.0613205928
261            NA                    NA            NA
262  0.0284622880          1.117613e-02            NA
265  0.0665670200          1.698741e-02  0.0685004303
269            NA                    NA            NA
270            NA          4.978434e-02            NA
272            NA                    NA            NA
274            NA          4.510111e-03            NA
277            NA          7.446719e-12            NA
278            NA          7.942604e-03  0.0948514447
280            NA          3.345308e-02            NA
283            NA          1.979883e-03            NA
285            NA                    NA            NA
288            NA          1.083224e-05            NA
295            NA          1.913456e-03            NA
302  0.0141232824          1.026135e-02  0.0194146435
306            NA                    NA            NA
308            NA          2.268252e-04            NA
310            NA                    NA            NA
311            NA                    NA            NA
312  0.0028189013          1.781786e-02  0.0021941579
315  0.0466802973          4.018232e-02  0.0582827736
317            NA          3.362061e-02            NA
320            NA          2.654635e-06            NA
325            NA                    NA            NA
326  0.0243848316          3.278638e-03  0.0313836033
329  0.0858885132          1.656976e-04  0.0893437639
331            NA                    NA            NA
332  0.0051841035          5.569667e-04  0.0085396284
335  0.0158924753                    NA  0.0190295432
337  0.0479329594          3.540427e-03            NA
339            NA          6.547833e-06            NA
343            NA                    NA            NA
348            NA                    NA            NA
353            NA          4.685966e-02            NA
354  0.0091352459          2.158044e-03  0.0115869595
355            NA          3.557707e-03            NA
358            NA                    NA  0.0771951912
363  0.0636192265          3.087404e-02  0.0582579537
364            NA          4.311375e-02            NA
365            NA          2.392091e-02  0.0348642188
366  0.0869278041                    NA  0.0802917024
372  0.0574104446          1.155914e-02  0.0700006414
375            NA          3.253955e-03            NA
376            NA          1.390477e-03            NA
380  0.0066566122          5.504640e-05            NA
381            NA          6.459747e-03            NA
382            NA          6.794215e-02            NA
384  0.0375699503                    NA            NA
385            NA          3.296522e-02            NA
387            NA          3.525097e-02            NA
388  0.0119447249          5.564657e-03  0.0105931371
391            NA          9.098087e-07            NA
394  0.0003266193          6.361236e-05  0.0005413775
399            NA          5.002421e-06            NA
401            NA          3.578734e-03            NA
413  0.0459900019          3.324162e-02  0.0474617834
416            NA          7.890150e-03            NA
420            NA          9.116877e-04            NA
422  0.0387525334          3.857800e-02  0.0422540340
426  0.0075301444          1.403905e-02  0.0072531991
427  0.0448779410          3.388958e-04  0.0586737654
430            NA          5.401004e-03            NA
431            NA          6.471461e-02            NA
437            NA          2.358985e-04            NA
439            NA          4.850305e-05            NA
441            NA          2.518845e-02  0.0205572274
445            NA                    NA            NA
446            NA                    NA            NA
447            NA                    NA  0.0030649184
450            NA          5.497568e-02            NA
451            NA          3.443662e-03            NA
454  0.0865952514          2.167440e-02  0.0859109197
456            NA          8.073372e-02            NA
457            NA          2.842194e-02            NA
459  0.0670166145          6.112174e-05  0.0775880968
460            NA          5.755360e-03            NA
462            NA                    NA  0.0079674130
463            NA          1.164981e-05            NA
466            NA          3.682953e-02            NA
468  0.0376845554          7.348777e-03            NA
469  0.0048617042          4.872954e-04  0.0063400901
475            NA          8.786655e-03            NA
476            NA          8.476957e-03            NA
477            NA          7.037079e-03            NA
478            NA          2.057039e-04            NA
479            NA                    NA            NA
482  0.0568106459          1.150360e-02  0.0510429537
484            NA          6.254559e-07            NA
486            NA          2.075277e-03            NA
489            NA                    NA            NA
492            NA                    NA            NA
499            NA          2.405523e-03            NA
500  0.0454060020          4.546034e-02  0.0463886567
    p.valor_Time4xGroup.2 p.valor_Time5 p.valor_Time5xGroup.2
2            6.683695e-02            NA                    NA
4            1.982848e-08            NA                    NA
6                      NA            NA                    NA
7            3.600823e-02            NA                    NA
8            1.664070e-02            NA          2.416148e-02
12                     NA            NA                    NA
19           3.441579e-03  0.0331751425          4.288289e-03
21           4.036916e-04            NA          7.799663e-04
22                     NA            NA                    NA
26           1.078600e-03  0.0084420919                    NA
29           2.133589e-03            NA                    NA
30           7.772488e-03            NA          1.273627e-02
33           2.547897e-04  0.0240021185          2.851879e-04
36           1.301518e-02  0.0071947698          1.535421e-02
37           1.058976e-02            NA                    NA
39           3.587457e-10            NA          1.145573e-09
41           1.251800e-03  0.0031522542          1.405665e-03
44           2.046749e-03            NA                    NA
45                     NA  0.0070546133                    NA
51                     NA            NA                    NA
53                     NA            NA                    NA
56           2.736326e-06            NA                    NA
58                     NA            NA                    NA
59                     NA            NA          2.799170e-03
62           2.206392e-02            NA                    NA
63           8.012522e-02            NA                    NA
64           3.495049e-02            NA          3.010740e-02
68           4.729510e-12            NA          9.820821e-12
73                     NA            NA                    NA
74           5.808447e-02            NA          7.573252e-02
76                     NA            NA                    NA
80           5.742573e-03  0.0001956106                    NA
82           6.913597e-03            NA          8.730496e-03
84           7.108942e-03            NA                    NA
87                     NA  0.0119882296                    NA
91                     NA  0.0001374869                    NA
96                     NA            NA                    NA
97           1.358254e-05            NA          1.588039e-05
101                    NA            NA                    NA
103                    NA            NA                    NA
106          3.406856e-02  0.0075881633          3.552901e-02
107                    NA            NA                    NA
108          1.861699e-08            NA          5.539609e-08
109          2.586334e-02  0.0103787602          2.179833e-02
113          1.927720e-02            NA                    NA
114                    NA            NA                    NA
117                    NA            NA                    NA
119          2.601150e-04            NA          3.078354e-04
123          1.283294e-02            NA          1.835299e-02
125          8.019989e-04            NA          8.692665e-04
128                    NA            NA                    NA
130          9.115999e-04            NA          1.119075e-03
133                    NA            NA                    NA
138          4.196711e-02  0.0767038467                    NA
139          3.904894e-05            NA          5.381822e-05
141                    NA            NA                    NA
144                    NA            NA                    NA
153          8.047695e-04            NA                    NA
154          2.659063e-03            NA          2.993715e-03
157          9.859918e-02            NA                    NA
161          4.320078e-03            NA                    NA
165                    NA  0.0933756986                    NA
167                    NA  0.0749491878                    NA
168          2.127391e-02            NA          2.454430e-02
170          2.300653e-03            NA          3.256675e-03
174          6.137567e-02            NA          6.377174e-02
176                    NA            NA                    NA
178          5.653574e-02  0.0483375920          5.569030e-02
182          2.815291e-03            NA          3.554826e-03
183          1.092795e-02            NA          1.716241e-02
184          1.137346e-03            NA          1.975560e-03
185          1.606393e-02            NA                    NA
187                    NA            NA                    NA
188                    NA  0.0568124013                    NA
189          2.267670e-02            NA          2.748756e-02
190                    NA            NA                    NA
191          1.192001e-02  0.0666631648          1.495018e-02
192          1.193187e-02            NA                    NA
193                    NA            NA                    NA
196          3.108969e-02            NA          4.038233e-02
200          7.281938e-02            NA          8.508915e-02
204          2.872172e-02            NA          3.199079e-02
205          2.094188e-02            NA                    NA
207                    NA            NA          1.224872e-04
208          8.866566e-02            NA          9.371239e-02
211          6.602798e-02            NA          7.418025e-02
216                    NA            NA                    NA
222          2.436022e-02            NA          3.052434e-02
223          1.016232e-04  0.0012284856                    NA
224                    NA            NA                    NA
226          7.067709e-06            NA          1.745957e-05
229                    NA            NA                    NA
230          6.554098e-02  0.0590812863          7.302588e-02
233                    NA            NA                    NA
234          6.134976e-02            NA          5.782790e-02
236          3.176848e-02            NA          3.120839e-02
246          1.705089e-02  0.0564626803                    NA
248                    NA            NA                    NA
249                    NA            NA                    NA
250          2.954528e-06            NA                    NA
251          4.000095e-02            NA          5.476369e-02
253                    NA            NA                    NA
256                    NA            NA                    NA
257                    NA  0.0622007273                    NA
261                    NA            NA                    NA
262                    NA            NA                    NA
265          2.075520e-02  0.0694815964          2.271682e-02
269          6.732377e-05            NA                    NA
270          5.469633e-02            NA          5.773752e-02
272          7.004583e-04            NA          9.588974e-04
274          6.340102e-03            NA          7.306865e-03
277          9.764423e-12            NA          1.263829e-11
278          1.275191e-02  0.0939285632          1.627714e-02
280          5.271886e-02            NA          6.484259e-02
283          4.029745e-03            NA          5.659095e-03
285                    NA            NA                    NA
288          4.133905e-05            NA          7.482991e-05
295                    NA            NA                    NA
302          1.597474e-02  0.0224687705          1.880413e-02
306                    NA            NA                    NA
308                    NA            NA          6.798800e-04
310                    NA            NA                    NA
311                    NA            NA                    NA
312          1.561477e-02  0.0019425967          1.466941e-02
315          4.716562e-02            NA                    NA
317          3.494534e-02            NA          3.598497e-02
320                    NA            NA                    NA
325                    NA            NA          6.370077e-02
326          4.811781e-03  0.0356683821          5.676183e-03
329          3.331313e-04            NA          4.785410e-04
331                    NA            NA          1.665883e-02
332                    NA  0.0109097360                    NA
335                    NA  0.0204998795                    NA
337          7.182062e-03            NA          1.008324e-02
339          1.127277e-04            NA          3.346743e-04
343                    NA            NA                    NA
348                    NA            NA                    NA
353          4.355063e-02            NA                    NA
354          5.521166e-03  0.0130390814          8.307365e-03
355                    NA            NA                    NA
358          1.459176e-02  0.0822125963          1.552128e-02
363          3.728395e-02  0.0560773090          4.043977e-02
364          7.600413e-02            NA                    NA
365          2.954635e-02  0.0333510824          3.305099e-02
366          4.325143e-02  0.0758748321          4.602248e-02
372                    NA  0.0767749157                    NA
375          3.725735e-03            NA          3.889070e-03
376                    NA            NA                    NA
380                    NA            NA                    NA
381                    NA            NA                    NA
382                    NA            NA                    NA
384                    NA            NA                    NA
385          5.839393e-02            NA          7.486652e-02
387          6.481124e-02            NA          8.466926e-02
388          5.294393e-03            NA                    NA
391                    NA            NA                    NA
394                    NA  0.0006905970                    NA
399          5.635793e-06            NA                    NA
401          9.878158e-03            NA          1.509979e-02
413          3.741441e-02  0.0484576406          3.957547e-02
416          1.611886e-02            NA                    NA
420                    NA            NA          1.984290e-03
422          4.250208e-02  0.0440238247                    NA
426          1.330717e-02            NA                    NA
427                    NA            NA                    NA
430                    NA            NA                    NA
431          5.636184e-02            NA          5.391182e-02
437          8.971927e-04            NA          1.630099e-03
439          9.431281e-05            NA                    NA
441          4.504337e-02            NA                    NA
445          3.827548e-02            NA          3.791937e-02
446          4.929525e-05            NA          9.013332e-05
447          2.312506e-02  0.0031992711          2.548783e-02
450          5.665773e-02            NA          5.734399e-02
451          9.854959e-03            NA                    NA
454          2.345117e-02  0.0849285748          2.443863e-02
456          7.894387e-02            NA          7.848893e-02
457          3.339059e-02            NA          3.599623e-02
459          1.324692e-04  0.0842081270          1.873246e-04
460          1.128974e-02            NA          1.459884e-02
462          4.494259e-02            NA                    NA
463          2.055855e-05            NA          2.614736e-05
466          4.516819e-02            NA                    NA
468                    NA            NA                    NA
469                    NA            NA                    NA
475                    NA            NA                    NA
476          1.419847e-02            NA                    NA
477          1.386431e-02            NA                    NA
478                    NA            NA                    NA
479                    NA            NA                    NA
482                    NA  0.0481298267                    NA
484          2.813731e-06            NA          5.490347e-06
486          2.907887e-03            NA                    NA
489                    NA            NA                    NA
492                    NA            NA                    NA
499          2.146839e-03            NA                    NA
500                    NA  0.0477325080                    NA

$g
[1] 197

$edesign
        Time Replicate Group.1 Group.2
G1.T1.1    0         1       1       0
G1.T2.1    0         1       1       0
G1.T6.1    0         1       1       0
G1.T3.1    0         1       1       0
G1.T4.1    2         2       1       0
G1.T5.1    2         2       1       0
G1.T1.2    2         2       1       0
G1.T2.2    2         2       1       0
G1.T6.2    4         3       1       0
G1.T5.2    4         3       1       0
G1.T1.3    4         3       1       0
G1.T2.3    6         4       1       0
G1.T6.3    6         4       1       0
G1.T3.3    6         4       1       0
G1.T4.3    9         5       1       0
G1.T5.3    9         5       1       0
G1.T1.4    9         5       1       0
G1.T2.4    9         5       1       0
G1.T6.4   24         6       1       0
G1.T3.4   24         6       1       0
G1.T4.4   24         6       1       0
G1.T5.4   24         6       1       0
G2.T1.1    0         7       0       1
G2.T2.1    0         7       0       1
G2.T6.1    0         7       0       1
G2.T3.1    0         7       0       1
G2.T4.1    2         8       0       1
G2.T5.1    2         8       0       1
G2.T1.2    2         8       0       1
G2.T2.2    2         8       0       1
G2.T6.2    4         9       0       1
G2.T3.2    4         9       0       1
G2.T4.2    4         9       0       1
G2.T5.2    4         9       0       1
G2.T1.3    6        10       0       1
G2.T2.3    6        10       0       1
G2.T6.3    6        10       0       1
G2.T3.3    6        10       0       1
G2.T4.3    9        11       0       1
G2.T5.3    9        11       0       1
G2.T1.4    9        11       0       1
G2.T2.4    9        11       0       1
G2.T6.4   24        12       0       1
G2.T3.4   24        12       0       1
G2.T4.4   24        12       0       1
G2.T5.4   24        12       0       1
endo_sig_genes$summary$Group.2vsGroup.1
  [1] 2   4   6   7   8   12  19  21  22  26  29  30  33  36  37  39  41 
 [18] 44  45  51  53  56  58  59  62  63  64  68  73  74  76  80  82  84 
 [35] 87  91  96  97  101 103 106 107 108 109 113 114 117 119 123 125 128
 [52] 130 133 138 139 141 144 153 154 157 161 165 167 168 170 174 176 178
 [69] 182 183 184 185 187 188 189 190 191 192 193 196 200 204 205 207 208
 [86] 211 216 222 223 224 226 229 230 233 234 236 246 248 249 250 251 253
[103] 256 257 261 262 265 269 270 272 274 277 278 280 283 285 288 295 302
[120] 306 308 310 311 312 315 317 320 325 326 329 331 332 335 337 339 343
[137] 348 353 354 355 358 363 364 365 366 372 375 376 380 381 382 384 385
[154] 387 388 391 394 399 401 413 416 420 422 426 427 430 431 437 439 441
[171] 445 446 447 450 451 454 456 457 459 460 462 463 466 468 469 475 476
[188] 477 478 479 482 484 486 489 492 499 500
197 Levels: 101 103 106 107 108 109 113 114 117 119 12 123 125 128 ... 97
# Add the regression curve computed for this gene to the plot

#Gene2 <- t_endo_data[rownames(t_endo_data) == "2", ]
#PlotGroups(Gene2, edesign = matrix_endo_design$edesign, repvec = final_endo_design[,2], show.fit = T, step.method = "forward", show.lines = F, dis = matrix_endo_design$dis, groups.vector = matrix_endo_design$groups.vector)

Plotting with maSigPro

# Group into 4 clusters 

#(Note: this generates an X11() error when run on Midway but when run on a local computer or cluster that allows for a pop-up window in R, it can generate plots that have show the general patterns of the clusters)

# see.genes(endo_sig_genes$sig.genes$Group.2vsGroup.1, k = 4)

# Plot the expression values without the regression curve. Unlike see.genes, this does not generate an error when running on Midway. 

# Gene 2 (declared significant by maSigPro)

Gene2 <- t_endo_data[rownames(t_endo_data) == "2", ]
PlotGroups(Gene2, edesign = final_endo_design, show.lines = F)

# Plot the expression values without the regression curve but with lines connecting the median values for each group at each timepoint
Gene2 <- t_endo_data[rownames(t_endo_data) == "2", ]
PlotGroups(Gene2, edesign = final_endo_design, show.lines = T)

# Plot the expression values with the regression curve

# Sample genes (Note: when degree = 3, use 287 and 205. When degree = 5, use 108, 205, 445)
Gene2 <- t_endo_data[rownames(t_endo_data) == "2", ]
PlotGroups(Gene2, edesign = final_endo_design, show.fit = T, dis = matrix_endo_design$dis, groups.vector = matrix_endo_design$groups.vector, show.lines = F)

# Sample genes/visualizations to compare to edge

# Gene 108 
Gene108 <- t_endo_data[rownames(t_endo_data) == "108", ]
PlotGroups(Gene108, edesign = final_endo_design, show.fit = T, dis = matrix_endo_design$dis, groups.vector = matrix_endo_design$groups.vector, show.lines = F)

# Gene 1 (not declared significant by maSigPro)
Gene1 <- t_endo_data[rownames(t_endo_data) == "1", ]
PlotGroups(Gene1, edesign = final_endo_design, show.fit = T, dis = matrix_endo_design$dis, groups.vector = matrix_endo_design$groups.vector, show.lines = F)

Test if theta = 10 is a good approximation using edgeR

Compare results from maSigPro when degree = 2 and degree = 5

The goal of this section is to explore the extent to which the choice of degree number affects the results. In the above analysis, we degree = 5 because this is the total # of timepoints - 1. Now, we are going to compare degree = 5 with degree = 2 because we want to avoid potential overfitting.

# Do everything the same until you have to specify the degree #

matrix_endo_design <- make.design.matrix(final_endo_design, degree = 2)
#rownames(matrix_endo_design$edesign) <- c("G1.T1.1", "G1.T2.1", "G1.T6.1", "G1.T3.1","G1.T4.1", "G1.T5.1", "G1.T1.2", "G1.T2.2", "G1.T6.2", "G1.T5.2", "G1.T1.3", "G1.T2.3", "G1.T6.3", "G1.T3.3","G1.T4.3", "G1.T5.3","G1.T1.4", "G1.T2.4", "G1.T6.4", "G1.T3.4","G1.T4.4", "G1.T5.4", "G2.T1.1", "G2.T2.1", "G2.T6.1", "G2.T3.1","G2.T4.1", "G2.T5.1", "G2.T1.2", "G2.T2.2", "G2.T6.2", "G2.T3.2", "G2.T4.2","G2.T5.2", "G2.T1.3", "G2.T2.3", "G2.T6.3", "G2.T3.3","G2.T4.3", "G2.T5.3","G2.T1.4", "G2.T2.4", "G2.T6.4", "G2.T3.4","G2.T4.4", "G2.T5.4")

# Look at the design matrix

head(matrix_endo_design$dis)
        Group.2vsGroup.1 Time TimexGroup.2 Time2 Time2xGroup.2
G1.T1.1                0    0            0     0             0
G1.T2.1                0    0            0     0             0
G1.T6.1                0    0            0     0             0
G1.T3.1                0    0            0     0             0
G1.T4.1                0    2            0     4             0
G1.T5.1                0    2            0     4             0
head(matrix_endo_design$edesign)
        Time Replicate Group.1 Group.2
G1.T1.1    0         1       1       0
G1.T2.1    0         1       1       0
G1.T6.1    0         1       1       0
G1.T3.1    0         1       1       0
G1.T4.1    2         2       1       0
G1.T5.1    2         2       1       0
  # This generates a matrix with the headers of Group.2vsGroup.1, Time, Time*Group.2 (Group.2 = 1 iif a case), Time^2, Time^2xGroup.2, etc. 

# Look at the assignment of regression variables to experimental groups. The output matches the format of the examples in the maSigPro User's Guide. 

matrix_endo_design$groups.vector
[1] "Group.2vsGroup.1" "Group.1"          "Group.2vsGroup.1"
[4] "Group.1"          "Group.2vsGroup.1"
endo_p_vector <- p.vector(t_endo_data, matrix_endo_design, counts = TRUE, theta = 10, Q = 0.10, MT.adjust = "BH")
[1] "fitting gene 100 out of 500"
[1] "fitting gene 200 out of 500"
[1] "fitting gene 300 out of 500"
[1] "fitting gene 400 out of 500"
[1] "fitting gene 500 out of 500"
# Record unadjusted p-values 
head(endo_p_vector$p.vector)
       p.value
1 2.802581e-01
2 3.794881e-09
3 6.521141e-01
4 4.154375e-08
5 7.299643e-01
6 8.665998e-07
# save output if output has not been saved already
if (!file.exists("../data/p_value_maSigPro_df_2.txt")) {
  write.table(endo_p_vector$p.vector, 
              "../data/p_value_maSigPro_df_2.txt", sep="\t")
}


# Find the number of significant genes at FDR 10%
endo_p_vector$i
[1] 196
# Find the p-value (of the F statistic of the model) at the 10% false discovery control level

head(endo_p_vector$p.adjusted)
[1] 4.462709e-01 6.776572e-08 7.952611e-01 5.326122e-07 8.507743e-01
[6] 8.175470e-06
rownames(p_value_endo_genes_masigpro) <- c(1:500)
head(endo_p_vector$SELEC)
     G1.T1.1   G1.T2.1   G1.T6.1   G1.T3.1   G1.T4.1   G1.T5.1   G1.T1.2
2  10.426795 10.425668 10.431465 10.380684 10.400377 10.318474 10.392589
4  10.298262 10.369703 10.223213 10.277187 10.277221 10.337994 10.279661
6  10.539482 10.622814 10.471043 10.524306 10.597834 10.531749 10.546683
7  10.462789 10.343998 10.324990 10.253827 10.388411 10.376206 10.085892
8   9.988518  9.945109  9.895405  9.853457  9.971380  9.911852  9.621721
12  8.412277  8.675222  9.166179  8.765615  8.565031  8.686261  8.712595
     G1.T2.2   G1.T6.2   G1.T5.2   G1.T1.3   G1.T2.3   G1.T6.3   G1.T3.3
2  10.468801 10.436231 10.388380 10.426825 10.316722 10.377514 10.520698
4  10.443396 10.389979 10.289532 10.342484 10.391822 10.353607 10.331073
6  10.532176 10.554666 10.494464 10.510668 10.506683 10.508268 10.554171
7  10.295800 10.414093 10.333255 10.187576 10.386130 10.347243 10.141086
8   9.555560 10.018199  9.648402  9.829410  9.975994  9.479375  9.781885
12  9.051227  8.561975  9.026538  8.972083  8.241176  8.850374  8.583355
     G1.T4.3   G1.T5.3   G1.T1.4   G1.T2.4   G1.T6.4   G1.T3.4   G1.T4.4
2  10.389826 10.331431 10.374772 10.443076 10.413493 10.242528 10.453572
4  10.437346 10.236776 10.227200 10.468659 10.249945 10.173324 10.231207
6  10.554849 10.547970 10.537389 10.506901 10.521399 10.492773 10.495377
7  10.355868 10.491885 10.324859 10.332409 10.389734 10.302499 10.290619
8  10.007532  9.942516  9.832475  9.769327 10.012252  9.879758  9.848345
12  8.173293  7.968666  9.089302  8.987322  8.377931  8.240121  8.891787
     G1.T5.4   G2.T1.1   G2.T2.1   G2.T6.1   G2.T3.1   G2.T4.1   G2.T5.1
2  10.438108 10.453630 10.561966 10.461388 10.524897 10.540805 10.663101
4  10.319068 10.124108 10.221323 10.308086 10.175954 10.362430 10.250829
6  10.543946 10.524978 10.599979 10.625198 10.559037 10.551847 10.613271
7  10.235055 10.412051 10.414153 10.347725 10.277462 10.583043 10.526909
8   9.952325  9.640693  9.760887  9.778888  9.642967 10.107978  9.426661
12  8.510571  8.905580  8.506334  7.983440  7.445418  8.739536  8.534050
     G2.T1.2   G2.T2.2   G2.T6.2   G2.T3.2   G2.T4.2   G2.T5.2   G2.T1.3
2  10.588628 10.576126 10.596085 10.426024 10.526802 10.525729 10.592501
4  10.305848 10.323513 10.642014 10.608341 10.549307 10.621620 10.587241
6  10.632894 10.590642 10.598807 10.538555 10.646282 10.608020 10.597409
7  10.405050 10.590742 10.460729 10.553675 10.409944 10.470646 10.405081
8   9.524494  9.607370  9.099185  9.236593  9.607034  9.493788  9.463276
12  8.042056  8.073403  8.512984  7.397562  8.337349  8.058327  8.274102
     G2.T2.3   G2.T6.3   G2.T3.3   G2.T4.3   G2.T5.3   G2.T1.4   G2.T2.4
2  10.583271 10.514014 10.381738 10.571650 10.502159 10.524897 10.524360
4  10.650578 10.541148 10.647257 10.574133 10.561655 10.175954 10.503066
6  10.581927 10.623325 10.577121 10.652282 10.583043 10.559037 10.558102
7  10.491274 10.394090 10.387795 10.456827 10.445318 10.277462 10.486234
8   9.478228  9.639457  9.644652  9.618070  9.798738  9.642967  9.521055
12  8.220672  7.769801  6.318968  8.473659  7.483807  7.445418  6.722630
     G2.T6.4   G2.T3.4   G2.T4.4   G2.T5.4
2  10.494131 10.470391 10.492079 10.451725
4  10.291162 10.323743 10.322560 10.274327
6  10.590893 10.595234 10.582967 10.590793
7  10.422847 10.480775 10.444328 10.334425
8   9.849137  9.944965  9.790935  9.924662
12  8.607582  8.875287  8.495970  8.160232
# Execute the stepwise (forward) regression. At each regression step, the p-value of each variable is computed and variables get in/out when the p-value is lower/higher than the given cutoff (alfa). 

endo_t_stat <- T.fit(endo_p_vector)
[1] "fitting gene 100 out of 196"
[1] "Influence: 6 genes with influential data at slot influ.info. Model validation for these genes is recommended"
# p-value of the regression ANOVA, R-squared of the model, and p-value of the regression coefficients of the selected variables

head(endo_t_stat$sol)
        p-value R-squared p.valor_beta0 p.valor_Group.2vsGroup.1
2  1.527375e-11 0.5081206 2.456990e-109             2.703534e-08
4  7.850667e-09 0.4634433  1.214060e-98                       NA
6  1.909168e-09 0.4505929 2.384086e-121             3.314073e-07
7  1.174454e-05 0.3034469 4.506999e-102             7.185112e-05
8  2.409309e-06 0.3750073  1.086706e-85             1.253418e-05
12 7.271254e-07 0.3899586  2.733230e-65                       NA
   p.valor_Time p.valor_TimexGroup.2 p.valor_Time2 p.valor_Time2xGroup.2
2            NA                   NA            NA                    NA
4            NA         2.776041e-07            NA          3.756369e-07
6            NA                   NA            NA                    NA
7            NA                   NA            NA                    NA
8            NA                   NA            NA          4.695328e-03
12           NA         3.610675e-06            NA          6.845323e-06
# Obtaining lists of significant genes for each experimental group. We can set and R-squared value so that the models must be greater than 0.2.

endo_sig_genes <- get.siggenes(endo_t_stat, rsq = 0.2, var = "groups")

# Get the lists of significant genes

  # The first list (Group.1) contains genes whose expression is significantly different from a 0 profile in the reference group. 
  # The second list (Group.2vsGroup.1) contains differentially expressed curves.  We are most interested in the second list because it contains genes whose profiles for the experimental group is different from the reference group. 

names(endo_sig_genes$sig.genes)
[1] "Group.1"          "Group.2vsGroup.1"
endo_sig_genes$summary
    Group.1 Group.2vsGroup.1
1        26                2
2        33                4
3        36                6
4        51                7
5        52                8
6        63               12
7       120               19
8       139               21
9       142               22
10      176               23
11      188               26
12      189               30
13      191               33
14      202               36
15      205               37
16      219               39
17      245               41
18      250               44
19      256               45
20      262               50
21      272               51
22      279               52
23      336               56
24      358               58
25      363               59
26      365               62
27      366               63
28      392               64
29      394               68
30      395               73
31      396               74
32      410               76
33      447               82
34      462               84
35      468               87
36      469               89
37      473               96
38      500              103
39                       107
40                       108
41                       113
42                       116
43                       117
44                       119
45                       120
46                       123
47                       130
48                       133
49                       134
50                       139
51                       141
52                       142
53                       144
54                       154
55                       157
56                       158
57                       161
58                       165
59                       168
60                       170
61                       174
62                       176
63                       178
64                       182
65                       183
66                       184
67                       185
68                       187
69                       189
70                       190
71                       191
72                       196
73                       200
74                       202
75                       205
76                       207
77                       208
78                       211
79                       216
80                       219
81                       222
82                       223
83                       224
84                       226
85                       229
86                       233
87                       234
88                       236
89                       245
90                       248
91                       250
92                       251
93                       253
94                       256
95                       257
96                       261
97                       262
98                       269
99                       270
100                      272
101                      274
102                      277
103                      279
104                      280
105                      282
106                      285
107                      288
108                      289
109                      295
110                      306
111                      308
112                      310
113                      311
114                      315
115                      317
116                      320
117                      325
118                      326
119                      331
120                      332
121                      335
122                      336
123                      339
124                      343
125                      348
126                      353
127                      354
128                      355
129                      358
130                      363
131                      364
132                      365
133                      366
134                      372
135                      375
136                      380
137                      381
138                      382
139                      384
140                      387
141                      388
142                      391
143                      392
144                      394
145                      395
146                      396
147                      401
148                      403
149                      409
150                      410
151                      411
152                      413
153                      416
154                      420
155                      422
156                      425
157                      426
158                      430
159                      431
160                      437
161                      439
162                      444
163                      445
164                      446
165                      447
166                      450
167                      451
168                      453
169                      456
170                      457
171                      460
172                      462
173                      463
174                      465
175                      466
176                      468
177                      469
178                      473
179                      474
180                      475
181                      478
182                      479
183                      482
184                      484
185                      486
186                      489
187                      492
188                      499
189                      500
head(endo_sig_genes$sig.genes$Group.2vsGroup.1)
$sig.profiles
      G1.T1.1   G1.T2.1   G1.T6.1   G1.T3.1   G1.T4.1   G1.T5.1   G1.T1.2
2   10.426795 10.425668 10.431465 10.380684 10.400377 10.318474 10.392589
4   10.298262 10.369703 10.223213 10.277187 10.277221 10.337994 10.279661
6   10.539482 10.622814 10.471043 10.524306 10.597834 10.531749 10.546683
7   10.462789 10.343998 10.324990 10.253827 10.388411 10.376206 10.085892
8    9.988518  9.945109  9.895405  9.853457  9.971380  9.911852  9.621721
12   8.412277  8.675222  9.166179  8.765615  8.565031  8.686261  8.712595
19   8.291296  7.982416  7.588324  8.093768  8.568266  8.379309  7.473637
21  10.374616 10.453082 10.524628 10.476104 10.342258 10.456079 10.484417
22   9.974598  9.953943  9.888831  9.746307  9.924515  9.930227  9.778264
23  10.412171 10.481645 10.398397 10.268339 10.374272 10.391362 10.424214
26   9.731690  9.760714  9.583007  9.837508  9.721066  9.684398  9.724480
30  10.386592 10.278803 10.626533 10.630287 10.345799 10.414123 10.499160
33  10.632822 10.600751 10.577987 10.572624 10.571009 10.577223 10.516915
36  10.642373 10.678514  9.410420  8.600983 10.635495 10.680263  8.945724
37   9.319643  9.328657  9.448570  9.502338  9.472166  9.469469  9.533076
39   9.175128  9.279960  9.503010  9.420277  9.120634  9.211340  9.665103
41   8.588397  8.373323  8.726157  8.894944  8.671972  8.645586  8.743532
44   9.589325  9.599405  9.825039  9.777981  9.691964  9.728181  9.823362
45  10.043771  9.975110  9.778718  9.868741  9.995246  9.878067  9.949273
50  10.324104 10.418196 10.500069 10.211413 10.370925 10.246119 10.493910
51  10.269102 10.242813 10.455877 10.125551 10.365144 10.392865 10.401471
52  10.113789 10.145217  9.956222  9.995337 10.129347 10.011759 10.009333
56   9.108751  9.100079  9.369052  9.657715  9.017968  9.258750  9.147507
58  10.085642 10.191482 10.308319 10.308553 10.135710  9.937599 10.385451
59   9.475240  9.481207 10.009917  9.806591  9.483645  9.528285  9.879605
62   9.095154  8.807621  9.013839  8.839277  9.045937  8.849084  8.874588
63  10.031749 10.051864 10.126031 10.129308 10.136225 10.067008 10.080168
64  10.115651 10.060320 10.289838 10.161689 10.230126 10.226404 10.276223
68  10.500729 10.340128 10.365428 10.234768 10.411569 10.341484 10.317086
73   7.428333  7.027315  8.782476  7.963460  7.374002  7.446585  8.367765
74  10.529640 10.285991 10.551480 10.570470 10.455705 10.475004 10.407289
76  10.009018 10.190244  9.628063  9.805323 10.064926 10.057024  9.818311
82  10.061815 10.232539 10.270558 10.015431 10.111639 10.217897 10.293907
84  10.633569 10.560230 10.607698  5.808142 10.630263 10.674406 10.584309
87   9.345745  9.528285  9.307376  8.639234  9.190648  9.493638  9.037296
89  10.638089 10.621547 10.661439 10.616658 10.679688 10.651407 10.605396
96  10.246616 10.207141 10.505971 10.453890 10.167773 10.120009 10.374491
103 10.373054 10.475935 10.279077 10.132613 10.393416 10.415023 10.329703
107 10.085309 10.264618  9.988656  9.879912 10.128509 10.172713 10.079330
108  9.666499  9.513256  9.974831  9.818311  9.901636  9.811537  9.938758
113 10.489105 10.541571 10.491108 10.501774 10.519943 10.545289 10.526293
116  9.915959  9.785773  9.678968  9.556480  9.690727 10.079791  9.776393
117  8.539150  9.333531  8.941022  8.332789  8.982059  8.668368  9.144094
119 10.689146 10.664947  8.987822  9.484481 10.675792 10.284353  8.998137
120  8.257386  7.784473  7.037906  5.609472  7.594381  8.067463  5.777652
123  7.745436  8.509766  8.153350  8.169620  6.180017  7.551712 10.679113
130 10.490580 10.564680 10.415622 10.351214 10.519916 10.579082 10.492995
133  9.071653  8.708309  9.671051  9.389741  9.234838  9.149422  9.258654
134  9.381517  8.916640  8.464847  9.339261  8.874448  9.093245  9.004054
139 10.444066 10.304108 10.324170 10.176487 10.327545 10.351948 10.201479
141  9.769156  9.860162  9.917883  9.866927  9.580316  9.714685  9.819617
142  8.819813  8.744807  8.946765  9.302281  9.005773  8.751316  9.185535
144 10.063308  9.951420  9.905386  9.865526  9.950276  9.999979  9.849559
154  9.976134  9.928424 10.117550 10.091791 10.115449 10.167773 10.118276
157  9.464130  9.512369  9.824174  9.839056  9.613469  9.591991  9.716194
158  6.987490  8.868835  7.156956  8.808967  5.886104  8.251925 10.628206
161 10.602691 10.486569 10.625149 10.544367 10.519457 10.570676 10.468233
165  9.456810  9.761233  9.536618  8.976009  9.660843  9.731987  9.216024
168 10.373272 10.224556 10.359551 10.435145 10.345156 10.389395 10.277943
170 10.629271 10.663008 10.552448 10.613271 10.637777 10.621498 10.545157
174 10.296306 10.427387 10.425757 10.327709 10.254813 10.457286 10.292993
176 10.226259 10.059380 10.227670 10.201553 10.024731 10.053329 10.252065
178  8.142936  8.303009  8.097122  8.115521  8.326517  8.141190  8.550241
182  9.710388  9.919853  9.349406  9.686450  9.914230  9.834245  9.293026
183  9.762327  9.565775  9.806701  9.638545  9.950848  9.506214  9.753827
184 10.576228 10.630045 10.617417 10.590114 10.562069 10.619667 10.585801
185  9.220588  9.407304  9.614338  9.913933  9.305651  9.687568  9.603530
187  9.384630  9.635543  9.647240  9.546098  9.509482  9.617071  9.561912
189  9.584934  9.685642  9.535679  9.664596  9.639587  9.583558  9.368967
190 10.051131 10.245054  9.915169 10.015565 10.036969 10.110095 10.033067
191  9.886545  9.682654  9.746073  9.683962  9.750453  9.623906  9.510963
196 10.142977  9.966791 10.424986 10.437903 10.184183 10.285479 10.274120
200  9.419709  9.030496  8.981933  9.339349  9.518046  9.181426  8.832150
202  7.882692  7.789455  7.315218  5.883322  7.614805  7.354362  7.114769
205 10.603511 10.502516 10.481617 10.515506 10.612164 10.593354 10.578624
207  9.058936  9.154933  9.381517  9.632597  8.832004  9.108640  9.212937
208  9.264165  9.465370  8.805225  9.234252  9.184202  9.139596  9.140025
211 10.533295 10.462360 10.566923 10.515099 10.421537 10.215374 10.395314
216  9.865890  9.974365 10.061858 10.028974  9.817875  9.988518  9.977621
219 10.326793 10.350862 10.308919 10.322921 10.332148 10.333743 10.386006
222 10.507175 10.622863 10.619228 10.610562 10.519241 10.527981 10.560800
223 10.568338 10.541096 10.432025 10.431554 10.484473 10.559115 10.449236
224 10.208506 10.278012 10.379846 10.325941 10.248813 10.278459 10.243489
226 10.547471 10.538343 10.592175 10.639670 10.482374 10.578853 10.457976
229  9.452816  9.431402  9.406894  9.193398  9.525005  9.611797  9.377717
233 10.051692 10.286605 10.150074  9.980911 10.318903 10.174621 10.155257
234  9.960907 10.201664 10.036312  9.862666 10.040332 10.121659  9.995930
236  9.558529  9.603058  8.812248  9.574011  9.430279  9.289521  9.039789
245  8.221748  6.886532  8.553718  8.224967  7.724005  8.560827  8.691651
248  9.802949 10.103895 10.080252  9.741439  9.844427  9.716435 10.150074
250  9.445808  9.296335  9.458294  9.410584  9.522227  9.478993  9.480138
251  7.865955  7.974877  8.361241  7.404279  7.681099  8.606302  7.356918
253 10.382048 10.377390 10.319167 10.386716 10.404960 10.348910 10.390686
256  9.850930  9.466300  9.592878  9.472551  9.770756  9.614271  9.328568
257 10.374678 10.383596 10.296036 10.255798 10.352236 10.320486 10.311150
261 10.480634 10.241601 10.487406 10.399159 10.412171 10.483690 10.439396
262  9.028699  8.669914  8.871084  9.152817  8.928375  8.634265  8.734238
269 10.486485 10.569084 10.526105 10.542522 10.495239 10.480213 10.522719
270  9.812797  9.574497  9.988518  9.816349  9.885171  9.805323 10.009108
272 10.208653 10.212001 10.069553 10.218043 10.243205 10.187312 10.046418
274  9.548882  9.144521  9.611530  9.536690  9.516722  9.036106  9.250138
277 10.561603 10.420643 10.628932 10.633160 10.554301 10.496124 10.619838
279 10.391669 10.351118 10.320980 10.274810 10.364545 10.407651 10.371395
280  9.740204  9.824228  9.950657  9.585140  9.845329  9.821952  9.892427
282  9.590761  9.662371  9.429717  9.356171  9.500020  9.597913  9.565073
285 10.217897 10.133329 10.244627 10.310818 10.140179 10.236669 10.299340
288 10.503395 10.498057 10.557816 10.497422 10.483634 10.422847 10.496317
289 10.155840 10.310618  9.901235 10.110705 10.157354 10.163734 10.141126
295  8.856946  8.402231  9.421735  9.120963  8.460411  8.182559  9.021115
306  9.555489  9.619731  9.972920  9.926862  9.746015  9.542015  9.820649
308 10.094604  9.616139 10.212882 10.025440 10.040419  9.781320 10.188328
310  9.400713  9.152817  9.699718  9.737433  9.463586  9.623311  9.445966
311 10.149253 10.074200  9.930762  9.899981 10.110461 10.188065  9.970913
315 10.186031 10.306416 10.239174 10.370424 10.137096 10.152065 10.215740
317 10.385728 10.269172 10.441529 10.455820 10.397543 10.403020 10.417359
320 10.540276 10.583676 10.658224  7.760467 10.552160 10.620400 10.671487
325  9.116579  9.765145  9.053570  8.874868  9.541872  9.304650  9.098850
326 10.524387 10.461244 10.477485 10.430846 10.461617 10.399189 10.377857
331 10.432291 10.483354 10.441705 10.492773 10.439308 10.430374 10.488938
332 10.139784 10.226549 10.141677 10.143685  9.901686  9.985390 10.008028
335 10.073315 10.235880 10.149527 10.319728 10.314305 10.102051 10.240745
336  8.543446  9.073030  8.531293  9.222269  9.052048  8.945984  8.671972
339 10.263327 10.217933 10.387671 10.360279 10.218408 10.227128 10.172713
343 10.137611 10.173973 10.091501  9.813070 10.198356 10.111193 10.144039
348  8.456806  7.888710  8.710290  8.916506  8.539346  8.772920  8.764522
353  9.659057  9.583007  9.791270  9.947648  9.774972  9.672816  9.935228
354  9.787291  9.886901  9.773322  9.684025  9.852300  9.989757  9.787964
355 10.406563 10.366026  9.616805  8.880864 10.385852 10.463475  8.987322
358 10.323644 10.344095 10.308986 10.124108 10.381614 10.334750 10.282335
363  9.700453  9.572271  9.808627  9.791382  9.794175  9.733766 10.015163
364  8.935245  9.069583  9.324383  8.615227  9.025576  9.175128  9.000113
365  9.041922  9.168789  9.052516  8.865735  9.095603  9.093132  9.352447
366  7.602900  4.595120  7.865572  5.342334  8.409608  7.800163  8.028455
372 10.168924 10.286127 10.318111 10.331105 10.173629 10.162809 10.311350
375  9.460866  9.470626  9.855557  9.716495  9.455950  9.569203  9.571296
380 10.359044 10.304409 10.379939 10.324432 10.310085 10.351182 10.357648
381 10.137175 10.336179 10.211891 10.370675 10.284967 10.144157 10.211597
382 10.128589 10.197686 10.158246 10.085476 10.216252 10.110461 10.228863
384  8.357494  8.987072  8.759512  8.241967  8.978787  9.176266  8.810907
387 10.199658 10.251571 10.486569 10.475117 10.256852 10.296441 10.399677
388  8.736650  8.208764  8.669227  8.606485  8.058011  8.157084  8.458716
391  9.855977  9.667005 10.039198  9.782506  9.649627  9.806316  9.836974
392 10.491635 10.467892 10.308119 10.402868 10.518133 10.475342 10.442230
394  9.084664  9.101195  9.148252  9.170351  9.304104  9.205730  9.277158
395 10.444765 10.223504 10.497284 10.541730 10.315266 10.315332 10.525944
396 10.351214 10.574031 10.525354 10.493328 10.576330 10.492579 10.540911
401 10.117833  9.889186 10.311848 10.324695 10.114842  9.978038 10.209906
403  7.857868 10.687617  8.597482  8.049746  7.056175  7.876638  7.708860
409  9.028219  8.168486  8.024535  8.581669  9.574150  8.269501  8.523374
410  9.927399 10.098190  9.990674 10.124389  9.999525 10.040550 10.200662
411  9.417192  9.105979  9.217018  8.992309  9.219003  9.221181  9.161150
413  7.808323  8.052933  8.489205  8.439448 10.677708  6.052089  7.266827
416 10.554275  8.783396 10.589736 10.536646 10.636000  6.746412 10.590994
420 10.159098 10.126711 10.315167 10.240924 10.297521 10.245729 10.383101
422  9.524494  9.777641  9.617803  9.762903  9.634169  9.653743  9.760367
425  7.827640  5.993961  8.545781 10.645092  8.204125  8.097122  6.680855
426  8.615771  7.685244  8.217439  8.466742  8.208764  7.638198  8.410053
430  9.027259  9.159889  9.446755  9.612467  9.425774  9.261604  9.429235
431 10.350414 10.373866 10.358441 10.406019 10.357489 10.372960 10.472856
437 10.443046 10.523177 10.549936 10.556698 10.446916 10.438723 10.478780
439 10.402443 10.361608 10.376954 10.454841 10.385759 10.397940 10.376705
444  8.538367 10.584334  6.947937 10.663756  8.819370  8.818630  8.455743
445 10.198021 10.324137 10.535132 10.348654 10.250511 10.200216 10.424273
446 10.304744 10.218554 10.468602 10.358822 10.280965 10.349263 10.450597
447 10.690034 10.647304  8.522976  7.625107  6.434547  7.904335  4.499810
450  9.826876  9.725736  9.760425  9.414586  9.789647  9.727466  9.719625
451  9.992002  9.971940 10.367882 10.130264 10.007848 10.059080 10.132732
453  9.784028  9.518266  9.546955  9.849454  9.679281  9.750103  9.626086
456  9.950419  9.721126  9.684709  9.690789  9.802893  9.895052  9.680844
457 10.364261 10.385204 10.477344 10.454466 10.402989 10.404929 10.402382
460 10.450973 10.310252 10.589912 10.659516 10.428039 10.525380 10.508241
462 10.627285 10.592903  8.009031  8.035279 10.688028  7.689371  6.054439
463  8.715552  8.130942  9.637306  8.737773  8.307706  8.491055  9.456341
465 10.559815 10.605743 10.520833 10.620864 10.540646 10.647114 10.578471
466 10.054834 10.093984 10.144589 10.070188 10.069637 10.068578 10.143646
468  9.924955  9.750511  9.629774  9.821844  9.815421  9.671366  9.697508
469 10.689988  6.978214 10.662610 10.688598  6.361302  7.372746  7.355641
473  6.886532  7.139660  6.888572  7.287561  5.159055  4.663439  6.887553
474  9.594037  9.820812  9.405578  9.261889  9.649756  9.610592  9.464207
475 10.118438 10.267714 10.215960 10.025263 10.109322 10.187350 10.024155
478  9.940061 10.248884  9.672942  9.597370 10.096790  9.736724  9.665611
479 10.111071 10.058524  9.966368 10.011624 10.131021 10.113303  9.979012
482  9.078864  9.277158  9.239414  9.291644  8.766394  9.134539  8.776784
484 10.606214 10.483102 10.647898 10.487740 10.462875 10.535105 10.505314
486 10.237421 10.533748 10.333710 10.517213 10.299811 10.399920 10.339385
489  9.622053  9.583145  8.981053  9.488199  9.562405  9.351666  9.307286
492  9.532641  8.992309  9.767324  9.811482  9.354960  9.405907  9.701861
499 10.324695 10.141441 10.149371 10.284728 10.297723 10.254532 10.127990
500  6.180017  4.859812  7.386471 10.679895  4.430817 10.680976  8.032685
      G1.T2.2   G1.T6.2   G1.T5.2   G1.T1.3   G1.T2.3   G1.T6.3   G1.T3.3
2   10.468801 10.436231 10.388380 10.426825 10.316722 10.377514 10.520698
4   10.443396 10.389979 10.289532 10.342484 10.391822 10.353607 10.331073
6   10.532176 10.554666 10.494464 10.510668 10.506683 10.508268 10.554171
7   10.295800 10.414093 10.333255 10.187576 10.386130 10.347243 10.141086
8    9.555560 10.018199  9.648402  9.829410  9.975994  9.479375  9.781885
12   9.051227  8.561975  9.026538  8.972083  8.241176  8.850374  8.583355
19   7.370231  8.304742  7.608871  7.491088  8.603371  7.917536  8.474912
21  10.518295 10.474213 10.424184 10.505396 10.420405 10.498333 10.410727
22  10.028798  9.920640  9.851457  9.875242  9.992597  9.921180  9.976692
23  10.445405 10.394090 10.412441 10.415502 10.416730 10.381273 10.428630
26   9.793003  9.633514  9.712690  9.730681  9.587886  9.584108  9.697447
30  10.534999 10.430226 10.634893 10.568852 10.402564 10.584132 10.591421
33  10.579768 10.613590 10.540488 10.518997 10.561551 10.632460 10.595334
36   9.248503  6.794587  8.755422  9.010913 10.663966  9.046880  9.093919
37   9.670357  9.524567  9.473089  9.384798  9.427466  9.409273  9.445808
39   9.236495  9.532859  9.405496  9.397401  9.283405  9.315061  9.279400
41   8.271548  8.910046  8.899185  8.981304  8.182559  8.463792  8.487764
44   9.833655  9.590966  9.686264  9.837615  9.614204  9.392745  9.764743
45  10.033770 10.035962  9.919115  9.881600  9.920640  9.904787  9.897872
50  10.574159 10.491274 10.515289 10.502352 10.239067 10.557192 10.272220
51  10.400316 10.270939 10.421686 10.396658 10.359582 10.483998 10.214202
52  10.049793 10.103362  9.885425  9.935180 10.034604 10.026324 10.006946
56   9.253879  9.098179  9.404920  9.594718  8.908018  8.852093  9.332823
58  10.496372 10.176982 10.462389 10.414003 10.210016 10.180740 10.176183
59   9.780755  9.685456 10.065904  9.978456  9.699166  9.961521  9.796904
62   8.786457  8.942984  8.789203  8.861067  8.888067  9.094930  8.951051
63  10.154130 10.080168 10.141126 10.068748  9.942708  9.996887 10.103608
64  10.297858 10.141401 10.286809 10.172827 10.135155 10.309319  9.974784
68  10.311450 10.502379 10.203555 10.197835 10.461416 10.279249 10.444707
73   8.771835  7.573017  8.528133  8.674368  7.259116  8.351139  9.426580
74  10.418644 10.453890 10.526024 10.552030 10.492801 10.434557 10.511213
76   9.887511 10.237922  9.752258  9.771612 10.007893  9.890453  9.941602
82  10.024687 10.116338 10.302129 10.121377 10.331268 10.289736  9.855767
84  10.670234 10.642373 10.646924 10.652046 10.673850 10.652093 10.619448
87   8.939450  9.331495  9.076123  9.214930  9.129239  9.055089  8.691315
89  10.563672 10.660173 10.600228 10.611252 10.600751 10.590893 10.605124
96  10.534866 10.239424 10.421597 10.459583 10.347757 10.437317  9.987691
103 10.274189 10.399007 10.340225 10.232288 10.341581 10.256185 10.218590
107 10.173477 10.077525 10.026943 10.040725 10.143921 10.017753 10.071583
108  9.756321  9.909122 10.143881  9.979939 10.044249  9.598524  9.792779
113 10.629513 10.510450 10.484138 10.545920 10.531056 10.574772 10.468034
116  9.572550  9.894800  9.728717  9.695725  9.844693  9.978224  9.753885
117  9.154405  9.073489  8.867287  8.920790  8.554104  9.101752  8.323608
119  9.218507 10.662048  9.189525  9.323401 10.592878  7.010312  9.074864
120  8.244071  8.294799  5.697093  7.539027  8.443547  8.084562  8.505121
123  7.878534  8.000685  6.751101  7.679714  7.587311  7.600402  7.274480
130 10.569443 10.498057 10.460127 10.573724 10.532150 10.547313 10.628908
133  9.411647  9.172015  9.344871  9.328479  9.144521  9.589119  9.226312
134  9.019664  9.165552  8.961366  8.842171  9.172742  8.811801  9.165029
139 10.450105 10.403717 10.284079 10.330877 10.401775 10.434322 10.419211
141  9.875602  9.708992  9.961756  9.643161  9.717158  9.885324  9.976227
142  9.296335  8.840435  9.072112  9.219399  8.919052  8.916908  8.942069
144  9.825526  9.896715 10.027429  9.906533 10.114032  9.826768  9.920148
154  9.991361  9.969275 10.139350 10.072851  9.961615 10.094562 10.149879
157  9.722745  9.461177  9.716254  9.867549  9.608647  9.846706  9.578034
158  8.550241  7.949091 10.685630  8.896862  6.895683 10.609205  8.953769
161 10.586256 10.531536 10.492329 10.557140 10.525031 10.561707 10.612090
165  9.663198  9.670925  9.465293  9.665674  9.703572  9.605216  9.406976
168 10.360216 10.350127 10.379411 10.442434 10.293060 10.344095 10.329409
170 10.532976 10.626169 10.553153 10.590038 10.602269 10.468062 10.550800
174 10.453255 10.387394 10.276085 10.337929 10.341452 10.321639 10.319134
176 10.261057 10.027164 10.320519 10.237385 10.060491 10.283772 10.131937
178  8.518193  8.512583  8.647871  8.331345  8.379309  8.456594  8.401782
182  9.405249 10.173209  9.691593  9.568155 10.355295  9.256460  9.752607
183  9.776790  9.808957  9.813180  9.804551  9.852615  9.331495  9.711782
184 10.562794 10.623033 10.565995 10.552944 10.531323 10.601274 10.586786
185  9.455324  9.595807  9.652973  9.695233  9.630760  9.395907  9.387231
187  9.380336  9.589256  9.520982  9.626086  9.498522  9.621191  9.440102
189  9.771612  9.771384  9.551658  9.401952  9.443197  9.481131  9.575331
190 10.006405  9.988472  9.995611  9.996021 10.016682  9.825580 10.014000
191  9.708081  9.718663  9.879400  8.993427  9.834137  9.823307  9.681344
196 10.283908 10.196008 10.376424 10.433498 10.174735 10.387240 10.257449
200  9.199381  9.546027  8.730044  9.095715  9.482122  8.842604  9.173780
202  8.130059  5.262690  6.461468  8.182839  7.291656  7.427739  7.721792
205 10.589862 10.582840 10.607921 10.552683 10.581597 10.588174 10.523768
207  9.613002  9.056256  9.238831  9.426097  9.269646  9.471242  9.190750
208  9.167955  9.266248  9.081711  8.988821  9.219895  9.085004  9.234350
211 10.541703 10.433645 10.370173 10.468261 10.475032 10.425757 10.568672
216 10.090714  9.978688 10.001929 10.037887  9.991544 10.039940 10.077861
219 10.314239 10.310119 10.418614 10.388565 10.277256 10.370831 10.281513
222 10.590466 10.555995 10.545236 10.618103 10.448483 10.487099 10.579870
223 10.480747 10.493300 10.455532 10.467664 10.502956 10.448512 10.432674
224 10.024776 10.290789 10.290415 10.289906 10.219465 10.342323 10.269172
226 10.347885 10.616584 10.554379 10.558076 10.532203 10.390717 10.461874
229  9.379661  9.584315  9.315241  9.326433  9.571087  9.298076  9.324562
233 10.316127 10.249486 10.066286 10.221978  9.965899 10.241922  9.912001
234  9.942420 10.041857 10.021271 10.010367 10.115732 10.009108  9.848715
236  9.383705  9.652202  9.091895  9.339964  9.564793  8.529517  9.308737
245  8.332549  8.321665  8.693329  8.314587  8.399985  8.771835  8.637107
248 10.126191  9.853194  9.977249 10.016682  9.728598 10.165352  9.932706
250  9.441135  9.415971  9.445492  9.497097  9.506511  9.479986  9.448333
251  8.686598  8.271804  5.438079  8.471359  7.788626  8.318498  8.583730
253 10.412832 10.373272 10.344577 10.333710 10.366120 10.383101 10.397909
256  9.499871  9.567175  9.539572  9.346094  9.554285  9.381769  9.214233
257 10.308586 10.353894 10.347564 10.306717 10.329866 10.327709 10.434968
261 10.251182 10.441646 10.438694 10.440186 10.451985 10.478752 10.469398
262  9.008102  8.964568  9.147507  9.048997  8.836374  8.869258  8.896725
269 10.569777 10.533535 10.510178 10.531162 10.487573 10.407289 10.516752
270 10.004915  9.620129 10.177210 10.026678  9.862874 10.077357  9.925787
272 10.109688 10.318672  9.990720 10.082303 10.277221 10.085851  9.712085
274  9.744433  9.358243  9.488956  9.667892  9.583971  9.576025  9.568784
277 10.599755 10.578293 10.682216 10.650010 10.601174 10.596260 10.589333
279 10.351661 10.379598 10.361861 10.367819 10.403384 10.439220 10.356345
280  9.765546  9.830809  9.717278  9.903137  9.795847  9.813946  9.800846
282  9.317310  9.581973  9.484709  9.369905  9.585621  9.113829  9.386225
285 10.268964 10.183805 10.289226 10.198207 10.212956 10.334880 10.280759
288 10.449873 10.477457 10.536433 10.518673 10.510069 10.465272 10.541782
289 10.017307 10.126511 10.034428 10.023091 10.116257  9.960246 10.102338
295  9.205026  8.942722  8.806724  9.150378  8.686767  9.198673  8.784315
306  9.968339  9.747418  9.937309  9.916552  9.495068  9.946547  9.793282
308  9.981420 10.166121 10.167120 10.121860 10.077399  9.990032 10.108426
310  9.322597  9.571714  9.482350  9.421492  9.459308  9.726273  9.362718
311  9.991773 10.126831 10.049059 10.018467 10.148784  9.953277 10.088971
315 10.213946 10.228646 10.226187 10.181952 10.225172 10.243738 10.240138
317 10.273602 10.368510 10.385605 10.421239 10.470816 10.388226 10.378074
320 10.679297 10.395803  7.342779  7.707512 10.491413 10.571625 10.649630
325  9.449436  9.459931  8.869961  9.048527  9.251674  9.265018  9.129672
326 10.537601 10.419241 10.429310 10.422222 10.435292 10.475596 10.544157
331 10.550800 10.448831 10.457373 10.472148 10.393508 10.496068 10.547103
332 10.109526 10.186333 10.030737 10.125911  9.978038 10.034472 10.064075
335 10.014000 10.144078 10.240103 10.274948 10.089303  9.948652 10.226295
336  8.710125  8.995537  8.917981  8.685585  9.101975  8.609043  8.702178
339 10.043423 10.286400 10.295732 10.364608 10.255868 10.011759 10.333613
343 10.034954 10.165813 10.014447 10.070569 10.105653  9.986633 10.169576
348  7.967973  7.754910  8.689969  8.807472  8.295798  8.922925  8.860783
353 10.013418  9.611664  9.984699  9.968807  9.678655  9.676336 10.010457
354  9.973899  9.887866  9.950753  9.983269  9.874213  9.852826  9.587612
355  9.275191 10.528061  8.789051  9.333619 10.465842  9.363748  8.765459
358 10.301088 10.373960 10.312779 10.287797 10.350702 10.386037 10.346281
363  9.817930  9.708324  9.717820  9.887815  9.812030  9.860528 10.266532
364  8.879612  9.300638  9.167746  8.892886  8.923458  8.761393  8.215547
365  8.787983  9.275472  9.369223  8.950014  8.952347  9.142597  9.008102
366  7.003065  7.303170  7.120444  7.602401 10.676231  8.584104  7.532624
372 10.221832 10.237600 10.333353 10.290653 10.202480 10.239067 10.209869
375  9.790543  9.688622  9.571993  9.755162  9.438989  9.748470  9.930714
380 10.228249 10.303203 10.364419 10.328592 10.325252 10.305279 10.371771
381 10.453630 10.028445 10.241387 10.382048  9.976924 10.211671 10.167351
382 10.240495 10.247219 10.143213 10.161264 10.104467 10.248530 10.092578
384  8.756053  8.752898  8.833900  8.700681  8.860783  8.649974  8.859931
387 10.526588 10.278803 10.434557 10.532496 10.352523 10.344642 10.423798
388  8.674539  8.445053  8.646993  8.821437  8.939581  8.778634  8.541105
391 10.046158  9.727168  9.731215  9.877708  9.757247 10.018868  9.801178
392 10.405081 10.380591 10.477682 10.357584 10.465899 10.480101 10.351533
394  9.175956  9.166179  9.289244  9.195937  9.147507  9.022805  9.146548
395 10.529987 10.438752 10.553466 10.473478 10.389703 10.498167 10.522396
396 10.593204 10.489384 10.501939 10.555240 10.399281 10.548678 10.434145
401 10.320057 10.060235 10.313376 10.310518 10.045942 10.212332 10.262525
403 10.641082  5.673323  8.053251  7.946618  7.425358 10.685904  6.511745
409  8.390268  9.200088  6.931472  8.822175  9.412219  8.058960 10.644281
410  9.980911 10.193878  9.900182  9.928229  9.856972  9.928180 10.184221
411  9.019180  9.243582  9.190852  9.138844  9.316501  9.006999  9.339964
413  8.183397  8.061487  8.022569  7.834392  7.717796  5.605802  6.295266
416 10.468915 10.660876 10.543919 10.471553 10.647756 10.599855 10.452302
420 10.230414 10.152611 10.312048 10.368604 10.205257 10.365805 10.112613
422  9.602855  9.573941  9.596079  9.719384  9.530320  9.200189  9.657459
425  8.122965  7.043160  7.788212  8.017308  8.114624  8.152198  6.840547
426  8.764990  8.715388  8.576028  8.757312  8.211483  9.120197  8.860073
430  9.483873  9.303284  9.298992  9.434204  9.037296  9.382191  9.374243
431 10.442901 10.357679 10.398854 10.391822 10.444241 10.438606 10.465272
437 10.552082 10.518295 10.564163 10.541994 10.445318 10.456654 10.468119
439 10.410516 10.451407 10.419748 10.386099 10.461101 10.352523 10.337054
444  7.035269  8.439664  8.389814  7.128496  8.629092  9.018211  8.188411
445 10.534360 10.270731 10.477795 10.467067 10.241173 10.521696 10.361672
446 10.441792 10.337086 10.410697 10.479511 10.380777 10.417777 10.441851
447  8.360539  6.597146  6.590301  8.226573 10.683477  8.111028  7.918265
450  9.600286  9.791214  9.508295  9.663198  9.761982  9.753536  9.783239
451 10.195709 10.078659 10.253405 10.197798 10.135749 10.334978 10.232971
453  9.709357  9.661161  9.662498  9.617404  9.705646  9.669409  9.644004
456  9.666118  9.740380  9.791158  9.702778  9.842729  9.730859  9.873389
457 10.479960 10.396017 10.330453 10.455992 10.435850 10.532203 10.518214
460 10.485452 10.521372 10.602890 10.615677 10.515425 10.540488 10.571317
462 10.538529 10.601448  7.964503  6.913737 10.644353 10.683088  5.820083
463  9.655539  8.959055  9.197863  9.200593  8.944159  9.622913  9.180500
465 10.663124 10.631060 10.583448 10.627140 10.589232 10.574133 10.498277
466 10.030032 10.028092 10.130782 10.106388 10.041378 10.099260 10.136977
468  9.623046  9.851773  9.840920  9.677528  9.840761  9.530828  9.976180
469  7.974533  7.567346 10.666301  6.579251 10.681711  7.232733 10.627818
473  6.993933  7.486053  8.176392  7.154615 10.658412  5.062595 10.507776
474  9.323490  9.620395  9.447387  9.476467  9.639457  9.268515  9.523909
475 10.218006 10.274672 10.300114 10.204481 10.370236 10.056809 10.101887
478  9.731453 10.121015  9.541441  9.527557 10.190732  9.740086  9.772695
479 10.015342 10.052037  9.978456  9.977249 10.130225 10.032057 10.057967
482  9.158099  9.000236  9.369393  9.335474  9.049467  8.834191  8.190354
484 10.568107 10.578318 10.470646 10.520401 10.560800 10.591170 10.494104
486 10.527820 10.299104 10.398489 10.545394 10.277668 10.357012 10.586130
489  9.421816  9.587475  9.381432  9.261033  9.545455  9.037771  9.564512
492  9.722146  9.194821  9.871119  9.888019  9.566195  9.948604  9.853457
499 10.024244 10.340451 10.176754 10.124308 10.467693  9.930957 10.248282
500  8.020599 10.658294  7.758333  8.429236  7.307202  7.171657  6.787845
      G1.T4.3   G1.T5.3   G1.T1.4   G1.T2.4   G1.T6.4   G1.T3.4   G1.T4.4
2   10.389826 10.331431 10.374772 10.443076 10.413493 10.242528 10.453572
4   10.437346 10.236776 10.227200 10.468659 10.249945 10.173324 10.231207
6   10.554849 10.547970 10.537389 10.506901 10.521399 10.492773 10.495377
7   10.355868 10.491885 10.324859 10.332409 10.389734 10.302499 10.290619
8   10.007532  9.942516  9.832475  9.769327 10.012252  9.879758  9.848345
12   8.173293  7.968666  9.089302  8.987322  8.377931  8.240121  8.891787
19   8.343792  8.315566  8.193953  7.646831  8.010360  8.115820  7.948738
21  10.457200 10.426202 10.397391 10.492357 10.444881 10.412081 10.451262
22   9.841506  9.823524  9.875397  9.913685  9.867238  9.837615  9.917045
23  10.392190 10.421180 10.424125 10.366183 10.445172 10.328003 10.390041
26   9.692211  9.769499  9.671429  9.709539  9.591240  9.611463  9.576857
30  10.435732 10.295192 10.544525 10.604256 10.473280 10.440858 10.533562
33  10.578547 10.494879 10.532683 10.545762 10.643685 10.555370 10.620424
36   6.946014  7.616776  8.793612  9.048527 10.645615  8.056427  9.168685
37   9.292842  9.296243  9.451638  9.480520  9.546455  9.399969  9.623641
39   9.342421  9.201300  9.392162  9.269175  9.392162  9.103423  9.490847
41   8.232440  8.424859  8.757312  8.711937  8.581857  8.808369  8.875287
44   9.627866  9.598998  9.822657  9.797349  9.562827  9.519441  9.674829
45  10.001113  9.956080 10.002428  9.860110 10.031793  9.844746  9.848873
50  10.143606 10.317285 10.633160 10.526507 10.284148 10.128469 10.452216
51  10.360976 10.310452 10.520941 10.489690 10.247786 10.260112 10.419808
52  10.068154  9.997843  9.918524  9.981790 10.033331 10.094521  9.983776
56   8.965207  8.776784  9.368625  9.132163  9.229849  8.733111  9.353401
58  10.102379 10.119727 10.357616 10.417209  9.923878 10.194738 10.347596
59   9.545955  9.571226 10.098602  9.915268  9.471704  9.485697  9.918179
62   8.911125  8.959697  8.879751  8.788746  9.038721  8.849944  8.783703
63  10.030473 10.063350 10.033682 10.007127 10.078743 10.125751 10.069299
64  10.105775 10.283669 10.269276 10.339547 10.213799 10.209353 10.317846
68  10.523419 10.428246 10.312214 10.218116 10.294110 10.392466 10.382977
73   7.532088  7.624131  8.048149  8.645410  6.562444  7.972466  8.646641
74  10.495958 10.495598 10.504876 10.441996 10.507202 10.520914 10.459009
76   9.998980  9.981744  9.732936  9.717218 10.033682  9.858176 10.046852
82  10.286877 10.152221 10.210457 10.207805 10.046852 10.016861 10.171298
84  10.642134 10.647969 10.644281 10.618641 10.650223 10.667093 10.625635
87   9.251770  9.174299  8.941284  8.994669  9.206031  9.147294  9.188504
89  10.632533 10.624785 10.614131 10.579692 10.624080 10.606833 10.652235
96  10.099712 10.245161 10.412982 10.463874 10.119405 10.174621 10.521723
103 10.383565 10.308219 10.293060 10.237636 10.351980 10.340677 10.330257
107 10.171796 10.167466 10.141165 10.042684 10.115408 10.118075 10.081425
108  9.905186  9.780755  9.790487  9.849929  9.799903  9.740969  9.914576
113 10.520347 10.582460 10.529854 10.558829 10.577783 10.515994 10.575641
116  9.832206  9.891364  9.339173  9.649949  9.932949  9.895657  9.856186
117  7.512071  8.764522  9.224736  8.968651  8.713746  7.357556  9.099632
119 10.610439 10.520051  8.586346  9.562545 10.575130 10.455849  8.570355
120  8.385261  8.649449  7.791110  8.247482  8.320448  7.848934  6.035481
123  7.877018  7.962067  7.428333  7.491645  6.206576  8.155936  7.945555
130 10.524467 10.541016 10.387641 10.557946 10.594758 10.508541 10.401501
133  8.917713  9.053920  9.455245  9.430038  9.194719  9.216919  9.460243
134  9.314520  9.303284  9.044994  8.716044  9.282382  9.227984  8.839132
139 10.352395 10.436290 10.369671 10.358917 10.356695 10.262629 10.228899
141  9.828818  9.752316 10.075927  9.714866  9.304013  9.875345  9.900232
142  8.703507  8.923458  8.969923  9.104202  8.319717  8.523374  8.805375
144  9.945972  9.922800  9.823470  9.857496  9.989161  9.946499  9.845011
154 10.051002 10.062882 10.164890 10.105653  9.979430 10.159137 10.159331
157  9.619133  9.592742  9.787066  9.848345  9.422949  9.744492  9.834834
158  7.737616  7.877397 10.653133  8.157944  8.485083  8.866158 10.676554
161 10.624031 10.556984 10.570188 10.513688 10.631423 10.573059 10.626412
165  9.488124  9.324472  9.199279  9.498297  9.886748  9.601504  9.636457
168 10.382141 10.283396 10.348750 10.319992 10.386901 10.305714 10.389365
170 10.606338 10.598907 10.559841 10.536407 10.653157 10.664106 10.548337
174 10.391515 10.452938 10.306516 10.355391 10.237349 10.390963 10.291908
176 10.107734 10.189944 10.345413 10.286741 10.120291  9.959206 10.236669
178  8.449984  8.319961  8.502486  8.531096  8.365905  8.230311  8.450412
182 10.013104  9.420277  9.342333  9.671366  9.806756  9.725974  9.246962
183  9.778264  9.699411  9.484253  9.665928  9.852300  9.383537  9.814383
184 10.581343 10.610562 10.601622 10.597334 10.486122 10.586003 10.612065
185  9.380842  9.398644  9.696094  9.510889  9.416053  9.626152  9.451560
187  9.444859  9.156095  9.443751  9.661543  9.484405  9.526610  9.656563
189  9.545526  9.399555  9.420034  9.514142  9.487745  9.564793  9.290445
190 10.130185 10.028798  9.954086  9.901285 10.012611 10.063180 10.029459
191  9.806481  9.630037  9.694062  9.467615  9.572968  9.351579  9.543306
196 10.189080 10.167735 10.332897 10.355486 10.348910 10.206698 10.404808
200  9.469546  9.086590  8.666992  8.878219  9.692520  9.484253  9.180087
202  7.085901  7.617760  7.926603  7.668561  7.670895 10.680309  6.823286
205 10.573699 10.463932 10.622546 10.554249 10.450857 10.367945 10.515696
207  9.084324  9.239705  9.446677  9.217614  8.960981  8.938663  9.287487
208  8.997395  9.556480  9.360913  8.839856  9.285355  9.265018  8.820699
211 10.478527 10.345863 10.371301 10.399433 10.331594 10.521507 10.419211
216  9.688622 10.024333 10.038499 10.012880 10.084266  9.992780  9.986219
219 10.290992 10.358631 10.426469 10.405141 10.379256 10.351565  7.268920
222 10.516590 10.498470 10.505013 10.535025 10.406352 10.585776 10.609896
223 10.572470 10.656341 10.538105 10.487935 10.542126 10.581242 10.409883
224 10.266045 10.247219 10.281342 10.333970 10.283635 10.275189 10.415473
226 10.579565 10.553597 10.492634 10.493050 10.586938 10.626412 10.486066
229  9.343997  9.471088  9.369990  9.286097  9.323401  9.680406  9.396156
233  9.908624 10.021448 10.277496 10.141204 10.002020  9.913636 10.170992
234 10.043988 10.232216  9.917686  9.981744 10.049836 10.269865 10.005186
236  9.450380  9.429155  8.552560  9.174091  9.368967  9.486683  8.777093
245  8.451908  8.154788  8.118803  8.746398  8.584478  7.792349  8.760923
248 10.000160  9.577827 10.212515 10.048799  9.631088  9.363233 10.171949
250  9.529012  9.427144  9.395574  9.498747  9.611597  9.482198  9.450931
251  8.096513  8.040125  4.867534  7.870166  8.734077  8.406485  8.187299
253 10.384709 10.386685 10.335627 10.379939 10.380125 10.334880 10.373460
256  9.864435  9.264165  9.403025  9.340667  9.585346  9.167224  9.488729
257 10.331236 10.362841 10.063649 10.246971 10.322165 10.269033 10.388934
261 10.498360 10.431288 10.376300 10.471468 10.532496 10.405323 10.520509
262  8.793915  8.685247  8.972464  8.963032  8.454466  8.595820  8.746716
269 10.543814 10.550722 10.481308 10.480185 10.536619 10.528142 10.502324
270  9.748353  9.764743 10.061218 10.068663  9.810934  9.613536  9.877503
272 10.272289 10.214495  9.985943  9.969228 10.272462 10.267853 10.169001
274  9.478610  9.407468  9.373734  9.743554  9.435881  9.284520  9.482807
277 10.560723 10.500812 10.652755 10.616756 10.516048 10.494630 10.580124
279 10.370800 10.420643 10.397299 10.341775 10.395497 10.401258 10.356059
280  9.972454  9.680719  9.821029  9.794175  9.887765  9.777924  9.846864
282  9.659120  9.670104  9.412465  9.339085  9.605014  9.545669  9.500619
285 10.194738 10.128390 10.236023 10.320486 10.121498 10.272150 10.221723
288 10.536540 10.454207 10.538582 10.501582 10.453428 10.488882 10.507421
289 10.158401 10.246829  9.994972  9.946212 10.129268 10.183352 10.036225
295  9.013474  8.416267  8.790269  8.771370  8.843326  8.641002  9.209740
306  9.797794  9.493336  9.849823  9.896765  9.536329  9.706377  9.904487
308 10.089178 10.092578 10.090714 10.140889  9.778604  9.984422 10.185277
310  9.418736  9.407304  9.549167  9.629906  9.428753  9.795680  9.549024
311 10.171375 10.208359 10.036838 10.002065 10.155840 10.090506  9.997160
315 10.266776 10.229693 10.151870 10.292451 10.273187 10.321836 10.304911
317 10.393294 10.399037 10.383380 10.403505 10.309952 10.475540 10.394335
320 10.536327 10.391331 10.666650 10.661064 10.644758 10.453717 10.604330
325  9.187686  9.057189  9.066932  9.029298  9.245418  9.298351  9.118883
326 10.505643 10.513172 10.437815 10.500619 10.469313 10.397513 10.411148
331 10.454005 10.430551 10.447584 10.475314 10.404384 10.374022 10.505807
332 10.101067 10.016906  9.898525 10.054748 10.124669  9.847393 10.022026
335 10.117065 10.164466 10.270281 10.189531 10.000705 10.102256 10.247290
336  8.867427  8.348064  8.889308  8.964568  8.204945  8.960853  8.306966
339 10.231279 10.137650 10.221396 10.215777 10.287559 10.284113 10.163079
343 10.115489 10.076137  9.953325 10.076894 10.086850 10.074832 10.034647
348  8.476163  8.471987  9.018090  8.767173  7.862882  8.484463  8.863899
353  9.771384  9.684523  9.932658  9.807582  9.601774  9.718362  9.726810
354  9.784873  9.754581  9.784422  9.954656  9.808627  9.696771  9.651173
355 10.538131 10.460213  8.886824  9.358588 10.625028 10.495626  9.481741
358 10.317846 10.364608 10.328690 10.286775 10.337184 10.284353 10.274154
363  9.769156  9.683090  9.630891  9.985897  9.869776  9.634038  9.567595
364  9.262268  8.891374  8.830543  8.916774  8.987822  8.996033  9.088850
365  9.295325  9.545598  9.599541  9.244742  8.542861  8.977146  9.367686
366  7.039660  7.171657  7.981050  7.732808  7.070724  7.248504  8.331827
372 10.230306 10.246935 10.305145 10.267505 10.184372 10.226295 10.249875
375  9.823741  9.762960  9.650529  9.611396  9.554781  9.807087  9.888120
380 10.388657 10.328396 10.381707 10.330453 10.388534 10.338123 10.367945
381 10.029371 10.109648 10.309386 10.336179  9.947265 10.048929 10.384864
382 10.059508 10.199919 10.161110 10.173515 10.131380 10.111396 10.213359
384  9.028699  8.516993  8.026170  8.571113  8.489616  8.589514  8.338067
387 10.325613 10.224846 10.351884 10.500922 10.214386 10.290178 10.453745
388  8.142063  8.512382  8.752107  8.353497  8.727292  8.700181  8.551788
391  9.801953  9.808077  9.759906  9.876733  9.800901  9.894295  9.974412
392 10.432025 10.358980 10.422430 10.406896 10.393202 10.377234 10.396780
394  9.079890  9.140025  9.213735  9.253879  9.106978  9.279307  9.430840
395 10.354882 10.404323 10.589912 10.518943 10.340903 10.356186 10.502846
396 10.459009 10.407409 10.618910 10.536248 10.311616 10.293670 10.536805
401 10.124990 10.082428 10.246864 10.230090 10.149410 10.074580 10.242742
403  7.336286  4.644391 10.689123  8.327726  7.430114  6.645091  7.873598
409  9.082507  7.644441  8.169903  8.911934  9.133999  8.406038  8.060224
410  9.771327  9.923192 10.019269  9.906184  9.996522 10.133686 10.132176
411  9.267382  9.023167  9.252442  9.090656  9.494767  9.248984  9.234057
413  7.143618 10.663008  6.042633  8.042378  8.236950 10.686475  6.369901
416 10.658318 10.661767 10.480017 10.473337 10.556073 10.635158 10.563802
420 10.209464 10.164274 10.296070 10.218554 10.254884 10.133289 10.321507
422  9.657715  9.660524  9.600489  9.555348  9.416785  9.638219  9.722146
425  7.734121  6.872128  8.303505  8.144098  7.444833  6.628041  8.044947
426  7.313220  8.173575  8.778480  8.455956  8.626765  8.018625  8.852522
430  9.239414  8.973351  9.335209  9.285448  9.172846  9.174402  9.459464
431 10.395803 10.439893 10.399524 10.412772 10.387425 10.370361 10.344642
437 10.497477 10.384524 10.505725 10.509196 10.358790 10.473337 10.487210
439 10.401198 10.400620 10.309319 10.383596 10.412532 10.401562 10.368636
444  8.169620 10.686498 10.621693  8.310169  8.522579  8.657129  8.541105
445 10.151051 10.232180 10.563905 10.517023 10.122904 10.204851 10.466441
446 10.404051 10.298667 10.394733 10.415053 10.315067 10.341710 10.405716
447  6.091310  6.459904  6.622736  8.066521  6.896694  6.269096  8.372861
450  9.791941  9.559588  9.661671  9.638610  9.835155  9.727228  9.586789
451 10.114073  9.964771 10.228249 10.095718 10.229549 10.105938 10.221796
453  9.724959  9.722805  9.510889  9.651301  9.759617  9.699963  9.644393
456  9.747827  9.847235  9.768527  9.684336  9.812742  9.868689  9.774517
457 10.343386 10.435115 10.345317 10.418196 10.470873 10.427654 10.488966
460 10.515750 10.471157 10.549491 10.566124 10.549098 10.501582 10.551925
462 10.641871 10.657565  7.915713 10.680125 10.607525  5.736572  7.950150
463  8.562740  8.809266  9.272470  9.535390  8.480114  7.837554  9.321524
465 10.560204 10.581673 10.558985 10.639239 10.619276 10.605198 10.574951
466 10.152377 10.081592 10.013328 10.011400 10.073821  9.995884  9.915268
468  9.821301  9.814383  9.896110  9.578450  9.631876  9.690109  9.603328
469  6.670766  7.210818 10.659469  6.946014  6.161207  6.302619  6.901737
473 10.669025 10.672183  7.553811  4.948760 10.676416  7.109879  7.499977
474  9.639196  9.595739  9.555772  9.365462  9.595603  9.562264  9.561279
475 10.091335  9.950562  9.787178 10.257484  9.787178 10.269206 10.147022
478 10.141756  9.938130  9.489108  9.596487  9.482426 10.038281  9.531046
479 10.074580 10.141559 10.051433  9.964912 10.116379 10.103362  9.999933
482  9.137555  9.308374  9.284613  8.887515  8.749732  8.780941  9.206031
484 10.579641 10.541281 10.540990 10.455302 10.564525 10.455733 10.561759
486 10.253827 10.473308 10.368636 10.494990 10.236561 10.477288 10.329768
489  9.421978  9.473089  9.475010  9.014569  9.399638  9.382948  9.210140
492  9.539500  9.542015  9.747652  9.685767  9.519368  9.160415  9.875294
499 10.412471 10.098725 10.127351 10.218298 10.127750 10.232647 10.228502
500  8.121480  6.030685  8.260234  8.290293 10.645949 10.687206  8.319474
      G1.T5.4   G2.T1.1   G2.T2.1   G2.T6.1   G2.T3.1   G2.T4.1   G2.T5.1
2   10.438108 10.453630 10.561966 10.461388 10.524897 10.540805 10.663101
4   10.319068 10.124108 10.221323 10.308086 10.175954 10.362430 10.250829
6   10.543946 10.524978 10.599979 10.625198 10.559037 10.551847 10.613271
7   10.235055 10.412051 10.414153 10.347725 10.277462 10.583043 10.526909
8    9.952325  9.640693  9.760887  9.778888  9.642967 10.107978  9.426661
12   8.510571  8.905580  8.506334  7.983440  7.445418  8.739536  8.534050
19   7.891331  8.050703  7.945910  8.482395  8.850947  9.047821  9.280985
21  10.449642 10.368259 10.371395 10.394427 10.347083  9.911555  9.955178
22   9.855242  9.663643  9.680594  9.863915  9.890706  9.841931  9.542805
23  10.431701 10.408587 10.474665 10.412441 10.510478 10.350478 10.401988
26   9.614404  9.674577  9.789927  9.762212  9.728956  9.926374  9.756842
30  10.440156 10.568955 10.512057 10.210457 10.399403 10.301458 10.232216
33  10.531376 10.615726 10.598109 10.619228 10.558362 10.439922 10.523015
36   8.786609  8.274357  7.526718 10.674753  7.062192 10.105162 10.542073
37   9.489335  9.601166  9.362375  9.284241  9.241354  9.011767  9.331938
39   9.179778  9.535535  9.108861  8.904359  9.396654  6.795706  8.377701
41   8.849944  8.891236  9.139381  8.613594  8.092239  7.707962  8.212297
44   9.814000  9.747068  9.554852  9.819780  9.613068  9.881600  9.699902
45   9.944582  9.875911  9.976738 10.108834 10.062071 10.036137 10.168349
50  10.507011 10.460500 10.512900 10.479005 10.480578 10.582916 10.553492
51  10.378541 10.411960 10.418375 10.433204 10.465500 10.553518 10.521291
52   9.976970 10.052726 10.103444 10.079246 10.093901 10.020292 10.060107
56   9.314430  9.044640  9.026538  8.797095  9.202207  9.144735  8.812099
58  10.322264  9.955511  9.903788  9.922996  9.973387  9.986081  9.842729
59   9.872048  9.544667  9.378309  9.117348  9.239511  8.483016  8.237215
62   8.813587  8.956866  8.845921  9.090994  9.234643  8.868413  9.004914
63  10.048843 10.139508 10.020381  9.893134 10.024864  9.955748  9.858176
64  10.271701 10.235772 10.382234 10.249061 10.166006 10.466555 10.392926
68  10.193018 10.362588 10.226151 10.322329 10.054232 10.596360 10.592752
73   8.361241  8.596559  7.750184  6.828712  8.171599  7.403061 10.682216
74  10.504848 10.435732 10.503038 10.284899 10.387918  9.807802  9.700637
76   9.756089 10.070780 10.171031 10.123105 10.180475  9.879912 10.069891
82  10.080797 10.073146 10.204740  9.911704  9.981235  9.698982 10.137334
84  10.618812 10.587115 10.646234  7.267525  6.440947  8.063063  6.990257
87   9.174920  9.517752 10.046158  9.294865  9.277719  9.648337  9.436280
89  10.655941 10.630456  7.186144 10.682927  8.113427  9.994698  5.786897
96  10.430757 10.042336 10.105244 10.314239 10.102666 10.190920  9.797794
103 10.251112 10.416341 10.498305 10.449207 10.458378 10.469596 10.285855
107 10.114761 10.049318 10.170648 10.290178 10.270073 10.215631 10.151129
108  9.811811  9.890098  9.570459  9.388487  9.716194  8.866441  8.931684
113 10.511676 10.588577 10.487852 10.534440 10.551925 10.625587 10.591195
116  9.741380  9.842463 10.016638 10.029680  9.972640  9.797794  9.951373
117  9.036701  9.114490  9.291183  9.676712  9.374158  9.528721  9.601977
119  9.370161  8.479284 10.671951  8.147578  8.196161  7.801391  6.326149
120  5.826000  8.505930  7.966587  8.381603  9.180293  9.287487  8.205218
123  7.363280  7.967973  8.174985  7.479300 10.656883  7.913887 10.614720
130 10.551480 10.556099 10.517348 10.567566 10.588527 10.622010  8.522976
133  9.429396  9.315871  9.090768  8.587279  8.786457  9.044522  8.765302
134  9.099967  9.104202  9.014325  9.313979  9.002947  9.190342  9.163354
139 10.311815 10.417329 10.223613 10.375084 10.424363 10.607426 10.588174
141  9.416378  9.448097  9.169414  9.603665  9.504278 10.000977  9.083189
142  9.200593  8.488999  8.814776  8.812546  8.437934  9.080118  8.558335
144  9.920738  9.830917  9.562545  9.883234  9.870034  9.658290  9.664088
154 10.034516 10.052985 10.050786 10.092661 10.021759 10.028621 10.178084
157  9.908077  9.443355  9.323758  9.508962  9.488805  9.618136  9.491375
158  8.652423  8.963800  8.973858 10.573929  7.270313 10.666674 10.581115
161 10.543366 10.637249 10.611917 10.565428 10.485172 10.679067  7.433667
165  9.702350  9.729015  9.589530  9.093807  9.687878  9.506586  9.338030
168 10.388995 10.379069 10.564809 10.241352 10.333125  9.900182 10.188102
170 10.611129 10.496234 10.525622 10.569623 10.565686  9.731631 10.326367
174 10.362936 10.424095 10.333970 10.262141 10.312613 10.296543 10.120854
176 10.267749 10.107367 10.238172 10.371113 10.192868 10.373522 10.311017
178  8.368461  8.140024  8.723069  8.805525  8.549660  8.819813  8.552174
182  9.503681  9.575469  9.280892  9.553008  9.379239 10.533375 10.296475
183  9.857758  9.818692  9.845382  9.486304  9.540579  9.671051  9.608445
184 10.559971 10.593731 10.533801 10.516455 10.519700 10.512492 10.505916
185  9.347926  9.538132  9.211140  9.237566  9.265113  9.202913  9.166388
187  9.529012  9.730324  9.852720  9.814328  9.900533  9.976552  9.756842
189  9.391244  9.404920  9.445571  9.406894  9.641603  9.361429  9.247829
190 10.012028 10.066201 10.198840 10.206255 10.131539 10.214202 10.171413
191  9.456028  9.791718  9.668967  9.795735  9.633580  9.616872  9.853930
196 10.392987 10.377732 10.390072 10.019447 10.167773 10.125150 10.222341
200  9.035749  9.716736  9.380927  8.948066  9.322061  6.769642  8.690138
202  8.055792  7.892452  8.296796  8.111928 10.687321  8.927447  8.789355
205 10.498746 10.493078 10.458234 10.653110 10.622838 10.495045 10.552944
207  9.107089  9.376363  9.746015  8.985946  8.638171  8.181720  9.079890
208  8.976894  9.213535  9.170039  9.380758  9.502935  9.397732  9.237080
211 10.321573 10.264164 10.488158 10.040245 10.249556  9.988564  9.514585
216 10.105653  9.966275  9.921769  9.925787 10.133607  9.761405  9.764685
219 10.329768 10.325121 10.393416 10.481168 10.274948 10.477316 10.365742
222 10.562871 10.568390 10.561189 10.437170 10.604107  8.687779 10.010277
223 10.485340 10.489884 10.497339 10.452505 10.411539 10.551873 10.462589
224 10.320321 10.409100 10.473704 10.419331 10.474919 10.481224 10.469313
226 10.483130 10.558621 10.572880 10.164351 10.300517 10.075759  9.846653
229  9.503532  9.278373  9.158837  9.266532  9.371098  9.235911  9.087834
233 10.191107 10.247006 10.374522 10.544894 10.484445 10.494159 10.406200
234  9.859483 10.184183 10.176792 10.104958 10.042293 10.175383 10.270697
236  9.120744  9.381769  8.822175  8.679482  9.253112  8.736811  8.369157
245  8.305731  8.829226  8.753845  8.547528  8.689296  8.852522  9.025816
248 10.032101  9.894245 10.177970 10.328625 10.078575 10.262664 10.329049
250  9.518707  9.386308  9.462965  9.376871  9.476007  9.525078  9.417273
251  8.161375  8.683724  8.443331  6.913737  7.630947 10.459267 10.654644
253 10.322625 10.523257 10.452100 10.417239 10.453342 10.409642 10.474693
256  9.523544  9.469700  9.371013  9.480444  9.750802  9.229849  9.144628
257 10.334230 10.424541 10.465386 10.434557 10.430078 10.367913 10.535955
261 10.406019 10.585245 10.390287 10.577401 10.565712 10.508022 10.571778
262  8.329175  8.720297  8.645059  8.626586  7.928406  8.644883  8.549079
269 10.523983 10.538661 10.574798 10.368855 10.470192 10.386068 10.302029
270 10.013238 10.198989 10.368730 10.301492 10.369703 10.382699 10.353384
272 10.072977 10.223467 10.214898  9.933386  9.881242  9.583695  9.832904
274  9.761751  9.587132  9.524932  8.320448  9.191973  8.818334  9.593083
277 10.526695 10.598583 10.517673 10.312314 10.349327 10.444939 10.560308
279 10.320881 10.358124 10.309652 10.380405 10.429162 10.354468 10.380281
280  9.846917  9.822820 10.084725  9.509556  9.584865  8.798304  9.665294
282  9.455089  9.560081  9.632990  9.738790  9.593083  9.631022  9.471242
285 10.245232 10.127231 10.098643 10.094315 10.146983 10.081466 10.227128
288 10.395222 10.597984 10.512138 10.461302 10.324564 10.400985 10.331594
289 10.056423 10.060748 10.194065 10.260777 10.216362 10.217787 10.181233
295  9.054739  8.911395  9.354700  7.334982  7.741099 10.310585 10.282711
306  9.953658  9.797738  9.777187  9.432523  9.575608  9.659312  9.586789
308  9.921622  9.923045  9.859692  9.943045  9.700453  8.293550  9.342771
310  9.448963  9.397898  9.303193  8.919453  9.224243  9.169831  9.143559
311  9.940350 10.122904 10.158207 10.170533 10.299845 10.123225 10.235055
315 10.281307 10.080713 10.241637  9.864643 10.021182  9.743201  9.917637
317 10.427920 10.340613 10.285070 10.251112 10.228140 10.342291 10.300383
320  8.194229 10.532549 10.648230 10.631302 10.640867 10.665087 10.566382
325  9.117457  9.477692  9.741439  9.763823  9.763536  9.849031  9.737669
326 10.481645 10.473025 10.488938 10.556125 10.512927 10.635423 10.499187
331 10.496621 10.542627 10.540620 10.538979 10.491913 10.505752 10.594357
332 10.016548 10.169767 10.218262  9.778831  9.865682  9.401126  9.220687
335 10.178008 10.202629 10.203148 10.310452 10.334685 10.368604 10.298801
336  8.718337  7.371489  8.200837  8.501876  8.712431  8.886547  8.307213
339 10.303069 10.349006 10.385111  9.881344  9.932172  9.497697  9.443513
343 10.096048 10.154130 10.216143 10.313343 10.236884 10.146434 10.073399
348  8.412943  8.956351  9.094817  9.261224  9.081029  9.560293  9.419547
353  9.886087  9.600963  9.535246  9.614538  9.718422  9.623377  9.644069
354  9.889642  9.626284  9.538996  9.663389  9.914378  9.709903  9.506214
355  9.299541  8.608130  8.815815  6.345636  8.294300 10.137096 10.514339
358 10.276292 10.367222 10.444095 10.384431 10.439747 10.361830 10.315266
363  9.716314  9.987921  9.786336  9.579625  9.919705 10.483578  9.980911
364  8.797246  8.984819  8.335192  9.200290  8.272826  9.248888  9.063116
365  8.759512  9.172223  8.094989  8.694837  8.779250  8.580919  8.822912
366  8.001690  8.211483  8.410943  8.187855  8.473450  8.695507  8.643121
372 10.229693 10.176259 10.189794  9.959679 10.046072  9.993054  9.925151
375  9.677026  9.725258  9.862092  9.053219  9.596011  7.543803  8.902456
380 10.296644 10.376487 10.374147 10.295732 10.340225 10.225788 10.348590
381 10.408376  9.790991  9.858647 10.003650 10.142504 10.242457 10.183200
382 10.240745 10.275327 10.326170 10.329735 10.395008 10.281444 10.341710
384  8.573574  8.689633  8.800114  8.927977  9.253879  9.568854  8.911395
387 10.443921  9.953039 10.150465 10.188666 10.283635 10.181687  9.839642
388  8.387768  8.433377  8.841304  9.206533  8.978030  8.956093  9.274066
391  9.892224  9.872048  9.880731  9.634169  9.658546  9.354268  9.405660
392 10.399829 10.415922 10.383844 10.490996 10.529720 10.510587 10.408074
394  9.333354  9.111845  8.974618  9.150590  9.261889  9.409519  9.295049
395 10.389734 10.435879 10.459124 10.545315 10.517213 10.636961 10.568904
396 10.591773 10.530922 10.491857 10.588224 10.524064 10.660360 10.615113
401 10.280004 10.185013 10.193916  9.934599 10.047415 10.026634  9.982391
403  8.332549 10.633184  8.098339  7.957877  7.539559  8.187577  6.396930
409  8.386629  9.239316  8.139732  7.711101 10.688758 10.602045  8.972971
410 10.038368  9.812742  9.824282  9.941409 10.259272  9.969977  9.946403
411  9.033484  9.239802  9.263028  9.435083  9.161255  9.282940  9.448806
413  7.749322  8.504918  7.418181 10.551559 10.603635 10.487963 10.327578
416 10.541545 10.613566 10.494547 10.670443 10.545394 10.234373 10.395467
420 10.274913 10.302264 10.303773 10.349198 10.286571 10.398336 10.317780
422  9.732165  9.477386  9.471550  9.557894  9.303740  9.515690  9.465912
425  7.877776  8.517193  8.615590  8.586719  8.921858  8.412943  7.785305
426  8.398410  8.757626  9.073718  9.104535  9.127719  8.858653  8.617220
430  9.481359  9.951849  9.206834  9.098626  8.893023  9.165343  9.094817
431 10.380467 10.449671 10.421239 10.396322 10.598333 10.525649 10.419241
437 10.390871 10.424452 10.365679  9.948748 10.142898  9.932464 10.104263
439 10.399524 10.392589 10.459698 10.251359 10.355136 10.386130 10.412021
444  8.454253  7.997663  8.496174  8.767329  8.006368  8.208492  8.618305
445 10.513661 10.119123 10.199621 10.107978 10.012342 10.174926 10.231315
446 10.422995 10.364734 10.450221 10.156927 10.202258  9.927985 10.043815
447  8.385945  8.075894  8.685754 10.625829  7.278629 10.569109  7.630461
450  9.655603 10.043858 10.102994  9.869776  9.904937  9.553433  9.881293
451 10.196791 10.197164 10.261372  9.741792  9.995428  9.513182  9.507180
453  9.536257  9.624435  9.788638  9.824120  9.839589  9.891314  9.779171
456  9.735069  9.881395  9.889135  9.934356 10.074200  9.781828  9.877092
457 10.487545 10.383627 10.284455 10.277462 10.407530  9.500245 10.341484
460 10.495515 10.596760 10.567952 10.342258 10.462389 10.344834 10.305614
462  3.555348 10.677085 10.647494 10.582764 10.603461 10.603387 10.624955
463  9.157572  8.866017  8.117312  8.798153  9.179675  9.465835  8.485909
465 10.641536 10.644091 10.605223 10.597210 10.602840 10.588527 10.572444
466 10.062370  9.981975  9.977574 10.017084 10.147022 10.462989 10.095718
468  9.503010  9.793840  9.573524  9.798960  9.720946 10.334035  9.782788
469  5.913503  6.396930 10.674429 10.661064 10.639982  5.424950  7.069023
473  7.109879 10.667792  3.931826  6.651572 10.569520  8.458292  7.040536
474  9.498147  9.484405  9.554426  9.795345  9.687382  9.609787  9.699840
475 10.018645  9.166597  9.515101  9.474856  9.777357 10.209095  8.925321
478  9.280892  9.446677  9.172742  9.676399  9.624963 10.682950  9.631416
479  9.975808 10.087142 10.058609 10.141323 10.133050 10.046808 10.075843
482  8.908695  9.064389  9.240967  8.944811  8.906664  9.621058  8.658519
484 10.515858 10.554405 10.585372 10.457804 10.448686  9.828063  9.708202
486 10.469738 10.391423 10.288852 10.390133 10.329180 10.030561 10.240103
489  9.289336  9.018211  9.559870  9.655795  9.544811  9.554143  9.728539
492  9.611797  9.971380  9.884101  9.957928  9.665230  9.947696  9.882723
499 10.155918  9.809342 10.086767 10.061346  9.973760  9.549951  9.763363
500  8.615046 10.662399  6.811244 10.669467 10.637273  8.644354  8.139732
      G2.T1.2   G2.T2.2   G2.T6.2   G2.T3.2   G2.T4.2   G2.T5.2   G2.T1.3
2   10.588628 10.576126 10.596085 10.426024 10.526802 10.525729 10.592501
4   10.305848 10.323513 10.642014 10.608341 10.549307 10.621620 10.587241
6   10.632894 10.590642 10.598807 10.538555 10.646282 10.608020 10.597409
7   10.405050 10.590742 10.460729 10.553675 10.409944 10.470646 10.405081
8    9.524494  9.607370  9.099185  9.236593  9.607034  9.493788  9.463276
12   8.042056  8.073403  8.512984  7.397562  8.337349  8.058327  8.274102
19   9.223454  9.422625  8.470730  9.009325  8.951829  9.174920  8.867850
21  10.176868  9.816349 10.370079 10.046375 10.401137 10.274672 10.340451
22   9.759444  9.951516  9.714021  9.700637  9.800125  9.867757  9.815858
23  10.439513 10.460615 10.408044 10.461359 10.445521 10.430019 10.376237
26   9.706316  9.634889  9.957170  9.851036  9.773493  9.948509  9.882366
30  10.209758 10.315034 10.047891 10.091501 10.039983 10.233403 10.131658
33  10.550669 10.459009 10.491663 10.472799 10.492190 10.417957 10.481476
36  10.495211 10.537044 10.327480 10.383813 10.345252 10.554849 10.246687
37   9.092007  9.353488  9.380421  9.344784  9.040145  9.343734  9.501815
39   8.128585  8.426612  7.581720  7.036148  7.545390  7.743703  8.003029
41   8.155649  7.040536  8.467793  8.170186  7.987185  8.420682  8.053569
44   9.766407  9.680031 10.111639  9.929155  9.933823  9.979893 10.229043
45  10.119606 10.175116 10.127990 10.094851 10.062668 10.102051 10.039983
50  10.474072 10.467351 10.401988 10.572060 10.652519 10.563052 10.553022
51  10.483578 10.488465 10.305614 10.627915 10.530815 10.454322 10.470788
52  10.041944 10.070442 10.131061 10.126551 10.011220  9.953753  9.957313
56   8.135054  8.644178  8.630522  8.706325  6.952729  7.980366  8.387085
58   9.933677 10.013238  9.825256 10.044466  9.914131  9.981652  9.936148
59   5.613128  8.074960  5.407172 10.665181  8.232440  8.457655  8.958669
62   9.109193  9.056490  9.392412  8.966739  9.239608  9.211140  9.302920
63   9.907231 10.051606  9.960057  9.948604  9.772125  9.884967  9.895002
64  10.378323 10.389488 10.293602 10.340484 10.457660 10.245764 10.323579
68  10.558154 10.632822  8.833754  8.044305  9.319015  8.423102  9.087268
73  10.626703 10.649203 10.683844  5.170484 10.678376 10.678030 10.683729
74   9.448727  9.657843  9.468388 10.093116  9.945349  9.538924  9.614538
76   9.903987 10.074537 10.112086  9.967213 10.045204 10.046548 10.242065
82   9.898123  9.989252  9.904687  9.841187 10.017396  9.902787 10.060790
84   7.195187  7.847372 10.666557 10.689465  7.234177  6.629363 10.649654
87   8.861634  9.183277  9.471473  9.252729  9.102644  9.016027  9.046173
89   6.840547 10.684897 10.308319 10.369483 10.432291 10.470278 10.508486
96  10.044813 10.277462  9.813727  9.874059 10.200959 10.202814  9.922211
103 10.357902 10.309985 10.320980 10.381490 10.358600 10.348718 10.380312
107 10.187500 10.148236 10.272634 10.266532 10.248211 10.162770 10.175802
108  8.657651  8.843471  8.823353  7.654917  8.503905  8.743532  9.170560
113 10.615236 10.636793 10.605223 10.652590 10.607550 10.626873 10.618714
116  9.967166  9.923290  9.824985  9.904687 10.012342  9.870448 10.045985
117  8.890824  8.832442  9.046644  9.901486  9.223257  9.317130  9.269552
119  8.386629  8.290544  3.332205  8.379309  8.037866  8.554104 10.668653
120  7.604396  8.883502  8.094378  8.367997  7.614805  8.355145  7.977282
123 10.539244 10.615137 10.609502 10.601871 10.663873 10.600253 10.643280
130  9.626943  8.959055  9.224145  9.516795  9.531046  9.601707  8.304742
133  8.693832  8.982184  8.985320  8.969923  8.471987  8.697346  9.185535
134  9.425290  9.257224  9.429235  9.562897  9.312265  9.540148  9.016877
139 10.377577 10.547733 10.444124 10.580861 10.478977 10.615726 10.395344
141  9.646593  9.377210  9.317130  9.286931  9.593355  9.491602  9.281730
142  8.750049  8.694502  8.865453  8.851234  8.703839  8.992309  8.857942
144  9.812085  9.858595  9.625888  9.642772  9.873853  9.746073  9.654385
154 10.237421 10.190582 10.171222 10.078365 10.149527 10.156035 10.113465
157  9.279027  9.581352  9.366404  9.798294  9.307104  9.362804  9.462732
158 10.305714 10.473930  9.871842 10.285240  9.701065  9.967307  9.780585
161  7.224025  7.928046  8.799360  7.782390  9.619133  8.876405  8.823206
165  9.195633  9.141847  9.362804  9.439943  9.162829  9.182969  9.231613
168 10.026280 10.015342 10.207510 10.083682 10.243311  9.975483 10.032233
170 10.458550 10.359329 10.499793 10.514719 10.539853 10.491108 10.457488
174 10.039983 10.206366 10.214679 10.163426 10.144785 10.355900 10.019269
176 10.322264 10.267401 10.350414 10.327054 10.447380 10.385605 10.309119
178  8.727940  8.671458  8.422443  8.716863  9.082280  8.955319  8.487146
182 10.433822 10.232432 10.603114 10.408738 10.561992 10.617882 10.301727
183  9.357639  9.321076  9.466300  9.219895  8.774004  9.295233  9.559517
184 10.397147 10.500949 10.411750 10.382482 10.336600 10.410305 10.438284
185  9.176784  9.453600  8.458504  9.574983  8.618124  8.859079  8.512783
187  9.429556  9.697877  9.680531  9.900433  9.474703  9.728598  9.947457
189  9.271341  9.384714  9.200795  9.052868  9.228279  9.433884  9.363834
190 10.248813 10.073399 10.113424 10.123867 10.225644 10.187237  9.970866
191  9.893589  9.904637 10.196530 10.075043 10.163464  9.919312  9.911753
196 10.031969 10.031045  9.924711 10.051261  9.977760 10.100451 10.019001
200  8.074026  8.526549  8.629986  8.390723  8.637107  8.296297  8.623174
202  8.777401  8.385489  8.154500  8.701513  8.477412  8.039480  7.796058
205 10.676785 10.657000 10.579514 10.546420 10.605198 10.620034 10.560774
207  8.259458  8.872908  8.715388  8.922658  8.664751  8.257645  8.470521
208  9.505470  9.474626  9.523325  9.422949  9.630234  9.610793  9.224440
211  9.519955  9.485013  9.655731  9.785042  9.692149  9.502935  9.512221
216  9.594241  9.845753  9.739084  9.822928  9.540004  9.907480  9.625096
219 10.477429 10.347789 10.467095 10.440712 10.507366 10.442871 10.533722
222 10.252700 10.073737 10.162963  9.873544 10.355677 10.156073 10.115611
223 10.386870 10.448483 10.417179 10.526320 10.438020 10.446625 10.386006
224 10.353193 10.399220 10.345510 10.496455 10.312214 10.353320 10.407137
226  9.293118  9.637241  9.332823  9.449121  9.226607  9.382612  9.450066
229  9.220984  9.340667  9.089753  9.091106  9.494918  9.378817  9.318118
233 10.159369 10.385142 10.286946 10.615775 10.263572 10.366057 10.302029
234 10.204592 10.117106 10.216362 10.246439 10.121458 10.053587 10.307151
236  8.314097  8.504716  8.868554  8.761080  8.466321  8.778172  8.619208
245  7.868637  8.090096  8.493310  8.562358  8.373785  8.435115  8.762333
248 10.237099 10.013821 10.157199 10.253264 10.420017 10.257940 10.004192
250  9.341544  9.366917  9.153770  9.325810  9.121509  9.339701  9.277438
251 10.605248 10.625587 10.592074 10.625004 10.641560 10.614327 10.648563
253 10.491496 10.434968 10.527874 10.545894 10.375832 10.471100 10.472120
256  9.208739  9.193398  9.376533  8.865876  9.290260  9.164401  9.103868
257 10.499518 10.456597 10.462818 10.435673 10.453572 10.412081 10.455446
261 10.624906 10.531429 10.417029 10.544868 10.583929 10.517916 10.488855
262  8.623713  8.334231  8.597113  7.871311  8.358666  8.437717  8.371011
269 10.300517 10.279798 10.383503 10.307285 10.128749 10.340710 10.367567
270 10.598009 10.456050 10.260112 10.062370 10.335335 10.331431 10.260112
272  9.541297  9.576857  9.772524  9.846388  9.570948  9.476084  9.820378
274  9.257224  9.146974  9.202611  9.420034  8.870242  9.145695  8.662505
277 10.313973 10.444357  9.672627  9.479298  9.776279  9.583420  9.983546
279 10.433616 10.473337 10.402261 10.495847 10.375770 10.418554 10.393845
280  9.404590  9.544095  9.587475  9.687320  9.657459  9.638023  9.701004
282  9.778604  9.512960  9.419709  9.777584  9.610391  9.618402  9.450380
285 10.094356 10.275224 10.106306 10.063137 10.097944 10.187500 10.185654
288 10.440712 10.283737 10.218955 10.116379 10.344352 10.315200 10.377078
289 10.181157 10.188779 10.121337 10.177210 10.209464 10.297319 10.140771
295  9.958496 10.114437 10.192943 10.224375 10.342903 10.240888 10.236131
306  9.360741  9.494090  9.705098  9.572759  9.481664  9.449357  9.657139
308  9.667195  9.395574  9.247925  9.061608  9.653487  9.512221  9.414179
310  8.963288  9.479986  8.727778  8.914492  8.772300  9.232982  9.275847
311 10.235737 10.284250 10.217787  9.942612 10.199101 10.241280 10.158556
315  9.720466  9.899429  9.964018  9.756321  9.652909  9.761463 10.004057
317 10.304007 10.333385  9.991590 10.245658 10.204148 10.397116 10.248813
320 10.616560 10.581267 10.626242 10.644877 10.579158 10.613394 10.599655
325  9.670672  9.754233  9.779284  9.857025  9.591240  9.717278  9.702900
326 10.498139 10.606635 10.522073 10.514285 10.553597 10.477429 10.441529
331 10.562406 10.498084 10.581521 10.499022 10.601199 10.512845 10.617540
332  9.257415  9.273221  9.424968  9.441611  9.434603  9.510223  9.523325
335 10.235772 10.407047 10.251571 10.319761 10.236525 10.332734 10.327349
336  8.649449  8.914088  8.316545  8.170469  8.865312  8.963928  8.513988
339  9.114820  9.135293  9.096500  9.100302  9.125109  9.118225  9.227984
343 10.285377 10.160569 10.160685 10.319068 10.140139 10.218408 10.082387
348  9.493864  9.285170  8.962648  9.006877  9.495895  9.333708  9.002701
353  9.499197  9.700269  9.613803  9.630037  9.538276  9.631219  9.720766
354  9.607975  9.721546  9.371438  9.768641  9.458606  9.485393  9.398561
355 10.458722 10.358663 10.241566 10.306015 10.368227 10.268721 10.257203
358 10.397665 10.357489 10.401653 10.377016 10.353544 10.397086 10.350127
363  9.934065  9.924809 10.112126 10.088514  9.951182 10.034954 10.026103
364  8.742734  8.140898  7.392032  8.292799  8.783856  7.679714  6.966024
365  8.899458  8.869258  9.151757  8.928508  9.182661  9.402695  8.483223
366  8.550821  8.558911  8.714239  7.954723  8.516793  8.418036  8.413165
372  9.945828  9.936003  9.872564  9.997934  9.984007 10.127511  9.955036
375  7.929126  8.728102  8.459352  8.669399  8.716208  8.766706  7.656810
380 10.305413 10.362809 10.226947 10.219575 10.289566 10.274396 10.247999
381 10.059807  9.947983 10.399220 10.013776 10.182898 10.174240 10.238351
382 10.331953 10.266741 10.305145 10.326465 10.337411 10.237779 10.334913
384  9.029058  8.570544  9.538852  8.874728  9.362632  8.945984  9.433244
387  9.976877 10.019447  9.739143  9.962181  9.897771  9.840814  9.922113
388  9.297160  9.121728  8.902456  9.035511  9.081370  8.921725  9.098179
391  9.214432  9.606832  9.206834  9.163773  9.372374  9.583558  9.058820
392 10.426410 10.442697 10.515777 10.477288 10.441705 10.465956 10.382699
394  9.230437  9.317938  9.335386  9.365976  9.324205  9.361773  9.344696
395 10.439074 10.478780 10.586534 10.607228 10.490357 10.518051 10.540302
396 10.498719 10.511866 10.486206 10.579311 10.593680 10.540170 10.549805
401  9.904986  9.972874  9.999843  9.722086  9.692087  9.939916  9.949034
403 10.608983  5.942799 10.646377 10.622668 10.682400  6.687109 10.653488
409  9.033006  8.865594  8.819074  9.055790  8.836083  8.924789  9.448885
410  9.759733  9.812304  9.945876 10.045421  9.947696 10.054490 10.020737
411  9.495670  9.311633  9.334591  9.231025  9.591513  9.350972  9.172015
413 10.295901 10.329833 10.551507 10.576585 10.475258 10.379722 10.588729
416  8.355615 10.517240  9.086024  7.780303  9.564723  7.551187  8.800415
420 10.273982 10.164582 10.344095 10.456424 10.374772 10.291467 10.447409
422  9.369734  9.485317  9.729372  9.575816  9.570041  9.447466  9.777017
425  8.926518  8.415603  8.211754  8.429018  8.728750  7.340187  8.715552
426  9.125327  8.811950  8.697179  8.890824  9.049819  9.063347  8.960468
430  8.851520  8.431853  9.058587  9.220192  8.539346  8.811652  9.052985
431 10.354340 10.489996 10.456970 10.504300 10.412652 10.468034 10.397665
437  9.929594  9.967870  9.699595  9.532206  9.859901  9.774233  9.857758
439 10.303639 10.349359 10.326858 10.257028 10.172178 10.252629 10.236884
444  8.018296  8.768263  8.509967  8.258681  8.392537  8.155075  8.271293
445 10.201293 10.208727 10.142386 10.138481 10.318738 10.116944 10.241673
446  9.816949  9.871636  9.748937  9.923584 10.040768  9.771726  9.948748
447 10.559763 10.663849 10.376424 10.504026 10.401805 10.535132 10.553466
450 10.004644  9.815858 10.059636  9.968010  9.731631  9.933095  9.844321
451  9.078864  9.283498  9.335739  9.619399  9.358588  9.200997  9.375855
453  9.798516  9.776165  9.802562  9.804054  9.743319  9.832528  9.837241
456  9.966744  9.830917  9.842463 10.188027  9.952373  9.829572  9.696894
457 10.338544 10.378417 10.239067 10.322954 10.223358 10.463960 10.084975
460 10.207400 10.261442 10.202258 10.218043 10.504081 10.239317 10.319728
462 10.591949 10.642516 10.377265 10.612951 10.540884 10.592677 10.588199
463  8.120589  9.040975  7.620705  8.781862  7.860956  8.840870  6.234411
465 10.512954 10.549517 10.519241 10.577732 10.575973 10.520240 10.582130
466 10.122663 10.286366 10.189193 10.177400 10.090423 10.299811 10.193841
468  9.892477  9.917045 10.055651  9.896463  9.920984  9.959206  9.944102
469 10.627043  5.852202  6.841615  7.334329 10.622302  5.855072  7.627057
473  6.274762 10.639047 10.676139 10.654031 10.679918 10.640604  5.141664
474  9.845488  9.689613  9.649047  9.837401  9.779624  9.775313  9.551160
475  9.478151  9.633907  8.163941  8.925188  9.320629  9.641408  9.327590
478  9.639001  9.567035  9.875345  9.963594 10.012790 10.170150  9.815912
479 10.172636 10.162809 10.149371 10.081759 10.227128 10.186371 10.153312
482  8.022897  8.820699  8.775240  8.745284  8.561593  9.095603  8.337588
484  9.493788  9.755683 10.068324  9.969369 10.083139 10.013283  9.749112
486 10.404536 10.089884 10.167197  9.948365 10.330388 10.183918 10.105407
489  9.856291  9.642772  9.546241  9.206533  9.881089  9.899228  9.702044
492  9.973433  9.893488  9.709903  9.865890  9.868068  9.900583  9.664278
499 10.145296  9.871429 10.080336 10.128988 10.269692 10.196269 10.306583
500  6.882437  7.387090  8.108623  7.754910 10.656412 10.674244  7.799753
      G2.T2.3   G2.T6.3   G2.T3.3   G2.T4.3   G2.T5.3   G2.T1.4   G2.T2.4
2   10.583271 10.514014 10.381738 10.571650 10.502159 10.524897 10.524360
4   10.650578 10.541148 10.647257 10.574133 10.561655 10.175954 10.503066
6   10.581927 10.623325 10.577121 10.652282 10.583043 10.559037 10.558102
7   10.491274 10.394090 10.387795 10.456827 10.445318 10.277462 10.486234
8    9.478228  9.639457  9.644652  9.618070  9.798738  9.642967  9.521055
12   8.220672  7.769801  6.318968  8.473659  7.483807  7.445418  6.722630
19   8.700348  8.777710  8.984568  9.024613  8.524963  8.850947  8.926650
21  10.295394 10.229188 10.253616 10.202925 10.201664 10.347083 10.050355
22   9.732343  9.722685  9.776620  9.667575  9.872048  9.890706  9.790991
23  10.426439 10.472431 10.341323 10.392987 10.443571 10.510478 10.401471
26   9.806040  9.806205  9.806536  9.922898  9.857182  9.728956  9.911208
30  10.388749 10.027518 10.058267 10.035042 10.243347 10.399403 10.192980
33  10.520347 10.504848 10.371427 10.506464 10.478836 10.558362 10.568055
36  10.334815 10.449410 10.538847 10.453428 10.449439  7.062192 10.607129
37   9.571157  9.290998  9.206634  9.412056  9.329101  9.241354  9.243582
39   8.510773  8.521982  8.282736  8.524566  8.885718  9.396654  8.565412
41   8.472614  8.231376  8.316300  8.004700  8.105308  8.092239  7.418781
44  10.110827  9.895052  9.768183 10.137096 10.218554  9.613068  9.874574
45  10.068451 10.059765  9.905486 10.141362 10.025749 10.062071 10.196679
50  10.507913 10.606164 10.421835 10.596685 10.474269 10.480578 10.596610
51  10.459698 10.482822 10.577528 10.340484 10.598583 10.465500 10.544130
52  10.063350 10.142819 10.052037 10.124589 10.094025 10.093901 10.100985
56   8.282230  7.671827  7.687080  8.025516  8.108021  9.202207  8.343792
58   9.830164 10.144785  9.799459  9.908027  9.986587  9.973387 10.085392
59   8.972844  9.556197  9.189831  9.393079  9.151439  9.239511  9.457122
62   9.188095  9.153876  8.933532  9.186867  9.185228  9.234643  9.202510
63   9.988839  9.958638  9.815639  9.893892  9.808737 10.024864  9.949416
64  10.409672 10.410034 10.323611 10.206107 10.300181 10.166006 10.223939
68   9.213635  9.490771  9.320718  9.905236  9.812523 10.054232  9.967495
73  10.678606 10.678123 10.655587 10.634797 10.678030  8.171599 10.675792
74   9.765317  9.885273  9.987921  9.878067  9.780642 10.387918  9.972407
76  10.078449 10.242813 10.005096 10.149449 10.147688 10.180475 10.212699
82  10.186860  9.904637 10.096873 10.159331 10.121377  9.981235 10.075085
84  10.678652 10.673411  7.772753 10.682583  6.949856  6.440947  6.762730
87   9.037652  9.124238  8.946896  9.116908  9.298443  9.277719  9.037177
89  10.386315 10.589106 10.564938 10.631229 10.552840  8.113427 10.679665
96   9.906732 10.217714  9.951039  9.952421 10.244699 10.102666 10.226078
103 10.408707 10.353257 10.198580 10.396994 10.380529 10.458378 10.443250
107 10.126951 10.301995 10.246935 10.257028 10.218882 10.270073 10.091004
108  8.851520  9.609049  8.539150  9.493035  9.043223  9.716194  9.590351
113 10.616756 10.605421 10.603263 10.578954 10.565118 10.551925 10.586332
116  9.773948  9.871274  9.959679  9.728539  9.980911  9.972640  9.816403
117  9.216024  9.464517  9.236788  9.596487  9.431883  9.374158  9.776165
119  7.404279  8.411833 10.665928  7.848543  6.992096  8.196161  8.838697
120  7.688913  7.492760  8.348538  8.420903  7.620215  9.180293  8.748622
123 10.681619 10.664597 10.587922 10.646305 10.637225 10.656883 10.676093
130  8.092851 10.564266  8.382061  7.157735 10.637561 10.588527 10.537787
133  9.043577  8.603004  8.751316  8.785845  8.923191  8.786457  8.933532
134  9.220885  9.199381  9.457513  9.324562  9.142169  9.002947  9.182969
139 10.396383 10.420822 10.427476 10.412682 10.503395 10.424363 10.463160
141  9.088850  9.772410  9.641278  9.030496  9.410747  9.504278  9.930129
142  8.948456  9.214532  8.526549  8.958154  8.897819  8.437934  8.857515
144  9.612333  9.932755  9.625492  9.696586  9.600963  9.870034  9.666055
154 10.230883 10.239102 10.250935 10.174697 10.213249 10.021759  9.997979
157  9.367173  9.282289  9.604677  9.397815  9.495219  9.488805  9.487593
158 10.148940 10.158788  9.892477 10.201701  9.849929  7.270313 10.300551
161  8.913147  9.581559  9.347752  9.595875  9.658737 10.485172  9.852247
165  9.374328  9.116469  8.799511  9.067855  9.318387  9.687878  8.785845
168  9.997114 10.176145 10.070018 10.079078 10.090962 10.333125 10.266254
170 10.475427 10.410907 10.516509 10.381583 10.470448 10.565686 10.500537
174 10.027959 10.064500 10.331268  9.987645 10.089677 10.312613 10.229513
176 10.278184 10.349743 10.380187 10.376985 10.337767 10.192868 10.406473
178  8.720950  8.710455  8.968906  8.458716  8.669743  8.549660  8.411610
182  8.028455 10.517592 10.409160 10.088431 10.604479  9.379239 10.020915
183  9.548668  9.447387  9.018574  9.555135  9.550164  9.540579  9.636914
184 10.431937 10.398550 10.495073 10.486569 10.451464 10.519700 10.454639
185  9.077494  8.919854  8.912743  8.571871  8.805975  9.265113  9.107643
187  9.694740  9.450538  9.850614  9.670231  9.908326  9.900533  9.592332
189  9.261129  9.432043  9.391995  9.344434  9.271530  9.641603  9.308646
190 10.103526 10.133885 10.289838 10.207547 10.115530 10.131539 10.116783
191  9.998025  9.941939 10.020426 10.164389 10.120653  9.633580 10.033199
196 10.180892  9.947552 10.016236 10.041204 10.099712 10.167773  9.781998
200  8.697179  7.873598  8.251403  8.616314  8.246696  9.322061  7.658228
202  8.162801  8.508959  8.982687  7.886833  8.601350 10.687321  6.947937
205 10.518187 10.678007 10.633232 10.641656 10.607129 10.622838 10.648990
207  8.484877  8.181441  8.516593  8.966994  8.997023  8.638171  9.107421
208  9.436838  9.499272  9.336532  9.488805  9.303557  9.502935  9.510445
211  9.620262  9.691655  9.535752  9.697877  9.630431 10.249556  9.706864
216  9.726750  9.754175  9.836011  9.692705  9.754465 10.133607  9.826336
219 10.581394 10.563853 10.528249 10.410185 10.501829 10.274948 10.442522
222  9.979708 10.216289 10.221759 10.197164 10.313111 10.604107 10.332311
223 10.419599 10.443979 10.403899 10.405353 10.469227 10.411539 10.412081
224 10.344062 10.324564 10.428630 10.338285 10.366435 10.474919 10.495405
226  9.787066  9.434923  9.490696  9.445175  9.655859 10.300517  9.894043
229  9.250714  9.318477  9.179159  9.199381  8.959954  9.371098  8.988571
233 10.373554 10.444153 10.271943 10.428482 10.467636 10.484445 10.598059
234 10.295766 10.202962 10.198915 10.059807 10.179413 10.042293 10.117590
236  8.625330  8.636042  7.225481  9.139167  8.472614  9.253112  8.818778
245  8.856661  8.518792  9.155356  8.773694  9.156201  8.689296  8.811950
248  9.981467 10.383936 10.409492 10.149175 10.290042 10.078575 10.273084
250  9.274160  9.295325  9.052633  9.176163  9.432764  9.476007  9.364434
251 10.676393 10.649180 10.611523 10.660970 10.669211  7.630947 10.644734
253 10.461588 10.464588 10.435350 10.477654 10.424363 10.453342 10.451233
256  8.733111  9.366147  8.921458  9.083983  9.277064  9.750802  9.180190
257 10.345574 10.389149 10.373522 10.431672 10.426854 10.430078 10.445666
261 10.433910 10.549596 10.640843 10.509278 10.667023 10.565712 10.452302
262  8.729397  8.852236  7.324490  8.279190  8.519790  7.928406  8.585039
269 10.362715 10.293568 10.077105 10.415982 10.262315 10.470192 10.264443
270 10.407319 10.496925 10.379318 10.537972 10.169691 10.369703 10.413523
272  9.898425  9.657971  9.821301  9.891617  9.607101  9.881242  9.608244
274  9.090881  7.878155  8.598404  8.876126  8.789508  9.191973  8.870944
277  9.955368 10.421954 10.193579 10.247893 10.257519 10.349327 10.461845
279 10.356091 10.393355 10.434116 10.392068 10.289192 10.429162 10.424570
280  9.854035  9.435083  9.528794  9.646658  9.714021  9.584865  9.527557
282  9.586583  9.743847  9.689675  9.623708  9.778491  9.593083  9.556409
285 10.205257 10.090921 10.078910 10.074242 10.070738 10.146983 10.140928
288 10.348910 10.475314 10.320123 10.463389 10.399737 10.324564 10.383070
289 10.163310 10.214495 10.234373 10.192494 10.216508 10.216362 10.091833
295 10.347628 10.301492 10.373210 10.374022 10.392098  7.741099 10.528008
306  9.567035  9.570320  9.321345  9.604475  9.410256  9.575608  9.452109
308  9.478381  9.708749  9.776903  9.455011  9.535318  9.700453  9.649820
310  9.258082  8.916774  9.142062  8.885303  9.222170  9.224243  9.187072
311 10.136185 10.179527 10.198170 10.043901 10.172751 10.299845 10.101190
315  9.777811  9.780189  9.731097  9.951134  9.815093 10.021182  9.807307
317 10.370205 10.178806 10.339061 10.214862 10.328003 10.228140 10.243098
320 10.596410 10.635783 10.543287 10.600278 10.561033 10.640867 10.589384
325  9.593014  9.724480  9.598456  9.840335  9.607841  9.763536  9.849295
326 10.457603 10.544762 10.523715 10.563207 10.523741 10.512927 10.560697
331 10.567000 10.531536 10.468517 10.568338 10.617589 10.491913 10.542812
332  9.493638  9.453287  9.152181  9.416460  9.511555  9.865682  9.569831
335 10.307852 10.228068 10.084308 10.304911 10.245658 10.334685 10.416161
336  8.065265  8.843615  8.406262  8.584852  8.584852  8.712431  8.702344
339  9.375855  9.215726  8.998137  9.594309  9.324294  9.932172  9.274441
343 10.243560 10.173477 10.091335 10.168157 10.240353 10.236884 10.231676
348  9.492130  9.248021  9.657587  9.091219  9.438432  9.081029  9.255218
353  9.678405  9.832689  9.588571  9.720586  9.686761  9.718422  9.855085
354  9.707777  9.771270  9.394161  9.660651  9.618402  9.914378  9.834834
355 10.380281 10.239603 10.320552 10.179565 10.323808  8.294300 10.404899
358 10.361419 10.369012 10.328951 10.380715 10.380343 10.439747 10.403808
363 10.139389  9.909122 10.116581 10.174278 10.107040  9.919705  9.882366
364  8.595820  8.716863  8.255569  6.403574  8.098035  8.272826  8.651199
365  8.659907  9.197458  8.854379  8.984443  9.394244  8.779250  9.262838
366  8.764522  8.308692  7.824046  8.309677  8.319230  8.473450  7.795235
372 10.015655  9.945637 10.011445  9.890807  9.956744 10.046072  9.980587
375  8.155936  7.925880  8.398635  8.489205  8.325791  9.596011  8.870803
380 10.244592 10.241673 10.301391 10.241851 10.258641 10.340225 10.167120
381 10.206292 10.127231  9.975296 10.322823 10.299912 10.142504 10.007532
382 10.234229 10.258676 10.239388 10.311117 10.347340 10.395008 10.339029
384  9.134107  9.011402  9.177611  9.130864  9.108197  9.253879  8.830543
387  9.849665  9.983592  9.978781  9.908923 10.099383 10.283635  9.936148
388  8.655040  9.141097  9.222170  8.970813  9.275379  8.978030  9.279773
391  9.235131  9.258654  9.411974  9.279120  9.401704  9.658546  9.551231
392 10.445259 10.480719 10.442230 10.423887 10.531830 10.529720 10.521857
394  9.264734  9.279960  9.117018  9.245611  9.262933  9.261889  9.270588
395 10.538714 10.472290 10.567360 10.630940 10.561784 10.517213 10.553623
396 10.527928 10.620669 10.581140 10.603039 10.604900 10.524064 10.592627
401  9.990445  9.984099  9.738495 10.051606  9.907380 10.047415  9.959632
403 10.646496 10.668955 10.604404 10.613885 10.636192  7.539559 10.668001
409  9.412955  9.364434  9.070043  9.363319  9.137770 10.688758  8.381373
410 10.134758  9.944725 10.125190 10.158324 10.086725 10.259272 10.101108
411  9.340228  9.458294  9.333089  9.333266  9.488502  9.161255  9.258178
413 10.585220 10.679596 10.417239 10.601672 10.588300 10.603635 10.485228
416  8.562167  8.466531  8.037543  7.799343  8.882669 10.545394  5.789960
420 10.418733 10.485368 10.360121 10.458234 10.331855 10.286571 10.338123
422  9.500544  9.549096  9.158310  9.788133  9.476314  9.303740  9.307830
425  8.877661  8.894259  7.969012  8.499436  8.593599  8.921858  7.534228
426  8.735364  8.813141  8.893573  8.718009  9.131946  9.127719  9.153029
430  9.091895  8.870523  8.894944  9.283498  8.979920  8.893023  9.078522
431 10.383534 10.385049 10.440595 10.446219 10.412411 10.598333 10.464845
437 10.013283  9.778094  9.776960  9.893942 10.108223 10.142898  9.800236
439 10.335952 10.262455 10.228791 10.302129 10.312646 10.355136 10.268339
444  8.903951  8.582419  9.115920  8.232706  9.505023  8.006368  7.643483
445 10.300315 10.319497 10.157509 10.251924 10.103649 10.012342  9.962228
446 10.027385 10.025263 10.020915  9.999797  9.917095 10.202258  9.971053
447 10.608168 10.573443 10.603859 10.631761 10.681688  7.278629 10.676347
450  9.849137  9.868534  9.647950  9.968104  9.881344  9.904937  9.900533
451  9.623112  9.488048  9.227886  9.582662  9.455871  9.995428  9.556621
453  9.671934  9.686326  9.912497  9.635673  9.844958  9.839589  9.704366
456  9.791102  9.959821  9.894245  9.733055  9.914576 10.074200  9.819508
457 10.145296 10.054576 10.381707 10.189080 10.210310 10.407530 10.196269
460 10.407258 10.250900 10.311682 10.172522 10.450973 10.462389 10.157277
462 10.572265 10.508295 10.583296 10.562095 10.565428 10.603461 10.527499
463  7.462215  7.647309  8.437284  7.934872  7.835975  9.179675  9.137555
465 10.586685 10.576253 10.515614 10.518268 10.536938 10.602840 10.503834
466 10.237349 10.087849 10.232252 10.313376 10.312646 10.147022 10.148119
468  9.781037  9.671555 10.094728  9.844693  9.785942  9.720946  9.976087
469  7.694393 10.595184 10.614082  7.348588  7.400010 10.639982 10.683729
473 10.654739  7.784057 10.658271 10.670953 10.667419 10.569520 10.619448
474  9.636914  9.610726  9.858229  9.625096  9.723882  9.687382  9.637176
475  8.892199  9.533221  8.858226  7.654443  9.633383  9.777357  9.531191
478 10.138836 10.099137 10.279661 10.106959 10.235342  9.624963 10.150426
479 10.122101 10.146943 10.145335 10.142426 10.150348 10.133050 10.146395
482  8.633375  8.882669  8.405815  8.106515  8.871926  8.906664  8.962648
484 10.015878 10.089801 10.064330  9.953087 10.137254 10.448686 10.281067
486 10.159950 10.453399 10.089469 10.242777 10.192157 10.329180 10.295394
489  9.437635  9.743964  9.559306  9.752374  9.616139  9.544811  9.792333
492  9.908724  9.949416 10.080755  9.775938  9.994379  9.665230  9.702839
499 10.100369 10.247822 10.388103 10.055178 10.119929  9.973760 10.317351
500  7.998671  7.603898  6.507278  8.547334  8.333511 10.637273 10.673341
      G2.T6.4   G2.T3.4   G2.T4.4   G2.T5.4
2   10.494131 10.470391 10.492079 10.451725
4   10.291162 10.323743 10.322560 10.274327
6   10.590893 10.595234 10.582967 10.590793
7   10.422847 10.480775 10.444328 10.334425
8    9.849137  9.944965  9.790935  9.924662
12   8.607582  8.875287  8.495970  8.160232
19   7.234898  8.668540  8.929303  8.806873
21  10.113627 10.246510 10.384369 10.324564
22   9.673886  9.745546  9.833441  9.804275
23  10.493910 10.486485 10.460185 10.470079
26   9.817276  9.676148  9.739438  9.760079
30  10.381831 10.569186 10.302062 10.384586
33  10.523203 10.589560 10.582663 10.493439
36  10.412081 10.657236 10.675862 10.684554
37   9.221379  9.018211  9.241548  9.179572
39   8.545975  9.067624  8.974618  9.022805
41   8.938138  8.651374  8.605753  8.935772
44   9.604879  9.639392  9.862405  9.665801
45   9.923486  9.945685 10.056595 10.017798
50  10.491552 10.566768 10.364387 10.542970
51  10.152455 10.480129 10.437991 10.500564
52   9.855085  9.963406 10.033507  9.965241
56   8.737292  9.149847  8.619750  8.959440
58  10.139863 10.248813  9.916601 10.020070
59   9.668904 10.179262  9.595399  9.477386
62   9.163982  9.257415  8.833900  8.715388
63  10.058952 10.085267  9.850298  9.961096
64  10.425639 10.212992 10.272980 10.358378
68  10.031661 10.381490 10.392650 10.217020
73   6.505784  7.638198  6.386879  7.661998
74  10.523096 10.554875 10.371270 10.379691
76   9.793338 10.107937 10.064883 10.058652
82   9.553504 10.082428  9.878272 10.096172
84   6.834109  7.130099  6.198479  7.734121
87   9.307921  9.757247  9.578934  9.494617
89  10.342130 10.570958  7.551712 10.664504
96  10.112776 10.024022 10.045031 10.221832
103 10.418315 10.480073 10.401501 10.405686
107 10.254813 10.162423 10.262699 10.117671
108  9.682404  9.824444  9.479527  9.543880
113 10.590365 10.577146 10.561629 10.449120
116  9.823578  9.882264 10.048064  9.992322
117  8.720134  9.462732  9.099297  9.599676
119  8.394800  8.649974  7.807510  8.495765
120  8.487352  8.491055  7.721792  7.980024
123  8.251664  6.712956 10.686635  6.955593
130 10.474834 10.548626 10.495626 10.433645
133  8.709630  8.950273  8.596928  8.750366
134  9.322418  9.076123  9.407633  9.514880
139 10.465899 10.427802 10.363125 10.367442
141  9.589462  9.320897  9.518266  9.928473
142  8.868132  8.805675  8.591001  8.889997
144  9.875859  9.617803  9.924564  9.729729
154  9.901586  9.962935 10.135512  9.915317
157  9.044522  9.344784  9.291367  9.608982
158  8.663196  9.355825  5.940171  8.260751
161 10.066626 10.586534 10.572188 10.408858
165  9.628327  9.548882  9.273033  9.384966
168 10.059465 10.310452 10.352587 10.295834
170 10.342420 10.526320 10.579209 10.577121
174 10.112532 10.188140 10.200179 10.315299
176 10.251782 10.342033 10.289124 10.301122
178  8.622094  8.556029  8.727130  8.933137
182  9.254262  9.306559  9.439307  9.378648
183  9.594582  9.675583  9.713477  9.562897
184 10.471808 10.489940 10.534254 10.506382
185  8.986572  9.768069  9.092907  9.319553
187  9.229849  9.809122  9.619333  9.861571
189  9.810604  9.699166  9.371864  9.574914
190 10.167005 10.223576 10.224665 10.262350
191  9.881191 10.001159  9.836493  9.792612
196 10.179793 10.337961 10.178882 10.255024
200  8.148156  8.879612  9.132163  9.027379
202  8.007034  8.343792  8.210940  6.315358
205 10.439659 10.537124 10.578980 10.518538
207  8.674710  9.537411  9.377464  9.236982
208  9.597438  9.292565  9.454541  9.420196
211 10.155219 10.347243 10.219684 10.184334
216  9.982437  9.838095  9.880526  9.987415
219 10.453544 10.295023 10.368447 10.369703
222 10.230342 10.495875 10.471723 10.546604
223 10.401046 10.512030 10.451580 10.469341
224 10.188290 10.454409 10.368981 10.405020
226 10.444707 10.649085 10.322658 10.466640
229  9.376617  9.068085  9.222170  9.364605
233  9.941169 10.418883 10.337994 10.519106
234 10.151285 10.006586 10.006766 10.065394
236  9.224440  9.310909  8.648748  9.093357
245  8.472196  8.334231  8.475746  8.755422
248  9.984145 10.410305 10.289974 10.163888
250  9.292473  9.406483  9.399389  9.467460
251 10.610661  8.056744  7.240650  8.057377
253 10.293365 10.319101 10.411178 10.397482
256  9.326967  9.524859  9.430760  9.409109
257 10.343032 10.415892 10.394121 10.436642
261 10.441500 10.530869 10.627649 10.609921
262  8.479491  9.151015  8.457443  8.461892
269 10.522531 10.525595 10.421537 10.389611
270 10.461359 10.330453 10.370518 10.315829
272 10.055436 10.099712  9.980310  9.886240
274  8.691986  9.350276  8.921324  9.160730
277 10.570111 10.604156 10.493965 10.445637
279 10.286093 10.294685 10.352363 10.370267
280  9.181323  9.812359  9.615005  9.691840
282  9.522813  9.613937  9.711237  9.557611
285 10.000886  9.942804 10.066881 10.015655
288 10.581546 10.639694 10.498719 10.440273
289 10.151129 10.112208 10.266184 10.183692
295 10.654385  7.775276  7.955776  8.072779
306  9.459619  9.814820  9.482198  9.573176
308  9.849348  9.679844  9.859588 10.015521
310  9.024974  9.530756  9.023890  9.084324
311 10.281684 10.166083 10.259727 10.194215
315 10.176602 10.056080  9.979059 10.090962
317 10.205405 10.273256 10.259762 10.321441
320  4.969813  6.866933 10.620888  6.779922
325  9.336973  9.557541  9.561631  9.695910
326 10.475963 10.532230 10.637081 10.445579
331 10.466127 10.440945 10.533269 10.492634
332 10.215045 10.314968  9.856972 10.020559
335 10.033770 10.286230 10.187086 10.305179
336  8.855236  8.737773  8.414274  9.288967
339 10.232144 10.417837 10.061644  9.909967
343  9.973853 10.105326 10.238924 10.168234
348  8.496990  9.251194  9.249946  9.207135
353  9.607168  9.486152  9.721006  9.526610
354  9.666308  9.606226  9.646529  9.588297
355 10.580836  6.261492  7.908387  8.303505
358 10.320717 10.434351 10.389057 10.392589
363 10.286503  9.945924  9.563670  9.599134
364  9.165448  8.712595  9.181220  9.422949
365  8.674026  9.306378  9.224440  8.912473
366  7.922624  8.352083  7.718241  8.810161
372 10.143685 10.237564  9.982068 10.091833
375  7.363280  9.303466  9.103979  9.367259
380 10.310285 10.320881 10.342323 10.315100
381 10.053372 10.096213  9.707351  9.908475
382 10.171145 10.312945 10.305814 10.352523
384  9.309733  9.135617  8.619569  9.267571
387 10.140416 10.380901 10.231027 10.267436
388  9.206132  9.179572  9.508591  9.219895
391  9.542876  9.660141  9.572480  9.699718
392 10.493023 10.513606 10.423976 10.481757
394  8.906529  9.110741  9.135832  9.208939
395 10.607228 10.534094 10.477908 10.366215
396 10.430551 10.592551 10.511213 10.573545
401 10.116985 10.281718  9.972454 10.075422
403  8.248791  7.794823  8.193677  8.456594
409  8.697847  7.502738  8.062118  7.310550
410 10.049923  9.950800  9.819671  9.961379
411  9.219201  9.336092  9.201501  9.251098
413  8.560253  8.393895 10.595058 10.539482
416 10.233654 10.648919 10.583271 10.605941
420 10.424808 10.333060 10.284865 10.328527
422  9.418411  9.253783  9.363748  9.415320
425  8.880307  8.804925  8.846209  8.390723
426  8.453614  8.970559  9.270400  9.053920
430  9.074521  9.319822  8.947546  8.937875
431 10.478330 10.450076 10.413193 10.462131
437 10.281821 10.417059 10.017664 10.192906
439 10.335952 10.447467 10.273291 10.217057
444  2.833213  5.991465  8.383433  8.355145
445 10.279695 10.197462 10.097120 10.153624
446 10.075633 10.185730 10.238566 10.236095
447 10.583955 10.686887 10.671789  6.133398
450  9.778094  9.722984  9.898676  9.690604
451 10.157703 10.272358  9.810495  9.894901
453  9.610324  9.661925  9.825796  9.792444
456  9.803667  9.969931  9.952801  9.868637
457 10.101149 10.300484 10.352044 10.292552
460 10.497891 10.639862 10.437375 10.458923
462 10.556698 10.639071 10.598034 10.491802
463  8.927712  8.862342  8.371242  9.018332
465 10.493771 10.460013 10.597459 10.598233
466 10.341291 10.267262 10.015342 10.143803
468  9.914872  9.775313  9.786841  9.644004
469 10.623301 10.604107 10.644281 10.617784
473  9.243098 10.631640  7.362645  7.293698
474  9.601571  9.465757  9.756031  9.776222
475  9.808902 10.061687  9.736902 10.007622
478  8.786609  9.448097  9.696402  9.270023
479 10.105081 10.054576 10.149644 10.057838
482  9.438670  9.302464  9.005037  9.056023
484 10.273429 10.566588 10.455446 10.486541
486 10.194178 10.353416 10.374335 10.269033
489  9.819725  9.722205  9.762673  9.984560
492  9.716194  9.960482  9.952611  9.975948
499  9.756379  9.879656 10.018511 10.106102
500 10.588451 10.679895 10.631592 10.684188

$coefficients
       beta0 betaGroup.2vsGroup.1      betaTime betaTimexGroup.2
2   2.341797          0.011750690  0.0000000000     0.0000000000
4   2.332467          0.000000000  0.0000000000     0.0046917019
6   2.354382          0.005613270  0.0000000000     0.0000000000
7   2.334190          0.011129147  0.0000000000     0.0000000000
8   2.287567         -0.028593809  0.0000000000     0.0000000000
12  2.152415          0.000000000  0.0000000000    -0.0231538295
19  2.082925          0.087123015  0.0000000000     0.0000000000
21  2.346575         -0.021644881  0.0000000000     0.0000000000
22  2.292050         -0.012209275  0.0000000000     0.0000000000
23  2.341994          0.002328997  0.0000000000     0.0000000000
26  2.275207          0.000000000 -0.0005789362     0.0031507273
30  2.350058         -0.012629086  0.0000000000    -0.0040501404
33  2.360549         -0.005107140 -0.0009458816     0.0000000000
36  2.264498          0.000000000 -0.0211867584     0.0312078580
37  2.246447         -0.014813639  0.0000000000     0.0000000000
39  2.232927         -0.113156040  0.0000000000     0.0000000000
41  2.151252          0.000000000  0.0000000000    -0.0148113327
44  2.271304          0.000000000  0.0000000000     0.0061540766
45  2.296075          0.013847427  0.0000000000     0.0000000000
50  2.341407          0.011567286  0.0000000000     0.0000000000
51  2.334542          0.010643798  0.0013522096     0.0000000000
52  2.308094          0.000000000 -0.0010970536     0.0016505816
56  2.209585          0.000000000  0.0000000000    -0.0224082675
58  2.326190         -0.029542636  0.0000000000     0.0000000000
59  2.277320         -0.138315542  0.0000000000     0.0059297814
62  2.186381          0.012307776  0.0000000000     0.0038190082
63  2.313579         -0.012334452 -0.0014925189     0.0000000000
64  2.323676          0.010209452  0.0000000000     0.0000000000
68  2.333390          0.000000000  0.0000000000    -0.0178826216
73  2.090393          0.000000000  0.0000000000     0.0522641365
74  2.349621         -0.037451768  0.0000000000    -0.0062670478
76  2.294314          0.016273755  0.0000000000     0.0000000000
82  2.318003         -0.016430506  0.0000000000     0.0000000000
84  2.343423         -0.165262590  0.0000000000    -0.0088595497
87  2.212554          0.034977293  0.0000000000    -0.0077243000
89  2.362981         -0.180332802  0.0000000000     0.0265795943
96  2.333786         -0.023338963  0.0000000000     0.0000000000
103 2.333720          0.007207928  0.0000000000     0.0000000000
107 2.312102          0.010772104  0.0000000000     0.0000000000
108 2.286286         -0.083866382  0.0000000000     0.0000000000
113 2.354537          0.005843290  0.0000000000     0.0000000000
116 2.280021          0.014233830  0.0000000000     0.0000000000
117 2.169646          0.064153431  0.0000000000     0.0000000000
119 2.270752         -0.165717124  0.0000000000     0.0000000000
120 1.953338          0.179477027  0.0276676139    -0.0329626816
123 2.045883          0.147047199  0.0000000000     0.0393903525
130 2.344627          0.000000000  0.0000000000    -0.0247414411
133 2.226385         -0.045918625  0.0000000000     0.0000000000
134 2.202467          0.022987976  0.0000000000     0.0000000000
139 2.334161          0.009981288  0.0010935052     0.0000000000
141 2.280362         -0.031092250  0.0000000000     0.0000000000
142 2.197306         -0.030192504  0.0000000000     0.0017882912
144 2.295074         -0.018512390  0.0000000000     0.0000000000
154 2.309882          0.006552088  0.0000000000     0.0000000000
157 2.270814         -0.026363809  0.0000000000     0.0000000000
158 2.157219          0.130794738  0.0000000000     0.0000000000
161 2.357084         -0.128514726  0.0000000000     0.0000000000
165 2.253720          0.000000000  0.0000000000    -0.0074640924
168 2.337026         -0.010421663  0.0000000000    -0.0027596151
170 2.359842         -0.012912444  0.0000000000     0.0000000000
174 2.335689          0.000000000  0.0000000000    -0.0038111051
176 2.316931          0.013182176  0.0012195785     0.0000000000
178 2.124669          0.034729153  0.0000000000     0.0000000000
182 2.272956          0.000000000  0.0000000000     0.0102919425
183 2.273154         -0.022703996  0.0000000000     0.0000000000
184 2.359311         -0.007517487  0.0000000000    -0.0012619628
185 2.253177         -0.022898292  0.0000000000    -0.0092160931
187 2.253592          0.021440520  0.0000000000     0.0000000000
189 2.260960         -0.023814349 -0.0008381947     0.0000000000
190 2.304317          0.014419578  0.0000000000     0.0000000000
191 2.272683          0.000000000  0.0000000000     0.0062119394
196 2.328652          0.000000000  0.0000000000    -0.0051532601
200 2.209210          0.000000000  0.0000000000    -0.0185225738
202 1.983244          0.166785815  0.0000000000     0.0000000000
205 2.358616          0.000000000  0.0000000000     0.0003540681
207 2.221818         -0.032363882  0.0000000000    -0.0072912817
208 2.214148          0.028938981  0.0000000000     0.0000000000
211 2.345218         -0.041229030  0.0000000000    -0.0078739857
216 2.301980         -0.011224160  0.0000000000    -0.0024229234
219 2.343173          0.000000000  0.0000000000     0.0000000000
222 2.355751         -0.036291728  0.0000000000     0.0000000000
223 2.350830          0.000000000  0.0000000000    -0.0012927702
224 2.329993          0.011747364  0.0000000000     0.0000000000
226 2.353969         -0.042507176  0.0000000000    -0.0115868969
229 2.242512         -0.019548572  0.0000000000     0.0000000000
233 2.314865          0.025399060  0.0000000000     0.0000000000
234 2.305168          0.014469619  0.0000000000     0.0000000000
236 2.224810         -0.065276692  0.0000000000     0.0000000000
245 2.100221          0.035637355  0.0067433034     0.0000000000
248 2.294723          0.027782150  0.0000000000     0.0000000000
250 2.243618          0.000000000  0.0004304363    -0.0035057794
251 2.063248          0.128215222  0.0000000000     0.0349470323
253 2.338827          0.009309953  0.0000000000     0.0000000000
256 2.260718         -0.022555180 -0.0038197635     0.0000000000
257 2.334006          0.010465883  0.0000000000     0.0000000000
261 2.345112          0.009970786  0.0000000000     0.0000000000
262 2.188218         -0.061229316  0.0000000000     0.0000000000
269 2.352784         -0.009122034  0.0000000000    -0.0024693255
270 2.291363          0.046151040  0.0000000000     0.0000000000
272 2.321696         -0.031278256 -0.0029684409     0.0000000000
274 2.249382         -0.026900851  0.0000000000    -0.0079242118
277 2.358536         -0.023014737  0.0000000000    -0.0048934032
279 2.336752          0.003897589  0.0007188859    -0.0003456938
280 2.283843         -0.022613854  0.0000000000     0.0000000000
282 2.249993          0.013385947  0.0000000000     0.0000000000
285 2.325466         -0.009363096  0.0000000000     0.0000000000
288 2.350660         -0.007567899  0.0000000000    -0.0015356915
289 2.311961          0.009157599  0.0000000000     0.0000000000
295 2.186184          0.000000000  0.0000000000     0.0293902909
306 2.280185         -0.022854605  0.0000000000     0.0000000000
308 2.306463         -0.055324931  0.0000000000     0.0000000000
310 2.251758         -0.040628562  0.0000000000     0.0000000000
311 2.308492          0.012352269  0.0000000000     0.0000000000
315 2.326340         -0.028481567  0.0000000000    -0.0028116485
317 2.341120         -0.012078424  0.0000000000     0.0000000000
320 2.308825          0.069754104  0.0000000000     0.0000000000
325 2.218961          0.055918404  0.0000000000     0.0000000000
326 2.347528          0.006054763  0.0000000000     0.0000000000
331 2.347745          0.008004978  0.0000000000     0.0000000000
332 2.307834         -0.032318594  0.0000000000    -0.0069981641
335 2.319006          0.010557165  0.0000000000     0.0000000000
336 2.179584         -0.051641336  0.0000000000     0.0036038335
339 2.326314         -0.046235785  0.0000000000    -0.0118713404
343 2.310425          0.010240167  0.0000000000     0.0000000000
348 2.143837          0.078183897  0.0000000000     0.0000000000
353 2.281627         -0.021403393  0.0000000000     0.0024278621
354 2.285146         -0.020002908  0.0000000000     0.0000000000
355 2.278542         -0.092855434  0.0000000000     0.0312858591
358 2.331333          0.009163568  0.0009329413    -0.0011293807
363 2.276860          0.018696177  0.0024376948     0.0000000000
364 2.189438          0.000000000  0.0000000000    -0.0232299350
365 2.196199         -0.029849504  0.0062592089     0.0000000000
366 1.924917          0.211195065  0.0294581483    -0.0323578375
372 2.326954         -0.019414294  0.0000000000    -0.0018081588
375 2.269311         -0.064954450  0.0000000000    -0.0146572789
380 2.335816          0.000000000  0.0000000000    -0.0016915269
381 2.323867         -0.021599850  0.0000000000     0.0039768596
382 2.319059          0.013719900  0.0000000000     0.0000000000
384 2.160498          0.045420541  0.0000000000     0.0000000000
387 2.338587         -0.029475241  0.0000000000    -0.0025096602
388 2.144704          0.049935413  0.0000000000     0.0014327660
391 2.286112         -0.023144178  0.0000000000    -0.0060388837
392 2.346141          0.000000000 -0.0002453748     0.0004301386
394 2.216865          0.000000000  0.0000000000     0.0027909905
395 2.343709          0.007957669  0.0010131256     0.0000000000
396 2.351769          0.005932297  0.0000000000     0.0000000000
401 2.320168         -0.015039250  0.0000000000    -0.0022897832
403 2.083993          0.000000000  0.0000000000     0.0450617501
409 2.152951          0.071068080  0.0000000000     0.0000000000
410 2.309332         -0.017878882 -0.0023155039     0.0060667444
411 2.218386          0.013861312  0.0000000000     0.0000000000
413 2.064798          0.250789400  0.0000000000     0.0000000000
416 2.337546          0.000000000  0.0000000000    -0.0443956506
420 2.327992          0.000000000  0.0000000000     0.0023884080
422 2.263630         -0.012580078  0.0000000000     0.0000000000
425 2.051340          0.087839168  0.0000000000     0.0000000000
426 2.128585          0.061483178  0.0000000000     0.0000000000
430 2.230984         -0.030299530  0.0000000000     0.0000000000
431 2.341641          0.005077064  0.0000000000     0.0000000000
437 2.349603         -0.037265195  0.0000000000    -0.0050679026
439 2.340392          0.000000000  0.0000000000    -0.0020028289
444 2.155144          0.000000000  0.0000000000     0.0000000000
445 2.337985         -0.018670094  0.0000000000     0.0000000000
446 2.339789         -0.023881882  0.0000000000    -0.0038272362
447 2.181593          0.000000000 -0.0380346157     0.0690790729
450 2.271576          0.022032544  0.0000000000    -0.0005805427
451 2.317240         -0.039480654  0.0000000000    -0.0069128920
453 2.268717          0.010801688  0.0000000000     0.0000000000
456 2.279652          0.012573284  0.0000000000     0.0000000000
457 2.344675         -0.017896682  0.0000000000     0.0000000000
460 2.353648         -0.010177709  0.0000000000    -0.0026338650
462 2.223906          0.135249037  0.0000000000     0.0000000000
463 2.187831          0.000000000  0.0000000000    -0.0196353575
465 2.360128          0.000000000  0.0000000000    -0.0008032942
466 2.310127          0.000000000  0.0000000000     0.0028593370
468 2.278733          0.012244966  0.0000000000     0.0000000000
469 2.142320          0.000000000  0.0000000000     0.0000000000
473 1.880993          0.176412482  0.0448820221     0.0000000000
474 2.253586          0.016553000  0.0000000000     0.0000000000
475 2.315156         -0.061580539  0.0000000000    -0.0093913369
478 2.275867          0.000000000  0.0000000000     0.0074848361
479 2.307311          0.007819362  0.0000000000     0.0000000000
482 2.199715          0.000000000  0.0000000000    -0.0088888776
484 2.354517         -0.033707431  0.0000000000    -0.0037508832
486 2.341618         -0.014936676  0.0000000000     0.0000000000
489 2.238589          0.019191867  0.0000000000     0.0011781690
492 2.262202          0.027244192  0.0000000000     0.0000000000
499 2.322810         -0.027999353  0.0000000000     0.0048814111
500 2.036715          0.121527990  0.0000000000     0.0000000000
        betaTime2 betaTime2xGroup.2
2    0.000000e+00      0.000000e+00
4    0.000000e+00     -1.970172e-04
6    0.000000e+00      0.000000e+00
7    0.000000e+00      0.000000e+00
8    0.000000e+00      5.367678e-05
12   0.000000e+00      9.493862e-04
19   0.000000e+00      0.000000e+00
21   0.000000e+00      0.000000e+00
22   0.000000e+00      0.000000e+00
23   0.000000e+00      8.397853e-06
26   0.000000e+00     -1.042639e-04
30   0.000000e+00      1.792519e-04
33   3.937433e-05      0.000000e+00
36   7.925991e-04     -1.051870e-03
37   0.000000e+00     -2.715811e-05
39   0.000000e+00      1.218835e-04
41   0.000000e+00      6.560827e-04
44   0.000000e+00     -2.571824e-04
45   0.000000e+00     -1.445836e-05
50   0.000000e+00      0.000000e+00
51  -5.988209e-05      0.000000e+00
52   4.007264e-05     -8.021481e-05
56   0.000000e+00      8.932260e-04
58   0.000000e+00      2.479175e-05
59   0.000000e+00      0.000000e+00
62   0.000000e+00     -1.631511e-04
63   5.997232e-05      0.000000e+00
64   0.000000e+00      0.000000e+00
68   0.000000e+00      7.436907e-04
73   0.000000e+00     -2.426935e-03
74   0.000000e+00      3.257955e-04
76   0.000000e+00      0.000000e+00
82   0.000000e+00      0.000000e+00
84   0.000000e+00      0.000000e+00
87   0.000000e+00      3.362039e-04
89   0.000000e+00     -9.411468e-04
96   0.000000e+00      0.000000e+00
103  0.000000e+00      0.000000e+00
107  0.000000e+00      0.000000e+00
108  0.000000e+00      1.134680e-04
113  0.000000e+00     -8.322032e-06
116  0.000000e+00      0.000000e+00
117  0.000000e+00      0.000000e+00
119  0.000000e+00      0.000000e+00
120 -1.161480e-03      1.330568e-03
123  0.000000e+00     -1.812591e-03
130  0.000000e+00      1.049909e-03
133  0.000000e+00      0.000000e+00
134  0.000000e+00      0.000000e+00
139 -5.006238e-05      0.000000e+00
141  0.000000e+00      0.000000e+00
142 -6.049560e-05      0.000000e+00
144  0.000000e+00      0.000000e+00
154  0.000000e+00     -2.719499e-05
157  0.000000e+00      0.000000e+00
158  0.000000e+00     -3.500778e-04
161  0.000000e+00      2.033288e-04
165  0.000000e+00      3.006408e-04
168  0.000000e+00      1.186102e-04
170  0.000000e+00      0.000000e+00
174  0.000000e+00      1.372342e-04
176 -4.937892e-05      0.000000e+00
178  0.000000e+00      0.000000e+00
182  0.000000e+00     -5.006441e-04
183  0.000000e+00      0.000000e+00
184  0.000000e+00      5.268376e-05
185  0.000000e+00      3.834150e-04
187  0.000000e+00      0.000000e+00
189  0.000000e+00      8.063386e-05
190  0.000000e+00      0.000000e+00
191 -4.117197e-05     -1.885871e-04
196  0.000000e+00      2.113129e-04
200  0.000000e+00      7.181383e-04
202  2.366610e-04     -4.222854e-04
205 -2.141963e-05      0.000000e+00
207  0.000000e+00      3.616112e-04
208  0.000000e+00      0.000000e+00
211  0.000000e+00      3.679593e-04
216  0.000000e+00      1.094675e-04
219 -1.432146e-04      1.377524e-04
222  0.000000e+00      4.717885e-05
223  0.000000e+00      4.804638e-05
224  0.000000e+00      0.000000e+00
226  0.000000e+00      5.524054e-04
229  0.000000e+00      0.000000e+00
233  0.000000e+00      0.000000e+00
234  0.000000e+00     -2.008486e-05
236  0.000000e+00      7.909217e-05
245 -2.563790e-04      0.000000e+00
248  0.000000e+00      0.000000e+00
250  0.000000e+00      1.228751e-04
251  0.000000e+00     -1.563112e-03
253  0.000000e+00     -1.838741e-05
256  1.515585e-04      0.000000e+00
257  0.000000e+00      0.000000e+00
261  0.000000e+00      0.000000e+00
262 -7.722219e-05      1.237971e-04
269  0.000000e+00      1.115007e-04
270  0.000000e+00      0.000000e+00
272  1.358671e-04      0.000000e+00
274  0.000000e+00      2.928949e-04
277  0.000000e+00      2.397889e-04
279 -2.642898e-05      0.000000e+00
280  0.000000e+00      0.000000e+00
282  0.000000e+00      0.000000e+00
285  0.000000e+00     -2.247618e-05
288  0.000000e+00      8.592092e-05
289  0.000000e+00      0.000000e+00
295  0.000000e+00     -1.293603e-03
306  0.000000e+00      0.000000e+00
308  0.000000e+00      6.393607e-05
310  0.000000e+00      0.000000e+00
311  0.000000e+00      0.000000e+00
315  0.000000e+00      1.398847e-04
317  0.000000e+00      0.000000e+00
320  0.000000e+00     -6.651760e-04
325  0.000000e+00     -3.295698e-05
326  0.000000e+00      0.000000e+00
331  0.000000e+00     -9.905252e-06
332  0.000000e+00      3.594817e-04
335  0.000000e+00      0.000000e+00
336 -6.207429e-05      0.000000e+00
339  0.000000e+00      5.660818e-04
343  0.000000e+00      0.000000e+00
348  0.000000e+00      0.000000e+00
353  0.000000e+00     -1.006109e-04
354  0.000000e+00      0.000000e+00
355  0.000000e+00     -1.444874e-03
358 -3.892141e-05      4.707807e-05
363 -1.141111e-04      0.000000e+00
364  0.000000e+00      1.004480e-03
365 -2.747353e-04      7.272862e-05
366 -1.045527e-03      1.109280e-03
372  0.000000e+00      8.670415e-05
375  0.000000e+00      5.645483e-04
380  0.000000e+00      6.805057e-05
381  0.000000e+00     -1.759208e-04
382  0.000000e+00      0.000000e+00
384  0.000000e+00      0.000000e+00
387  0.000000e+00      1.385304e-04
388  0.000000e+00      0.000000e+00
391  0.000000e+00      2.556517e-04
392  0.000000e+00      0.000000e+00
394  1.948064e-05     -1.536950e-04
395 -4.470383e-05      0.000000e+00
396 -8.864988e-06      0.000000e+00
401  0.000000e+00      1.115521e-04
403  0.000000e+00     -1.851858e-03
409  0.000000e+00     -2.636813e-04
410  9.727426e-05     -2.429550e-04
411  0.000000e+00      0.000000e+00
413  0.000000e+00      0.000000e+00
416  0.000000e+00      1.879161e-03
420  0.000000e+00     -8.570545e-05
422  0.000000e+00     -2.461198e-05
425  0.000000e+00      0.000000e+00
426  0.000000e+00      0.000000e+00
430  0.000000e+00      0.000000e+00
431  0.000000e+00      0.000000e+00
437  0.000000e+00      2.356723e-04
439  0.000000e+00      7.290180e-05
444  0.000000e+00     -5.169979e-04
445  0.000000e+00      0.000000e+00
446  0.000000e+00      1.699345e-04
447  1.296337e-03     -2.477959e-03
450  0.000000e+00      0.000000e+00
451  0.000000e+00      3.409855e-04
453  0.000000e+00      0.000000e+00
456  0.000000e+00      0.000000e+00
457  0.000000e+00      0.000000e+00
460  0.000000e+00      1.256131e-04
462 -4.626449e-04      4.601752e-04
463  0.000000e+00      8.011289e-04
465  0.000000e+00      2.458399e-05
466  0.000000e+00     -9.989073e-05
468 -2.295673e-05      0.000000e+00
469 -5.185628e-04      9.067114e-04
473 -1.602480e-03      0.000000e+00
474  0.000000e+00      0.000000e+00
475  0.000000e+00      4.604580e-04
478  0.000000e+00     -3.922510e-04
479  0.000000e+00      0.000000e+00
482  0.000000e+00      4.058195e-04
484  0.000000e+00      2.038019e-04
486  0.000000e+00      0.000000e+00
489  0.000000e+00      0.000000e+00
492  0.000000e+00      0.000000e+00
499  0.000000e+00     -2.009119e-04
500  3.696960e-04      0.000000e+00

$group.coeffs
    Group.1_beta0 Group.1_beta1 Group.1_beta2 Group.2_beta0 Group.2_beta1
2        2.341797  0.0000000000  0.000000e+00      2.353548  0.0000000000
4        2.332467  0.0000000000  0.000000e+00      2.332467  0.0046917019
6        2.354382  0.0000000000  0.000000e+00      2.359995  0.0000000000
7        2.334190  0.0000000000  0.000000e+00      2.345320  0.0000000000
8        2.287567  0.0000000000  0.000000e+00      2.258974  0.0000000000
12       2.152415  0.0000000000  0.000000e+00      2.152415 -0.0231538295
19       2.082925  0.0000000000  0.000000e+00      2.170048  0.0000000000
21       2.346575  0.0000000000  0.000000e+00      2.324930  0.0000000000
22       2.292050  0.0000000000  0.000000e+00      2.279841  0.0000000000
23       2.341994  0.0000000000  0.000000e+00      2.344323  0.0000000000
26       2.275207 -0.0005789362  0.000000e+00      2.275207  0.0025717911
30       2.350058  0.0000000000  0.000000e+00      2.337429 -0.0040501404
33       2.360549 -0.0009458816  3.937433e-05      2.355442 -0.0009458816
36       2.264498 -0.0211867584  7.925991e-04      2.264498  0.0100210996
37       2.246447  0.0000000000  0.000000e+00      2.231634  0.0000000000
39       2.232927  0.0000000000  0.000000e+00      2.119771  0.0000000000
41       2.151252  0.0000000000  0.000000e+00      2.151252 -0.0148113327
44       2.271304  0.0000000000  0.000000e+00      2.271304  0.0061540766
45       2.296075  0.0000000000  0.000000e+00      2.309922  0.0000000000
50       2.341407  0.0000000000  0.000000e+00      2.352974  0.0000000000
51       2.334542  0.0013522096 -5.988209e-05      2.345186  0.0013522096
52       2.308094 -0.0010970536  4.007264e-05      2.308094  0.0005535280
56       2.209585  0.0000000000  0.000000e+00      2.209585 -0.0224082675
58       2.326190  0.0000000000  0.000000e+00      2.296647  0.0000000000
59       2.277320  0.0000000000  0.000000e+00      2.139005  0.0059297814
62       2.186381  0.0000000000  0.000000e+00      2.198689  0.0038190082
63       2.313579 -0.0014925189  5.997232e-05      2.301245 -0.0014925189
64       2.323676  0.0000000000  0.000000e+00      2.333886  0.0000000000
68       2.333390  0.0000000000  0.000000e+00      2.333390 -0.0178826216
73       2.090393  0.0000000000  0.000000e+00      2.090393  0.0522641365
74       2.349621  0.0000000000  0.000000e+00      2.312169 -0.0062670478
76       2.294314  0.0000000000  0.000000e+00      2.310588  0.0000000000
82       2.318003  0.0000000000  0.000000e+00      2.301573  0.0000000000
84       2.343423  0.0000000000  0.000000e+00      2.178161 -0.0088595497
87       2.212554  0.0000000000  0.000000e+00      2.247531 -0.0077243000
89       2.362981  0.0000000000  0.000000e+00      2.182648  0.0265795943
96       2.333786  0.0000000000  0.000000e+00      2.310447  0.0000000000
103      2.333720  0.0000000000  0.000000e+00      2.340928  0.0000000000
107      2.312102  0.0000000000  0.000000e+00      2.322874  0.0000000000
108      2.286286  0.0000000000  0.000000e+00      2.202420  0.0000000000
113      2.354537  0.0000000000  0.000000e+00      2.360380  0.0000000000
116      2.280021  0.0000000000  0.000000e+00      2.294255  0.0000000000
117      2.169646  0.0000000000  0.000000e+00      2.233800  0.0000000000
119      2.270752  0.0000000000  0.000000e+00      2.105035  0.0000000000
120      1.953338  0.0276676139 -1.161480e-03      2.132815 -0.0052950677
123      2.045883  0.0000000000  0.000000e+00      2.192930  0.0393903525
130      2.344627  0.0000000000  0.000000e+00      2.344627 -0.0247414411
133      2.226385  0.0000000000  0.000000e+00      2.180467  0.0000000000
134      2.202467  0.0000000000  0.000000e+00      2.225455  0.0000000000
139      2.334161  0.0010935052 -5.006238e-05      2.344143  0.0010935052
141      2.280362  0.0000000000  0.000000e+00      2.249270  0.0000000000
142      2.197306  0.0000000000 -6.049560e-05      2.167114  0.0017882912
144      2.295074  0.0000000000  0.000000e+00      2.276562  0.0000000000
154      2.309882  0.0000000000  0.000000e+00      2.316434  0.0000000000
157      2.270814  0.0000000000  0.000000e+00      2.244450  0.0000000000
158      2.157219  0.0000000000  0.000000e+00      2.288014  0.0000000000
161      2.357084  0.0000000000  0.000000e+00      2.228569  0.0000000000
165      2.253720  0.0000000000  0.000000e+00      2.253720 -0.0074640924
168      2.337026  0.0000000000  0.000000e+00      2.326604 -0.0027596151
170      2.359842  0.0000000000  0.000000e+00      2.346930  0.0000000000
174      2.335689  0.0000000000  0.000000e+00      2.335689 -0.0038111051
176      2.316931  0.0012195785 -4.937892e-05      2.330113  0.0012195785
178      2.124669  0.0000000000  0.000000e+00      2.159398  0.0000000000
182      2.272956  0.0000000000  0.000000e+00      2.272956  0.0102919425
183      2.273154  0.0000000000  0.000000e+00      2.250450  0.0000000000
184      2.359311  0.0000000000  0.000000e+00      2.351794 -0.0012619628
185      2.253177  0.0000000000  0.000000e+00      2.230278 -0.0092160931
187      2.253592  0.0000000000  0.000000e+00      2.275032  0.0000000000
189      2.260960 -0.0008381947  0.000000e+00      2.237146 -0.0008381947
190      2.304317  0.0000000000  0.000000e+00      2.318737  0.0000000000
191      2.272683  0.0000000000 -4.117197e-05      2.272683  0.0062119394
196      2.328652  0.0000000000  0.000000e+00      2.328652 -0.0051532601
200      2.209210  0.0000000000  0.000000e+00      2.209210 -0.0185225738
202      1.983244  0.0000000000  2.366610e-04      2.150030  0.0000000000
205      2.358616  0.0000000000 -2.141963e-05      2.358616  0.0003540681
207      2.221818  0.0000000000  0.000000e+00      2.189454 -0.0072912817
208      2.214148  0.0000000000  0.000000e+00      2.243087  0.0000000000
211      2.345218  0.0000000000  0.000000e+00      2.303989 -0.0078739857
216      2.301980  0.0000000000  0.000000e+00      2.290756 -0.0024229234
219      2.343173  0.0000000000 -1.432146e-04      2.343173  0.0000000000
222      2.355751  0.0000000000  0.000000e+00      2.319460  0.0000000000
223      2.350830  0.0000000000  0.000000e+00      2.350830 -0.0012927702
224      2.329993  0.0000000000  0.000000e+00      2.341740  0.0000000000
226      2.353969  0.0000000000  0.000000e+00      2.311462 -0.0115868969
229      2.242512  0.0000000000  0.000000e+00      2.222964  0.0000000000
233      2.314865  0.0000000000  0.000000e+00      2.340264  0.0000000000
234      2.305168  0.0000000000  0.000000e+00      2.319637  0.0000000000
236      2.224810  0.0000000000  0.000000e+00      2.159533  0.0000000000
245      2.100221  0.0067433034 -2.563790e-04      2.135858  0.0067433034
248      2.294723  0.0000000000  0.000000e+00      2.322505  0.0000000000
250      2.243618  0.0004304363  0.000000e+00      2.243618 -0.0030753432
251      2.063248  0.0000000000  0.000000e+00      2.191464  0.0349470323
253      2.338827  0.0000000000  0.000000e+00      2.348137  0.0000000000
256      2.260718 -0.0038197635  1.515585e-04      2.238163 -0.0038197635
257      2.334006  0.0000000000  0.000000e+00      2.344472  0.0000000000
261      2.345112  0.0000000000  0.000000e+00      2.355083  0.0000000000
262      2.188218  0.0000000000 -7.722219e-05      2.126989  0.0000000000
269      2.352784  0.0000000000  0.000000e+00      2.343662 -0.0024693255
270      2.291363  0.0000000000  0.000000e+00      2.337514  0.0000000000
272      2.321696 -0.0029684409  1.358671e-04      2.290417 -0.0029684409
274      2.249382  0.0000000000  0.000000e+00      2.222481 -0.0079242118
277      2.358536  0.0000000000  0.000000e+00      2.335522 -0.0048934032
279      2.336752  0.0007188859 -2.642898e-05      2.340650  0.0003731921
280      2.283843  0.0000000000  0.000000e+00      2.261229  0.0000000000
282      2.249993  0.0000000000  0.000000e+00      2.263379  0.0000000000
285      2.325466  0.0000000000  0.000000e+00      2.316103  0.0000000000
288      2.350660  0.0000000000  0.000000e+00      2.343092 -0.0015356915
289      2.311961  0.0000000000  0.000000e+00      2.321119  0.0000000000
295      2.186184  0.0000000000  0.000000e+00      2.186184  0.0293902909
306      2.280185  0.0000000000  0.000000e+00      2.257330  0.0000000000
308      2.306463  0.0000000000  0.000000e+00      2.251138  0.0000000000
310      2.251758  0.0000000000  0.000000e+00      2.211130  0.0000000000
311      2.308492  0.0000000000  0.000000e+00      2.320844  0.0000000000
315      2.326340  0.0000000000  0.000000e+00      2.297859 -0.0028116485
317      2.341120  0.0000000000  0.000000e+00      2.329042  0.0000000000
320      2.308825  0.0000000000  0.000000e+00      2.378579  0.0000000000
325      2.218961  0.0000000000  0.000000e+00      2.274880  0.0000000000
326      2.347528  0.0000000000  0.000000e+00      2.353582  0.0000000000
331      2.347745  0.0000000000  0.000000e+00      2.355750  0.0000000000
332      2.307834  0.0000000000  0.000000e+00      2.275515 -0.0069981641
335      2.319006  0.0000000000  0.000000e+00      2.329564  0.0000000000
336      2.179584  0.0000000000 -6.207429e-05      2.127942  0.0036038335
339      2.326314  0.0000000000  0.000000e+00      2.280078 -0.0118713404
343      2.310425  0.0000000000  0.000000e+00      2.320665  0.0000000000
348      2.143837  0.0000000000  0.000000e+00      2.222021  0.0000000000
353      2.281627  0.0000000000  0.000000e+00      2.260224  0.0024278621
354      2.285146  0.0000000000  0.000000e+00      2.265143  0.0000000000
355      2.278542  0.0000000000  0.000000e+00      2.185686  0.0312858591
358      2.331333  0.0009329413 -3.892141e-05      2.340497 -0.0001964394
363      2.276860  0.0024376948 -1.141111e-04      2.295556  0.0024376948
364      2.189438  0.0000000000  0.000000e+00      2.189438 -0.0232299350
365      2.196199  0.0062592089 -2.747353e-04      2.166349  0.0062592089
366      1.924917  0.0294581483 -1.045527e-03      2.136112 -0.0028996892
372      2.326954  0.0000000000  0.000000e+00      2.307540 -0.0018081588
375      2.269311  0.0000000000  0.000000e+00      2.204356 -0.0146572789
380      2.335816  0.0000000000  0.000000e+00      2.335816 -0.0016915269
381      2.323867  0.0000000000  0.000000e+00      2.302267  0.0039768596
382      2.319059  0.0000000000  0.000000e+00      2.332779  0.0000000000
384      2.160498  0.0000000000  0.000000e+00      2.205918  0.0000000000
387      2.338587  0.0000000000  0.000000e+00      2.309112 -0.0025096602
388      2.144704  0.0000000000  0.000000e+00      2.194640  0.0014327660
391      2.286112  0.0000000000  0.000000e+00      2.262968 -0.0060388837
392      2.346141 -0.0002453748  0.000000e+00      2.346141  0.0001847639
394      2.216865  0.0000000000  1.948064e-05      2.216865  0.0027909905
395      2.343709  0.0010131256 -4.470383e-05      2.351667  0.0010131256
396      2.351769  0.0000000000 -8.864988e-06      2.357702  0.0000000000
401      2.320168  0.0000000000  0.000000e+00      2.305129 -0.0022897832
403      2.083993  0.0000000000  0.000000e+00      2.083993  0.0450617501
409      2.152951  0.0000000000  0.000000e+00      2.224019  0.0000000000
410      2.309332 -0.0023155039  9.727426e-05      2.291453  0.0037512404
411      2.218386  0.0000000000  0.000000e+00      2.232248  0.0000000000
413      2.064798  0.0000000000  0.000000e+00      2.315587  0.0000000000
416      2.337546  0.0000000000  0.000000e+00      2.337546 -0.0443956506
420      2.327992  0.0000000000  0.000000e+00      2.327992  0.0023884080
422      2.263630  0.0000000000  0.000000e+00      2.251050  0.0000000000
425      2.051340  0.0000000000  0.000000e+00      2.139180  0.0000000000
426      2.128585  0.0000000000  0.000000e+00      2.190068  0.0000000000
430      2.230984  0.0000000000  0.000000e+00      2.200685  0.0000000000
431      2.341641  0.0000000000  0.000000e+00      2.346718  0.0000000000
437      2.349603  0.0000000000  0.000000e+00      2.312338 -0.0050679026
439      2.340392  0.0000000000  0.000000e+00      2.340392 -0.0020028289
444      2.155144  0.0000000000  0.000000e+00      2.155144  0.0000000000
445      2.337985  0.0000000000  0.000000e+00      2.319315  0.0000000000
446      2.339789  0.0000000000  0.000000e+00      2.315907 -0.0038272362
447      2.181593 -0.0380346157  1.296337e-03      2.181593  0.0310444572
450      2.271576  0.0000000000  0.000000e+00      2.293609 -0.0005805427
451      2.317240  0.0000000000  0.000000e+00      2.277760 -0.0069128920
453      2.268717  0.0000000000  0.000000e+00      2.279519  0.0000000000
456      2.279652  0.0000000000  0.000000e+00      2.292226  0.0000000000
457      2.344675  0.0000000000  0.000000e+00      2.326778  0.0000000000
460      2.353648  0.0000000000  0.000000e+00      2.343470 -0.0026338650
462      2.223906  0.0000000000 -4.626449e-04      2.359155  0.0000000000
463      2.187831  0.0000000000  0.000000e+00      2.187831 -0.0196353575
465      2.360128  0.0000000000  0.000000e+00      2.360128 -0.0008032942
466      2.310127  0.0000000000  0.000000e+00      2.310127  0.0028593370
468      2.278733  0.0000000000 -2.295673e-05      2.290978  0.0000000000
469      2.142320  0.0000000000 -5.185628e-04      2.142320  0.0000000000
473      1.880993  0.0448820221 -1.602480e-03      2.057405  0.0448820221
474      2.253586  0.0000000000  0.000000e+00      2.270139  0.0000000000
475      2.315156  0.0000000000  0.000000e+00      2.253575 -0.0093913369
478      2.275867  0.0000000000  0.000000e+00      2.275867  0.0074848361
479      2.307311  0.0000000000  0.000000e+00      2.315131  0.0000000000
482      2.199715  0.0000000000  0.000000e+00      2.199715 -0.0088888776
484      2.354517  0.0000000000  0.000000e+00      2.320810 -0.0037508832
486      2.341618  0.0000000000  0.000000e+00      2.326681  0.0000000000
489      2.238589  0.0000000000  0.000000e+00      2.257781  0.0011781690
492      2.262202  0.0000000000  0.000000e+00      2.289446  0.0000000000
499      2.322810  0.0000000000  0.000000e+00      2.294811  0.0048814111
500      2.036715  0.0000000000  3.696960e-04      2.158243  0.0000000000
    Group.2_beta2
2    0.000000e+00
4   -1.970172e-04
6    0.000000e+00
7    0.000000e+00
8    5.367678e-05
12   9.493862e-04
19   0.000000e+00
21   0.000000e+00
22   0.000000e+00
23   8.397853e-06
26  -1.042639e-04
30   1.792519e-04
33   3.937433e-05
36  -2.592705e-04
37  -2.715811e-05
39   1.218835e-04
41   6.560827e-04
44  -2.571824e-04
45  -1.445836e-05
50   0.000000e+00
51  -5.988209e-05
52  -4.014217e-05
56   8.932260e-04
58   2.479175e-05
59   0.000000e+00
62  -1.631511e-04
63   5.997232e-05
64   0.000000e+00
68   7.436907e-04
73  -2.426935e-03
74   3.257955e-04
76   0.000000e+00
82   0.000000e+00
84   0.000000e+00
87   3.362039e-04
89  -9.411468e-04
96   0.000000e+00
103  0.000000e+00
107  0.000000e+00
108  1.134680e-04
113 -8.322032e-06
116  0.000000e+00
117  0.000000e+00
119  0.000000e+00
120  1.690877e-04
123 -1.812591e-03
130  1.049909e-03
133  0.000000e+00
134  0.000000e+00
139 -5.006238e-05
141  0.000000e+00
142 -6.049560e-05
144  0.000000e+00
154 -2.719499e-05
157  0.000000e+00
158 -3.500778e-04
161  2.033288e-04
165  3.006408e-04
168  1.186102e-04
170  0.000000e+00
174  1.372342e-04
176 -4.937892e-05
178  0.000000e+00
182 -5.006441e-04
183  0.000000e+00
184  5.268376e-05
185  3.834150e-04
187  0.000000e+00
189  8.063386e-05
190  0.000000e+00
191 -2.297591e-04
196  2.113129e-04
200  7.181383e-04
202 -1.856245e-04
205 -2.141963e-05
207  3.616112e-04
208  0.000000e+00
211  3.679593e-04
216  1.094675e-04
219 -5.462265e-06
222  4.717885e-05
223  4.804638e-05
224  0.000000e+00
226  5.524054e-04
229  0.000000e+00
233  0.000000e+00
234 -2.008486e-05
236  7.909217e-05
245 -2.563790e-04
248  0.000000e+00
250  1.228751e-04
251 -1.563112e-03
253 -1.838741e-05
256  1.515585e-04
257  0.000000e+00
261  0.000000e+00
262  4.657486e-05
269  1.115007e-04
270  0.000000e+00
272  1.358671e-04
274  2.928949e-04
277  2.397889e-04
279 -2.642898e-05
280  0.000000e+00
282  0.000000e+00
285 -2.247618e-05
288  8.592092e-05
289  0.000000e+00
295 -1.293603e-03
306  0.000000e+00
308  6.393607e-05
310  0.000000e+00
311  0.000000e+00
315  1.398847e-04
317  0.000000e+00
320 -6.651760e-04
325 -3.295698e-05
326  0.000000e+00
331 -9.905252e-06
332  3.594817e-04
335  0.000000e+00
336 -6.207429e-05
339  5.660818e-04
343  0.000000e+00
348  0.000000e+00
353 -1.006109e-04
354  0.000000e+00
355 -1.444874e-03
358  8.156666e-06
363 -1.141111e-04
364  1.004480e-03
365 -2.020067e-04
366  6.375312e-05
372  8.670415e-05
375  5.645483e-04
380  6.805057e-05
381 -1.759208e-04
382  0.000000e+00
384  0.000000e+00
387  1.385304e-04
388  0.000000e+00
391  2.556517e-04
392  0.000000e+00
394 -1.342143e-04
395 -4.470383e-05
396 -8.864988e-06
401  1.115521e-04
403 -1.851858e-03
409 -2.636813e-04
410 -1.456808e-04
411  0.000000e+00
413  0.000000e+00
416  1.879161e-03
420 -8.570545e-05
422 -2.461198e-05
425  0.000000e+00
426  0.000000e+00
430  0.000000e+00
431  0.000000e+00
437  2.356723e-04
439  7.290180e-05
444 -5.169979e-04
445  0.000000e+00
446  1.699345e-04
447 -1.181622e-03
450  0.000000e+00
451  3.409855e-04
453  0.000000e+00
456  0.000000e+00
457  0.000000e+00
460  1.256131e-04
462 -2.469769e-06
463  8.011289e-04
465  2.458399e-05
466 -9.989073e-05
468 -2.295673e-05
469  3.881486e-04
473 -1.602480e-03
474  0.000000e+00
475  4.604580e-04
478 -3.922510e-04
479  0.000000e+00
482  4.058195e-04
484  2.038019e-04
486  0.000000e+00
489  0.000000e+00
492  0.000000e+00
499 -2.009119e-04
500  3.696960e-04

$sig.pvalues
         p-value R-squared p.valor_beta0 p.valor_Group.2vsGroup.1
2   1.527375e-11 0.5081206 2.456990e-109             2.703534e-08
4   7.850667e-09 0.4634433  1.214060e-98                       NA
6   1.909168e-09 0.4505929 2.384086e-121             3.314073e-07
7   1.174454e-05 0.3034469 4.506999e-102             7.185112e-05
8   2.409309e-06 0.3750073  1.086706e-85             1.253418e-05
12  7.271254e-07 0.3899586  2.733230e-65                       NA
19  6.177327e-09 0.4269617  8.663200e-66             6.394794e-07
21  1.095701e-09 0.4558424  7.707028e-96             2.448756e-07
22  1.172877e-06 0.3490202 5.509680e-102             1.528055e-05
23  3.271694e-03 0.2099914 1.365579e-113             8.614558e-02
26  1.857285e-10 0.5346962  2.629976e-98                       NA
30  1.284219e-11 0.5615923  4.012378e-92             2.526452e-02
33  5.162403e-05 0.3485456 1.691290e-101             7.156890e-04
36  7.516649e-03 0.2410030  8.952239e-44                       NA
37  4.171126e-06 0.3653619  5.056398e-91             1.199619e-03
39  2.614811e-08 0.4437192  3.816053e-63             5.033995e-07
41  2.050556e-06 0.3709436  5.735486e-72                       NA
44  5.785270e-08 0.4357120  5.053336e-92                       NA
45  1.233799e-07 0.4248142 1.115610e-101             1.230967e-06
50  3.393028e-04 0.2255631  1.513277e-97             8.441319e-04
51  6.687046e-05 0.3423568  3.414546e-89             3.159796e-04
52  3.334926e-03 0.2775882  2.739197e-96                       NA
56  1.043583e-09 0.4854482  8.128534e-70                       NA
58  2.010233e-12 0.5557382  1.074330e-92             4.829105e-09
59  1.833412e-04 0.2610849  3.566830e-55             1.574054e-04
62  3.921970e-07 0.4371848  7.780523e-87             7.427000e-02
63  1.775170e-09 0.5096045  1.137064e-93             6.410461e-07
64  1.235948e-04 0.2505078 4.166387e-101             3.918629e-04
68  2.147181e-06 0.3692984  1.143882e-70                       NA
73  5.276439e-09 0.4448415  9.078145e-50                       NA
74  6.159237e-18 0.6645752  4.620837e-82             2.988443e-04
76  5.763162e-05 0.2686735  7.834940e-93             2.230565e-04
82  6.411142e-05 0.2651977  8.438171e-93             2.411261e-04
84  8.188080e-07 0.3848922  3.024538e-46             5.423347e-03
87  2.927348e-04 0.3097574  6.027822e-78             2.886832e-03
89  3.653982e-03 0.2258290  3.634747e-52             8.844076e-04
96  1.920705e-07 0.3806349  2.727222e-91             4.856437e-06
103 5.500276e-04 0.2131274 7.776026e-106             1.229559e-03
107 6.380580e-07 0.3599604 5.906316e-105             1.032314e-05
108 8.116507e-10 0.4887108  9.377309e-71             7.909936e-08
113 1.263697e-05 0.3439000 5.319030e-115             2.448857e-05
116 2.932993e-04 0.2287773  2.867024e-93             7.545134e-04
117 2.185355e-06 0.3294446  1.456535e-68             2.300286e-05
119 9.940118e-05 0.2301628  3.607087e-48             3.348443e-04
120 3.577110e-03 0.2968348  2.291435e-36             3.749416e-03
123 3.050213e-14 0.6187920  1.373184e-47             7.557814e-03
130 1.529846e-05 0.3372815  3.955922e-63                       NA
133 3.207215e-11 0.4998579  3.734988e-82             3.905342e-08
134 4.896490e-04 0.2156941  1.057594e-82             1.122674e-03
139 1.028013e-05 0.3809693  3.365660e-92             8.765383e-05
141 9.481178e-06 0.3081086  2.701785e-82             6.195591e-05
142 6.138452e-03 0.2281966  1.049655e-75             2.963190e-03
144 2.046865e-09 0.4498673  4.448785e-98             3.443686e-07
154 1.370523e-03 0.2346125 8.554294e-101             1.530645e-02
157 1.541130e-08 0.4207329  4.942604e-90             1.075053e-06
158 2.725173e-03 0.2088677  6.233932e-47             3.850749e-03
161 9.893675e-07 0.3842899  1.893974e-59             5.151336e-06
165 1.281443e-04 0.2934429  9.892720e-83                       NA
168 1.976987e-07 0.4475032  3.245315e-93             4.711284e-02
170 3.445983e-04 0.2210672  1.256649e-95             8.543335e-04
174 1.577455e-08 0.4553830 3.959403e-101                       NA
176 2.769670e-06 0.4042187  2.348806e-89             1.280948e-05
178 5.123105e-08 0.4020191  1.260726e-82             2.178165e-06
182 3.069652e-03 0.2040166  1.489814e-69                       NA
183 3.608229e-04 0.2218703  4.339644e-84             8.852647e-04
184 4.478310e-17 0.6532785 1.227225e-110             4.582566e-04
185 1.258684e-10 0.5390957  4.336191e-77             6.194974e-02
187 9.773219e-06 0.3058367  5.089844e-89             6.326788e-05
189 7.648366e-07 0.4265309  2.229304e-83             7.013982e-06
190 2.390025e-10 0.4768990 6.587244e-104             1.089071e-07
191 1.382306e-08 0.4801588  1.121650e-84                       NA
196 4.110648e-08 0.4412244  3.260547e-96                       NA
200 2.860250e-05 0.3175381  9.720799e-67                       NA
202 3.553018e-04 0.3052583  1.086182e-44             1.148798e-04
205 2.203155e-05 0.3325227 2.102295e-112                       NA
207 3.103507e-06 0.4029066  1.876183e-71             5.035493e-02
208 3.162483e-08 0.4098368  3.264530e-87             1.635893e-06
211 2.977298e-28 0.7588259  1.176341e-83             2.454268e-05
216 8.427528e-06 0.3846945  3.399266e-91             5.180331e-02
219 1.535141e-03 0.2161057  1.856570e-74                       NA
222 1.369701e-04 0.2826665  7.450293e-79             1.264660e-04
223 1.829011e-03 0.2270372 3.747649e-112                       NA
224 2.895078e-08 0.4106030 1.647375e-105             1.552456e-06
226 8.529944e-25 0.7339675  1.113538e-78             6.136228e-04
229 1.942324e-06 0.3398095  3.430324e-92             2.125712e-05
233 5.538579e-10 0.4653607  9.387248e-93             1.697174e-07
234 1.173541e-05 0.3459602  9.902350e-98             2.292392e-05
236 1.492212e-05 0.3338127  5.261660e-69             2.573569e-05
245 5.850073e-03 0.2244975  4.749859e-59             7.556400e-03
248 6.936542e-07 0.3573739  1.318153e-86             1.089141e-05
250 1.416060e-06 0.4157562  2.944744e-93                       NA
251 7.392729e-10 0.4956829  7.926011e-47             2.553131e-02
253 3.339696e-17 0.6382422 7.471849e-117             1.385646e-10
256 5.875235e-04 0.2934815  2.368296e-72             1.489511e-03
257 5.963411e-10 0.4644053 7.515776e-110             1.765146e-07
261 1.334965e-06 0.3462469 3.848071e-106             1.662351e-05
262 3.580660e-06 0.3948052  4.487462e-69             4.499057e-06
269 3.047705e-12 0.5738387 2.742849e-100             1.213613e-02
270 5.307833e-29 0.7390622  2.376632e-92             1.939141e-14
272 3.215640e-11 0.5523073  2.744055e-78             1.207748e-07
274 7.684398e-07 0.4206307  2.221379e-72             8.881442e-02
277 7.733023e-08 0.4575833  1.758658e-81             2.378834e-02
279 6.428930e-03 0.2583538 3.421948e-100             2.383415e-02
280 6.559073e-05 0.2627655  2.108195e-86             2.451889e-04
282 3.492294e-04 0.2245301  5.982012e-94             8.631924e-04
285 4.094761e-14 0.5892684 6.441800e-107             1.131894e-05
288 9.040088e-08 0.4583594 8.350527e-101             3.040095e-02
289 7.428060e-05 0.2629297 1.077861e-103             2.686281e-04
295 6.133517e-07 0.3918146  6.406513e-60                       NA
306 5.998785e-07 0.3610902  1.934566e-90             9.925198e-06
308 2.469476e-09 0.4717684  3.884704e-78             1.357724e-07
310 4.517520e-12 0.5210169  1.709846e-85             1.498347e-08
311 1.170666e-06 0.3489080 7.616542e-102             1.526190e-05
315 5.580113e-29 0.7625324  1.341737e-94             3.515728e-07
317 1.748967e-09 0.4504531 1.105035e-106             3.158825e-07
320 1.160435e-07 0.4184056  5.195920e-52             5.399750e-02
325 5.224397e-22 0.6964433  4.748205e-85             2.002248e-12
326 2.021359e-05 0.2924550 2.698815e-113             1.051157e-04
331 2.021518e-08 0.4518516 2.358500e-113             4.321810e-07
332 7.399878e-19 0.6764317  1.380333e-82             9.148833e-04
335 1.376104e-04 0.2477634 2.698734e-100             4.246900e-04
336 5.819285e-03 0.2270565  1.174833e-67             1.144614e-03
339 1.837215e-25 0.7398656  8.333717e-78             3.597503e-04
343 2.501677e-05 0.2868175 1.005179e-102             1.222662e-04
348 1.798334e-13 0.5481405  5.973538e-73             3.380581e-09
353 5.148272e-05 0.3490858  1.972799e-91             3.440640e-04
354 7.768160e-07 0.3567644  7.911669e-93             1.171027e-05
355 7.228828e-04 0.2805268  7.285355e-53             4.960492e-02
358 1.952215e-05 0.4228713  2.682649e-94             7.303405e-04
363 2.326907e-04 0.3166584  2.262359e-76             1.109893e-03
364 1.510712e-07 0.4142822  3.999875e-66                       NA
365 2.942537e-03 0.2805893  1.184051e-64             5.555912e-03
366 4.149673e-03 0.2984482  2.847244e-35             1.290740e-03
372 2.692536e-29 0.7642562 7.742490e-102             2.582243e-07
375 1.047210e-10 0.5356225  1.003460e-63             1.381494e-02
380 6.837169e-08 0.4340547 9.886469e-117                       NA
381 2.464953e-04 0.3136608  2.137849e-88             2.148889e-03
382 1.047091e-17 0.6250830 9.335201e-111             6.247878e-11
384 6.519318e-07 0.3589958  4.604621e-76             1.047422e-05
387 2.219960e-20 0.6930510  1.389676e-91             4.451150e-06
388 6.968497e-16 0.6169009  5.498856e-78             1.642608e-06
391 5.277656e-17 0.6529914  4.335698e-86             3.162247e-03
392 3.219736e-03 0.2105075 5.818732e-112                       NA
394 2.297700e-04 0.3151978  9.744957e-94                       NA
395 4.589128e-04 0.2987030  9.466680e-93             9.599375e-04
396 2.373371e-03 0.2192190 8.306201e-103             5.563595e-03
401 1.093859e-07 0.4552315  1.996588e-91             1.012615e-02
403 2.177013e-03 0.2158321  2.065092e-43                       NA
409 2.862633e-03 0.2161524  2.379325e-55             1.284230e-02
410 1.359101e-02 0.2648880  2.028687e-77             9.588660e-03
411 5.041084e-04 0.2161253  1.746179e-92             1.148439e-03
413 6.201844e-10 0.4641196  2.711189e-46             1.849697e-07
416 1.302494e-08 0.4385336  3.728935e-57                       NA
420 2.789288e-05 0.3276645 1.261833e-104                       NA
422 4.121446e-04 0.2653346  1.737870e-89             1.003472e-02
425 9.377503e-04 0.2021602  1.355992e-54             1.879778e-03
426 1.750324e-07 0.3782261  6.892132e-71             4.591448e-06
430 7.570350e-05 0.2641641  3.199065e-80             2.724126e-04
431 4.622788e-04 0.2183293 7.390353e-113             1.073204e-03
437 6.555466e-33 0.7844846  2.987056e-89             7.184353e-07
439 1.435960e-06 0.3846480 1.204537e-110                       NA
444 1.169558e-04 0.2371211  1.582824e-53                       NA
445 9.046374e-08 0.3934486  4.438019e-96             3.063851e-06
446 2.325630e-21 0.7025808  4.040375e-92             7.351197e-05
447 1.837567e-05 0.3828157  1.175273e-36                       NA
450 7.469322e-07 0.3948947  3.501859e-93             5.523583e-06
451 2.963704e-17 0.6566033  2.426981e-80             4.171584e-04
453 3.367803e-05 0.2807404 4.799463e-101             1.512020e-04
456 1.857590e-05 0.2946908  7.695814e-99             9.903694e-05
457 1.659046e-05 0.2919513  8.203461e-93             9.147095e-05
460 1.456790e-09 0.5122932  2.451862e-96             2.333003e-02
462 6.349668e-05 0.3292312  2.364865e-40             2.029403e-02
463 1.309500e-03 0.2316385  1.615558e-61                       NA
465 1.862034e-03 0.2261529 4.608337e-117                       NA
466 1.595240e-05 0.3403297 4.374523e-101                       NA
468 1.140242e-03 0.2402211  2.428943e-88             6.386665e-03
469 1.888460e-03 0.2247621  3.657150e-43                       NA
473 3.165479e-03 0.2323819  1.631418e-26             1.306470e-02
474 1.232743e-05 0.3025134  9.356910e-94             7.431920e-05
475 8.750881e-11 0.5353623  5.003885e-69             2.604093e-03
478 2.811454e-05 0.3287499  2.057460e-78                       NA
479 6.252141e-07 0.3607788 4.651884e-111             1.018987e-05
482 1.007471e-03 0.2408959  3.163107e-75                       NA
484 5.431796e-12 0.5679490  4.875639e-83             5.492528e-04
486 1.639268e-05 0.2964422  3.014129e-96             9.070190e-05
489 1.417396e-06 0.3829828  4.214530e-83             1.057758e-02
492 6.745757e-06 0.3133341  7.654825e-85             4.903824e-05
499 6.527512e-05 0.3426411  2.204801e-87             2.456041e-04
500 1.456390e-03 0.2316106  2.569770e-38             3.302488e-02
    p.valor_Time p.valor_TimexGroup.2 p.valor_Time2 p.valor_Time2xGroup.2
2             NA                   NA            NA                    NA
4             NA         2.776041e-07            NA          3.756369e-07
6             NA                   NA            NA                    NA
7             NA                   NA            NA                    NA
8             NA                   NA            NA          4.695328e-03
12            NA         3.610675e-06            NA          6.845323e-06
19            NA                   NA            NA                    NA
21            NA                   NA            NA                    NA
22            NA                   NA            NA                    NA
23            NA                   NA            NA          4.800213e-02
26   0.002068405         9.258193e-07            NA          1.142371e-04
30            NA         2.682602e-03            NA          6.549014e-04
33   0.011387928                   NA  6.464357e-03                    NA
36   0.052083054         5.536738e-03  7.250741e-02          3.588178e-02
37            NA                   NA            NA          4.840887e-02
39            NA                   NA            NA          4.701871e-02
41            NA         1.377102e-05            NA          7.077778e-06
44            NA         8.286804e-07            NA          1.209273e-06
45            NA                   NA            NA          6.563071e-02
50            NA                   NA            NA                    NA
51   0.057602693                   NA  2.981640e-02                    NA
52   0.054353566         5.466178e-03  8.171642e-02          3.248619e-03
56            NA         9.887824e-08            NA          3.881468e-07
58            NA                   NA            NA          5.599354e-02
59            NA         1.824445e-02            NA                    NA
62            NA         1.858628e-02            NA          9.280606e-03
63   0.008256002                   NA  5.943510e-03                    NA
64            NA                   NA            NA                    NA
68            NA         7.710807e-06            NA          1.130179e-05
73            NA         9.479117e-07            NA          2.094737e-07
74            NA         7.215474e-03            NA          4.205224e-04
76            NA                   NA            NA                    NA
82            NA                   NA            NA                    NA
84            NA         4.760896e-02            NA                    NA
87            NA         4.535063e-03            NA          1.474148e-03
89            NA         2.771851e-02            NA          4.076912e-02
96            NA                   NA            NA                    NA
103           NA                   NA            NA                    NA
107           NA                   NA            NA                    NA
108           NA                   NA            NA          7.332480e-03
113           NA                   NA            NA          3.628987e-02
116           NA                   NA            NA                    NA
117           NA                   NA            NA                    NA
119           NA                   NA            NA                    NA
120  0.016457943         3.761500e-02  9.365492e-03          2.949642e-02
123           NA         1.859176e-03            NA          2.706200e-04
130           NA         3.196546e-05            NA          3.304407e-05
133           NA                   NA            NA                    NA
134           NA                   NA            NA                    NA
139  0.069663902                   NA  3.208339e-02                    NA
141           NA                   NA            NA                    NA
142           NA         4.145211e-02  1.249861e-02                    NA
144           NA                   NA            NA                    NA
154           NA                   NA            NA          1.655081e-03
157           NA                   NA            NA                    NA
158           NA                   NA            NA          1.424620e-02
161           NA                   NA            NA          1.072160e-02
165           NA         1.210121e-04            NA          2.473227e-04
168           NA         2.501227e-02            NA          1.267272e-02
170           NA                   NA            NA                    NA
174           NA         1.409912e-06            NA          2.452470e-05
176  0.080636991                   NA  6.626821e-02                    NA
178           NA                   NA            NA                    NA
182           NA         5.949328e-03            NA          1.966894e-03
183           NA                   NA            NA                    NA
184           NA         8.948837e-03            NA          4.733261e-03
185           NA         1.984953e-03            NA          8.923340e-04
187           NA                   NA            NA                    NA
189  0.019681655                   NA            NA          9.355660e-05
190           NA                   NA            NA                    NA
191           NA         3.235764e-05  1.936334e-02          4.026682e-03
196           NA         6.503580e-07            NA          1.347188e-06
200           NA         5.189610e-05            NA          1.852887e-04
202           NA                   NA  4.309089e-02          1.179232e-02
205           NA         1.654723e-02  3.393868e-05                    NA
207           NA         5.890828e-02            NA          1.593492e-02
208           NA                   NA            NA                    NA
211           NA         3.723828e-04            NA          2.651050e-05
216           NA         7.067143e-02            NA          3.455419e-02
219           NA                   NA  8.692010e-04          1.114272e-02
222           NA                   NA            NA          8.542610e-02
223           NA         1.418188e-03            NA          4.788982e-03
224           NA                   NA            NA                    NA
226           NA         9.684147e-05            NA          3.299476e-06
229           NA                   NA            NA                    NA
233           NA                   NA            NA                    NA
234           NA                   NA            NA          4.029112e-02
236           NA                   NA            NA          7.317294e-02
245  0.043713559                   NA  4.584633e-02                    NA
248           NA                   NA            NA                    NA
250  0.066332190         1.525066e-05            NA          4.112285e-04
251           NA         8.077861e-03            NA          2.347559e-03
253           NA                   NA            NA          3.684012e-06
256  0.029570217                   NA  2.499848e-02                    NA
257           NA                   NA            NA                    NA
261           NA                   NA            NA                    NA
262           NA                   NA  2.838187e-02          1.331537e-02
269           NA         3.991261e-03            NA          8.678833e-04
270           NA                   NA            NA                    NA
272  0.022973674                   NA  7.476048e-03                    NA
274           NA         3.388015e-02            NA          4.069078e-02
277           NA         3.843671e-02            NA          9.182942e-03
279  0.028742696         2.607051e-02  3.141612e-02                    NA
280           NA                   NA            NA                    NA
282           NA                   NA            NA                    NA
285           NA                   NA            NA          4.334726e-04
288           NA         5.749744e-02            NA          6.759391e-03
289           NA                   NA            NA                    NA
295           NA         5.064923e-06            NA          3.056442e-06
306           NA                   NA            NA                    NA
308           NA                   NA            NA          2.409399e-02
310           NA                   NA            NA                    NA
311           NA                   NA            NA                    NA
315           NA         1.431739e-02            NA          1.894766e-03
317           NA                   NA            NA                    NA
320           NA                   NA            NA          1.253262e-06
325           NA                   NA            NA          7.197284e-02
326           NA                   NA            NA                    NA
331           NA                   NA            NA          2.272546e-02
332           NA         1.941042e-03            NA          6.587480e-05
335           NA                   NA            NA                    NA
336           NA         8.759660e-03  8.996482e-02                    NA
339           NA         1.156096e-04            NA          4.141637e-06
343           NA                   NA            NA                    NA
348           NA                   NA            NA                    NA
353           NA         6.420105e-02            NA          4.628169e-02
354           NA                   NA            NA                    NA
355           NA         5.092230e-03            NA          9.573031e-04
358  0.055244342         9.596695e-02  3.862651e-02          7.189519e-02
363  0.080969609                   NA  3.512738e-02                    NA
364           NA         2.036934e-06            NA          1.490571e-06
365  0.008063850                   NA  3.662638e-03          9.050816e-02
366  0.014889141         4.991394e-02  2.360720e-02          7.851553e-02
372           NA         1.852267e-02            NA          3.812867e-03
375           NA         1.792615e-02            NA          1.759370e-02
380           NA         8.764511e-07            NA          2.547190e-06
381           NA         1.310576e-02            NA          4.680481e-03
382           NA                   NA            NA                    NA
384           NA                   NA            NA                    NA
387           NA         6.121237e-02            NA          8.334080e-03
388           NA         3.313063e-02            NA                    NA
391           NA         1.121867e-03            NA          3.843681e-04
392  0.028604634         1.602313e-03            NA                    NA
394           NA         1.077954e-03  5.748290e-02          1.505589e-04
395  0.083956524                   NA  4.851619e-02                    NA
396           NA                   NA  7.415084e-02                    NA
401           NA         8.570816e-02            NA          3.076146e-02
403           NA         1.098287e-03            NA          1.613388e-03
409           NA                   NA            NA          4.260189e-03
410  0.068901301         1.188735e-03  4.813246e-02          7.798916e-04
411           NA                   NA            NA                    NA
413           NA                   NA            NA                    NA
416           NA         4.147783e-07            NA          4.430801e-07
420           NA         1.069453e-04            NA          8.339095e-04
422           NA                   NA            NA          9.934834e-02
425           NA                   NA            NA                    NA
426           NA                   NA            NA                    NA
430           NA                   NA            NA                    NA
431           NA                   NA            NA                    NA
437           NA         1.535011e-03            NA          1.797604e-04
439           NA         1.432641e-05            NA          1.403349e-04
444           NA                   NA            NA          4.079068e-04
445           NA                   NA            NA                    NA
446           NA         4.287296e-03            NA          1.129057e-03
447  0.019038271         6.155768e-05  4.765974e-02          1.098457e-03
450           NA         6.854842e-02            NA                    NA
451           NA         6.386860e-03            NA          6.324795e-04
453           NA                   NA            NA                    NA
456           NA                   NA            NA                    NA
457           NA                   NA            NA                    NA
460           NA         1.234460e-02            NA          2.266726e-03
462           NA                   NA  1.203588e-02          5.926476e-02
463           NA         7.394728e-04            NA          1.151517e-03
465           NA         8.743931e-03            NA          5.495970e-02
466           NA         1.090019e-04            NA          1.116802e-03
468           NA                   NA  2.944325e-02                    NA
469           NA                   NA  1.674299e-02          1.022521e-03
473  0.013440015                   NA  2.042969e-02                    NA
474           NA                   NA            NA                    NA
475           NA         4.331493e-02            NA          1.087048e-02
478           NA         1.593501e-03            NA          1.606350e-04
479           NA                   NA            NA                    NA
482           NA         1.276443e-03            NA          6.103256e-04
484           NA         8.161021e-02            NA          1.529476e-02
486           NA                   NA            NA                    NA
489           NA         2.902350e-02            NA                    NA
492           NA                   NA            NA                    NA
499           NA         4.439116e-03            NA          2.427570e-03
500           NA                   NA  5.690676e-03                    NA

$g
[1] 189

$edesign
        Time Replicate Group.1 Group.2
G1.T1.1    0         1       1       0
G1.T2.1    0         1       1       0
G1.T6.1    0         1       1       0
G1.T3.1    0         1       1       0
G1.T4.1    2         2       1       0
G1.T5.1    2         2       1       0
G1.T1.2    2         2       1       0
G1.T2.2    2         2       1       0
G1.T6.2    4         3       1       0
G1.T5.2    4         3       1       0
G1.T1.3    4         3       1       0
G1.T2.3    6         4       1       0
G1.T6.3    6         4       1       0
G1.T3.3    6         4       1       0
G1.T4.3    9         5       1       0
G1.T5.3    9         5       1       0
G1.T1.4    9         5       1       0
G1.T2.4    9         5       1       0
G1.T6.4   24         6       1       0
G1.T3.4   24         6       1       0
G1.T4.4   24         6       1       0
G1.T5.4   24         6       1       0
G2.T1.1    0         7       0       1
G2.T2.1    0         7       0       1
G2.T6.1    0         7       0       1
G2.T3.1    0         7       0       1
G2.T4.1    2         8       0       1
G2.T5.1    2         8       0       1
G2.T1.2    2         8       0       1
G2.T2.2    2         8       0       1
G2.T6.2    4         9       0       1
G2.T3.2    4         9       0       1
G2.T4.2    4         9       0       1
G2.T5.2    4         9       0       1
G2.T1.3    6        10       0       1
G2.T2.3    6        10       0       1
G2.T6.3    6        10       0       1
G2.T3.3    6        10       0       1
G2.T4.3    9        11       0       1
G2.T5.3    9        11       0       1
G2.T1.4    9        11       0       1
G2.T2.4    9        11       0       1
G2.T6.4   24        12       0       1
G2.T3.4   24        12       0       1
G2.T4.4   24        12       0       1
G2.T5.4   24        12       0       1
endo_sig_genes$summary$Group.2vsGroup.1
  [1] 2   4   6   7   8   12  19  21  22  23  26  30  33  36  37  39  41 
 [18] 44  45  50  51  52  56  58  59  62  63  64  68  73  74  76  82  84 
 [35] 87  89  96  103 107 108 113 116 117 119 120 123 130 133 134 139 141
 [52] 142 144 154 157 158 161 165 168 170 174 176 178 182 183 184 185 187
 [69] 189 190 191 196 200 202 205 207 208 211 216 219 222 223 224 226 229
 [86] 233 234 236 245 248 250 251 253 256 257 261 262 269 270 272 274 277
[103] 279 280 282 285 288 289 295 306 308 310 311 315 317 320 325 326 331
[120] 332 335 336 339 343 348 353 354 355 358 363 364 365 366 372 375 380
[137] 381 382 384 387 388 391 392 394 395 396 401 403 409 410 411 413 416
[154] 420 422 425 426 430 431 437 439 444 445 446 447 450 451 453 456 457
[171] 460 462 463 465 466 468 469 473 474 475 478 479 482 484 486 489 492
[188] 499 500
189 Levels: 103 107 108 113 116 117 119 12 120 123 130 133 134 139 ... 96

Visualization with df = 2

# Gene 2

Gene2 <- t_endo_data[rownames(t_endo_data) == "2", ]
PlotGroups(Gene2, edesign = final_endo_design, show.fit = T, dis = matrix_endo_design$dis, groups.vector = matrix_endo_design$groups.vector, show.lines = F)

# Gene 108 

Gene108 <- t_endo_data[rownames(t_endo_data) == "108", ]
PlotGroups(Gene108, edesign = final_endo_design, show.fit = T, dis = matrix_endo_design$dis, groups.vector = matrix_endo_design$groups.vector, show.lines = F)

# Gene 1

Gene1 <- t_endo_data[rownames(t_endo_data) == "1", ]
PlotGroups(Gene1, edesign = final_endo_design, show.fit = T, dis = matrix_endo_design$dis, groups.vector = matrix_endo_design$groups.vector, show.lines = F)

Compare unadjusted p-value for df = 5 and df = 2

# Obtain unadjusted p-values when df = 2 and when df = 5

p_value_maSigPro_df_2 <- read.csv("../data/p_value_maSigPro_df_2.txt", sep="")

p_value_maSigPro_df_2 <- as.data.frame(p_value_maSigPro_df_2)

dim(p_value_maSigPro_df_2)
[1] 500   1
p_value_maSigPro_df_5 <- read.csv("../data/p_value_maSigPro_df_5.txt", sep="")

p_value_maSigPro_df_5 <- as.data.frame(p_value_maSigPro_df_5)

dim(p_value_maSigPro_df_5)
[1] 500   1
p_value_maSigPro <- cbind(p_value_maSigPro_df_2, p_value_maSigPro_df_5)
colnames(p_value_maSigPro) <- c("Unadjusted p-value when df = 2", 
                                "Unadjusted p-value when df = 5")

# Correlations with significance levels
library(Hmisc)
Loading required package: lattice
Loading required package: survival
Loading required package: Formula
Loading required package: ggplot2

Attaching package: 'Hmisc'
The following object is masked from 'package:widgetTools':

    label
The following objects are masked from 'package:Biobase':

    combine, contents
The following object is masked from 'package:BiocGenerics':

    combine
The following objects are masked from 'package:base':

    format.pval, round.POSIXt, trunc.POSIXt, units
rc <- rcorr(as.matrix(p_value_maSigPro), type="pearson") # Correlation = 0.7163818 and p = approximately 0

flattenCorrMatrix <- function(cormat, pmat) {
  ut <- upper.tri(cormat)
  data.frame(
    row = rownames(cormat)[row(cormat)[ut]],
    column = rownames(cormat)[col(cormat)[ut]],
    cor  =(cormat)[ut],
    p = pmat[ut]
    )
}

flattenCorrMatrix(rc$r, rc$P)
                             row                         column       cor
1 Unadjusted p-value when df = 2 Unadjusted p-value when df = 5 0.7163818
  p
1 0
# Compare unadjusted p-values from df = 2 and df = 5
plot(p_value_maSigPro, 
     main = "Unadjusted p-values from maSigPro (Pearson's corr. = 0.716)")

# Make a best fit line (which we can then add to the plot)
abline(lm(p_value_maSigPro[,1] ~ p_value_maSigPro[,2]))

Session information

R Under development (unstable) (2016-03-11 r70310)
Platform: x86_64-apple-darwin13.4.0 (64-bit)
Running under: OS X 10.10.5 (Yosemite)

locale:
[1] en_US.UTF-8/en_US.UTF-8/en_US.UTF-8/C/en_US.UTF-8/en_US.UTF-8

attached base packages:
[1] tcltk     parallel  stats     graphics  grDevices utils     datasets 
[8] methods   base     

other attached packages:
 [1] Hmisc_3.17-4        ggplot2_2.1.0       Formula_1.2-1      
 [4] survival_2.39-5     lattice_0.20-33     maSigPro_1.44.0    
 [7] DynDoc_1.50.0       widgetTools_1.50.0  MASS_7.3-45        
[10] Biobase_2.32.0      BiocGenerics_0.18.0 knitr_1.14         

loaded via a namespace (and not attached):
 [1] Rcpp_0.12.6         formatR_1.4         RColorBrewer_1.1-2 
 [4] plyr_1.8.4          tkWidgets_1.50.0    tools_3.3.0        
 [7] rpart_4.1-10        digest_0.6.10       evaluate_0.9       
[10] gtable_0.2.0        Matrix_1.2-6        yaml_2.1.13        
[13] gridExtra_2.2.1     stringr_1.0.0       cluster_2.0.4      
[16] grid_3.3.0          nnet_7.3-12         data.table_1.9.6   
[19] foreign_0.8-66      rmarkdown_1.0       limma_3.28.17      
[22] latticeExtra_0.6-28 magrittr_1.5        scales_0.4.0       
[25] htmltools_0.3.5     splines_3.3.0       colorspace_1.2-6   
[28] stringi_1.1.1       Mfuzz_2.32.0        acepack_1.3-3.3    
[31] munsell_0.4.3       chron_2.3-47